Pik3r4 (phosphoinositide-3-kinase, regulatory subunit 4) - Rat Genome Database

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Gene: Pik3r4 (phosphoinositide-3-kinase, regulatory subunit 4) Rattus norvegicus
Analyze
Symbol: Pik3r4
Name: phosphoinositide-3-kinase, regulatory subunit 4
RGD ID: 1311809
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including early endosome to late endosome transport; phosphatidylinositol-3-phosphate biosynthetic process; and vacuolar transport. Predicted to be located in axoneme; intracellular membrane-bounded organelle; and microtubule cytoskeleton. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Predicted to be active in late endosome and nucleus-vacuole junction. Orthologous to human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4); PARTICIPATES IN autophagy pathway; inositol metabolic pathway; phosphoinositide metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363131; phosphoinositide 3-kinase regulatory subunit 4; phosphoinositide-3-kinase, regulatory subunit 4, p150; PI3-kinase regulatory subunit 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28106,267,908 - 106,316,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,267,954 - 106,316,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,890,314 - 111,939,993 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08110,089,590 - 110,139,269 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08107,932,278 - 107,981,958 (+)NCBIRnor_WKY
Rnor_6.08114,300,248 - 114,350,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,300,257 - 114,350,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,675,758 - 113,725,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,741,833 - 110,790,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,762,479 - 110,809,819 (+)NCBI
Celera8105,594,747 - 105,643,191 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:12477932   PMID:14617358   PMID:15057822   PMID:19946888   PMID:20643123   PMID:21062745   PMID:23332761   PMID:24089209  


Genomics

Comparative Map Data
Pik3r4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28106,267,908 - 106,316,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,267,954 - 106,316,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,890,314 - 111,939,993 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08110,089,590 - 110,139,269 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08107,932,278 - 107,981,958 (+)NCBIRnor_WKY
Rnor_6.08114,300,248 - 114,350,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8114,300,257 - 114,350,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,675,758 - 113,725,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,741,833 - 110,790,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,762,479 - 110,809,819 (+)NCBI
Celera8105,594,747 - 105,643,191 (+)NCBICelera
Cytogenetic Map8q32NCBI
PIK3R4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383130,678,934 - 130,746,829 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3130,678,934 - 130,746,829 (-)EnsemblGRCh38hg38GRCh38
GRCh373130,397,778 - 130,465,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363131,880,468 - 131,948,386 (-)NCBINCBI36Build 36hg18NCBI36
Build 343131,880,475 - 131,948,348NCBI
Celera3128,823,051 - 128,890,972 (-)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3127,782,400 - 127,850,320 (-)NCBIHuRef
CHM1_13130,360,774 - 130,428,689 (-)NCBICHM1_1
T2T-CHM13v2.03133,422,776 - 133,490,673 (-)NCBIT2T-CHM13v2.0
Pik3r4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,520,156 - 105,564,854 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,520,177 - 105,564,856 (+)EnsemblGRCm39 Ensembl
GRCm389105,642,995 - 105,687,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,642,978 - 105,687,657 (+)EnsemblGRCm38mm10GRCm38
MGSCv379105,545,325 - 105,589,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369105,501,078 - 105,545,755 (+)NCBIMGSCv36mm8
Celera9105,236,861 - 105,284,774 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.79NCBI
Pik3r4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555017,604,501 - 7,681,947 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555017,604,934 - 7,681,947 (+)NCBIChiLan1.0ChiLan1.0
PIK3R4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13135,089,584 - 135,157,193 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3135,089,584 - 135,157,193 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03127,743,873 - 127,834,512 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PIK3R4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,902,500 - 27,973,609 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2327,902,840 - 27,971,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,876,020 - 27,947,053 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02328,409,021 - 28,480,487 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2328,409,029 - 28,480,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12328,103,972 - 28,175,361 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02328,158,914 - 28,236,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02328,414,452 - 28,485,590 (-)NCBIUU_Cfam_GSD_1.0
Pik3r4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560267,401,776 - 67,472,004 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365294,162,112 - 4,232,510 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365294,162,276 - 4,232,471 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3R4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,731,023 - 1,815,556 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,730,988 - 1,815,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,388,518 - 1,533,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11559,444,570 - 59,515,619 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1559,444,616 - 59,515,240 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604132,468,967 - 32,542,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3r4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247306,642,190 - 6,744,470 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247306,642,195 - 6,744,480 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pik3r4
161 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:145
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000018654
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat

Markers in Region
RH141195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28106,316,358 - 106,316,569 (+)MAPPERmRatBN7.2
Rnor_6.08114,350,460 - 114,350,670NCBIRnor6.0
Rnor_5.08113,725,742 - 113,725,952UniSTSRnor5.0
RGSC_v3.48110,790,484 - 110,790,694UniSTSRGSC3.4
Celera8105,642,966 - 105,643,176UniSTS
RH 3.4 Map81151.0UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 6 22 7 19 7 74 35 34 11
Low 37 35 34 34 8 11 7 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000018654   ⟹   ENSRNOP00000018654
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8106,267,982 - 106,316,584 (+)Ensembl
Rnor_6.0 Ensembl8114,300,312 - 114,350,681 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090707   ⟹   ENSRNOP00000070282
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8106,267,982 - 106,316,584 (+)Ensembl
Rnor_6.0 Ensembl8114,300,257 - 114,350,519 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112633   ⟹   ENSRNOP00000083491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8106,267,954 - 106,273,700 (+)Ensembl
RefSeq Acc Id: NM_001108777   ⟹   NP_001102247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28106,267,954 - 106,316,584 (+)NCBI
Rnor_6.08114,300,284 - 114,350,685 (+)NCBI
Rnor_5.08113,675,758 - 113,725,968 (+)NCBI
RGSC_v3.48110,741,833 - 110,790,709 (+)RGD
Celera8105,594,747 - 105,643,191 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243800   ⟹   XP_006243862
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28106,267,915 - 106,316,585 (+)NCBI
Rnor_6.08114,300,257 - 114,350,686 (+)NCBI
Rnor_5.08113,675,758 - 113,725,968 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243801   ⟹   XP_006243863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28106,267,908 - 106,316,585 (+)NCBI
Rnor_6.08114,300,248 - 114,350,686 (+)NCBI
Rnor_5.08113,675,758 - 113,725,968 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001102247   ⟸   NM_001108777
- Sequence:
RefSeq Acc Id: XP_006243863   ⟸   XM_006243801
- Peptide Label: isoform X1
- UniProtKB: P0C0R5 (UniProtKB/Swiss-Prot),   B5DFA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243862   ⟸   XM_006243800
- Peptide Label: isoform X1
- UniProtKB: P0C0R5 (UniProtKB/Swiss-Prot),   B5DFA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018654   ⟸   ENSRNOT00000018654
RefSeq Acc Id: ENSRNOP00000070282   ⟸   ENSRNOT00000090707
RefSeq Acc Id: ENSRNOP00000083491   ⟸   ENSRNOT00000112633
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0R5-F1-model_v2 AlphaFold P0C0R5 1-1358 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696244
Promoter ID:EPDNEW_R6765
Type:initiation region
Name:Pik3r4_1
Description:phosphoinositide-3-kinase, regulatory subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08114,300,265 - 114,300,325EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311809 AgrOrtholog
BioCyc Gene G2FUF-29268 BioCyc
BioCyc Pathway PWY-6352 [3-phosphoinositide biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000013669 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000018654 ENTREZGENE
  ENSRNOP00000018654.4 UniProtKB/Swiss-Prot
  ENSRNOP00000070282.2 UniProtKB/TrEMBL
  ENSRNOP00000083491.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018654 ENTREZGENE
  ENSRNOT00000018654.8 UniProtKB/Swiss-Prot
  ENSRNOT00000090707.2 UniProtKB/TrEMBL
  ENSRNOT00000112633.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vps15-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 363131 ENTREZGENE
PANTHER PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR17583 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pik3r4 PhenoGen
PROSITE HEAT_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A033_RAT UniProtKB/TrEMBL
  A0A8L2R3Q5_RAT UniProtKB/TrEMBL
  B5DFA2 ENTREZGENE, UniProtKB/TrEMBL
  P0C0R5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Pik3r4  phosphoinositide-3-kinase, regulatory subunit 4  Pik3r4  phosphoinositide-3-kinase, regulatory subunit 4, p150  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pik3r4  phosphoinositide-3-kinase, regulatory subunit 4, p150   Pik3r4_predicted  phosphoinositide-3-kinase, regulatory subunit 4, p150 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pik3r4_predicted  phosphoinositide-3-kinase, regulatory subunit 4, p150 (predicted)      Symbol and Name status set to approved 70820 APPROVED