Ska1 (spindle and kinetochore associated complex subunit 1) - Rat Genome Database

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Gene: Ska1 (spindle and kinetochore associated complex subunit 1) Heterocephalus glaber
Analyze
Symbol: Ska1
Name: spindle and kinetochore associated complex subunit 1
RGD ID: 18908460
Description: ENCODES a protein that exhibits microtubule binding (inferred); INVOLVED IN establishment of meiotic spindle orientation (ortholog); spindle assembly involved in female meiosis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); intellectual disability (ortholog); FOUND IN kinetochore (ortholog); meiotic spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Spindle and kinetochore-associated protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477813,953,390 - 13,968,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477813,948,567 - 13,968,643 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ska1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477813,953,390 - 13,968,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477813,948,567 - 13,968,643 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SKA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381850,375,046 - 50,394,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1850,375,040 - 50,394,168 (+)EnsemblGRCh38hg38GRCh38
GRCh371847,901,416 - 47,920,538 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361846,155,390 - 46,174,536 (+)NCBINCBI36Build 36hg18NCBI36
Build 341846,155,400 - 46,174,534NCBI
Celera1844,757,915 - 44,777,060 (+)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1844,755,860 - 44,775,003 (+)NCBIHuRef
CHM1_11847,896,963 - 47,916,096 (+)NCBICHM1_1
T2T-CHM13v2.01850,576,800 - 50,595,915 (+)NCBIT2T-CHM13v2.0
Ska1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391874,328,370 - 74,340,889 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1874,328,370 - 74,340,889 (-)EnsemblGRCm39 Ensembl
GRCm381874,195,299 - 74,207,818 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1874,195,299 - 74,207,818 (-)EnsemblGRCm38mm10GRCm38
MGSCv371874,354,953 - 74,367,472 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361874,320,668 - 74,333,220 (-)NCBIMGSCv36mm8
Celera1875,425,305 - 75,437,850 (-)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1850.67NCBI
Ska1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,069,957 - 70,080,303 (-)NCBIGRCr8
mRatBN7.21867,794,722 - 67,805,037 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1867,794,725 - 67,805,037 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1869,902,907 - 69,913,217 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01870,577,344 - 70,587,637 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01868,443,383 - 68,453,679 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,174,316 - 70,184,368 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,173,944 - 70,184,337 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01869,317,012 - 69,327,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41870,988,118 - 70,998,430 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11871,061,315 - 71,071,569 (-)NCBI
Celera1865,976,023 - 65,986,335 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
Ska1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540235,382,412 - 35,395,814 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540235,382,531 - 35,395,787 (+)NCBIChiLan1.0ChiLan1.0
SKA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21767,892,960 - 67,911,063 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11853,585,562 - 53,603,666 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01843,745,560 - 43,764,452 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11847,093,106 - 47,111,996 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1847,093,115 - 47,111,996 (+)Ensemblpanpan1.1panPan2
SKA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1780,552,249 - 80,561,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl780,552,292 - 80,560,565 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha779,962,642 - 79,972,669 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0780,638,908 - 80,648,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl780,638,967 - 80,648,939 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1780,352,216 - 80,362,248 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0780,382,115 - 80,392,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0780,669,635 - 80,679,677 (+)NCBIUU_Cfam_GSD_1.0
Ska1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494437,538,531 - 37,554,979 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649712,777,334 - 12,794,032 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649712,777,454 - 12,793,992 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SKA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl199,976,485 - 99,993,462 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1199,976,354 - 99,993,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21109,665,390 - 109,732,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SKA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11830,562,320 - 30,579,966 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1830,560,284 - 30,579,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660504,702,946 - 4,722,276 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000017203   ⟹   ENSHGLP00000017032
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477813,953,390 - 13,968,683 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000017204   ⟹   ENSHGLP00000017033
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477813,953,390 - 13,968,683 (+)Ensembl
RefSeq Acc Id: XM_004855157   ⟹   XP_004855214
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477813,953,431 - 13,968,643 (+)NCBI
RefSeq Acc Id: XM_021236625   ⟹   XP_021092284
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477813,948,567 - 13,968,643 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855214 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092284 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13388 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017033
  ENSHGLP00100008234
GenBank Protein JAO01002 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021092284   ⟸   XM_021236625
- UniProtKB: G5BVS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855214   ⟸   XM_004855157
- UniProtKB: G5BVS7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000017033   ⟸   ENSHGLT00000017204
Ensembl Acc Id: ENSHGLP00000017032   ⟸   ENSHGLT00000017203


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012193 Ensembl, ENTREZGENE
  ENSHGLG00100006122 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017204 ENTREZGENE
  ENSHGLT00100008333 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1890 UniProtKB/TrEMBL
  6.10.250.1370 UniProtKB/TrEMBL
InterPro SKA1 UniProtKB/TrEMBL
  SKA1-MBD UniProtKB/TrEMBL
KEGG Report hgl:101699857 UniProtKB/TrEMBL
NCBI Gene Ska1 ENTREZGENE
PANTHER PTHR28573 UniProtKB/TrEMBL
  SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
Pfam SKA1 UniProtKB/TrEMBL
UniProt G5BVS7 ENTREZGENE, UniProtKB/TrEMBL