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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:phosphatidylinositol metabolic pathway
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Accession:PW:0002417 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of phosphatidylinositol (PtdIns). Phosphorylation of PtdIns can occur at the 3, 4, and/or 5 position of the inositol ring using one or multiple phosphate groups. These phosphorylated forms of PtdIns are known as phosphoinositides.
Synonyms:related_synonym: PI Metabolism;   phosphatidylinositol metabolic process



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phosphoinositide metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 ISO SMPDB SMP:00463 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Becn1 beclin 1 ISO SMPDB SMP:00463 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase ISO SMPDB SMP:00463 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408
JBrowse link
G Egfr epidermal growth factor receptor ISO SMPDB SMP:00463 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO SMPDB SMP:00463 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase ISO SMPDB SMP:00463 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO SMPDB SMP:00463 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO SMPDB SMP:00463 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E ISO SMPDB SMP:00463 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha ISO SMPDB SMP:00463 NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha ISO SMPDB SMP:00463 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 ISO SMPDB SMP:00463 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO SMPDB SMP:00463 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta ISO SMPDB SMP:00463 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO SMPDB SMP:00463 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 ISO SMPDB SMP:00463 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing ISO SMPDB SMP:00463 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO SMPDB SMP:00463 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha ISO SMPDB SMP:00463 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Plcb1 phospholipase C beta 1 ISO SMPDB SMP:00463 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Pten phosphatase and tensin homolog ISO SMPDB SMP:00463 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Synj1 synaptojanin 1 ISO SMPDB SMP:00463 NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Vac14 VAC14 component of PIKFYVE complex ISO SMPDB SMP:00463 NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        glycerophospholipid metabolic pathway 106
          phosphatidylinositol metabolic pathway 23
            altered phosphatidylinositol metabolic pathway + 0
            phosphoinositide metabolic pathway + 23
paths to the root