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ONTOLOGY REPORT - ANNOTATIONS

Term:chondroitin sulfate proteoglycan biosynthetic process
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Accession:GO:0050650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
Synonyms:exact_synonym: chondroitin sulfate proteoglycan anabolism;   chondroitin sulfate proteoglycan biosynthesis;   chondroitin sulfate proteoglycan formation;   chondroitin sulfate proteoglycan synthesis;   chondroitin sulphate proteoglycan biosynthesis;   chondroitin sulphate proteoglycan biosynthetic process


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chondroitin sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat1 beta-1,3-glucuronyltransferase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395 		JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:26,167,174...26,250,153
Ensembl chr 9:26,167,174...26,250,153 		JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:25893793)
GO_REF:0000033
(PMID:21763480)		 RGD
GO_Central		 PMID:21763480 PMID:25893793 GO_REF:0000033 NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:11788602)
MGI:1927166 (PMID:21138417)		 RGD PMID:11788602 PMID:21138417 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839 		JBrowse link
G Cytl1 cytokine like 1 acts_upstream_of_or_within ISO (PMID:17644814) RGD PMID:17644814 NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886 		JBrowse link
G Eml3 EMAP like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:205,826,354...205,837,790
Ensembl chr 1:205,817,378...205,837,807 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (PMID:17644814) RGD PMID:17644814 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
IBA
ISS		 (PMID:24425863)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:24425863 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in ISO
ISS
IBA		 (PMID:17189265)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:17189265 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISO
ISS
IBA		 (PMID:17189265), (PMID:26027496)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:17189265 PMID:26027496 GO_REF:0000024 GO_REF:0000033 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07047835.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 5:48,925,362...48,927,475 JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321 		JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294 		JBrowse link
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:12761225)
MGI:2681120|MGI:5464019 (PMID:22952769), (PMID:22952873)
MGI:1926173|MGI:2681120 (PMID:17253960), (PMID:22952769)
GO_REF:0000033		 RGD
GO_Central		 PMID:12761225 PMID:17253960 PMID:22952769 PMID:22952873 GO_REF:0000033 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878 		JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11056388)
MGI:1926002 (PMID:10722746), (PMID:21138417)
GO_REF:0000107		 RGD
Ensembl		 PMID:10722746 PMID:11056388 PMID:21138417 GO_REF:0000107 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057 		JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019 		JBrowse link
G Chst3 carbohydrate sulfotransferase 3 acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IEA
ISS		 MGI:2176247 (PMID:11696535), (PMID:9597547)
(PMID:9597547)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
(PMID:15215498), (PMID:9883891)		 RGD
GO_Central
Ensembl
UniProt		 PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:16495484 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1600854 NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807 		JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in ISO
IBA		 (PMID:10781596)
GO_REF:0000033		 RGD
GO_Central		 PMID:10781596 GO_REF:0000033 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11514575)
MGI:106576 (PMID:22952769)
GO_REF:0000033		 RGD
GO_Central		 PMID:11514575 PMID:22952769 GO_REF:0000033 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601 		JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA
ISO		 GO_REF:0000033
MGI:106576 (PMID:17253960)		 GO_Central
RGD		 PMID:17253960 GO_REF:0000033 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA		 (PMID:11514575), (PMID:12163485)
MGI:1926002|MGI:4868209 (PMID:17145758), (PMID:25568321), (PMID:29287114)
GO_REF:0000033		 RGD
GO_Central		 PMID:11514575 PMID:12163485 PMID:17145758 PMID:25568321 PMID:29287114 GO_REF:0000033 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA
ISO		 GO_REF:0000033
(PMID:25568321)		 GO_Central
RGD		 PMID:25568321 GO_REF:0000033 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839 		JBrowse link
G Slc35b2 solute carrier family 35 member B2 involved_in ISO (PMID:35325049) RGD PMID:35325049 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234 		JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (PMID:17952091) RGD PMID:17952091 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:5544658|PMID:24161523)		 UniProt
RGD		 PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO (PMID:12163485) RGD PMID:12163485 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11448
      primary metabolic process 10014
        protein metabolic process 4597
          glycoprotein metabolic process 383
            proteoglycan metabolic process 91
              proteoglycan biosynthetic process 66
                chondroitin sulfate proteoglycan biosynthetic process 26
                  chondroitin sulfate biosynthetic process 19
                  chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11448
      organic substance metabolic process 10963
        organonitrogen compound metabolic process 5655
          protein metabolic process 4597
            glycoprotein metabolic process 383
              proteoglycan metabolic process 91
                chondroitin sulfate proteoglycan metabolic process 34
                  chondroitin sulfate proteoglycan biosynthetic process 26
                    chondroitin sulfate biosynthetic process 19
                    chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1
paths to the root