Dis3l2 (DIS3 like 3'-5' exoribonuclease 2) - Rat Genome Database

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Gene: Dis3l2 (DIS3 like 3'-5' exoribonuclease 2) Heterocephalus glaber
Analyze
Symbol: Dis3l2
Name: DIS3 like 3'-5' exoribonuclease 2
RGD ID: 18934739
Description: ENCODES a protein that exhibits 3'-5' exonuclease activity (inferred); 3'-5'-RNA exonuclease activity (inferred); exonuclease activity (inferred); INVOLVED IN cell division (inferred); miRNA catabolic process (inferred); mitotic cell cycle (inferred); ASSOCIATED WITH genetic disease (ortholog); hepatoblastoma (ortholog); Joubert syndrome 22 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); P-body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DIS3 mitotic control homolog (S. cerevisiae)-like 2; DIS3-like exonuclease 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248434,901,316 - 5,196,827 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248434,900,810 - 5,196,827 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dis3l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248434,901,316 - 5,196,827 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248434,900,810 - 5,196,827 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DIS3L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,961,713 - 232,344,350 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,961,245 - 232,344,350 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,826,423 - 233,209,060 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362232,534,537 - 232,910,152 (+)NCBINCBI36Build 36hg18NCBI36
Celera2226,589,534 - 226,966,072 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,677,041 - 225,059,431 (+)NCBIHuRef
CHM1_12232,832,242 - 233,214,871 (+)NCBICHM1_1
T2T-CHM13v2.02232,448,342 - 232,831,055 (+)NCBIT2T-CHM13v2.0
Dis3l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,629,646 - 86,977,819 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,631,530 - 86,977,817 (+)EnsemblGRCm39 Ensembl
GRCm38186,701,924 - 87,050,097 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,703,808 - 87,050,095 (+)EnsemblGRCm38mm10GRCm38
MGSCv37188,600,379 - 88,946,672 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36188,535,014 - 88,881,263 (+)NCBIMGSCv36mm8
Celera189,673,472 - 90,022,293 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.99NCBI
Dis3l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,802,056 - 95,184,523 (+)NCBIGRCr8
mRatBN7.2987,355,409 - 87,736,616 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,356,457 - 87,736,616 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx995,772,927 - 96,160,932 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,901,251 - 101,296,662 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,284,763 - 99,664,872 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,767,837 - 94,161,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,660,680 - 94,160,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0993,495,138 - 93,886,547 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,470,810 - 85,855,679 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera984,770,512 - 85,150,470 (+)NCBICelera
Cytogenetic Map9q35NCBI
Dis3l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,559,067 - 3,830,064 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554533,558,744 - 3,851,222 (-)NCBIChiLan1.0ChiLan1.0
DIS3L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213134,559,408 - 134,928,324 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B134,574,474 - 134,943,290 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B119,187,659 - 119,558,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B237,976,038 - 238,346,098 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B238,030,931 - 238,347,570 (+)Ensemblpanpan1.1panPan2
DIS3L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12543,754,382 - 44,099,497 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2543,754,484 - 44,095,381 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2544,247,553 - 44,594,062 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02544,010,739 - 44,357,418 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2544,010,802 - 44,353,289 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12543,937,826 - 44,283,331 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02543,781,874 - 44,128,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02543,936,863 - 44,283,235 (+)NCBIUU_Cfam_GSD_1.0
Dis3l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303185,881,165 - 186,220,945 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,719,121 - 5,008,014 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,718,773 - 5,058,512 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIS3L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15132,540,829 - 132,906,232 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115132,540,784 - 132,902,943 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215146,803,737 - 146,810,407 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DIS3L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110117,959,396 - 118,350,728 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10117,960,326 - 118,352,176 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604081,041,213 - 81,483,661 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000003334   ⟹   ENSHGLP00000003279
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248434,901,316 - 5,196,827 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000003335   ⟹   ENSHGLP00000003280
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248434,934,173 - 5,196,504 (+)Ensembl
RefSeq Acc Id: XM_004868059   ⟹   XP_004868116
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248434,900,811 - 5,196,827 (+)NCBI
RefSeq Acc Id: XM_021247079   ⟹   XP_021102738
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248434,900,810 - 5,196,827 (+)NCBI
RefSeq Acc Id: XM_021247080   ⟹   XP_021102739
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248434,900,811 - 5,196,827 (+)NCBI
RefSeq Acc Id: XM_021247081   ⟹   XP_021102740
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248434,900,810 - 5,196,827 (+)NCBI
RefSeq Acc Id: XM_021247082   ⟹   XP_021102741
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248434,934,173 - 5,196,827 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004868116 (Get FASTA)   NCBI Sequence Viewer  
  XP_021102738 (Get FASTA)   NCBI Sequence Viewer  
  XP_021102739 (Get FASTA)   NCBI Sequence Viewer  
  XP_021102740 (Get FASTA)   NCBI Sequence Viewer  
  XP_021102741 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003279
GenBank Protein JAN98897 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021102738   ⟸   XM_021247079
- Peptide Label: isoform X1
- UniProtKB: G5ASX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102740   ⟸   XM_021247081
- Peptide Label: isoform X3
- UniProtKB: G5ASX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102739   ⟸   XM_021247080
- Peptide Label: isoform X2
- UniProtKB: G5ASX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868116   ⟸   XM_004868059
- Peptide Label: isoform X4
- UniProtKB: G5ASX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102741   ⟸   XM_021247082
- Peptide Label: isoform X5
- UniProtKB: A0A0P6J5U0 (UniProtKB/TrEMBL),   G5ASX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000003279   ⟸   ENSHGLT00000003334
RefSeq Acc Id: ENSHGLP00000003280   ⟸   ENSHGLT00000003335


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002429 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003334 ENTREZGENE
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  2.40.50.690 UniProtKB/TrEMBL
  2.40.50.700 UniProtKB/TrEMBL
InterPro Dis3_CSD2 UniProtKB/TrEMBL
  DIS3L2 UniProtKB/TrEMBL
  Dis3l2_C UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  RNase_II/R UniProtKB/TrEMBL
  RNase_II/R_CS UniProtKB/TrEMBL
  Rrp44_CSD1 UniProtKB/TrEMBL
NCBI Gene Dis3l2 ENTREZGENE
PANTHER DIS3-LIKE EXONUCLEASE 2 UniProtKB/TrEMBL
  RIBONUCLEASE UniProtKB/TrEMBL
Pfam Dis3l2_C_term UniProtKB/TrEMBL
  OB_Dis3 UniProtKB/TrEMBL
  RNB UniProtKB/TrEMBL
  Rrp44_CSD1 UniProtKB/TrEMBL
PROSITE RIBONUCLEASE_II UniProtKB/TrEMBL
SMART RNB UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
UniProt A0A0P6J5U0 ENTREZGENE, UniProtKB/TrEMBL
  G5ASX6 ENTREZGENE, UniProtKB/TrEMBL