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ONTOLOGY REPORT - ANNOTATIONS

Term:brain morphogenesis
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Accession:GO:0048854 term browser browse the term
Definition:The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).


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brain morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFDN afadin, adherens junction formation factor acts_upstream_of_or_within ISO (PMID:25100583) MGI PMID:25100583 NCBI chr 6:167,826,564...167,972,023
Ensembl chr 6:167,826,893...167,972,023 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15713641) Ensembl
MGI		 PMID:15713641 GO_REF:0000107 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079 		JBrowse link
G BBS1 Bardet-Biedl syndrome 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18032602) Ensembl
MGI		 PMID:18032602 GO_REF:0000107 NCBI chr11:66,510,635...66,533,598
Ensembl chr11:66,510,606...66,533,613 		JBrowse link
G BBS2 Bardet-Biedl syndrome 2 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:18032602) BHF-UCL
MGI
Ensembl		 PMID:18032602 GO_REF:0000024 GO_REF:0000107 NCBI chr16:56,470,403...56,520,024
Ensembl chr16:56,465,640...56,582,667 		JBrowse link
G BBS4 Bardet-Biedl syndrome 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:18032602) Ensembl
MGI
BHF-UCL		 PMID:18032602 GO_REF:0000024 GO_REF:0000107 NCBI chr15:72,686,207...72,738,473
Ensembl chr15:72,686,179...72,738,475 		JBrowse link
G CDH2 cadherin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100583) Ensembl
MGI		 PMID:25100583 GO_REF:0000107 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CTNNA2 catenin alpha 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:79,185,377...80,648,780
Ensembl chr 2:79,185,231...80,648,861 		JBrowse link
G EMX1 empty spiracles homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23178126)
(PMID:25100583)		 Ensembl
MGI		 PMID:23178126 PMID:25100583 GO_REF:0000107 NCBI chr 2:72,916,189...72,934,891
Ensembl chr 2:72,916,260...72,936,071 		JBrowse link
G FANCC FA complementation group C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24483844) Ensembl
MGI		 PMID:24483844 GO_REF:0000107 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G FANCD2 FA complementation group D2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24483844) Ensembl
MGI		 PMID:24483844 GO_REF:0000107 NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932 		JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:171,861,549...172,006,638
Ensembl chr 5:171,861,549...172,006,873 		JBrowse link
G FOXO3 forkhead box O3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24483844) Ensembl
MGI		 PMID:24483844 GO_REF:0000107 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17954912) Ensembl
MGI		 PMID:17954912 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G MIR124-1 microRNA 124-1 acts_upstream_of_or_within ISO (PMID:21857657) MGI PMID:21857657 NCBI chr 8:9,903,388...9,903,472
Ensembl chr 8:9,903,388...9,903,472 		JBrowse link
G MKKS MKKS centrosomal shuttling protein involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:18032602) Ensembl
MGI
BHF-UCL		 PMID:18032602 GO_REF:0000024 GO_REF:0000107 NCBI chr20:10,401,009...10,434,222
Ensembl chr20:10,401,009...10,434,222 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:30503862) MGI PMID:30503862 NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,475...13,098,796 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 involved_in IMP
IBA		 (PMID:9063735) BHF-UCL
GO_Central		 PMID:9063735 GO_REF:0000033 NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,210...2,685,615 		JBrowse link
G PAX2 paired box 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944 		JBrowse link
G PCNT pericentrin acts_upstream_of_or_within ISO (PMID:20096683) MGI PMID:20096683 NCBI chr21:46,324,156...46,445,769
Ensembl chr21:46,324,124...46,445,769 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17614943) Ensembl
MGI		 PMID:17614943 GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17614943) MGI PMID:17614943 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (MGI:3832995|PMID:19208814) CACAO PMID:19208814 MGI:3832995 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212 		JBrowse link
G SLC4A10 solute carrier family 4 member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18165320) Ensembl
MGI		 PMID:18165320 GO_REF:0000107 NCBI chr 2:161,624,416...161,985,270
Ensembl chr 2:161,424,332...161,985,282 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
G SPEF2 sperm flagellar 2 acts_upstream_of_or_within ISS UniProt GO_REF:0000024 NCBI chr 5:35,617,863...35,814,611
Ensembl chr 5:35,617,844...35,814,611 		JBrowse link
G VPS51 VPS51 subunit of GARP complex involved_in IDA (PMID:30624672), (PMID:31207318) UniProt PMID:30624672 PMID:31207318 NCBI chr11:65,096,214...65,111,862
Ensembl chr11:65,089,324...65,111,862 		JBrowse link
G ZNF335 zinc finger protein 335 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23178126) Ensembl
MGI		 PMID:23178126 GO_REF:0000107 NCBI chr20:45,948,660...45,972,203
Ensembl chr20:45,948,660...45,972,203 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17440044) Ensembl
MGI		 PMID:17440044 GO_REF:0000107 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
diencephalon morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTX1 orthodenticle homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20816794) Ensembl
MGI		 PMID:20816794 GO_REF:0000107 NCBI chr 2:63,049,735...63,057,831
Ensembl chr 2:63,050,057...63,057,836 		JBrowse link
G OTX2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO (PMID:20816794) MGI PMID:20816794 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:15240551) MGI PMID:15240551 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
forebrain morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16613831) Ensembl
MGI		 PMID:16613831 GO_REF:0000107 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
G GAK cyclin G associated kinase acts_upstream_of_or_within ISO (PMID:18434600) MGI PMID:18434600 NCBI chr 4:849,277...932,316
Ensembl chr 4:849,276...932,373 		JBrowse link
G GDF7 growth differentiation factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10693795) Ensembl
MGI		 PMID:10693795 GO_REF:0000107 NCBI chr 2:20,667,144...20,679,243
Ensembl chr 2:20,667,144...20,679,243 		JBrowse link
G GSX2 GS homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9398437) Ensembl
MGI		 PMID:9398437 GO_REF:0000107 NCBI chr 4:54,100,163...54,102,498
Ensembl chr 4:54,099,523...54,102,498 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10882526), (PMID:9620767) Ensembl
MGI		 PMID:9620767 PMID:10882526 GO_REF:0000107 NCBI chr 3:57,197,838...57,227,615
Ensembl chr 3:57,197,838...57,227,606 		JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (PMID:21445260) MGI PMID:21445260 NCBI chr10:92,689,955...92,695,647
Ensembl chr10:92,689,955...92,695,647 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:19036983) MGI PMID:19036983 NCBI chr13:20,567,157...20,691,444
Ensembl chr13:20,567,138...20,691,444 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:11297510) Ensembl
MGI
HGNC-UCL		 PMID:11297510 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G SLIT1 slit guidance ligand 1 involved_in NAS (PMID:9813312) UniProt PMID:9813312 NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G TUBA1A tubulin alpha 1a involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,080 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:193,012,254...193,060,076
Ensembl chr 1:193,012,250...193,060,080 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16678101) Ensembl
MGI		 PMID:16678101 GO_REF:0000107 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15037319) Ensembl
MGI		 PMID:15037319 GO_REF:0000107 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
midbrain morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD3 frizzled class receptor 3 involved_in TAS (PMID:24431302) ParkinsonsUK-UCL PMID:24431302 NCBI chr 8:28,494,212...28,574,258
Ensembl chr 8:28,494,205...28,574,267 		JBrowse link
G FZD6 frizzled class receptor 6 involved_in TAS (PMID:24431302) ParkinsonsUK-UCL PMID:24431302 NCBI chr 8:103,298,494...103,332,866
Ensembl chr 8:103,298,433...103,332,866 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9030684) Ensembl
MGI		 PMID:9030684 GO_REF:0000107 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    developmental process 7618
      anatomical structure morphogenesis 3195
        animal organ morphogenesis 1242
          brain morphogenesis 49
            forebrain morphogenesis + 19
            midbrain morphogenesis 3
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7618
      anatomical structure development 7029
        multicellular organism development 5641
          system development 4919
            nervous system development 3058
              central nervous system development 1302
                brain development 950
                  brain morphogenesis 49
                    forebrain morphogenesis + 19
                    midbrain morphogenesis 3
paths to the root