Dph2 (diphthamide biosynthesis 2) - Rat Genome Database

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Gene: Dph2 (diphthamide biosynthesis 2) Rattus norvegicus
Analyze
Symbol: Dph2
Name: diphthamide biosynthesis 2
RGD ID: 1304634
Description: Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to contribute to 2-(3-amino-3-carboxypropyl)histidine synthase activity. Predicted to be involved in protein histidyl modification to diphthamide. Predicted to be part of 2-(3-amino-3-carboxypropyl)histidine synthase complex. Human ortholog(s) of this gene implicated in diphthamide deficiency syndrome 2. Orthologous to human DPH2 (diphthamide biosynthesis 2); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; diphthamide biosynthesis protein 2; diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2; DPH2 homolog; DPH2 homolog (S. cerevisiae); Dph2l2; LOC298452; MGC109459; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,713,868 - 136,716,828 (-)NCBIGRCr8
mRatBN7.25131,428,434 - 131,431,394 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,428,268 - 131,431,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5134,133,497 - 134,136,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,888,116 - 135,891,076 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,910,538 - 135,913,498 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,723,398 - 136,726,358 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,723,406 - 136,726,358 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05140,512,447 - 140,515,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,354,594 - 138,357,554 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15138,359,819 - 138,362,780 (-)NCBI
Celera5129,976,628 - 129,979,588 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dph2RatCharcot-Marie-Tooth disease dominant intermediate C  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate CClinVarPMID:28492532
Dph2Ratdevelopmental and epileptic encephalopathy  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathyClinVarPMID:23252400 more ...
Dph2RatDevelopmental Disabilities  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 and PMID:32576952
Dph2Ratdiphthamide deficiency syndrome  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: diphthamide-deficiency syndromeClinVarPMID:25741868 more ...
Dph2Ratdiphthamide deficiency syndrome 2  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental delay with short stature more ...ClinVarPMID:25741868 more ...
Dph2Ratearly infantile epileptic encephalopathy  ISODPH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathyClinVarPMID:23252400 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dph2Ratdiphthamide deficiency syndrome 2  ISODPH2 (Homo sapiens)7240710 OMIM 

1 to 20 of 65 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dph2Rat(1->4)-beta-D-glucan multiple interactionsISODph2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DPH2 mRNACTDPMID:36331819
Dph2Rat1,2-dimethylhydrazine multiple interactionsISODph2 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of DPH2 mRNA]CTDPMID:22206623
Dph2Rat1,2-dimethylhydrazine increases expressionISODph2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of DPH2 mRNACTDPMID:22206623
Dph2Rat17beta-estradiol increases expressionISODPH2 (Homo sapiens)6480464Estradiol results in increased expression of DPH2 mRNACTDPMID:23019147 and PMID:31614463
Dph2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODph2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DPH2 mRNACTDPMID:21570461
Dph2Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of DPH2 proteinCTDPMID:34915118
Dph2Rat4,4'-sulfonyldiphenol increases methylationISODPH2 (Homo sapiens)6480464bisphenol S results in increased methylation of DPH2 geneCTDPMID:31601247
Dph2Ratacrolein multiple interactionsISODPH2 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DPH2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DPH2 mRNACTDPMID:32699268
Dph2Ratacrylamide decreases expressionISODPH2 (Homo sapiens)6480464Acrylamide results in decreased expression of DPH2 mRNACTDPMID:32763439
Dph2Ratall-trans-retinoic acid decreases expressionISODPH2 (Homo sapiens)6480464Tretinoin results in decreased expression of DPH2 mRNACTDPMID:23724009 and PMID:33167477
Dph2Ratalpha-pinene multiple interactionsISODPH2 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DPH2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DPH2 mRNACTDPMID:32699268
Dph2Ratarsane multiple interactionsISODPH2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of DPH2 mRNACTDPMID:39836092
Dph2Ratarsenic atom multiple interactionsISODPH2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of DPH2 mRNACTDPMID:39836092
Dph2Ratarsenous acid multiple interactionsISODPH2 (Homo sapiens)6480464Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DPH2 protein]CTDPMID:26598702
Dph2Ratatrazine decreases expressionISODPH2 (Homo sapiens)6480464Atrazine results in decreased expression of DPH2 mRNACTDPMID:22378314
Dph2Ratbenzo[a]pyrene decreases expressionISODph2 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of DPH2 mRNACTDPMID:19770486
Dph2Ratbenzo[a]pyrene increases expressionISODph2 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of DPH2 mRNACTDPMID:22228805
Dph2Ratbeta-lapachone increases expressionISODPH2 (Homo sapiens)6480464beta-lapachone results in increased expression of DPH2 mRNACTDPMID:38218311
Dph2Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of DPH2 mRNACTDPMID:30816183 more ...
Dph2Ratbisphenol A increases expressionISODph2 (Mus musculus)6480464bisphenol A results in increased expression of DPH2 mRNACTDPMID:33221593

1 to 20 of 65 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dph2Ratprotein histidyl modification to diphthamide involved_inIEAUniPathway:UPA005591600115GO_REF:0000041UniProtGO_REF:0000041
Dph2Ratprotein histidyl modification to diphthamide involved_inIEAInterPro:IPR010014 and InterPro:IPR0164351600115GO_REF:0000002InterProGO_REF:0000002
Dph2Ratprotein histidyl modification to diphthamide involved_inIEAUniProtKB:Q9BQC3 and ensembl:ENSP000002551081600115GO_REF:0000107EnsemblGO_REF:0000107
Dph2Ratprotein histidyl modification to diphthamide involved_inIBAMGI:2151233 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dph2Ratprotein histidyl modification to diphthamide involved_inISODPH2 (Homo sapiens)1624291 PMID:32576952RGDPMID:32576952
Dph2Ratprotein histidyl modification to diphthamide involved_inISSUniProtKB:P324611600115GO_REF:0000024UniProtGO_REF:0000024

Cellular Component

  

Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:20559380  



Dph2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,713,868 - 136,716,828 (-)NCBIGRCr8
mRatBN7.25131,428,434 - 131,431,394 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,428,268 - 131,431,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5134,133,497 - 134,136,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,888,116 - 135,891,076 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,910,538 - 135,913,498 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,723,398 - 136,726,358 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,723,406 - 136,726,358 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05140,512,447 - 140,515,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,354,594 - 138,357,554 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15138,359,819 - 138,362,780 (-)NCBI
Celera5129,976,628 - 129,979,588 (-)NCBICelera
Cytogenetic Map5q36NCBI
DPH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,970,010 - 43,973,369 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,970,000 - 43,973,369 (+)EnsemblGRCh38hg38GRCh38
GRCh37144,435,682 - 44,439,041 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36144,208,240 - 44,211,630 (+)NCBINCBI36Build 36hg18NCBI36
Celera142,719,187 - 42,722,577 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef142,551,206 - 42,554,596 (+)NCBIHuRef
CHM1_1144,551,906 - 44,555,296 (+)NCBICHM1_1
T2T-CHM13v2.0143,841,090 - 43,844,449 (+)NCBIT2T-CHM13v2.0
Dph2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,745,838 - 117,749,220 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4117,745,840 - 117,749,229 (-)EnsemblGRCm39 Ensembl
GRCm384117,888,643 - 117,892,003 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,888,643 - 117,892,032 (-)EnsemblGRCm38mm10GRCm38
MGSCv374117,561,248 - 117,564,608 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364117,386,575 - 117,389,935 (-)NCBIMGSCv36mm8
Celera4116,603,810 - 116,607,170 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.74NCBI
Dph2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555373,496,688 - 3,500,147 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555373,496,688 - 3,500,147 (+)NCBIChiLan1.0ChiLan1.0
DPH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,836,316 - 182,840,190 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11181,977,648 - 181,981,523 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,271,349 - 43,275,162 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,643,142 - 44,646,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,643,142 - 44,646,545 (+)Ensemblpanpan1.1panPan2
DPH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,287,300 - 16,291,079 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,288,370 - 16,291,032 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1516,408,187 - 16,411,963 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01516,441,825 - 16,445,608 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,441,825 - 16,445,591 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,240,687 - 16,244,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,309,692 - 16,313,468 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,382,434 - 16,386,210 (-)NCBIUU_Cfam_GSD_1.0
Dph2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505859,463,929 - 59,467,505 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647425,288,250 - 25,293,382 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647425,288,714 - 25,292,287 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,322,332 - 167,326,241 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16167,322,197 - 167,327,760 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26154,992,168 - 154,992,872 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DPH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12088,832,556 - 88,836,318 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2088,831,322 - 88,836,355 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603328,091,356 - 28,095,097 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dph2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248923,251,270 - 3,254,464 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248923,251,243 - 3,254,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dph2
9 total Variants

Predicted Target Of
Summary Value
Count of predictions:288
Count of miRNA genes:200
Interacting mature miRNAs:232
Transcripts:ENSRNOT00000026739
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat

1 to 10 of 51 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000026739   ⟹   ENSRNOP00000026739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5131,428,268 - 131,431,395 (-)Ensembl
Rnor_6.0 Ensembl5136,723,406 - 136,726,358 (-)Ensembl
RefSeq Acc Id: NM_001015007   ⟹   NP_001015007
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,713,868 - 136,716,828 (-)NCBI
mRatBN7.25131,428,434 - 131,431,394 (-)NCBI
Rnor_6.05136,723,398 - 136,726,358 (-)NCBI
Rnor_5.05140,512,447 - 140,515,407 (-)NCBI
RGSC_v3.45138,354,594 - 138,357,554 (-)RGD
Celera5129,976,628 - 129,979,588 (-)RGD
Sequence:
Protein RefSeqs NP_001015007 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH92656 (Get FASTA)   NCBI Sequence Viewer  
  EDL90200 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026739.4
GenBank Protein Q568Y2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001015007   ⟸   NM_001015007
- UniProtKB: Q568Y2 (UniProtKB/Swiss-Prot),   A6JZF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026739   ⟸   ENSRNOT00000026739

Name Modeler Protein Id AA Range Protein Structure
AF-Q568Y2-F1-model_v2 AlphaFold Q568Y2 1-489 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693959
Promoter ID:EPDNEW_R4483
Type:initiation region
Name:Dph2_1
Description:DPH2 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05136,726,441 - 136,726,501EPDNEW


1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40177 BioCyc
BioCyc Pathway PWY-7546 [diphthamide biosynthesis II (eukaryotes)] BioCyc
BioCyc Pathway Image PWY-7546 BioCyc
Ensembl Genes ENSRNOG00000019735 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026739.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.11840 UniProtKB/Swiss-Prot
  3.40.50.11860 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7320904 IMAGE-MGC_LOAD
InterPro DHP2 UniProtKB/Swiss-Prot
  DPH1/DPH2 UniProtKB/Swiss-Prot
  DPH1/DPH2_1 UniProtKB/Swiss-Prot
  DPH1/DPH2_3 UniProtKB/Swiss-Prot
KEGG Report rno:298452 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109459 IMAGE-MGC_LOAD
NCBI Gene 298452 ENTREZGENE
PANTHER PTHR10762 UniProtKB/Swiss-Prot
  PTHR10762:SF2 UniProtKB/Swiss-Prot
Pfam Diphthamide_syn UniProtKB/Swiss-Prot
PhenoGen Dph2 PhenoGen
RatGTEx ENSRNOG00000019735 RatGTEx
UniProt A6JZF3 ENTREZGENE, UniProtKB/TrEMBL
  DPH2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Dph2  diphthamide biosynthesis 2  Dph2  DPH2 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-09 Dph2  DPH2 homolog  Dph2  DPH2 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dph2  DPH2 homolog (S. cerevisiae)  Dph2l2  diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2  Symbol and Name updated 1299863 APPROVED
2005-12-06 Dph2l2  diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2  Dph2l2_predicted  diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Dph2l2_predicted  diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED