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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:tenoxicam pharmacodynamics pathway
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Accession:PW:0001795 term browser browse the term
Definition:The pathway of tenoxicam-target interaction and of the biochemical or physiological responses to drug. Tenoxicam is thought to inhibit cyclooxygenases and thus block prostaglandin synthesis. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00706



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tenoxicam pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 EXP SMPDB SMP:00706 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP SMPDB SMP:00706 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type EXP SMPDB SMP:00706 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase EXP SMPDB SMP:00706 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B EXP SMPDB SMP:00706 NCBI chr17:8,039,059...8,049,134
Ensembl chr17:8,039,034...8,049,134
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP SMPDB SMP:00706 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G CBR1 carbonyl reductase 1 EXP SMPDB SMP:00706 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP SMPDB SMP:00706 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP SMPDB SMP:00706 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP SMPDB SMP:00706 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 EXP SMPDB SMP:00706 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 EXP SMPDB SMP:00706 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 EXP SMPDB SMP:00706 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484
JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 EXP SMPDB SMP:00706 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 EXP SMPDB SMP:00706 NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 EXP SMPDB SMP:00706 NCBI chr19:15,615,218...15,630,639
Ensembl chr19:15,615,218...15,630,639
JBrowse link
G EPHX2 epoxide hydrolase 2 EXP SMPDB SMP:00706 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G GGT1 gamma-glutamyltransferase 1 EXP SMPDB SMP:00706 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
JBrowse link
G GPX1 glutathione peroxidase 1 EXP SMPDB SMP:00706 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G LTA4H leukotriene A4 hydrolase EXP SMPDB SMP:00706 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520
JBrowse link
G LTC4S leukotriene C4 synthase EXP SMPDB SMP:00706 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G PLA2G4B phospholipase A2 group IVB EXP SMPDB SMP:00706 NCBI chr15:41,838,847...41,848,143
Ensembl chr15:41,837,775...41,848,147
JBrowse link
G PRXL2B peroxiredoxin like 2B EXP SMPDB SMP:00706 NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469
JBrowse link
G PTGDS prostaglandin D2 synthase EXP SMPDB SMP:00706 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
JBrowse link
G PTGES prostaglandin E synthase EXP SMPDB SMP:00706 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G PTGIS prostaglandin I2 synthase EXP SMPDB SMP:00706 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP SMPDB SMP:00706 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP SMPDB SMP:00706 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G TBXAS1 thromboxane A synthase 1 EXP SMPDB SMP:00706 NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5958
    drug pathway 412
      musculo-skeletal system drug pathway 76
        tenoxicam drug pathway 29
          tenoxicam pharmacodynamics pathway 29
paths to the root