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ONTOLOGY REPORT - ANNOTATIONS

Term:programmed cell death in response to reactive oxygen species
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Accession:GO:0097468 term browser browse the term
Definition:Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
Synonyms:exact_synonym: PCD in response to reactive oxygen species;   reactive oxygen species-mediated PCD;   reactive oxygen species-mediated programmed cell death
 broad_synonym: PCD in response to oxidative stress;   programmed cell death in response to oxidative stress


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programmed cell death in response to reactive oxygen species term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:22651868) RGD PMID:22651868 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Pjvk pejvakin involved_in ISO (PMID:30936319) RGD PMID:30936319 NCBI chr 3:61,594,644...61,605,051
Ensembl chr 3:61,596,641...61,605,045 		JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k4 mitogen activated protein kinase kinase 4 involved_in ISO (PMID:24705900) RGD PMID:24705900 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA		 UniProtKB:O00506 (PMID:22652780)
GO_REF:0000107		 RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO UniProtKB:Q9BUL8 (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:32412792 RGD:150429761 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Glrx glutaredoxin IMP RGD PMID:19938943 RGD:9686063 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hk3 hexokinase 3 involved_in IDA PMID:21072205 CACAO PMID:21072205 RGD:10047370 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir132 microRNA 132 IMP RGD PMID:23585551 RGD:7327146 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir21 microRNA 21 IMP RGD PMID:19336275 RGD:41404719 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir212 microRNA 212 IMP RGD PMID:23585551 RGD:7327146 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mirlet7b microRNA let-7b involved_in ISO (PMID:26296645) RGD PMID:26296645 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010) RGD PMID:24947010 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP		 (PMID:17579517) RGD PMID:17579517 PMID:17579517 RGD:8693356 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010)		 Ensembl
RGD		 PMID:24947010 GO_REF:0000107 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
positive regulation of hydrogen peroxide-mediated programmed cell death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G IMP RGD PMID:20594982 RGD:9685387 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:23585551 RGD:7327146 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Foxa1 forkhead box A1 IMP RGD PMID:19649697 RGD:151665511 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxo3 forkhead box O3 IMP RGD PMID:23585551 RGD:7327146 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxp1 forkhead box P1 IMP cardiac muscle cell RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Pawr pro-apoptotic WT1 regulator involved_in ISO (PMID:25472717) RGD PMID:25472717 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cell death 2190
        programmed cell death 2190
          programmed cell death in response to reactive oxygen species 24
            hydrogen peroxide-mediated programmed cell death + 22
            singlet oxygen-mediated programmed cell death 0
Path 2
Term Annotations click to browse term
  biological_process 20069
    response to stimulus 10792
      cellular response to stimulus 8813
        cellular response to stress 2016
          cellular response to chemical stress 402
            cellular response to oxidative stress 315
              cellular response to reactive oxygen species 204
                programmed cell death in response to reactive oxygen species 24
                  hydrogen peroxide-mediated programmed cell death + 22
                  singlet oxygen-mediated programmed cell death 0
paths to the root