PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: tenoxicam pharmacodynamics pathway
Accession: PW:0001795
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Definition: The pathway of tenoxicam-target interaction and of the biochemical or physiological responses to drug. Tenoxicam is thought to inhibit cyclooxygenases and thus block prostaglandin synthesis. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms: related_synonym: SMP:00706
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AKR1C3
aldo-keto reductase family 1 member C3
EXP
SMPDB
SMP:00706
NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
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ALOX12
arachidonate 12-lipoxygenase, 12S type
EXP
SMPDB
SMP:00706
NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
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ALOX12B
arachidonate 12-lipoxygenase, 12R type
EXP
SMPDB
SMP:00706
NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716
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ALOX15
arachidonate 15-lipoxygenase
EXP
SMPDB
SMP:00706
NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
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ALOX15B
arachidonate 15-lipoxygenase type B
EXP
SMPDB
SMP:00706
NCBI chr17:8,039,059...8,049,134
Ensembl chr17:8,039,034...8,049,134
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ALOX5
arachidonate 5-lipoxygenase
EXP
SMPDB
SMP:00706
NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
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CBR1
carbonyl reductase 1
EXP
SMPDB
SMP:00706
NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
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CYP2B6
cytochrome P450 family 2 subfamily B member 6
EXP
SMPDB
SMP:00706
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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CYP2C8
cytochrome P450 family 2 subfamily C member 8
EXP
SMPDB
SMP:00706
NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
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CYP2E1
cytochrome P450 family 2 subfamily E member 1
EXP
SMPDB
SMP:00706
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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CYP2J2
cytochrome P450 family 2 subfamily J member 2
EXP
SMPDB
SMP:00706
NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
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CYP2U1
cytochrome P450 family 2 subfamily U member 1
EXP
SMPDB
SMP:00706
NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
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CYP4A11
cytochrome P450 family 4 subfamily A member 11
EXP
SMPDB
SMP:00706
NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
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CYP4F2
cytochrome P450 family 4 subfamily F member 2
EXP
SMPDB
SMP:00706
NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
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CYP4F3
cytochrome P450 family 4 subfamily F member 3
EXP
SMPDB
SMP:00706
NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
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CYP4F8
cytochrome P450 family 4 subfamily F member 8
EXP
SMPDB
SMP:00706
NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
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EPHX2
epoxide hydrolase 2
EXP
SMPDB
SMP:00706
NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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GGT1
gamma-glutamyltransferase 1
EXP
SMPDB
SMP:00706
NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
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GPX1
glutathione peroxidase 1
EXP
SMPDB
SMP:00706
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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LTA4H
leukotriene A4 hydrolase
EXP
SMPDB
SMP:00706
NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520
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LTC4S
leukotriene C4 synthase
EXP
SMPDB
SMP:00706
NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
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PLA2G4B
phospholipase A2 group IVB
EXP
SMPDB
SMP:00706
NCBI chr15:41,838,847...41,848,143
Ensembl chr15:41,837,775...41,848,147
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PRXL2B
peroxiredoxin like 2B
EXP
SMPDB
SMP:00706
NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469
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PTGDS
prostaglandin D2 synthase
EXP
SMPDB
SMP:00706
NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
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PTGES
prostaglandin E synthase
EXP
SMPDB
SMP:00706
NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
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PTGIS
prostaglandin I2 synthase
EXP
SMPDB
SMP:00706
NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
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PTGS1
prostaglandin-endoperoxide synthase 1
EXP
SMPDB
SMP:00706
NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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PTGS2
prostaglandin-endoperoxide synthase 2
EXP
SMPDB
SMP:00706
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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TBXAS1
thromboxane A synthase 1
EXP
SMPDB
SMP:00706
NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all