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ONTOLOGY REPORT - ANNOTATIONS


Term:proteoglycan metabolic process
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Accession:GO:0006029 term browser browse the term
Definition:The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
Synonyms:exact_synonym: proteoglycan metabolism
 narrow_synonym: proteoglycan sulfate transfer



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proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO MGI:1347346 (MGI:6193362|PMID:29618652) RGD PMID:29618652 MGI:6193362 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 involved_in ISO MGI:2146046 (MGI:6193362|PMID:29618652) RGD PMID:29618652 MGI:6193362 NCBI chr 8:90,704,727...90,744,331
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:16583246)
UniProt
RGD
PMID:16583246 GO_REF:0000024 NCBI chr17:9,018,514...9,027,591
Ensembl chr17:9,018,935...9,027,573
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:96533 (MGI:4999722|PMID:16935278)
Ensembl
RGD
PMID:16935278 GO_REF:0000107 MGI:4999722 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Col11a1 collagen type XI alpha 1 chain acts_upstream_of_or_within ISO MGI:1856399 (MGI:2664273|PMID:3070812) RGD PMID:3070812 MGI:2664273 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857275 (MGI:2664273|PMID:3070812), (MGI:55057|PMID:7276808)
Ensembl
RGD
PMID:3070812 PMID:7276808 GO_REF:0000107 MGI:2664273 MGI:55057 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:88177 (MGI:4999722|PMID:16935278) RGD PMID:16935278 MGI:4999722 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:17140817 RGD:2324893 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032202.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
(PMID:12761225)
RGD PMID:12761225 PMID:22952769 PMID:22952873 PMID:21873635 MGI:5462280 MGI:5462286, RGD:13792537 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
ISO (PMID:11056388)
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)
RGD PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,824,712...122,837,935
Ensembl chr 4:122,824,022...122,838,019
JBrowse link
G Chst3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:15215498), (PMID:9883891)
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9597547 PMID:9883891 PMID:11696535 PMID:15215498 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:13792537 NCBI chr20:28,114,387...28,152,046
Ensembl chr20:28,114,404...28,121,807
JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in IBA
ISO
PMID:21873635
(PMID:10781596)
RGD PMID:10781596 PMID:21873635 RGD:13792537 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:11514575)
MGI:106576 (MGI:5462286|PMID:22952769)
RGD PMID:11514575 PMID:22952769 PMID:21873635 MGI:5462286, RGD:13792537 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:52,644,356...52,901,257
Ensembl chr18:52,644,461...52,898,098
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA
(PMID:11514575), (PMID:12163485)
PMID:21873635
RGD PMID:11514575 PMID:12163485 PMID:21873635 RGD:13792537 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO
GO_REF:0000041
(MGI:5544658|PMID:24161523)
UniProt
RGD
PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (MGI:5490850|PMID:23086929) RGD PMID:23086929 MGI:5490850 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
chondroitin sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990|MGI:3810994 (MGI:3799383|PMID:18539921), (MGI:3809386|PMID:18695242) RGD PMID:18539921 PMID:18695242 MGI:3799383 MGI:3809386 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within ISO MGI:4868209|MGI:4947395 (MGI:4849906|PMID:20812917), (MGI:4946456|PMID:21148564) RGD PMID:20812917 PMID:21148564 MGI:4849906 MGI:4946456 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5583872 (MGI:5583874|PMID:22496542)
RGD PMID:22496542 PMID:21873635 MGI:5583874, RGD:13792537 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:6478099|PMID:32201365) RGD PMID:32201365 MGI:6478099 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
chondroitin sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat1 beta-1,3-glucuronyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:26,167,174...26,250,153
Ensembl chr 9:26,167,174...26,250,153
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:21763480)
(PMID:25893793)
RGD PMID:21763480 PMID:25893793 PMID:21873635 RGD:13792537 NCBI chr 1:205,817,374...205,823,928 JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:11788602)
MGI:1927166 (MGI:4941099|PMID:21138417)
RGD PMID:11788602 PMID:21138417 MGI:4941099 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Cytl1 cytokine like 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
ISS
IBA
(PMID:24425863)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:24425863 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:17189265)
UniProt
RGD
PMID:17189265 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISO
IBA
ISS
(PMID:17189265), (PMID:26027496)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:17189265 PMID:26027496 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO (PMID:12163485) RGD PMID:12163485 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
dermatan sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 acts_upstream_of_or_within ISO (PMID:11470797) RGD PMID:11470797 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548
JBrowse link
G Dse dermatan sulfate epimerase involved_in ISO (PMID:16505484) RGD PMID:16505484 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
dermatan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase involved_in
acts_upstream_of_or_within
ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987)
RGD PMID:19751987 PMID:19834056 PMID:24036510 MGI:4397742 MGI:4414887 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
dermatan sulfate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dse dermatan sulfate epimerase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dsel dermatan sulfate epimerase-like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5583872 (MGI:5583874|PMID:22496542)
RGD PMID:22496542 PMID:21873635 MGI:5583874, RGD:13792537 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
JBrowse link
dermatan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
ISO (PMID:25893793)
(PMID:21763480)
RGD PMID:21763480 PMID:25893793 NCBI chr 1:205,817,374...205,823,928 JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
dermatan sulfate proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst14 carbohydrate sulfotransferase 14 involved_in IBA
ISO
PMID:21873635
(PMID:11470797)
RGD PMID:11470797 PMID:21873635 RGD:13792537 NCBI chr 3:105,916,481...105,918,538
Ensembl chr 3:105,916,466...105,918,548
JBrowse link
heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in
acts_upstream_of_or_within
ISO (PMID:25893793)
(PMID:21763480)
RGD PMID:21763480 PMID:25893793 NCBI chr 1:205,817,374...205,823,928 JBrowse link
G Ext1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10639137), (PMID:9620772)
(MGI:4431165|PMID:20080592)
(MGI:3687782|PMID:10639137)
RGD PMID:9620772 PMID:10639137 PMID:20080592 MGI:3687782 MGI:4431165 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:17761672)
MGI:3608690 (MGI:3608483|PMID:16236767)
RGD PMID:16236767 PMID:17761672 MGI:3608483 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 involved_in ISO (PMID:28132690), (PMID:28148688) RGD PMID:28132690 PMID:28148688 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898
JBrowse link
G Glce glucuronic acid epimerase involved_in ISO
IBA
(PMID:20118238), (PMID:30872481)
(MGI:2135754|PMID:11279150)
PMID:21873635
RGD PMID:11279150 PMID:20118238 PMID:30872481 PMID:21873635 MGI:2135754, RGD:13792537 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:3715259 (MGI:3715036|PMID:17405882) RGD PMID:17405882 MGI:3715036 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:15102889 RGD:1580511 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IMP PMID:9915799 UniProt PMID:9915799 RGD:12907548 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within ISO MGI:1913285 (MGI:1343737|PMID:10466727) RGD PMID:10466727 MGI:1343737 NCBI chr15:3,563,358...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in ISO (PMID:9915799) RGD PMID:9915799 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:1857642 (MGI:5498591|PMID:23760952) RGD PMID:23760952 MGI:5498591 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:17189265)
UniProt
RGD
PMID:17189265 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000041
(PMID:17189265), (PMID:26027496)
PMID:21873635
UniProt
RGD
PMID:17189265 PMID:26027496 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
heparan sulfate proteoglycan biosynthetic process, enzymatic modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Hs3st5 heparan sulfate-glucosamine 3-sulfotransferase 5 involved_in ISO (PMID:12138164) RGD PMID:12138164 NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653
JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1353793|PMID:10644753)
RGD PMID:10644753 PMID:21873635 MGI:1353793, RGD:13792537 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1353793|PMID:10644753)
RGD PMID:10644753 PMID:21873635 MGI:1353793, RGD:13792537 NCBI chr  X:130,966,547...131,261,629
Ensembl chr  X:130,968,385...131,261,492
JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 acts_upstream_of_or_within ISO (MGI:1353793|PMID:10644753) RGD PMID:10644753 MGI:1353793 NCBI chr15:96,281,502...97,000,804
Ensembl chr15:96,281,646...97,000,462
JBrowse link
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 involved_in ISO (PMID:17761672) RGD PMID:17761672 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 involved_in ISO (PMID:17761672) RGD PMID:17761672 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1934916 (MGI:2150438|PMID:11457822)
RGD PMID:11457822 PMID:21873635 MGI:2150438, RGD:13792537 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:3,563,358...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in IBA
ISO
PMID:21873635
(PMID:9915799)
RGD PMID:9915799 PMID:21873635 RGD:13792537 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:213,787,010...214,116,569
Ensembl chr 2:213,787,006...214,115,373
JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07030903.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Gpc1 glypican 1 involved_in ISO
ISS
IEA
(PMID:12732622)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12732622 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Hpse heparanase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12213822)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12213822 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO (PMID:15146460) RGD PMID:15146460 NCBI chr10:104,596,810...104,613,510 JBrowse link
heparan sulfate proteoglycan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sulf1 sulfatase 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:5306289|PMID:18687675)
PMID:21873635
GO_REF:0000104
(PMID:18687675), (PMID:19666466), (PMID:19822709)
UniProt
RGD
PMID:18687675 PMID:19666466 PMID:19822709 PMID:21873635 GO_REF:0000024 GO_REF:0000104 MGI:5306289, RGD:13792537 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sulf2 sulfatase 2 involved_in ISO
IBA
(PMID:18687675)
(MGI:5306289|PMID:18687675)
PMID:21873635
RGD PMID:18687675 PMID:21873635 MGI:5306289, RGD:13792537 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07060833.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:94,944,360...94,981,873 JBrowse link
G Bgn biglycan acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3807344|PMID:18757743)
Ensembl
RGD
PMID:18757743 GO_REF:0000107 MGI:3807344 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
JBrowse link
G Mamdc2 MAM domain containing 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354
JBrowse link
G Ndnf neuron-derived neurotrophic factor acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr 4:94,944,749...94,987,414 JBrowse link
G Prss34 protease, serine, 34 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:14,315,913...14,317,712
Ensembl chr10:14,315,955...14,317,712
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr20:28,036,909...28,064,272
Ensembl chr20:28,033,475...28,064,272
JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 acts_upstream_of_or_within ISO (MGI:3807344|PMID:18757743) RGD PMID:18757743 MGI:3807344 NCBI chr16:26,382,895...26,815,943
Ensembl chr16:26,383,383...26,815,205
JBrowse link
positive regulation of heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS
(PMID:15853773)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15853773 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24425863)
UniProt
RGD
PMID:24425863 GO_REF:0000024 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:15853773) RGD PMID:15853773 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
positive regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856465 (MGI:2664273|PMID:3070812)
Ensembl
RGD
PMID:3070812 GO_REF:0000107 MGI:2664273 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 involved_in ISO (PMID:29443383) RGD PMID:29443383 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:9,018,514...9,027,591
Ensembl chr17:9,018,935...9,027,573
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Cant1 calcium activated nucleotidase 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:22539336)
UniProt
RGD
PMID:22539336 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:41,092,805...41,122,737
Ensembl chr 9:41,092,808...41,122,503
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:14,110,631...14,129,099
Ensembl chr12:14,110,393...14,129,057
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:122,824,712...122,837,935
Ensembl chr 4:122,824,022...122,838,019
JBrowse link
G Chst8 carbohydrate sulfotransferase 8 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1928003|PMID:10988300)
(PMID:10988300)
RGD PMID:10988300 PMID:21873635 MGI:1928003, RGD:13792537 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
JBrowse link
G Chst9 carbohydrate sulfotransferase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:11788602) RGD PMID:11788602 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:4946896|PMID:21185280) RGD PMID:21185280 MGI:4946896 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fam20b FAM20B, glycosaminoglycan xylosylkinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:68,801,663...68,839,979
Ensembl chr13:68,801,669...68,839,915
JBrowse link
G Foxl1 forkhead box L1 acts_upstream_of_or_within ISO MGI:2178230 (MGI:2153304|PMID:11555641) RGD PMID:11555641 MGI:2153304 NCBI chr19:49,196,255...49,200,682
Ensembl chr19:49,197,400...49,198,425
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
(PMID:12746903), (PMID:9564845)
GO_REF:0000107
RGD
Ensembl
PMID:9564845 PMID:12746903 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IMP
ISS
ISO
GO_REF:0000024
(PMID:11087729)
UniProt
RGD
PMID:11087729 PMID:19001053 GO_REF:0000024, RGD:2313142 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Xylt2 xylosyltransferase 2 acts_upstream_of_or_within ISO MGI:3714171 (MGI:3713963|PMID:17517600) RGD PMID:17517600 MGI:3713963 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
regulation of heparan sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:28404855) RGD PMID:28404855 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular metabolic process 10719
        cellular macromolecule metabolic process 8208
          glycoprotein metabolic process 363
            proteoglycan metabolic process 80
              cell wall proteoglycan metabolic process + 0
              chondroitin sulfate proteoglycan metabolic process + 36
              dermatan sulfate proteoglycan metabolic process + 7
              heparan sulfate proteoglycan metabolic process + 29
              proteoglycan biosynthetic process + 54
              proteoglycan catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        macromolecule metabolic process 9812
          protein metabolic process 5935
            glycoprotein metabolic process 363
              proteoglycan metabolic process 80
                cell wall proteoglycan metabolic process + 0
                chondroitin sulfate proteoglycan metabolic process + 36
                dermatan sulfate proteoglycan metabolic process + 7
                heparan sulfate proteoglycan metabolic process + 29
                proteoglycan biosynthetic process + 54
                proteoglycan catabolic process + 5
paths to the root