ONTOLOGY REPORT - ANNOTATIONS
Term: chromosome separation
Accession: GO:0051304
browse the term
Definition: The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
Synonyms: narrow_synonym: rDNA separation
related_synonym: chromatid release
alt_id: GO:0034500
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Cenatac
centrosomal AT-AC splicing factor
involved_in
ISO
(PMID:34009673)
UniProt
PMID:34009673
NCBI chrNW_004624784:14,395,330...14,407,122
Ensembl chrNW_004624784:14,394,981...14,407,122
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Recql5
RecQ like helicase 5
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624801:5,530,411...5,568,355
Ensembl chrNW_004624801:5,530,992...5,567,628
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Smarcad1
SNF2 related chromatin remodeling ATPase with DExD box 1
involved_in
ISO
(PMID:21549307)
UniProt
PMID:21549307
NCBI chrNW_004624757:22,038,421...22,103,266
Ensembl chrNW_004624757:22,038,542...22,103,960
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Top3a
DNA topoisomerase III alpha
involved_in
ISO
(PMID:30057030)
UniProt
PMID:30057030
NCBI chrNW_004624849:3,159,432...3,196,235
Ensembl chrNW_004624849:3,159,810...3,194,860
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Mad1l1
mitotic arrest deficient 1 like 1
involved_in
ISO
(PMID:19010891)
UniProt
PMID:19010891
NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492
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Mad2l1bp
MAD2L1 binding protein
involved_in
ISO
(PMID:18022368)
UniProt
PMID:18022368
NCBI chrNW_004624754:16,044,275...16,047,500
Ensembl chrNW_004624754:16,045,331...16,047,497
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Prap1
proline rich acidic protein 1
involved_in
ISO
(PMID:24374861)
UniProt
PMID:24374861
NCBI chrNW_004624737:13,346,621...13,350,428
Ensembl chrNW_004624737:13,343,674...13,351,284
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Ncaph
non-SMC condensin I complex subunit H
involved_in
ISO
(PMID:25961503)
MGI
PMID:25961503
NCBI chrNW_004624749:2,411,952...2,439,981
Ensembl chrNW_004624749:2,411,970...2,444,446
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Ncaph2
non-SMC condensin II complex subunit H2
involved_in
ISO
(PMID:25961503)
MGI
PMID:25961503
NCBI chrNW_004624752:257,885...268,971
Ensembl chrNW_004624752:258,039...268,737
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M1ap
meiosis 1 associated protein
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624749:28,855,225...28,955,378
Ensembl chrNW_004624749:28,871,031...28,956,045
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Espl1
extra spindle pole bodies like 1, separase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624904:1,305,040...1,330,505
Ensembl chrNW_004624904:1,305,000...1,330,761
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Ncapd3
non-SMC condensin II complex subunit D3
acts_upstream_of_or_within
ISO
(PMID:21795393)
MGI
PMID:21795393
NCBI chrNW_004624812:8,708,061...8,782,282
Ensembl chrNW_004624812:8,709,735...8,782,200
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Ttk
TTK protein kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:21558374)
TreeGrafter MGI
PMID:21558374
GO_REF:0000118
NCBI chrNW_004624819:6,631,697...6,682,181
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Chfr
checkpoint with forkhead and ring finger domains
involved_in
ISO
(PMID:10935642)
UniProt
PMID:10935642
NCBI chrNW_004624747:28,187,356...28,222,041
Ensembl chrNW_004624747:28,188,419...28,221,525
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Dis3l2
DIS3 like 3'-5' exoribonuclease 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624843:4,900,810...5,196,827
Ensembl chrNW_004624843:4,901,316...5,196,827
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LOC101715712
inactive serine/threonine-protein kinase TEX14
involved_in
IEA
TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004624871:578,323...679,120
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Ncaph2
non-SMC condensin II complex subunit H2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624752:257,885...268,971
Ensembl chrNW_004624752:258,039...268,737
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Ppp2r1a
protein phosphatase 2 scaffold subunit Aalpha
acts_upstream_of_or_within
ISO
(PMID:24899574)
MGI
PMID:24899574
NCBI chrNW_004624832:2,979,270...3,009,189
Ensembl chrNW_004624832:2,979,320...3,011,715
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Apc
APC regulator of WNT signaling pathway
acts_upstream_of_or_within
ISO
(PMID:17227893)
MGI
PMID:17227893
NCBI chrNW_004624743:30,517,034...30,635,740
Ensembl chrNW_004624743:30,546,323...30,635,737
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Atm
ATM serine/threonine kinase
involved_in
ISO
(PMID:11943150)
UniProt
PMID:11943150
NCBI chrNW_004624784:2,933,172...3,080,131
Ensembl chrNW_004624784:2,937,499...3,078,216
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Birc5
baculoviral IAP repeat containing 5
involved_in
ISO
(PMID:12805209)
UniProt
PMID:12805209
NCBI chrNW_004624801:7,727,084...7,735,946
Ensembl chrNW_004624801:7,727,093...7,735,940
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
involved_in
IEA
TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004624749:1,584,289...1,639,334
Ensembl chrNW_004624749:1,584,186...1,639,770
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624804:7,477,046...7,533,322
Ensembl chrNW_004624804:7,492,799...7,533,408
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Cenpe
centromere protein E
involved_in
ISO
(PMID:12925705)
UniProt
PMID:12925705
NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076
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Haspin
histone H3 associated protein kinase
involved_in
ISO
(PMID:23071153)
UniProt
PMID:23071153
NCBI chrNW_004624786:6,371,639...6,374,517
Ensembl chrNW_004624786:6,371,874...6,374,195
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Ik
IK cytokine
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624743:33,400,359...33,413,993
Ensembl chrNW_004624743:33,400,459...33,413,993
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Klhl22
kelch like family member 22
involved_in
ISO
(PMID:23455478)
UniProt
PMID:23455478
NCBI chrNW_004624945:409,093...446,619
Ensembl chrNW_004624945:408,999...441,975
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Kntc1
kinetochore associated 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624747:22,667,872...22,758,411
Ensembl chrNW_004624747:22,669,297...22,758,226
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LOC101715712
inactive serine/threonine-protein kinase TEX14
involved_in
IEA
TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004624871:578,323...679,120
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Mad1l1
mitotic arrest deficient 1 like 1
involved_in
IEA
TreeGrafter InterPro Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492
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Plk1
polo like kinase 1
involved_in
ISO
(PMID:23455478)
UniProt
PMID:23455478
NCBI chrNW_004624782:8,811,593...8,823,060
Ensembl chrNW_004624782:8,811,616...8,826,749
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Psmg2
proteasome assembly chaperone 2
acts_upstream_of_or_within
ISO
(PMID:12147697)
MGI
PMID:12147697
NCBI chrNW_004624770:19,787,876...19,802,623
Ensembl chrNW_004624770:19,788,057...19,802,422
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Spdl1
spindle apparatus coiled-coil protein 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chrNW_004624733:20,326,565...20,350,937
Ensembl chrNW_004624733:20,326,893...20,350,923
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Tpr
translocated promoter region, nuclear basket protein
involved_in
ISO
(PMID:20133940)
UniProt
PMID:20133940
NCBI chrNW_004624814:7,249,379...7,306,239
Ensembl chrNW_004624814:7,249,278...7,306,235
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Trip13
thyroid hormone receptor interactor 13
involved_in
ISO
(PMID:28553959)
UniProt
PMID:28553959
NCBI chrNW_004624751:439,195...459,033
Ensembl chrNW_004624751:439,119...459,080
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Ttk
TTK protein kinase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624819:6,631,697...6,682,181
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Znf207
zinc finger protein 207
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624875:434,770...463,977
Ensembl chrNW_004624875:434,087...453,932
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Zw10
zw10 kinetochore protein
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624784:9,221,123...9,255,294
Ensembl chrNW_004624784:9,221,128...9,255,284
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Zwilch
zwilch kinetochore protein
involved_in
IEA
TreeGrafter UniProt
GO_REF:0000104 GO_REF:0000118
NCBI chrNW_004624781:6,168,482...6,209,581
Ensembl chrNW_004624781:6,171,114...6,209,380
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Zwint
ZW10 interacting kinetochore protein
involved_in
ISO
(PMID:15485811)
HGNC-UCL
PMID:15485811
NCBI chrNW_004624791:7,528,452...7,534,182
Ensembl chrNW_004624791:7,528,426...7,534,553
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Mos
MOS proto-oncogene, serine/threonine kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624886:3,934,081...3,935,341
Ensembl chrNW_004624886:3,934,192...3,935,220
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Fbxo5
F-box protein 5
involved_in
ISO
(PMID:11988738), (PMID:16921029)
UniProt
PMID:11988738 PMID:16921029
NCBI chrNW_004624785:5,248,434...5,260,623
Ensembl chrNW_004624785:5,247,731...5,260,736
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Rad21
RAD21 cohesin complex component
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624763:15,131,106...15,157,512
Ensembl chrNW_004624763:15,131,005...15,158,155
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Usp44
ubiquitin specific peptidase 44
involved_in
ISO
(PMID:17443180)
UniProt
PMID:17443180
NCBI chrNW_004624750:11,697,919...11,725,421
Ensembl chrNW_004624750:11,710,218...11,724,529
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Ska1
spindle and kinetochore associated complex subunit 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624778:13,948,567...13,968,643
Ensembl chrNW_004624778:13,953,390...13,968,683
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Ska3
spindle and kinetochore associated complex subunit 3
involved_in
ISO
(PMID:19646878)
UniProt
PMID:19646878
NCBI chrNW_004624776:16,412,683...16,450,784
Ensembl chrNW_004624776:16,413,048...16,445,892
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Ncapd2
non-SMC condensin I complex subunit D2
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624860:3,229,091...3,256,631
Ensembl chrNW_004624860:3,230,577...3,256,407
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Ncapd3
non-SMC condensin II complex subunit D3
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624812:8,708,061...8,782,282
Ensembl chrNW_004624812:8,709,735...8,782,200
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Ncapg2
non-SMC condensin II complex subunit G2
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624800:432,307...494,361
Ensembl chrNW_004624800:432,258...498,718
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Ncaph
non-SMC condensin I complex subunit H
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624749:2,411,952...2,439,981
Ensembl chrNW_004624749:2,411,970...2,444,446
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Ncaph2
non-SMC condensin II complex subunit H2
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624752:257,885...268,971
Ensembl chrNW_004624752:258,039...268,737
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Numa1
nuclear mitotic apparatus protein 1
involved_in
ISO
(PMID:23921553)
UniProt
PMID:23921553
NCBI chrNW_004624817:4,896,066...4,963,440
Ensembl chrNW_004624817:4,924,827...4,963,436
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Smc2
structural maintenance of chromosomes 2
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624758:7,267,024...7,318,930
Ensembl chrNW_004624758:7,268,474...7,317,919
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Smc4
structural maintenance of chromosomes 4
involved_in
ISO
(PMID:21795393)
ComplexPortal
PMID:21795393
NCBI chrNW_004624730:38,145,101...38,178,788
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Knl1
kinetochore scaffold 1
involved_in
ISO
(PMID:35167144)
UniProt
PMID:35167144
NCBI chrNW_004624804:7,884,580...7,952,567
Ensembl chrNW_004624804:7,889,689...7,952,384
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Mapk15
mitogen-activated protein kinase 15
involved_in
ISO
(PMID:23351492)
UniProt
PMID:23351492
NCBI chrNW_004624735:13,049,509...13,077,509
Ensembl chrNW_004624735:13,047,125...13,056,308
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Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
involved_in
ISO
(PMID:19229290)
UniProt
PMID:19229290
NCBI chrNW_004624788:10,593,647...10,624,755
Ensembl chrNW_004624788:10,593,940...10,625,052
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Gen1
GEN1 Holliday junction 5' flap endonuclease
involved_in
ISO
(PMID:23108668)
UniProt
PMID:23108668
NCBI chrNW_004624738:689,835...718,549
Ensembl chrNW_004624738:696,080...718,240
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Mad1l1
mitotic arrest deficient 1 like 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492
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Ndc80
NDC80 kinetochore complex component
involved_in
ISO
(PMID:25743205)
UniProt
PMID:25743205
NCBI chrNW_004624770:12,937,887...12,974,352
Ensembl chrNW_004624770:12,939,763...12,974,162
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Pcid2
PCI domain containing 2
involved_in
ISO
(PMID:20870947)
UniProt
PMID:20870947
NCBI chrNW_004624793:722,743...744,824
Ensembl chrNW_004624793:722,762...744,743
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Tpr
translocated promoter region, nuclear basket protein
involved_in
ISO
(PMID:18981471), (PMID:19273613)
UniProt
PMID:18981471 PMID:19273613
NCBI chrNW_004624814:7,249,379...7,306,239
Ensembl chrNW_004624814:7,249,278...7,306,235
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Xrcc3
X-ray repair cross complementing 3
involved_in
ISO
(PMID:23108668)
UniProt
PMID:23108668
NCBI chrNW_004624734:1,216,641...1,223,860
Ensembl chrNW_004624734:1,217,549...1,223,280
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Anapc11
anaphase promoting complex subunit 11
involved_in
ISO
(PMID:11739784)
UniProt
PMID:11739784
NCBI chrNW_004624801:10,738,356...10,742,334
Ensembl chrNW_004624801:10,738,224...10,742,220
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Anapc5
anaphase promoting complex subunit 5
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624747:21,847,948...21,881,501
Ensembl chrNW_004624747:21,844,453...21,881,847
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Anapc7
anaphase promoting complex subunit 7
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624747:21,473,337...21,501,348
Ensembl chrNW_004624747:21,473,352...21,499,843
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Cdc20
cell division cycle 20
involved_in
ISO
(PMID:9637688)
UniProt
PMID:9637688
NCBI chrNW_004624892:2,675,980...2,679,709
Ensembl chrNW_004624892:2,675,754...2,679,793
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Cdc23
cell division cycle 23
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624743:31,012,262...31,036,639
Ensembl chrNW_004624743:31,012,720...31,036,762
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Cenpe
centromere protein E
involved_in
ISO
(PMID:12925705)
UniProt
PMID:12925705
NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076
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Cul3
cullin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624823:767,347...854,065
Ensembl chrNW_004624823:766,780...852,727
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Nsmce2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
involved_in
ISO
(PMID:19502785)
UniProt
PMID:19502785
NCBI chrNW_004624735:29,915,007...30,166,564
Ensembl chrNW_004624735:29,913,423...30,151,922
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Rb1
RB transcriptional corepressor 1
involved_in
ISO
(PMID:20551165)
BHF-UCL
PMID:20551165
NCBI chrNW_004624748:6,358,588...6,533,217
Ensembl chrNW_004624748:6,358,180...6,533,249
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Ube2c
ubiquitin conjugating enzyme E2 C
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624790:8,756,758...8,760,078
Ensembl chrNW_004624790:8,751,662...8,760,057
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Csnk2a1
casein kinase 2 alpha 1
involved_in
ISO
(PMID:11704824)
UniProt
PMID:11704824
NCBI chrNW_004624741:1,566,380...1,635,365
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Csnk2a2
casein kinase 2 alpha 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624746:28,012,543...28,064,610
Ensembl chrNW_004624746:28,012,556...28,060,413
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Zwint
ZW10 interacting kinetochore protein
involved_in
ISO
(PMID:26486467)
UniProt
PMID:26486467
NCBI chrNW_004624791:7,528,452...7,534,182
Ensembl chrNW_004624791:7,528,426...7,534,553
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Anapc15
anaphase promoting complex subunit 15
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chrNW_004624817:4,863,426...4,866,452
Ensembl chrNW_004624817:4,864,670...4,866,452
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Cdk5rap2
CDK5 regulatory subunit associated protein 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624760:14,736,273...14,930,168
Ensembl chrNW_004624760:14,736,104...14,930,119
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Knl1
kinetochore scaffold 1
involved_in
ISO
(PMID:19893618)
UniProt
PMID:19893618
NCBI chrNW_004624804:7,884,580...7,952,567
Ensembl chrNW_004624804:7,889,689...7,952,384
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Lcmt1
leucine carboxyl methyltransferase 1
acts_upstream_of_or_within
ISO
(PMID:17724024)
MGI
PMID:17724024
NCBI chrNW_004624782:9,974,415...10,043,475
Ensembl chrNW_004624782:9,979,433...10,043,475
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Prp4k
pre-mRNA processing factor kinase PRP4K
involved_in
ISO
(PMID:17998396)
UniProt
PMID:17998396
NCBI chrNW_004624756:21,038,438...21,082,607
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Usp44
ubiquitin specific peptidase 44
involved_in
ISO
(PMID:21853124)
UniProt
PMID:21853124
NCBI chrNW_004624750:11,697,919...11,725,421
Ensembl chrNW_004624750:11,710,218...11,724,529
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Tpr
translocated promoter region, nuclear basket protein
involved_in
ISO
(PMID:20133940)
UniProt
PMID:20133940
NCBI chrNW_004624814:7,249,379...7,306,239
Ensembl chrNW_004624814:7,249,278...7,306,235
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all