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ONTOLOGY REPORT - ANNOTATIONS


Term:chondroitin sulfate proteoglycan biosynthetic process
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Accession:GO:0050650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
Synonyms:exact_synonym: chondroitin sulfate proteoglycan anabolism;   chondroitin sulfate proteoglycan biosynthesis;   chondroitin sulfate proteoglycan formation;   chondroitin sulfate proteoglycan synthesis;   chondroitin sulphate proteoglycan biosynthesis;   chondroitin sulphate proteoglycan biosynthetic process


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chondroitin sulfate proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat1 beta-1,3-glucuronyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:27,777,024...27,804,368
Ensembl chr 8:27,777,179...27,804,515
JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:29,984,077...30,068,649
Ensembl chr 9:29,984,077...30,068,649
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 involved_in IBA
ISO
PMID:21873635
(PMID:25893793)
RGD PMID:25893793, PMID:21873635 RGD:13792537 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:11788602)
MGI:1927166 (MGI:4941099|PMID:21138417)
RGD PMID:11788602 PMID:21138417 MGI:4941099 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044
JBrowse link
G Cytl1 cytokine like 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr14:77,805,137...77,810,147
Ensembl chr14:77,805,130...77,810,147
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (MGI:3758399|PMID:17644814) RGD PMID:17644814 MGI:3758399 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 involved_in ISO
ISS
IBA
(PMID:24425863)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:24425863, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:104,724,728...104,790,639
Ensembl chr 8:104,724,743...104,790,639
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IBA
IEA
ISS
ISO
PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:17189265)
Ensembl
UniProt
RGD
PMID:17189265, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in ISO
IBA
ISS
IEA
(PMID:17189265), (PMID:26027496)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17189265 PMID:26027496, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485
JBrowse link
chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032202.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr18:54,206,651...54,207,523 JBrowse link
G Chpf chondroitin polymerizing factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2681120|MGI:5464019 (MGI:5462280|PMID:22952873), (MGI:5462286|PMID:22952769)
(PMID:12761225)
RGD PMID:12761225 PMID:22952769 PMID:22952873, PMID:21873635 MGI:5462280 MGI:5462286, RGD:13792537 NCBI chr 9:82,669,199...82,673,898
Ensembl chr 9:82,669,204...82,673,898
JBrowse link
G Chpf2 chondroitin polymerizing factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:7,108,461...7,113,940
Ensembl chr 4:7,108,462...7,113,919
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
ISO (PMID:11056388)
MGI:1926002 (MGI:1354846|PMID:10722746), (MGI:4941099|PMID:21138417)
RGD PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716
JBrowse link
G Chst12 carbohydrate sulfotransferase 12 involved_in ISO (PMID:10781601) RGD PMID:10781601 NCBI chr12:16,199,975...16,218,404
Ensembl chr12:16,200,019...16,201,632
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 involved_in ISO (PMID:12080076) RGD PMID:12080076 NCBI chr 4:122,223,846...122,244,848
Ensembl chr 4:122,224,535...122,237,754
JBrowse link
G Chst3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:2176247 (MGI:1206144|PMID:9597547), (MGI:2156294|PMID:11696535)
GO_REF:0000107
(PMID:9883891)
RGD
Ensembl
PMID:9597547 PMID:9883891 PMID:11696535, PMID:21873635 GO_REF:0000107 MGI:1206144 MGI:2156294, RGD:13792537 NCBI chr20:29,731,828...29,768,656
Ensembl chr20:29,731,816...29,738,506
JBrowse link
G Chst7 carbohydrate sulfotransferase 7 involved_in IBA
ISO
PMID:21873635
(PMID:10781596)
RGD PMID:10781596, PMID:21873635 RGD:13792537 NCBI chr  X:2,623,018...2,657,155
Ensembl chr  X:2,623,024...2,657,155
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:106576 (MGI:5462286|PMID:22952769)
RGD PMID:22952769, PMID:21873635 MGI:5462286, RGD:13792537 NCBI chr 1:127,010,587...127,071,570
Ensembl chr 1:127,010,588...127,071,570
JBrowse link
G Chsy3 chondroitin sulfate synthase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:54,243,626...54,497,475
Ensembl chr18:54,243,949...54,496,585
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO
IBA
(PMID:11514575), (PMID:12163485)
PMID:21873635
RGD PMID:11514575 PMID:12163485, PMID:21873635 RGD:13792537 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:150,148,626...150,185,062
Ensembl chr 4:150,153,844...150,185,044
JBrowse link
G Slc35d1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO MGI:3774133 (MGI:3771453|PMID:17952091) RGD PMID:17952091 MGI:3771453 NCBI chr 5:122,700,396...122,746,815
Ensembl chr 5:122,699,587...122,746,839
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2675908|PMID:14505572)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14505572 GO_REF:0000024 GO_REF:0000107 MGI:2675908 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Xylt1 xylosyltransferase 1 involved_in IEA
ISO
GO_REF:0000041
(MGI:5544658|PMID:24161523)
UniProt
RGD
PMID:24161523 GO_REF:0000041 MGI:5544658 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:82,386,003...82,399,485
Ensembl chr10:82,386,005...82,399,485
JBrowse link
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in ISO (PMID:12163485) RGD PMID:12163485 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      primary metabolic process 10642
        protein metabolic process 5988
          glycoprotein metabolic process 361
            proteoglycan metabolic process 78
              proteoglycan biosynthetic process 52
                chondroitin sulfate proteoglycan biosynthetic process 22
                  chondroitin sulfate biosynthetic process 16
                  chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      organic substance metabolic process 11420
        macromolecule metabolic process 9869
          cellular macromolecule metabolic process 8319
            cellular macromolecule biosynthetic process 5038
              glycoprotein biosynthetic process 293
                proteoglycan biosynthetic process 52
                  chondroitin sulfate proteoglycan biosynthetic process 22
                    chondroitin sulfate biosynthetic process 16
                    chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1
paths to the root