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ONTOLOGY REPORT - ANNOTATIONS

Term:chondroitin sulfate biosynthetic process
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Accession:GO:0030206 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
Synonyms:exact_synonym: chondroitin sulfate anabolism;   chondroitin sulfate biosynthesis;   chondroitin sulfate formation;   chondroitin sulfate synthesis;   chondroitin sulphate biosynthesis;   chondroitin sulphate biosynthetic process


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chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07047835.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 5:48,925,362...48,927,475 JBrowse link
G B4galnt3 beta-1,4-N-acetyl-galactosaminyl transferase 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 4:153,410,907...153,509,019
Ensembl chr 4:153,409,004...153,509,321 		JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294 		JBrowse link
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1926173|MGI:2681120 (MGI:5462286|PMID:22952769), (MGI:7266375|PMID:17253960)
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
(PMID:12761225)		 RGD PMID:12761225 PMID:17253960 PMID:22952769 PMID:22952873 PMID:21873635 MGI:5462280 MGI:5462286 MGI:7266375, RGD:13792537 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878 		JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 ISO (PMID:11056388)
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)		 RGD PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057 		JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,712...122,837,935
Ensembl chr 4:122,824,022...122,838,019 		JBrowse link
G Chst3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO
ISS		 GO_REF:0000107
PMID:21873635
(MGI:1206144|PMID:9597547)
GO_REF:0000024
(PMID:15215498), (PMID:9883891)
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)		 Ensembl
RGD
UniProt		 PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:16495484 More... GO_REF:0000024 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:1600854, RGD:13792537 NCBI chr20:28,114,387...28,152,046
Ensembl chr20:28,114,404...28,121,807 		JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in IBA
ISO		 PMID:21873635
(PMID:10781596)		 RGD PMID:10781596 PMID:21873635 RGD:13792537 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:106576 (MGI:5462286|PMID:22952769)
PMID:21873635
(PMID:11514575)		 RGD PMID:11514575 PMID:22952769 PMID:21873635 MGI:5462286, RGD:13792537 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601 		JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in ISO
IBA		 MGI:106576 (MGI:7266375|PMID:17253960)
PMID:21873635		 RGD PMID:17253960 PMID:21873635 MGI:7266375, RGD:13792537 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA		 (PMID:11514575), (PMID:12163485)
PMID:21873635
MGI:1926002|MGI:4868209 (MGI:3708435|PMID:17145758), (MGI:5620532|PMID:25568321), (MGI:6112811|PMID:29287114)		 RGD PMID:11514575 PMID:12163485 PMID:17145758 PMID:25568321 PMID:29287114 More... MGI:3708435 MGI:5620532 MGI:6112811, RGD:13792537 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO
IBA		 (MGI:5620532|PMID:25568321)
PMID:21873635		 RGD PMID:25568321 PMID:21873635 MGI:5620532, RGD:13792537 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839 		JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:5544658|PMID:24161523)		 UniProt
RGD		 PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    cellular process 17330
      cellular metabolic process 7444
        cellular biosynthetic process 2909
          sulfur compound biosynthetic process 129
            chondroitin sulfate biosynthetic process 18
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      organic substance metabolic process 11557
        carbohydrate derivative metabolic process 1032
          glycoprotein metabolic process 394
            proteoglycan metabolic process 97
              chondroitin sulfate proteoglycan metabolic process 41
                chondroitin sulfate metabolic process 34
                  chondroitin sulfate biosynthetic process 18
paths to the root