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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of Fc receptor mediated stimulatory signaling pathway
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Accession:GO:0060368 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: regulation of Fc receptor mediated stimulatory signalling pathway


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regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:9325302, PMID:21873635 RGD:2303720, RGD:13792537 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in IMP PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (MGI:3050742|PMID:15235600), (MGI:3834538|PMID:17341663) RGD PMID:15235600 PMID:17341663 MGI:3050742 MGI:3834538 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6271154|PMID:25568335) RGD PMID:25568335 MGI:6271154 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Cd47 Cd47 molecule involved_in IMP PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr18:87,415,531...87,415,884 JBrowse link
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:16831868)
PMID:21873635
RGD PMID:16831868, PMID:21873635 RGD:13792537 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) RGD PMID:25568335 MGI:6271154 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:Q64455 (MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:3774343 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO UniProtKB:P06800 (MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:3774343 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IMP RGD PMID:18832707 RGD:9835043 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:18832707 RGD:9835043 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976
JBrowse link
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc fragment of IgG receptor IIa IMP RGD PMID:22184119, PMID:16482158 RGD:11041001, RGD:2293335 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      signal transduction 6956
        regulation of signal transduction 2964
          regulation of Fc receptor mediated stimulatory signaling pathway 14
            positive regulation of Fc receptor mediated stimulatory signaling pathway + 8
            regulation of Fc-gamma receptor signaling pathway involved in phagocytosis + 8
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13584
      regulation of biological process 12857
        regulation of immune system process 1471
          regulation of immune response 864
            positive regulation of immune response 638
              activation of immune response 406
                immune response-activating signal transduction 324
                  immune response-activating cell surface receptor signaling pathway 323
                    Fc receptor mediated stimulatory signaling pathway 19
                      regulation of Fc receptor mediated stimulatory signaling pathway 14
                        positive regulation of Fc receptor mediated stimulatory signaling pathway + 8
                        regulation of Fc-gamma receptor signaling pathway involved in phagocytosis + 8
paths to the root