Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NFIX (nuclear factor I X) Homo sapiens
Symbol: NFIX
Name: nuclear factor I X
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Localizes to the nucleoplasm. Implicated in Marshall-Smith syndrome and Sotos syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; MRSHSS; NF-I/X; NF1-X; NF1A; NFI-X; nuclear factor 1 X-type; nuclear factor 1/X; nuclear factor i/x; nuclear factor I/X (CCAAT-binding transcription factor); SOTOS2; TGGCA-binding protein
Mus musculus (house mouse) : Nfix (nuclear factor I/X)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfix (nuclear factor I X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfix (nuclear factor I X)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIX (nuclear factor I X)
Canis lupus familiaris (dog) : NFIX (nuclear factor I X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfix (nuclear factor I X)
Sus scrofa (pig) : NFIX (nuclear factor I X)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381912,995,475 - 13,098,796 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,106,584 - 13,209,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,967,584 - 13,070,610 (+)NCBINCBI36hg18NCBI36
Build 341912,967,583 - 13,070,610NCBI
Celera1912,996,993 - 13,100,014 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,707,303 - 12,782,249 (+)NCBIHuRef
CHM1_11913,107,626 - 13,210,624 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NFIX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69161
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.