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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:proteoglycan biosynthetic process
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Accession:GO:0030166 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
Synonyms:exact_synonym: proteoglycan anabolism;   proteoglycan biosynthesis;   proteoglycan formation;   proteoglycan synthesis



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proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856465 (MGI:2664273|PMID:3070812)
Ensembl
RGD
PMID:3070812 GO_REF:0000107 MGI:2664273 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 involved_in ISO (PMID:29443383) RGD PMID:29443383 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:9,018,514...9,027,591
Ensembl chr17:9,018,935...9,027,573
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Cant1 calcium activated nucleotidase 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:22539336)
UniProt
RGD
PMID:22539336 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:41,092,805...41,122,737
Ensembl chr 9:41,092,808...41,122,503
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019
JBrowse link
G Chst8 carbohydrate sulfotransferase 8 involved_in
acts_upstream_of_or_within
ISO (PMID:10988300)
(MGI:1928003|PMID:10988300)
RGD PMID:10988300 MGI:1928003 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
JBrowse link
G Chst9 carbohydrate sulfotransferase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:4946896|PMID:21185280) RGD PMID:21185280 MGI:4946896 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fam20b FAM20B, glycosaminoglycan xylosylkinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:68,801,663...68,839,979
Ensembl chr13:68,801,669...68,839,915
JBrowse link
G Foxl1 forkhead box L1 acts_upstream_of_or_within ISO MGI:2178230 (MGI:2153304|PMID:11555641) RGD PMID:11555641 MGI:2153304 NCBI chr19:49,197,269...49,200,682
Ensembl chr19:49,197,400...49,198,425
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
(PMID:12746903), (PMID:9564845)
GO_REF:0000107
RGD
Ensembl
PMID:9564845 PMID:12746903 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IMP
ISS
ISO
GO_REF:0000024
(PMID:11087729)
UniProt
RGD
PMID:11087729 PMID:19001053 GO_REF:0000024, RGD:2313142 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 acts_upstream_of_or_within ISO MGI:3714171 (MGI:3713963|PMID:17517600) RGD PMID:17517600 MGI:3713963 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07047835.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 5:48,925,362...48,927,475 JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321
JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294
JBrowse link
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1926173|MGI:2681120 (MGI:5462286|PMID:22952769), (MGI:7266375|PMID:17253960)
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
(PMID:12761225)
RGD PMID:12761225 PMID:17253960 PMID:22952769 PMID:22952873 PMID:21873635 MGI:5462280 MGI:5462286 MGI:7266375, RGD:13792537 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:11056388)
GO_REF:0000107
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)
RGD
Ensembl
PMID:10722746 PMID:11056388 PMID:21138417 GO_REF:0000107 MGI:1354846 MGI:4941099 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019
JBrowse link
G Chst3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within
IDA
IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(MGI:1206144|PMID:9597547)
GO_REF:0000024
(PMID:15215498), (PMID:9883891)
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)
Ensembl
RGD
UniProt
PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:16495484 More... GO_REF:0000024 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:1600854, RGD:13792537 NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807
JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in IBA
ISO
PMID:21873635
(PMID:10781596)
RGD PMID:10781596 PMID:21873635 RGD:13792537 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:106576 (MGI:5462286|PMID:22952769)
PMID:21873635
(PMID:11514575)
RGD PMID:11514575 PMID:22952769 PMID:21873635 MGI:5462286, RGD:13792537 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in ISO
IBA
MGI:106576 (MGI:7266375|PMID:17253960)
PMID:21873635
RGD PMID:17253960 PMID:21873635 MGI:7266375, RGD:13792537 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA
(PMID:11514575), (PMID:12163485)
PMID:21873635
MGI:1926002|MGI:4868209 (MGI:3708435|PMID:17145758), (MGI:5620532|PMID:25568321), (MGI:6112811|PMID:29287114)
RGD PMID:11514575 PMID:12163485 PMID:17145758 PMID:25568321 PMID:29287114 More... MGI:3708435 MGI:5620532 MGI:6112811, RGD:13792537 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO
IBA
(MGI:5620532|PMID:25568321)
PMID:21873635
RGD PMID:25568321 PMID:21873635 MGI:5620532, RGD:13792537 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Slc35b2 solute carrier family 35 member B2 involved_in ISO (PMID:35325049) RGD PMID:35325049 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO
GO_REF:0000041
(MGI:5544658|PMID:24161523)
UniProt
RGD
PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat1 beta-1,3-glucuronyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:26,167,174...26,250,153
Ensembl chr 9:26,167,174...26,250,153
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:25893793)
PMID:21873635
(PMID:21763480)
RGD PMID:21763480 PMID:25893793 PMID:21873635 RGD:13792537 NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:11788602)
MGI:1927166 (MGI:4941099|PMID:21138417)
RGD PMID:11788602 PMID:21138417 MGI:4941099 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Cytl1 cytokine like 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886
JBrowse link
G Eml3 EMAP like 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,826,354...205,837,790
Ensembl chr 1:205,817,378...205,837,807
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
ISS
IBA
(PMID:24425863)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:24425863 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:17189265)
GO_REF:0000024
RGD
UniProt
PMID:17189265 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISO
ISS
IBA
(PMID:17189265), (PMID:26027496)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:17189265 PMID:26027496 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO (PMID:12163485) RGD PMID:12163485 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
dermatan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 acts_upstream_of_or_within ISO (PMID:11470797) RGD PMID:11470797 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548
JBrowse link
G Dse dermatan sulfate epimerase involved_in ISO (PMID:16505484) RGD PMID:16505484 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
dermatan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
ISO (PMID:25893793)
(PMID:21763480)
RGD PMID:21763480 PMID:25893793 NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
ISO (PMID:25893793)
(PMID:21763480)
RGD PMID:21763480 PMID:25893793 NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
JBrowse link
G Ext1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10639137), (PMID:9620772)
(MGI:3687782|PMID:10639137), (MGI:7276136|PMID:30377379)
(MGI:4431165|PMID:20080592)
RGD PMID:9620772 PMID:10639137 PMID:20080592 PMID:30377379 MGI:3687782 MGI:4431165 MGI:7276136 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17761672)
MGI:894663 (MGI:3687782|PMID:10639137)
MGI:3608690 (MGI:3608483|PMID:16236767)
RGD PMID:10639137 PMID:16236767 PMID:17761672 MGI:3608483 MGI:3687782 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 involved_in ISO (PMID:11390981) RGD PMID:11390981 NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:11390981), (PMID:28132690), (PMID:28148688), (PMID:35676258)
(MGI:3844390|PMID:19336225)
RGD PMID:11390981 PMID:19336225 PMID:28132690 PMID:28148688 PMID:35676258 MGI:3844390 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898
JBrowse link
G Glce glucuronic acid epimerase involved_in ISO
IBA
(PMID:20118238), (PMID:30872481)
(MGI:2135754|PMID:11279150), (MGI:7276136|PMID:30377379)
PMID:21873635
RGD PMID:11279150 PMID:20118238 PMID:30377379 PMID:30872481 PMID:21873635 MGI:2135754 MGI:7276136, RGD:13792537 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in ISO MGI:4439258 (MGI:4438521|PMID:19889634), (MGI:7276136|PMID:30377379) RGD PMID:19889634 PMID:30377379 MGI:4438521 MGI:7276136 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 involved_in ISO
IEA
(MGI:1098372|PMID:9346953), (MGI:7276136|PMID:30377379), (MGI:7278686|PMID:24247246)
GO_REF:0000107
RGD
Ensembl
PMID:9346953 PMID:24247246 PMID:30377379 GO_REF:0000107 MGI:1098372 MGI:7276136 MGI:7278686 NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 involved_in ISO MGI:5566804 (MGI:7276134|PMID:26731579) RGD PMID:26731579 MGI:7276134 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399
JBrowse link
G Hs3st3a1 heparan sulfate-glucosamine 3-sulfotransferase 3A1 involved_in ISO MGI:5312610 (MGI:6871814|PMID:34653670) RGD PMID:34653670 MGI:6871814 NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676
JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 involved_in ISO (MGI:1860201|PMID:10520990) RGD PMID:10520990 MGI:1860201 NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970
JBrowse link
G Hs3st4 heparan sulfate-glucosamine 3-sulfotransferase 4 involved_in ISO (MGI:7276136|PMID:30377379) RGD PMID:30377379 MGI:7276136 NCBI chr 1:178,539,078...178,944,850
Ensembl chr 1:178,539,093...178,944,107
JBrowse link
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 involved_in ISO (MGI:3579706|PMID:15303968) RGD PMID:15303968 MGI:3579706 NCBI chr10:13,781,999...13,788,133
Ensembl chr10:13,781,993...13,788,133
JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within
involved_in
ISO MGI:3715259 (MGI:3715036|PMID:17405882)
(MGI:2664002|PMID:12611590), (MGI:7276126|PMID:15226404), (MGI:7276136|PMID:30377379)
RGD PMID:12611590 PMID:15226404 PMID:17405882 PMID:30377379 MGI:2664002 MGI:3715036 MGI:7276126 MGI:7276136 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 involved_in ISO (MGI:2664002|PMID:12611590), (MGI:7276126|PMID:15226404), (MGI:7276136|PMID:30377379) RGD PMID:12611590 PMID:15226404 PMID:30377379 MGI:2664002 MGI:7276126 MGI:7276136 NCBI chr  X:130,966,547...131,261,629
Ensembl chr  X:130,968,385...131,261,492
JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 involved_in ISO (MGI:2664002|PMID:12611590), (MGI:7276126|PMID:15226404) RGD PMID:12611590 PMID:15226404 MGI:2664002 MGI:7276126 NCBI chr15:96,281,502...97,000,804
Ensembl chr15:96,281,646...97,000,462
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:15102889 RGD:1580511 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IMP
ISO
PMID:9915799
MGI:3589211|MGI:3589383 (MGI:3805404|PMID:18385133), (MGI:3806218|PMID:18487608), (MGI:6852186|PMID:23846497), (MGI:7276136|PMID:30377379)
RGD PMID:18385133 PMID:18487608 PMID:23846497 PMID:30377379 PMID:9915799 MGI:3805404 MGI:3806218 MGI:6852186 MGI:7276136, RGD:12907548 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within
involved_in
ISO MGI:1913285 (MGI:1343737|PMID:10466727)
(MGI:3806218|PMID:18487608), (MGI:5810238|PMID:27387504), (MGI:65699|PMID:8294485), (MGI:7276136|PMID:30377379)
RGD PMID:8294485 PMID:10466727 PMID:18487608 PMID:27387504 PMID:30377379 MGI:1343737 MGI:3806218 MGI:5810238 MGI:65699 MGI:7276136 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in ISO (PMID:9915799)
MGI:3806156 (MGI:3805404|PMID:18385133)
RGD PMID:9915799 PMID:18385133 MGI:3805404 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Slc35d2 solute carrier family 35 member D2 acts_upstream_of_positive_effect ISO (PMID:15082721) RGD PMID:15082721 NCBI chr17:987,899...1,019,747
Ensembl chr17:988,157...1,019,743
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:1857642 (MGI:5498591|PMID:23760952) RGD PMID:23760952 MGI:5498591 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:17189265)
UniProt
RGD
PMID:17189265 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000041
(PMID:17189265), (PMID:26027496)
PMID:21873635
UniProt
RGD
PMID:17189265 PMID:26027496 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
heparan sulfate proteoglycan biosynthetic process, enzymatic modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 involved_in ISO (PMID:12138164) RGD PMID:12138164 NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653
JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1353793|PMID:10644753)
PMID:21873635
RGD PMID:10644753 PMID:21873635 MGI:1353793, RGD:13792537 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1353793|PMID:10644753)
PMID:21873635
RGD PMID:10644753 PMID:21873635 MGI:1353793, RGD:13792537 NCBI chr  X:130,966,547...131,261,629
Ensembl chr  X:130,968,385...131,261,492
JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 acts_upstream_of_or_within ISO (MGI:1353793|PMID:10644753) RGD PMID:10644753 MGI:1353793 NCBI chr15:96,281,502...97,000,804
Ensembl chr15:96,281,646...97,000,462
JBrowse link
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 involved_in ISO (PMID:17761672), (PMID:36593275) RGD PMID:17761672 PMID:36593275 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 involved_in ISO (PMID:17761672), (PMID:36593275) RGD PMID:17761672 PMID:36593275 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1934916 (MGI:2150438|PMID:11457822)
RGD PMID:11457822 PMID:21873635 MGI:2150438, RGD:13792537 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IDA
IBA
ISO
PMID:1379236
PMID:21873635
(MGI:6870964|PMID:10758005)
PMID:8483907
RGD PMID:10758005 PMID:1379236 PMID:21873635 PMID:8483907 MGI:6870964, RGD:68801, RGD:13792537, RGD:151356652 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in ISO
IBA
(MGI:6870964|PMID:10758005)
PMID:21873635
RGD PMID:10758005 PMID:21873635 MGI:6870964, RGD:13792537 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in ISO
IBA
(PMID:9915799)
PMID:21873635
RGD PMID:9915799 PMID:21873635 RGD:13792537 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:213,787,010...214,119,514
Ensembl chr 2:213,787,006...214,115,373
JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
positive regulation of heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS
(PMID:15853773)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15853773 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24425863)
UniProt
RGD
PMID:24425863 GO_REF:0000024 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:15853773) RGD PMID:15853773 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
positive regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,072,908...6,075,161
Ensembl chr16:6,072,833...6,075,161
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
regulation of heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:28404855) RGD PMID:28404855 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      primary metabolic process 9986
        protein metabolic process 4578
          glycoprotein metabolic process 378
            proteoglycan metabolic process 91
              proteoglycan biosynthetic process 66
                chondroitin sulfate proteoglycan biosynthetic process + 26
                dermatan sulfate proteoglycan biosynthetic process + 5
                heparan sulfate proteoglycan biosynthetic process + 31
                negative regulation of proteoglycan biosynthetic process 1
                positive regulation of proteoglycan biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      organic substance metabolic process 10895
        organonitrogen compound metabolic process 5645
          protein metabolic process 4578
            glycoprotein metabolic process 378
              proteoglycan metabolic process 91
                proteoglycan biosynthetic process 66
                  chondroitin sulfate proteoglycan biosynthetic process + 26
                  dermatan sulfate proteoglycan biosynthetic process + 5
                  heparan sulfate proteoglycan biosynthetic process + 31
                  negative regulation of proteoglycan biosynthetic process 1
                  positive regulation of proteoglycan biosynthetic process + 5
paths to the root