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ONTOLOGY REPORT - ANNOTATIONS

Term:proteoglycan metabolic process
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Accession:GO:0006029 term browser browse the term
Definition:The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
Synonyms:exact_synonym: proteoglycan metabolism
 narrow_synonym: proteoglycan sulfate transfer

show annotations for term's descendants           Sort by:
 
proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt7 beta-1,4-galactosyltransferase 7 involved_in ISO
ISS		 (PMID:16583246)
GO_REF:0000024		 RGD
UniProt		 PMID:16583246 GO_REF:0000024 NCBI chr17:9,549,605...9,558,672
Ensembl chr17:9,550,028...9,558,634 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:96533 (MGI:4999722|PMID:16935278)		 Ensembl
RGD		 PMID:16935278 GO_REF:0000107 MGI:4999722 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain acts_upstream_of_or_within ISO MGI:1856399 (MGI:2664273|PMID:3070812) RGD PMID:3070812 MGI:2664273 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1857275 (MGI:2664273|PMID:3070812), (MGI:55057|PMID:7276808)		 Ensembl
RGD		 PMID:3070812 PMID:7276808 GO_REF:0000107 MGI:2664273 MGI:55057 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:88177 (MGI:4999722|PMID:16935278) RGD PMID:16935278 MGI:4999722 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:17140817 RGD:2324893 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032202.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr18:54,206,651...54,207,523 JBrowse link
G Chpf chondroitin polymerizing factor acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:12761225)
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
PMID:21873635		 RGD PMID:12761225 PMID:22952769 PMID:22952873, PMID:21873635, PMID:21873635 MGI:5462280 MGI:5462286, RGD:13792537, RGD:13792537 NCBI chr 9:82,669,199...82,673,898
Ensembl chr 9:82,669,204...82,673,898 		JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:7,108,461...7,113,940
Ensembl chr 4:7,108,462...7,113,919 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within
involved_in		 ISO (PMID:11056388)
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)		 RGD PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:16,199,975...16,218,404
Ensembl chr12:16,200,019...16,201,632 		JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,223,846...122,244,848
Ensembl chr 4:122,224,535...122,237,754 		JBrowse link
G Chst3 carbohydrate sulfotransferase 3 acts_upstream_of_or_within
involved_in		 IEA
ISO
IBA		 GO_REF:0000107
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)
(PMID:9883891)
PMID:21873635		 Ensembl
RGD		 PMID:9597547 PMID:9883891 PMID:11696535, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:13792537, RGD:13792537 NCBI chr20:29,731,828...29,768,656
Ensembl chr20:29,731,816...29,738,506 		JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in ISO
IBA		 (PMID:10781596)
PMID:21873635		 RGD PMID:10781596, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr  X:2,623,018...2,657,155
Ensembl chr  X:2,623,024...2,657,155 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11514575)
MGI:106576 (MGI:5462286|PMID:22952769)
PMID:21873635		 RGD PMID:11514575 PMID:22952769, PMID:21873635, PMID:21873635 MGI:5462286, RGD:13792537, RGD:13792537 NCBI chr 1:127,010,587...127,071,570
Ensembl chr 1:127,010,588...127,071,570 		JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:54,243,626...54,497,475
Ensembl chr18:54,243,949...54,496,585 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA		 (PMID:11514575), (PMID:12163485)
PMID:21873635		 RGD PMID:11514575 PMID:12163485, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044 		JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:122,700,396...122,746,815
Ensembl chr 5:122,699,587...122,746,839 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:2675908|PMID:14505572)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO		 GO_REF:0000041
(MGI:5544658|PMID:24161523)		 UniProt
RGD		 PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485 		JBrowse link
chondroitin sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (MGI:5490850|PMID:23086929) RGD PMID:23086929 MGI:5490850 NCBI chr 4:52,147,641...52,166,276
Ensembl chr 4:52,147,641...52,167,122 		JBrowse link
chondroitin sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990|MGI:3810994 (MGI:3799383|PMID:18539921), (MGI:3809386|PMID:18695242) RGD PMID:18539921 PMID:18695242 MGI:3799383 MGI:3809386 NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013
Ensembl chr 5:90,188,043...90,218,013 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within ISO MGI:4868209|MGI:4947395 (MGI:4849906|PMID:20812917), (MGI:4946456|PMID:21148564) RGD PMID:20812917 PMID:21148564 MGI:4849906 MGI:4946456 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798 		JBrowse link
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586 		JBrowse link
G Dsel dermatan sulfate epimerase-like acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5583872 (MGI:5583874|PMID:22496542)
PMID:21873635		 RGD PMID:22496542, PMID:21873635, PMID:21873635 MGI:5583874, RGD:13792537, RGD:13792537 NCBI chr13:1,942,384...1,948,563
Ensembl chr13:1,942,499...1,946,508 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:6478099|PMID:32201365) RGD PMID:32201365 MGI:6478099 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068 		JBrowse link
chondroitin sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat1 beta-1,3-glucuronyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:27,777,024...27,804,368
Ensembl chr 8:27,777,179...27,804,515 		JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:29,984,077...30,068,649
Ensembl chr 9:29,984,077...30,068,649 		JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in ISO
IBA		 (PMID:21763480), (PMID:25893793)
PMID:21873635		 RGD PMID:21763480 PMID:25893793, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:11788602)
MGI:1927166 (MGI:4941099|PMID:21138417)		 RGD PMID:11788602 PMID:21138417 MGI:4941099 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044 		JBrowse link
G Cytl1 cytokine like 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr14:77,805,137...77,810,147
Ensembl chr14:77,805,130...77,810,147 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
ISS
IBA		 (PMID:24425863)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:24425863, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 8:104,724,728...104,790,639
Ensembl chr 8:104,724,743...104,790,639 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:17189265)
PMID:21873635		 UniProt
Ensembl
RGD		 PMID:17189265, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA
IBA
ISS
ISO		 GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:17189265), (PMID:26027496)		 Ensembl
UniProt
RGD		 PMID:17189265 PMID:26027496, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485 		JBrowse link
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO (PMID:12163485) RGD PMID:12163485 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798 		JBrowse link
dermatan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:16,199,975...16,218,404
Ensembl chr12:16,200,019...16,201,632 		JBrowse link
G Chst14 carbohydrate sulfotransferase 14 involved_in ISO (PMID:11470797) RGD PMID:11470797 NCBI chr 3:110,734,105...110,736,162
Ensembl chr 3:110,734,105...110,736,162 		JBrowse link
G Dse dermatan sulfate epimerase involved_in ISO (PMID:16505484) RGD PMID:16505484 NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586 		JBrowse link
dermatan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within
involved_in		 ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987)		 RGD PMID:19751987 PMID:19834056 PMID:24036510 MGI:4397742 MGI:4414887 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762 		JBrowse link
dermatan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586 		JBrowse link
G Dsel dermatan sulfate epimerase-like acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5583872 (MGI:5583874|PMID:22496542)
PMID:21873635		 RGD PMID:22496542, PMID:21873635, PMID:21873635 MGI:5583874, RGD:13792537, RGD:13792537 NCBI chr13:1,942,384...1,948,563
Ensembl chr13:1,942,499...1,946,508 		JBrowse link
dermatan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in ISO (PMID:21763480), (PMID:25893793) RGD PMID:21763480 PMID:25893793 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044 		JBrowse link
dermatan sulfate proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst14 carbohydrate sulfotransferase 14 involved_in ISO
IBA		 (PMID:11470797)
PMID:21873635		 RGD PMID:11470797, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:110,734,105...110,736,162
Ensembl chr 3:110,734,105...110,736,162 		JBrowse link
heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in ISO (PMID:21763480), (PMID:25893793) RGD PMID:21763480 PMID:25893793 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:10639137), (PMID:9620772)
(MGI:4431165|PMID:20080592)
(MGI:3687782|PMID:10639137)
(MGI:3687782|PMID:10639137), (MGI:4431165|PMID:20080592)		 RGD PMID:9620772 PMID:10639137 PMID:20080592 MGI:3687782 MGI:4431165 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:17761672)
MGI:3608690 (MGI:3608483|PMID:16236767)		 RGD PMID:16236767 PMID:17761672 MGI:3608483 NCBI chr 3:82,602,784...82,734,557
Ensembl chr 3:82,602,785...82,734,533 		JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:28132690), (PMID:28148688) RGD PMID:28132690 PMID:28148688 NCBI chr15:48,420,419...48,465,171
Ensembl chr15:48,422,492...48,445,592 		JBrowse link
G Glce glucuronic acid epimerase involved_in ISO
IBA		 (PMID:20118238), (PMID:30872481)
(MGI:2135754|PMID:11279150)
PMID:21873635		 RGD PMID:11279150 PMID:20118238 PMID:30872481, PMID:21873635, PMID:21873635 MGI:2135754, RGD:13792537, RGD:13792537 NCBI chr 8:67,006,588...67,073,723
Ensembl chr 8:67,006,592...67,040,005 		JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:3715259 (MGI:3715036|PMID:17405882) RGD PMID:17405882 MGI:3715036 NCBI chr 9:42,620,006...42,659,184
Ensembl chr 9:42,620,006...42,659,184 		JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:15102889 RGD:1580511 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IMP PMID:9915799 UniProt PMID:9915799, PMID:9915799 RGD:12907548, RGD:12907548 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885 		JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within ISO MGI:1913285 (MGI:1343737|PMID:10466727) RGD PMID:10466727 MGI:1343737 NCBI chr15:3,995,797...4,006,491
Ensembl chr15:3,996,048...4,006,491 		JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in ISO (PMID:9915799) RGD PMID:9915799 NCBI chr 2:227,736,491...227,903,657
Ensembl chr 2:227,738,650...227,890,077 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:2675908|PMID:14505572)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:1857642 (MGI:5498591|PMID:23760952) RGD PMID:23760952 MGI:5498591 NCBI chr13:90,379,203...90,405,627
Ensembl chr13:90,380,632...90,405,591 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
IBA
ISS
ISO		 GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:17189265)		 UniProt
RGD		 PMID:17189265, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537, RGD:13792537 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632 		JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA
ISO
IBA
ISS		 GO_REF:0000041
(PMID:17189265), (PMID:26027496)
PMID:21873635
GO_REF:0000024		 UniProt
RGD		 PMID:17189265 PMID:26027496, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537, RGD:13792537 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485 		JBrowse link
heparan sulfate proteoglycan biosynthetic process, enzymatic modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517 		JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 involved_in ISO (PMID:12138164) RGD PMID:12138164 NCBI chr20:40,236,437...40,545,502
Ensembl chr20:40,236,437...40,545,494 		JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1353793|PMID:10644753)
PMID:21873635		 RGD PMID:10644753, PMID:21873635, PMID:21873635 MGI:1353793, RGD:13792537, RGD:13792537 NCBI chr 9:42,620,006...42,659,184
Ensembl chr 9:42,620,006...42,659,184 		JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 acts_upstream_of_or_within
involved_in		 IBA
ISO		 PMID:21873635
(MGI:1353793|PMID:10644753)		 RGD PMID:10644753, PMID:21873635, PMID:21873635 MGI:1353793, RGD:13792537, RGD:13792537 NCBI chr  X:138,675,326...138,972,774
Ensembl chr  X:138,677,580...138,972,684 		JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 acts_upstream_of_or_within ISO (MGI:1353793|PMID:10644753) RGD PMID:10644753 MGI:1353793 NCBI chr15:104,448,479...105,254,540
Ensembl chr15:104,448,600...105,254,214 		JBrowse link
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 involved_in ISO (PMID:17761672) RGD PMID:17761672 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 involved_in ISO (PMID:17761672) RGD PMID:17761672 NCBI chr 3:82,602,784...82,734,557
Ensembl chr 3:82,602,785...82,734,533 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1934916 (MGI:2150438|PMID:11457822)
PMID:21873635		 RGD PMID:11457822, PMID:21873635, PMID:21873635 MGI:2150438, RGD:13792537, RGD:13792537 NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885 		JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr15:3,995,797...4,006,491
Ensembl chr15:3,996,048...4,006,491 		JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in ISO
IBA		 (PMID:9915799)
PMID:21873635		 RGD PMID:9915799, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:227,736,491...227,903,657
Ensembl chr 2:227,738,650...227,890,077 		JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:229,170,781...229,496,732
Ensembl chr 2:229,196,616...229,496,516 		JBrowse link
G NEWGENE_1304700 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr15:3,750,058...3,760,616
Ensembl chr15:3,754,262...3,760,663 		JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07030903.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr10:108,469,856...108,473,377 JBrowse link
G Gpc1 glypican 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12732622)		 Ensembl
UniProt
RGD		 PMID:12732622 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818 		JBrowse link
G Hpse heparanase involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12213822)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12213822 GO_REF:0000024 GO_REF:0000107 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224 		JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO (PMID:15146460) RGD PMID:15146460 NCBI chr10:108,469,312...108,479,094 JBrowse link
heparan sulfate proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sulf1 sulfatase 1 involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(MGI:5306289|PMID:18687675)
PMID:21873635
GO_REF:0000104
(PMID:18687675), (PMID:19666466), (PMID:19822709)		 UniProt
RGD		 PMID:18687675 PMID:19666466 PMID:19822709, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000104 MGI:5306289, RGD:13792537, RGD:13792537 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329 		JBrowse link
G Sulf2 sulfatase 2 involved_in ISO
IBA		 (PMID:18687675)
(MGI:5306289|PMID:18687675)
PMID:21873635		 RGD PMID:18687675, PMID:21873635, PMID:21873635 MGI:5306289, RGD:13792537, RGD:13792537 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831 		JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804 		JBrowse link
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07060833.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 4:96,562,725...96,564,611 JBrowse link
G Bgn biglycan acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204 		JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323 		JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3807344|PMID:18757743)		 Ensembl
RGD		 PMID:18757743 GO_REF:0000107 MGI:3807344 NCBI chr 2:56,503,002...56,681,334
Ensembl chr 2:56,502,807...56,679,955 		JBrowse link
G Mamdc2 MAM domain containing 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 1:241,071,110...241,223,798
Ensembl chr 1:241,072,072...241,155,537 		JBrowse link
G Ndnf neuron-derived neurotrophic factor acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 4:96,528,830...96,565,780 JBrowse link
G Prss34 protease, serine, 34 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:14,656,812...14,658,569
Ensembl chr10:14,656,812...14,658,569 		JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr20:29,654,926...29,679,927
Ensembl chr20:29,655,226...29,677,926 		JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr16:28,372,067...28,716,762
Ensembl chr16:28,372,411...28,716,885 		JBrowse link
positive regulation of heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
ISS		 (PMID:15853773)
GO_REF:0000024		 RGD
UniProt		 PMID:15853773 GO_REF:0000024 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
ISS		 (PMID:24425863)
GO_REF:0000024		 RGD
UniProt		 PMID:24425863 GO_REF:0000024 NCBI chr 8:104,724,728...104,790,639
Ensembl chr 8:104,724,743...104,790,639 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:15853773) RGD PMID:15853773 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514 		JBrowse link
positive regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,962,737...6,964,987
Ensembl chr16:6,962,722...6,964,989 		JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804 		JBrowse link
proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:1856465 (MGI:2664273|PMID:3070812)		 Ensembl
RGD		 PMID:3070812 GO_REF:0000107 MGI:2664273 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441 		JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 involved_in ISO
IEA		 (PMID:29443383)
GO_REF:0000107		 RGD
Ensembl		 PMID:29443383 GO_REF:0000107 NCBI chr 5:173,423,475...173,425,611
Ensembl chr 5:173,423,475...173,425,611 		JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:9,549,605...9,558,672
Ensembl chr17:9,550,028...9,558,634 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G Cant1 calcium activated nucleotidase 1 involved_in ISO
ISS
IBA		 (PMID:22539336)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:22539336, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr10:107,432,500...107,445,634
Ensembl chr10:107,432,506...107,445,522 		JBrowse link
G Chst10 carbohydrate sulfotransferase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 9:45,528,928...45,559,365
Ensembl chr 9:45,528,928...45,559,140 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716 		JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:16,199,975...16,218,404
Ensembl chr12:16,200,019...16,201,632 		JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:122,223,846...122,244,848
Ensembl chr 4:122,224,535...122,237,754 		JBrowse link
G Chst8 carbohydrate sulfotransferase 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:10988300)
(MGI:1928003|PMID:10988300)
PMID:21873635		 RGD PMID:10988300, PMID:21873635, PMID:21873635 MGI:1928003, RGD:13792537, RGD:13792537 NCBI chr 1:90,542,095...90,685,257
Ensembl chr 1:90,542,096...90,685,257 		JBrowse link
G Chst9 carbohydrate sulfotransferase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr18:6,833,408...7,115,815
Ensembl chr18:6,834,365...7,081,356 		JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:4946896|PMID:21185280) RGD PMID:21185280 MGI:4946896 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068 		JBrowse link
G Fam20b FAM20B, glycosaminoglycan xylosylkinase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr13:74,280,173...74,333,463
Ensembl chr13:74,280,173...74,331,214 		JBrowse link
G Foxl1 forkhead box L1 acts_upstream_of_or_within ISO MGI:2178230 (MGI:2153304|PMID:11555641) RGD PMID:11555641 MGI:2153304 NCBI chr19:53,054,887...53,058,624
Ensembl chr19:53,055,745...53,056,770 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:12746903), (PMID:9564845)
GO_REF:0000107		 RGD
Ensembl		 PMID:9564845 PMID:12746903 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IMP
ISS
ISO		 GO_REF:0000024
(PMID:11087729)		 UniProt
RGD		 PMID:11087729, PMID:19001053 GO_REF:0000024, RGD:2313142 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632 		JBrowse link
G Xylt2 xylosyltransferase 2 acts_upstream_of_or_within ISO MGI:3714171 (MGI:3713963|PMID:17517600) RGD PMID:17517600 MGI:3713963 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485 		JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      cellular metabolic process 11078
        cellular macromolecule metabolic process 8496
          glycoprotein metabolic process 364
            proteoglycan metabolic process 79
              cell wall proteoglycan metabolic process + 0
              chondroitin sulfate proteoglycan metabolic process + 36
              dermatan sulfate proteoglycan metabolic process + 7
              heparan sulfate proteoglycan metabolic process + 29
              proteoglycan biosynthetic process + 54
              proteoglycan catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 20082
    metabolic process 12142
      organic substance metabolic process 11647
        macromolecule metabolic process 10055
          protein metabolic process 6081
            glycoprotein metabolic process 364
              proteoglycan metabolic process 79
                cell wall proteoglycan metabolic process + 0
                chondroitin sulfate proteoglycan metabolic process + 36
                dermatan sulfate proteoglycan metabolic process + 7
                heparan sulfate proteoglycan metabolic process + 29
                proteoglycan biosynthetic process + 54
                proteoglycan catabolic process + 5
paths to the root