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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-activating cell surface receptor signaling pathway
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Accession:GO:0002429 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.
Synonyms:exact_synonym: activation of immune response by cell surface receptor signaling pathway;   immune response-activating cell surface receptor signalling pathway


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immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO
IEA 		(PMID:18852879)
GO_REF:0000107 		RGD
Ensembl		 PMID:18852879 GO_REF:0000107 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Micb MHC class I polypeptide-related sequence B involved_in ISO (PMID:11491531) RGD PMID:11491531 NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827 		JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISS
IBA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:18852879) 		UniProt
GO_Central
Ensembl
InterPro
RGD		 PMID:18852879 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799 		JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
IEA
ISS 		(PMID:10587647)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:10587647 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Cd19 CD19 molecule involved_in ISO
IEA 		(PMID:1373518)
GO_REF:0000107 		RGD
Ensembl		 PMID:1373518 GO_REF:0000107 NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3579135 (PMID:15843560) 		GO_Central
RGD		 PMID:15843560 GO_REF:0000033 NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:26,063,812...26,093,468
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA 		(PMID:15214043)
GO_REF:0000107 		RGD
Ensembl		 PMID:15214043 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) RGD PMID:23728777 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO
IEA 		MGI:2153718 (PMID:11120811), (PMID:19228876)
GO_REF:0000107 		RGD
Ensembl		 PMID:11120811 PMID:19228876 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
IEA
ISS 		(PMID:9020138)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:9020138 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA 		UniProtKB:Q8NDB2 (PMID:23555801), (PMID:876631)
GO_REF:0000107 		RGD
Ensembl		 PMID:876631 PMID:23555801 GO_REF:0000107 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031 		JBrowse link
G Blnk B-cell linker involved_in ISO (PMID:11606584), (PMID:9697839) RGD PMID:9697839 PMID:11606584 NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:239,753,648...239,821,113 		JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,227,251...30,290,015
Ensembl chr  X:30,227,251...30,289,993 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO
IEA
IBA 		(PMID:15509800)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15509800 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:23499492)
(PMID:9254656) 		GO_Central
RGD		 PMID:9254656 PMID:23499492 GO_REF:0000033 NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Cd38 CD38 molecule involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd79a CD79a molecule involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:1439759), (PMID:8626447)
(PMID:1373499), (PMID:8626447) 		GO_Central
Ensembl
RGD		 PMID:1373499 PMID:1439759 PMID:8626447 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:89,621,460...89,625,813
Ensembl chr 1:80,493,581...80,497,935 		JBrowse link
G Cd79b CD79b molecule involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:8626447)
(PMID:1373499), (PMID:8626447) 		GO_Central
RGD		 PMID:1373499 PMID:8626447 GO_REF:0000033 NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,239,356...91,242,625 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IEA
IBA 		(PMID:17875758)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:17875758 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Fcrl5 Fc receptor-like 5 acts_upstream_of ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9199344) 		Ensembl
RGD		 PMID:9199344 GO_REF:0000107 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:8976175) RGD PMID:8976175
G Itk IL2-inducible T-cell kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:31,254,667...31,316,004
Ensembl chr10:30,753,344...30,814,685 		JBrowse link
G Klhl6 kelch-like family member 6 involved_in ISO
IEA 		(PMID:16166635)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:16166635 GO_REF:0000002 GO_REF:0000107 NCBI chr11:80,970,917...81,010,593
Ensembl chr11:80,970,917...81,009,677 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 involved_in ISO
IEA
IBA 		(PMID:12514734)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12514734 GO_REF:0000033 GO_REF:0000107 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:7499277) 		GO_Central
RGD		 PMID:7499277 GO_REF:0000033 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:16249387) 		GO_Central
Ensembl
InterPro
RGD		 PMID:16249387 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO
IEA 		MGI:3053558 (PMID:23509253), (PMID:7499277)
GO_REF:0000107 		RGD
Ensembl		 PMID:7499277 PMID:23509253 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:9254656)
GO_REF:0000107 		RGD
Ensembl		 PMID:9254656 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO 		GO_REF:0000024
(PMID:18955699) 		UniProt
RGD		 PMID:18955699 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 involved_in ISO
IEA 		(PMID:18474602)
GO_REF:0000107 		RGD
Ensembl		 PMID:18474602 GO_REF:0000107 NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:207,906,374...207,918,512 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO 		GO_REF:0000024
(PMID:17875758) 		UniProt
RGD		 PMID:17875758 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15143214) 		GO_Central
RGD		 PMID:15143214 GO_REF:0000033 NCBI chr 7:116,019,383...116,055,628
Ensembl chr 7:114,139,345...114,175,442 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17367755) 		Ensembl
RGD		 PMID:17367755 GO_REF:0000107 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:17367755) RGD PMID:17367755 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:17367755) RGD PMID:17367755 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO (PMID:11606584), (PMID:15509800)
(PMID:10925250) 		RGD PMID:10925250 PMID:11606584 PMID:15509800 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in ISO
IEA 		(PMID:12101241)
GO_REF:0000107 		RGD
Ensembl		 PMID:12101241 GO_REF:0000107 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156 		JBrowse link
G Prkcb protein kinase C, beta involved_in ISS
ISO 		GO_REF:0000024
(PMID:12118249) 		UniProt
RGD		 PMID:12118249 GO_REF:0000024 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within ISO
IEA 		MGI:1856074|MGI:3053558 (PMID:23509253), (PMID:9254656)
GO_REF:0000107 		RGD
Ensembl		 PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
(PMID:8692271)
MGI:2181288 (PMID:7499277), (PMID:9254656) 		UniProt
RGD		 PMID:7499277 PMID:8692271 PMID:9254656 GO_REF:0000024 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (PMID:12805216) RGD PMID:12805216 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:9233773)
GO_REF:0000107
(PMID:10872802) 		RGD
Ensembl		 PMID:9233773 PMID:10872802 GO_REF:0000107 NCBI chr12:26,063,812...26,093,468
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO
IEA 		MGI:98355 (PMID:24043312)
GO_REF:0000107 		RGD
Ensembl		 PMID:24043312 GO_REF:0000107 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:9199344)
(PMID:7499277), (PMID:8626447)
GO_REF:0000033
(PMID:15509800) 		UniProt
Ensembl
RGD
GO_Central		 PMID:7499277 PMID:8626447 PMID:9199344 PMID:15509800 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tec tec protein tyrosine kinase involved_in ISO
IEA
IBA 		(PMID:10518561)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:10518561 GO_REF:0000033 GO_REF:0000107 NCBI chr14:35,706,557...35,815,563
Ensembl chr14:35,352,829...35,461,557 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:197,011,831...197,354,321 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) RGD PMID:15294986 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:12719478)
GO_REF:0000107
(PMID:19358895) 		RGD
Ensembl		 PMID:12719478 PMID:19358895 GO_REF:0000107 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Fcna ficolin A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105 		JBrowse link
G Fcnb ficolin B involved_in ISO
IEA 		(PMID:21037097)
GO_REF:0000107 		RGD
Ensembl		 PMID:21037097 GO_REF:0000107 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO
IEA
ISS 		(PMID:21037097)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21037097 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA 		(PMID:15294986)
GO_REF:0000107 		RGD
Ensembl		 PMID:15294986 GO_REF:0000107 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) RGD PMID:22966085 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA 		(PMID:19358895)
GO_REF:0000107 		RGD
Ensembl		 PMID:19358895 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (PMID:12719478) RGD PMID:12719478 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blvra biliverdin reductase A acts_upstream_of_or_within ISO (PMID:30952817) RGD PMID:30952817 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) RGD PMID:10571060 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:19162005) RGD PMID:19162005 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G C3 complement C3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22632727) 		Ensembl
RGD		 PMID:22632727 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:10571060) 		Ensembl
GO_Central
RGD		 PMID:10571060 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA
IBA 		GO_REF:0000108
GO_REF:0000033 		GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:48,634,929...48,687,833
Ensembl chr12:42,974,410...43,028,129 		JBrowse link
G Cr2 complement C3d receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:109,207,034...109,244,980
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G Fpr1 formyl peptide receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:58,747,246...58,756,559 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Fpr2l1 formyl peptide receptor 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:68,359,518...68,360,549
Ensembl chr 1:59,686,103...59,716,622 		JBrowse link
G Fpr2l2 formyl peptide receptor 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:67,670,128...67,671,099
Ensembl chr 1:58,968,268...58,999,984 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15907827), (PMID:19135435) 		UniProt
Ensembl
RGD		 PMID:15907827 PMID:19135435 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Gpr33-ps1 G protein-coupled receptor 33, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:69,474,435...69,475,440
Ensembl chr 6:69,474,435...69,475,440 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) RGD PMID:22632727 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) RGD PMID:19162005 NCBI chr15:61,071,574...61,084,408
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:14764707) 		GO_Central
RGD		 PMID:14764707 GO_REF:0000033 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:16272347)
GO_REF:0000033 		UniProt
Ensembl
RGD
GO_Central		 PMID:16272347 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc epsilon receptor II involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Myo1g myosin IG involved_in ISO
IEA 		(PMID:23038771)
GO_REF:0000107 		RGD
Ensembl		 PMID:23038771 GO_REF:0000107 NCBI chr14:81,386,701...81,401,843
Ensembl chr14:81,386,701...81,401,843 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) RGD PMID:19265123 NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO
IEA
IBA 		(PMID:24169826), (PMID:26017478)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:24169826 PMID:26017478 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:21482706) RGD PMID:21482706 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd72 Cd72 molecule involved_in ISO
IEA 		(PMID:1711157)
GO_REF:0000107 		RGD
Ensembl		 PMID:1711157 GO_REF:0000107 NCBI chr 5:62,493,155...62,500,779
Ensembl chr 5:57,697,367...57,704,725 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcrl5 Fc receptor-like 5 acts_upstream_of_or_within ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:55,136,043...55,139,106
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Lpxn leupaxin involved_in ISO
IEA
IBA 		(PMID:17640867)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:17640867 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084 		JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO
IEA 		MGI:2679632 (PMID:14517301)
GO_REF:0000107 		RGD
Ensembl		 PMID:14517301 GO_REF:0000107 NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,292,695...3,477,009 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA 		(PMID:35941532)
GO_REF:0000107 		RGD
Ensembl		 PMID:35941532 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:25568335) RGD PMID:25568335 NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO
IEA 		(PMID:23589618)
GO_REF:0000107 		RGD
Ensembl		 PMID:23589618 GO_REF:0000107 NCBI chr17:42,048,842...42,060,650
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Btnl2 butyrophilin-like 2 acts_upstream_of_or_within ISO (PMID:16751379) RGD PMID:16751379 NCBI chr20:4,490,169...4,504,002
Ensembl chr20:4,489,517...4,503,341 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO
IEA 		(PMID:38225265)
GO_REF:0000107 		RGD
Ensembl		 PMID:38225265 GO_REF:0000107 NCBI chr 1:254,159,085...254,324,819
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO
IEA 		MGI:2180572 (PMID:14738763)
GO_REF:0000107 		RGD
Ensembl		 PMID:14738763 GO_REF:0000107 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cd160 CD160 molecule involved_in ISO
IEA 		(PMID:18193050)
GO_REF:0000107 		RGD
Ensembl		 PMID:18193050 GO_REF:0000107 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS 		(PMID:18424730)
GO_REF:0000024 		RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Csk C-terminal Src kinase involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISS
ISO 		GO_REF:0000024
(PMID:12883552) 		UniProt
RGD		 PMID:12883552 GO_REF:0000024 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in 		ISO (PMID:24714587)
(PMID:38225265) 		RGD PMID:24714587 PMID:38225265 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO
IBA 		(PMID:12447358)
GO_REF:0000033 		RGD
GO_Central		 PMID:12447358 GO_REF:0000033 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO
IEA 		MGI:1926074 (PMID:14738763)
GO_REF:0000107 		RGD
Ensembl		 PMID:14738763 GO_REF:0000107 NCBI chr15:61,354,026...61,395,762
Ensembl chr15:54,865,616...54,986,699 		JBrowse link
G Ezr ezrin involved_in ISO
IEA 		(PMID:20551903)
GO_REF:0000107 		RGD
Ensembl		 PMID:20551903 GO_REF:0000107 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Itpripl1 ITPRIP like 1 involved_in ISO (PMID:38614099) RGD PMID:38614099 NCBI chr 3:134,858,316...134,861,241
Ensembl chr 3:114,402,270...114,414,497 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:19706535) RGD PMID:19706535 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035), (PMID:22387553) RGD PMID:16493035 PMID:22387553 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA 		(PMID:38614099)
GO_REF:0000107 		RGD
Ensembl		 PMID:38614099 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (PMID:12970181) RGD PMID:12970181 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) RGD PMID:18796614 NCBI chr 3:8,392,926...8,394,325 JBrowse link
G Prnp prion protein involved_in ISO
IEA 		(PMID:20145049)
GO_REF:0000107 		RGD
Ensembl		 PMID:20145049 GO_REF:0000107 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:22080863)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:22080863 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:18056643) RGD PMID:18056643 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within ISO
IEA 		MGI:1856074 (PMID:9064344)
GO_REF:0000107 		RGD
Ensembl		 PMID:9064344 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA 		(PMID:11259588), (PMID:12913111), (PMID:9780142)
GO_REF:0000107
(PMID:12913111) 		RGD
Ensembl		 PMID:9780142 PMID:11259588 PMID:12913111 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO
IEA
IBA 		(PMID:26755705)
GO_REF:0000002
GO_REF:0000033 		RGD
InterPro
GO_Central		 PMID:26755705 GO_REF:0000002 GO_REF:0000033 NCBI chr12:17,363,721...17,365,577
Ensembl chr12:17,364,080...17,365,280 		JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO
IEA 		(PMID:9774102)
GO_REF:0000107 		RGD
Ensembl		 PMID:9774102 GO_REF:0000107 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sla2 Src-like-adaptor 2 involved_in ISO
IEA 		(PMID:11891219)
GO_REF:0000107 		RGD
Ensembl		 PMID:11891219 GO_REF:0000107 NCBI chr 3:145,367,070...145,383,586
Ensembl chr 3:145,368,598...145,382,480 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISS
ISO 		GO_REF:0000024
(PMID:9285719) 		UniProt
RGD		 PMID:9285719 GO_REF:0000024 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:107180 (PMID:14738763) 		GO_Central
RGD		 PMID:14738763 GO_REF:0000033 NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:20385881) 		UniProt
Ensembl
RGD		 PMID:20385881 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA 		(PMID:26599367)
GO_REF:0000107 		RGD
Ensembl		 PMID:26599367 GO_REF:0000107 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA 		ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107 		RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) RGD PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IBA
IEA 		(PMID:21900486)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:21900486 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19948740) 		UniProt
Ensembl
RGD		 PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:20385881) 		UniProt
Ensembl
RGD		 PMID:20385881 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA 		(PMID:28609714)
GO_REF:0000107 		RGD
Ensembl		 PMID:28609714 GO_REF:0000107 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA 		(PMID:18511497)
GO_REF:0000107 		RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO
IEA 		(PMID:17395780)
GO_REF:0000107 		RGD
Ensembl		 PMID:17395780 GO_REF:0000107 NCBI chr13:45,673,396...45,699,798
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
IEA 		(PMID:31281713)
GO_REF:0000107 		RGD
Ensembl		 PMID:31281713 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO
IEA 		(PMID:28898289)
GO_REF:0000107 		RGD
Ensembl		 PMID:28898289 GO_REF:0000107 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460), (PMID:31134514) RGD PMID:29407460 PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA 		(PMID:19912257)
GO_REF:0000107 		RGD
Ensembl		 PMID:19912257 GO_REF:0000107 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir210 microRNA 210 involved_in ISO (PMID:38742642) RGD PMID:38742642 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO 		GO_REF:0000024
(PMID:8692271) 		UniProt
RGD		 PMID:8692271 GO_REF:0000024 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO 		GO_REF:0000024
(PMID:23499492)
(PMID:20237408) 		UniProt
RGD		 PMID:20237408 PMID:23499492 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO
IEA 		(PMID:15196959)
GO_REF:0000107 		RGD
Ensembl		 PMID:15196959 GO_REF:0000107 NCBI chr19:629,000...637,152
Ensembl chr19:604,458...629,790 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO
IEA 		(PMID:30111844)
GO_REF:0000107 		RGD
Ensembl		 PMID:30111844 GO_REF:0000107 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr15:98,587,984...98,588,079
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:24169826), (PMID:26017478) RGD PMID:24169826 PMID:26017478 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:116,019,383...116,055,628
Ensembl chr 7:114,139,345...114,175,442 		JBrowse link
G Prkch protein kinase C, eta involved_in ISO
IEA
ISS 		(PMID:18780722)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:18780722 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO
IEA 		MGI:5642299 (PMID:25074919)
GO_REF:0000107 		RGD
Ensembl		 PMID:25074919 GO_REF:0000107 NCBI chr 9:62,331,281...62,454,754
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO
IBA 		(PMID:10518561)
GO_REF:0000033 		RGD
GO_Central		 PMID:10518561 GO_REF:0000033 NCBI chr14:22,301,278...22,336,218
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IEA
IBA 		(PMID:16831868)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16831868 GO_REF:0000033 GO_REF:0000107 NCBI chr18:84,723,330...84,819,836
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:Q64455 (PMID:18249142) RGD PMID:18249142 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA 		UniProtKB:P06800 (PMID:18249142)
GO_REF:0000107 		RGD
Ensembl		 PMID:18249142 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IMP RGD PMID:18832707 RGD:9835043 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:18832707 RGD:9835043 NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO
IEA 		(PMID:25568335)
GO_REF:0000107 		RGD
Ensembl		 PMID:25568335 GO_REF:0000107 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:24586680) 		UniProt
RGD		 PMID:24586680 GO_REF:0000024 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO
IEA 		MGI:1857117|MGI:2683027 (PMID:11435465)
GO_REF:0000107 		RGD
Ensembl		 PMID:11435465 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18287044), (PMID:27777308) 		UniProt
Ensembl
RGD		 PMID:18287044 PMID:27777308 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Card11 caspase recruitment domain family, member 11 involved_in ISO
IEA
IBA 		(PMID:12154360)
GO_REF:0000107
GO_REF:0000033
(PMID:12154356) 		RGD
Ensembl
GO_Central		 PMID:12154356 PMID:12154360 GO_REF:0000033 GO_REF:0000107 NCBI chr12:18,735,088...18,872,045
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO
IEA 		(PMID:17785582)
GO_REF:0000107 		RGD
Ensembl		 PMID:17785582 GO_REF:0000107 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Cd226 CD226 molecule involved_in ISO
IEA
IBA 		(PMID:26755705)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:26755705 GO_REF:0000033 GO_REF:0000107 NCBI chr18:84,723,330...84,819,836
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO
ISS 		(PMID:23858057)
GO_REF:0000024 		RGD
UniProt		 PMID:23858057 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO
IEA 		MGI:3664438 (PMID:16501569)
GO_REF:0000107 		RGD
Ensembl		 PMID:16501569 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISS
ISO 		GO_REF:0000024
(PMID:18287044), (PMID:27777308) 		UniProt
RGD		 PMID:18287044 PMID:27777308 GO_REF:0000024 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO
IEA 		(PMID:18796614)
GO_REF:0000107 		RGD
Ensembl		 PMID:18796614 GO_REF:0000107 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO
IEA 		MGI:2451080 (PMID:19179613)
GO_REF:0000107 		RGD
Ensembl		 PMID:19179613 GO_REF:0000107 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IEA
IBA 		(PMID:26755705)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:26755705 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:20819079) 		UniProt
Ensembl
RGD		 PMID:20819079 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO
IEA 		(PMID:26021297)
GO_REF:0000107 		RGD
Ensembl		 PMID:26021297 GO_REF:0000107 NCBI chr13:45,859,930...45,865,468
Ensembl chr13:43,307,775...43,313,417 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA 		(PMID:18045535)
GO_REF:0000107 		RGD
Ensembl		 PMID:18045535 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Taok3 TAO kinase 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:11390434)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:11390434 GO_REF:0000033 GO_REF:0000107 NCBI chr11:65,498,742...65,540,823
Ensembl chr11:52,035,750...52,077,805 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO
IEA 		(PMID:38225265)
GO_REF:0000107 		RGD
Ensembl		 PMID:38225265 GO_REF:0000107 NCBI chr 9:21,480,058...21,559,936
Ensembl chr 9:13,982,329...14,062,139 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA 		(PMID:22423966)
GO_REF:0000107 		RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:19865078)
GO_REF:0000107 		RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA 		(PMID:26599367), (PMID:28471450)
GO_REF:0000107 		RGD
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
IEA
ISS 		(PMID:28471450)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:28471450 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr1 toll-like receptor 1 involved_in ISO
IEA 		ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107 		RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:24380872) 		UniProt
Ensembl
RGD		 PMID:24380872 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA 		(PMID:18622013)
GO_REF:0000107 		RGD
Ensembl		 PMID:18622013 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO
IEA 		(PMID:29038465)
GO_REF:0000107 		RGD
Ensembl		 PMID:29038465 GO_REF:0000107 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA 		(PMID:11528597)
GO_REF:0000107 		RGD
Ensembl		 PMID:11528597 GO_REF:0000107 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:25860173) 		UniProt
RGD		 PMID:25860173 GO_REF:0000024 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA 		(PMID:18511497)
GO_REF:0000107 		RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA 		MGI:4361448 (PMID:19734906)
GO_REF:0000107 		RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567) 		RGD PMID:19412184 PMID:22685567 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA 		(PMID:25736436)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO
IEA 		(PMID:28593998)
GO_REF:0000107 		RGD
Ensembl		 PMID:28593998 GO_REF:0000107 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO
IEA 		(PMID:9382888)
GO_REF:0000107 		RGD
Ensembl		 PMID:9382888 GO_REF:0000107 NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Fcmr Fc mu receptor involved_in ISS
ISO 		GO_REF:0000024
(PMID:28135254) 		UniProt
RGD		 PMID:28135254 GO_REF:0000024 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Gcsam germinal center-associated, signaling and motility involved_in ISO
IEA
IBA 		(PMID:23299888)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:23299888 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr11:55,195,757...55,207,011
Ensembl chr11:55,196,712...55,206,992 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:11672542)
GO_REF:0000033 		UniProt
Ensembl
RGD
GO_Central		 PMID:11672542 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd47 Cd47 molecule involved_in IMP PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Csk C-terminal Src kinase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:9325302 GO_REF:0000033, RGD:2303720 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:22184119 PMID:16482158 RGD:11041001, RGD:2293335 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in IMP PMID:18579528 UniProt PMID:18579528 RGD:2303650 NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Pten phosphatase and tensin homolog IMP negative regulation RGD PMID:18056380 RGD:2292524 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO
IEA 		(PMID:15235600), (PMID:17341663)
GO_REF:0000107 		RGD
Ensembl		 PMID:15235600 PMID:17341663 GO_REF:0000107 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10, immune signaling adaptor acts_upstream_of_or_within ISO
IEA 		MGI:2158304 (PMID:14614861)
GO_REF:0000107 		RGD
Ensembl		 PMID:14614861 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:22046970) RGD PMID:22046970 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) RGD PMID:14752163 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO
IEA 		MGI:3639305 (PMID:14614861)
GO_REF:0000107 		RGD
Ensembl		 PMID:14614861 GO_REF:0000107 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P05480 (PMID:15661907) RGD PMID:15661907 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO
IEA 		(PMID:15917799)
GO_REF:0000107 		RGD
Ensembl		 PMID:15917799 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:27219021) RGD PMID:27219021 NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO
IEA 		(PMID:27219021)
GO_REF:0000107 		RGD
Ensembl		 PMID:27219021 GO_REF:0000107 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:19289601) RGD PMID:19289601 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) RGD PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4a C-type lectin domain family 4, member A involved_in ISO (PMID:22041900) RGD PMID:22041900 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402 		JBrowse link
G Clec6a-ps1 C-type lectin domain family 6, member A, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19136564) RGD PMID:19136564 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,828,163...164,838,446
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9655483) RGD PMID:9655483 NCBI chr 4:164,808,722...164,819,865
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
IEA
ISS 		(PMID:9655483)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
GO_Central
Ensembl
UniProt		 PMID:9655483 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Klre1 killer cell lectin like receptor E1 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_REF:0000033
GO_REF:0000107 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535 		JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870 		JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO (PMID:19136564), (PMID:22041900) RGD PMID:19136564 PMID:22041900 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:19136564) 		Ensembl
RGD		 PMID:19136564 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IEA
ISS 		(PMID:9655483)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:9655483 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:9655483) 		UniProt
Ensembl
RGD		 PMID:9655483 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07044388.4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:4,338,257...4,339,485 JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO
IEA 		(PMID:18305217)
GO_REF:0000107 		RGD
Ensembl		 PMID:18305217 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Ada adenosine deaminase acts_upstream_of ISO
IEA 		MGI:1857117|MGI:2683027 (PMID:11435465)
GO_REF:0000107 		RGD
Ensembl		 PMID:11435465 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15125833) 		UniProt
Ensembl
RGD		 PMID:15125833 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) RGD PMID:18228248 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btk Bruton tyrosine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,653,499...41,664,246
Ensembl chr17:41,654,249...41,664,272 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,048,842...42,060,650
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Btn3a2 butyrophilin, subfamily 3, member A2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,398,254...4,405,681
Ensembl chr20:4,398,254...4,405,681 		JBrowse link
G Btnl10 butyrophilin like 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:43,694,083...43,701,800
Ensembl chr10:43,694,073...43,700,926 		JBrowse link
G Btnl12 butyrophilin-like 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:62,863,239...62,879,705
Ensembl chr11:62,869,439...62,879,796 		JBrowse link
G Btnl2 butyrophilin-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,490,169...4,504,002
Ensembl chr20:4,489,517...4,503,341 		JBrowse link
G Btnl3 butyrophilin-like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,475,984...4,490,955
Ensembl chr20:4,474,056...4,489,024 		JBrowse link
G Btnl4 butyrophilin-like 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,231,350...4,244,825
Ensembl chr20:4,235,141...4,244,690 		JBrowse link
G Btnl5 butyrophilin-like 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385 		JBrowse link
G Btnl7 butyrophilin-like 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,301,078...4,313,522
Ensembl chr20:4,301,854...4,313,274 		JBrowse link
G Btnl8 butyrophilin-like 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,264,840...4,280,876
Ensembl chr20:4,266,794...4,408,167
Ensembl chr20:4,266,794...4,408,167 		JBrowse link
G Btnl9 butyrophilin-like 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO
IEA 		MGI:2389248 (PMID:17028169)
GO_REF:0000107 		RGD
Ensembl		 PMID:17028169 GO_REF:0000107 NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO
IEA 		MGI:1856936 (PMID:17028169)
GO_REF:0000107 		RGD
Ensembl		 PMID:17028169 GO_REF:0000107 NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO MGI:5547539 (PMID:23793062) RGD PMID:23793062 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO
IEA 		(PMID:12697763)
GO_REF:0000107 		RGD
Ensembl		 PMID:12697763 GO_REF:0000107 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cd247 Cd247 molecule acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:11435465)
GO_REF:0000107
GO_REF:0000033
(PMID:35271814) 		RGD
Ensembl
GO_Central		 PMID:11435465 PMID:35271814 GO_REF:0000033 GO_REF:0000107 NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd276 Cd276 molecule involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd28 Cd28 molecule involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:1857150 (PMID:23793062) 		GO_Central
RGD		 PMID:23793062 GO_REF:0000033 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd2ap CD2-associated protein acts_upstream_of_or_within ISO MGI:2664945 (PMID:14512504) RGD PMID:14512504 NCBI chr 9:25,580,071...25,679,968
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within
involved_in 		ISO (PMID:10485657)
(PMID:38614099) 		RGD PMID:10485657 PMID:38614099 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd8a CD8 subunit alpha involved_in ISO (PMID:17145893) RGD PMID:17145893 NCBI chr 4:104,924,116...104,928,353
Ensembl chr 4:103,365,804...103,370,040 		JBrowse link
G Cd8b CD8 subunit beta involved_in ISO (PMID:17145893) RGD PMID:17145893 NCBI chr 4:104,870,911...104,886,838
Ensembl chr 4:103,312,578...103,328,553 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (PMID:18305217) RGD PMID:18305217 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO
IEA
IBA 		(PMID:26774822)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:26774822 GO_REF:0000033 GO_REF:0000107 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO
IEA
ISS 		(PMID:8626696)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:8626696) 		Ensembl
UniProt
RGD		 PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO
IEA
ISS 		(PMID:8626696)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:130,492,167...130,558,692
Ensembl chr 5:130,492,220...130,563,332 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:8626696) 		UniProt
Ensembl
RGD		 PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:8626696) 		UniProt
Ensembl
RGD		 PMID:8626696 GO_REF:0000024 GO_REF:0000107 NCBI chr11:93,898,814...93,909,431
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G ENSRNOG00000063827 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 5:126,991,244...127,118,584 JBrowse link
G ENSRNOG00000067562 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 5:127,293,600...127,420,989 JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in ISO
IEA 		(PMID:32098969)
GO_REF:0000107 		RGD
Ensembl		 PMID:32098969 GO_REF:0000107 NCBI chr16:18,447,424...18,464,738
Ensembl chr16:18,413,363...18,435,104 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO
IEA 		(PMID:32610127)
GO_REF:0000107 		RGD
Ensembl		 PMID:32610127 GO_REF:0000107 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO
IEA 		MGI:1857034 (PMID:10072494), (PMID:11265635)
GO_REF:0000107 		RGD
Ensembl		 PMID:10072494 PMID:11265635 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Fyb1 FYN binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629 		JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO
IEA
IBA 		(PMID:27335501)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:27335501 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:119,677,116...119,800,911
Ensembl chr 5:119,677,204...119,800,910 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IBA
IEA 		(PMID:7722293)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:7722293 GO_REF:0000033 GO_REF:0000107 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO
IEA 		(PMID:20696860)
GO_REF:0000107 		RGD
Ensembl		 PMID:20696860 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:2385945 (PMID:21444916) RGD PMID:21444916 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Icoslg inducible T-cell co-stimulator ligand involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,420...10,610,703 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) RGD PMID:21444916 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Itk IL2-inducible T-cell kinase involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:10213685) 		GO_Central
Ensembl
RGD		 PMID:10213685 GO_REF:0000033 GO_REF:0000107 NCBI chr10:31,254,667...31,316,004
Ensembl chr10:30,753,344...30,814,685 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in ISO
IEA 		(PMID:9045636)
GO_REF:0000107 		RGD
Ensembl		 PMID:9045636 GO_REF:0000107 NCBI chr 5:147,337,048...147,374,604
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Lat linker for activation of T cells involved_in ISO (PMID:11368773), (PMID:25907557) RGD PMID:11368773 PMID:25907557 NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:38614099), (PMID:8943371) RGD PMID:8943371 PMID:38614099 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO
IEA 		(PMID:20551903)
GO_REF:0000107 		RGD
Ensembl		 PMID:20551903 GO_REF:0000107 NCBI chr10:19,146,846...19,193,750
Ensembl chr10:18,642,658...18,689,559 		JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO
IEA
IBA 		(PMID:15125833)
GO_REF:0000107
(PMID:25282160)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15125833 PMID:25282160 GO_REF:0000033 GO_REF:0000107 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:9064344)
GO_REF:0000107 		RGD
Ensembl		 PMID:9064344 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:2385944 (PMID:21444916) RGD PMID:21444916 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO
IEA 		(PMID:17404263)
GO_REF:0000107 		RGD
Ensembl		 PMID:17404263 GO_REF:0000107 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in ISO
IEA 		(PMID:17404263)
GO_REF:0000107 		RGD
Ensembl		 PMID:17404263 GO_REF:0000107 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Plcg1 phospholipase C, gamma 1 acts_upstream_of_or_within ISO (PMID:15728238) RGD PMID:15728238 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:15728238) RGD PMID:15728238 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISO
IEA 		(PMID:17077180)
GO_REF:0000107 		RGD
Ensembl		 PMID:17077180 GO_REF:0000107 NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO
IEA 		MGI:109284 (PMID:17698590)
GO_REF:0000107 		RGD
Ensembl		 PMID:17698590 GO_REF:0000107 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:17698590) RGD PMID:17698590 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3043469 (PMID:14752163) 		GO_Central
RGD		 PMID:14752163 GO_REF:0000033 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of ISO
IEA 		MGI:1856074 (PMID:9064344)
GO_REF:0000107 		RGD
Ensembl		 PMID:9064344 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in IGI
IEA
ISO
ISS 		PMID:12496963
GO_REF:0000107
UniProtKB:P04157 (PMID:12496963)
GO_REF:0000002
GO_REF:0000024
(PMID:10358156) 		Ensembl
RGD
InterPro
UniProt		 PMID:10358156 PMID:12496963 PMID:12496963 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:1358565 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO
IEA 		(PMID:20005846)
GO_REF:0000107 		RGD
Ensembl		 PMID:20005846 GO_REF:0000107 NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO
IEA 		(PMID:25282160)
GO_REF:0000107 		RGD
Ensembl		 PMID:25282160 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:21,110,679...21,179,933 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (PMID:19414744) RGD PMID:19414744 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:2660793 (PMID:11894098)
GO_REF:0000107
(PMID:21469090) 		RGD
Ensembl		 PMID:11894098 PMID:21469090 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO
IEA 		(PMID:20005846)
GO_REF:0000107 		RGD
Ensembl		 PMID:20005846 GO_REF:0000107 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915 		JBrowse link
G RT1-Bb RT1 class II, locus Bb involved_in ISO (PMID:32341563) RGD PMID:32341563 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:10435578) RGD PMID:10435578 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:32341563) RGD PMID:32341563 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 involved_in ISO
IEA 		(PMID:32341563)
GO_REF:0000107 		RGD
Ensembl		 PMID:32341563 GO_REF:0000107 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO
IEA 		MGI:3721903 (PMID:24645804)
GO_REF:0000107 		RGD
Ensembl		 PMID:24645804 GO_REF:0000107 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:59,678,216...59,785,538 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:16491128) RGD PMID:16491128 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO
IEA 		(PMID:11909961)
GO_REF:0000107 		RGD
Ensembl		 PMID:11909961 GO_REF:0000107 NCBI chr10:81,425,472...81,732,651
Ensembl chr10:81,425,525...81,732,650 		JBrowse link
G Skint1 selection and upkeep of intraepithelial T cells 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:126,786,469...126,814,599
Ensembl chr 5:126,786,469...126,814,720 		JBrowse link
G Skint10 selection and upkeep of intraepithelial T cells 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:127,769,022...127,811,541
Ensembl chr 5:127,769,052...127,847,189 		JBrowse link
G Skint2 selection and upkeep of intraepithelial T cells 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:126,878,834...126,909,044
Ensembl chr 5:126,875,682...126,913,167 		JBrowse link
G Skint8 selection and upkeep of intraepithelial T cells 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:126,764,502...126,773,125
Ensembl chr 5:126,751,394...126,773,247 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:34394081) 		UniProt
Ensembl
RGD		 PMID:34394081 GO_REF:0000024 GO_REF:0000107 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417 		JBrowse link
G Spn sialophorin involved_in IGI PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971) RGD PMID:25384971 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO MGI:2387402|MGI:3054844|MGI:96756 (PMID:21487392) RGD PMID:21487392 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stoml2 stomatin like 2 acts_upstream_of_or_within ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18641330) 		UniProt
Ensembl
RGD		 PMID:18641330 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:62,052,042...62,055,639
Ensembl chr 5:57,256,220...57,259,920 		JBrowse link
G Tec tec protein tyrosine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:35,706,557...35,815,563
Ensembl chr14:35,352,829...35,461,557 		JBrowse link
G Themis thymocyte selection associated involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:19597498), (PMID:19597499) 		GO_Central
Ensembl
RGD		 PMID:19597498 PMID:19597499 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:18,251,136...18,483,851
Ensembl chr 1:16,432,631...16,664,329 		JBrowse link
G Themis2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:22732588) 		GO_Central
Ensembl
RGD		 PMID:22732588 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400 		JBrowse link
G Themis3 thymocyte selection associated family member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:106,543,112...106,580,780
Ensembl chr 9:106,543,723...106,580,907 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IMP PMID:9285719 UniProt PMID:9285719 RGD:8554466 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:11485735) 		UniProt
Ensembl
RGD		 PMID:11485735 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833), (PMID:23514740) RGD PMID:15125833 PMID:23514740 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Txk TXK tyrosine kinase involved_in IBA
ISO 		GO_REF:0000033
(PMID:10213685) 		GO_Central
RGD		 PMID:10213685 GO_REF:0000033 NCBI chr14:35,817,270...35,873,454
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:15125833) RGD PMID:15125833 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27400149) 		Ensembl
RGD		 PMID:27400149 GO_REF:0000107 NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:3526403 (PMID:9208839)
GO_REF:0000107
(PMID:38614099), (PMID:9489702) 		RGD
Ensembl		 PMID:9208839 PMID:9489702 PMID:38614099 GO_REF:0000107 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:23185455), (PMID:25282160) 		UniProt
Ensembl
RGD		 PMID:23185455 PMID:25282160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:26179882) RGD PMID:26179882 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:146,278,978...146,285,000 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:10383454)
GO_REF:0000107
GO_REF:0000033
(PMID:10549626) 		RGD
Ensembl
GO_Central		 PMID:10383454 PMID:10549626 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA 		(PMID:22187460)
GO_REF:0000107 		RGD
Ensembl		 PMID:22187460 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA 		(PMID:11894098)
GO_REF:0000107 		RGD
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:16633345) 		GO_Central
Ensembl
RGD		 PMID:16633345 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO
IBA 		(PMID:27986454)
GO_REF:0000033 		RGD
GO_Central		 PMID:27986454 GO_REF:0000033 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO
IEA 		(PMID:26189595)
GO_REF:0000107 		RGD
Ensembl		 PMID:26189595 GO_REF:0000107 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ecsit ECSIT signaling integrator involved_in ISO
IEA 		(PMID:25371197)
GO_REF:0000107 		RGD
Ensembl		 PMID:25371197 GO_REF:0000107 NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:20,605,583...20,618,390 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 acts_upstream_of_or_within
involved_in 		ISO
IBA 		(PMID:10549626)
GO_REF:0000033 		RGD
GO_Central		 PMID:10549626 GO_REF:0000033 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in ISO
IEA 		(PMID:17878161)
GO_REF:0000107 		RGD
Ensembl		 PMID:17878161 GO_REF:0000107 NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO
IEA 		(PMID:25636800)
GO_REF:0000107 		RGD
Ensembl		 PMID:25636800 GO_REF:0000107 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Letmd1 LETM1 domain containing 1 acts_upstream_of_or_within ISO
IEA 		(PMID:31980577)
GO_REF:0000107 		RGD
Ensembl		 PMID:31980577 GO_REF:0000107 NCBI chr 7:133,461,920...133,476,592
Ensembl chr 7:131,584,259...131,597,796 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO
IBA 		(PMID:24380872)
GO_REF:0000033 		RGD
GO_Central		 PMID:24380872 GO_REF:0000033 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA 		(PMID:28098138)
GO_REF:0000107 		RGD
Ensembl		 PMID:28098138 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO
IEA 		(PMID:25371197)
GO_REF:0000107 		RGD
Ensembl		 PMID:25371197 GO_REF:0000107 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA
IBA 		(PMID:16751103)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16751103 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO
IEA 		MGI:1934018 (PMID:29624734)
GO_REF:0000107 		RGD
Ensembl		 PMID:29624734 GO_REF:0000107 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within 		ISO (PMID:7479976)
(PMID:18261938) 		RGD PMID:7479976 PMID:18261938 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA 		(PMID:22187458), (PMID:22187460)
GO_REF:0000107 		RGD
Ensembl		 PMID:22187458 PMID:22187460 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA 		(PMID:25355951)
GO_REF:0000107 		RGD
Ensembl		 PMID:25355951 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA 		MGI:2660793 (PMID:11894098)
GO_REF:0000107 		RGD
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G S100a14 S100 calcium binding protein A14 involved_in ISO
IEA 		(PMID:17625598)
GO_REF:0000107 		RGD
Ensembl		 PMID:17625598 GO_REF:0000107 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA 		(PMID:28747347)
GO_REF:0000107 		RGD
Ensembl		 PMID:28747347 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) RGD PMID:12471095 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:28630139) RGD PMID:28630139 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO
IBA 		(PMID:16751103)
(PMID:11526399)
GO_REF:0000033 		RGD
GO_Central		 PMID:11526399 PMID:16751103 GO_REF:0000033 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA 		GO_REF:0000107
(PMID:28098138)
(PMID:25549946)
GO_REF:0000033
(PMID:10196138), (PMID:15618008), (PMID:18222170) 		Ensembl
RGD
GO_Central		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 PMID:28098138 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmem126a transmembrane protein 126A acts_upstream_of_or_within ISO
IEA 		(PMID:25549946)
GO_REF:0000107 		RGD
Ensembl		 PMID:25549946 GO_REF:0000107 NCBI chr 1:144,424,481...144,430,730
Ensembl chr 1:144,422,703...144,430,628 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO
IEA 		(PMID:18222170)
GO_REF:0000107 		RGD
Ensembl		 PMID:18222170 GO_REF:0000107 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:25371197) RGD PMID:25371197 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IEA
IBA 		(PMID:19710467)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19710467 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA 		(PMID:16751103)
GO_REF:0000107 		RGD
Ensembl		 PMID:16751103 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) RGD PMID:12447442 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO (PMID:14625549), (PMID:17128265) RGD PMID:14625549 PMID:17128265 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkce protein kinase C, epsilon involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16757566)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16757566 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO
IEA 		(PMID:30883606)
GO_REF:0000107 		RGD
Ensembl		 PMID:30883606 GO_REF:0000107 NCBI chr 1:258,950,535...259,094,555
Ensembl chr 1:258,923,873...259,093,752 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184) 		RGD PMID:19412184 PMID:22685567 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3132
      activation of immune response 599
        immune response-activating signaling pathway 516
          immune response-activating cell surface receptor signaling pathway 310
            Fc receptor mediated stimulatory signaling pathway + 20
            antigen receptor-mediated signaling pathway + 195
            complement receptor mediated signaling pathway + 16
            innate immune response activating cell surface receptor signaling pathway + 92
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of immune system process 1746
          positive regulation of immune system process 1208
            positive regulation of immune response 834
              activation of immune response 599
                immune response-activating signaling pathway 516
                  immune response-activating cell surface receptor signaling pathway 310
                    Fc receptor mediated stimulatory signaling pathway + 20
                    antigen receptor-mediated signaling pathway + 195
                    complement receptor mediated signaling pathway + 16
                    innate immune response activating cell surface receptor signaling pathway + 92
paths to the root