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Gene: NFIX (nuclear factor I X) Homo sapiens
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Symbol: NFIX
Name: nuclear factor I X
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Localizes to the nucleoplasm. Implicated in Marshall-Smith syndrome and Sotos syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; MRSHSS; NF-I/X; NF1-X; NF1A; NFI-X; nuclear factor 1 X-type; nuclear factor 1/X; nuclear factor i/x; nuclear factor I/X (CCAAT-binding transcription factor); SOTOS2; TGGCA-binding protein
Orthologs:
Mus musculus (house mouse) : Nfix (nuclear factor I/X)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfix (nuclear factor I X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfix (nuclear factor I X)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIX (nuclear factor I X)
Canis lupus familiaris (dog) : NFIX (nuclear factor I X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfix (nuclear factor I X)
Sus scrofa (pig) : NFIX (nuclear factor I X)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,995,475 - 13,098,796 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,106,584 - 13,209,610 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,967,584 - 13,070,610 (+)NCBINCBI36hg18NCBI36
Build 341912,967,583 - 13,070,610NCBI
Celera1912,996,993 - 13,100,014 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,707,303 - 12,782,249 (+)NCBIHuRef
CHM1_11913,107,626 - 13,210,624 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NFIX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69161
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.