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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to acidic pH
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Accession:GO:0071468 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
Comment:This term should be used to annotate instances where a cell is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0071229 'cellular response to acid chemical'.
Synonyms:broad_synonym: cellular response to acidity


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cellular response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577 JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:106,536,009...106,571,255 JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IEP RGD PMID:26033523 RGD:13204712 NCBI chr 1:22,518,051...22,583,044 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:8458414 RGD:7243874 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 involved_in IDA PMID:22948150 UniProt PMID:22948150 RGD:408345197 NCBI chr19:53,959,411...53,997,726 JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 involved_in ISO (PMID:22948150) RGD PMID:22948150 NCBI chr 6:25,761,487...25,799,153 JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26919430)		 UniProt
RGD		 PMID:26919430 GO_REF:0000024 NCBI chr 1:204,117,941...204,129,494 JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 involved_in ISO (PMID:22948150), (PMID:38630723) RGD PMID:22948150 PMID:38630723 NCBI chr 7:104,429,186...104,473,924 JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting NOT|involved_in ISO (PMID:20605874)
(PMID:16891422)		 RGD PMID:16891422 PMID:20605874 NCBI chr19:37,585,564...37,650,083 JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (PMID:16891422), (PMID:29567962) RGD PMID:16891422 PMID:29567962 NCBI chr 1:243,032,891...243,070,031 JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO
ISS		 (PMID:20717956)
GO_REF:0000024		 RGD
UniProt		 PMID:20717956 GO_REF:0000024 NCBI chr 7:14,521,448...14,534,589 JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:20717956) RGD PMID:20717956 NCBI chr 4:117,871,301...117,908,819 JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 4:158,122,962...158,146,184 JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:176,430,063...176,484,451 JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma involved_in ISO
IEA		 (PMID:16423824)
GO_REF:0000107		 RGD
Ensembl		 PMID:16423824 GO_REF:0000107 NCBI chr 1:176,304,942...176,338,816 JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24840010)		 UniProt
RGD		 PMID:24840010 GO_REF:0000024 NCBI chr 5:145,576,341...145,629,630 JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA		 (PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:57,851,428...57,876,513 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    response to stimulus 11014
      response to abiotic stimulus 1597
        response to pH 58
          response to acidic pH 33
            cellular response to acidic pH 17
              cellular stress response to acidic pH 0
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular response to stimulus 8916
        cellular response to environmental stimulus 449
          cellular response to abiotic stimulus 449
            cellular response to pH 28
              cellular response to acidic pH 17
                cellular stress response to acidic pH 0
paths to the root