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Gene: SPEF2 (sperm flagellar 2) Homo sapiens
Symbol: SPEF2
Name: sperm flagellar 2
Description: Predicted to be involved in several processes, including animal organ morphogenesis; epithelial cilium movement involved in extracellular fluid movement; and sperm axoneme assembly. Predicted to localize to Golgi apparatus; manchette; and sperm midpiece. Implicated in male infertility; INTERACTS WITH amiodarone; antirheumatic drug; butanal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cancer/testis antigen 122; CT122; FLJ23164; FLJ23577; FLJ25395; KIAA1770; KPL2; MGC102842; sperm flagellar protein 2; SPGF43; testis tissue sperm-binding protein Li 47a
Mus musculus (house mouse) : Spef2 (sperm flagellar 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spef2 (sperm flagellar 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spef2 (sperm flagellar 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPEF2 (sperm flagellar 2)
Canis lupus familiaris (dog) : SPEF2 (sperm flagellar 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spef2 (sperm flagellar 2)
Sus scrofa (pig) : SPEF2 (sperm flagellar 2)
Chlorocebus sabaeus (African green monkey) : SPEF2 (sperm flagellar 2)
Heterocephalus glaber (naked mole-rat) : Spef2 (sperm flagellar 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl535,617,844 - 35,814,611 (+)EnsemblGRCh38hg38GRCh38
GRCh38535,617,367 - 35,814,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37535,617,900 - 35,814,713 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36535,653,746 - 35,850,470 (+)NCBINCBI36hg18NCBI36
Celera535,500,093 - 35,700,401 (+)NCBI
Cytogenetic Map5p13.2NCBI
HuRef535,566,794 - 35,654,481 (+)ENTREZGENEHuRef
HuRef535,657,528 - 35,764,642 (+)NCBIHuRef
CHM1_1535,620,239 - 35,817,543 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SPEF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605340
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.