Ndc80 (NDC80 kinetochore complex component) - Rat Genome Database

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Gene: Ndc80 (NDC80 kinetochore complex component) Heterocephalus glaber
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Symbol: Ndc80
Name: NDC80 kinetochore complex component
RGD ID: 18906663
Description: ENCODES a protein that exhibits cyclin binding (ortholog); identical protein binding (ortholog); kinetochore adaptor activity (ortholog); INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); centrosome duplication (ortholog); chromosome segregation (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); hepatocellular carcinoma (ortholog); intellectual disability (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinetochore protein NDC80 homolog; Kinetochore protein NDC80-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477012,939,763 - 12,974,162 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477012,937,887 - 12,974,352 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ndc80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477012,939,763 - 12,974,162 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477012,937,887 - 12,974,352 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NDC80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38182,571,557 - 2,616,635 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl182,571,557 - 2,616,635 (+)EnsemblGRCh38hg38GRCh38
GRCh37182,571,556 - 2,616,634 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36182,561,605 - 2,606,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 34182,561,604 - 2,606,626NCBI
Celera182,446,814 - 2,491,757 (+)NCBICelera
Cytogenetic Map18p11.32NCBI
HuRef182,532,999 - 2,577,942 (+)NCBIHuRef
CHM1_1182,570,883 - 2,615,800 (+)NCBICHM1_1
T2T-CHM13v2.0182,727,304 - 2,772,223 (+)NCBIT2T-CHM13v2.0
Ndc80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,803,095 - 71,833,852 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,803,095 - 71,833,852 (-)EnsemblGRCm39 Ensembl
GRCm381771,496,100 - 71,526,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1771,496,100 - 71,526,857 (-)EnsemblGRCm38mm10GRCm38
MGSCv371771,845,440 - 71,876,197 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361771,400,962 - 71,431,714 (-)NCBIMGSCv36mm8
Celera1775,767,449 - 75,800,160 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
Ndc80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,853,806 - 118,887,582 (-)NCBIGRCr8
mRatBN7.29111,407,191 - 111,440,921 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9111,407,191 - 111,440,924 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9119,805,258 - 119,842,593 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09124,934,621 - 124,971,844 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09123,271,148 - 123,308,405 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09119,837,857 - 119,871,435 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,839,016 - 119,871,382 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09119,291,271 - 119,324,839 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49110,702,935 - 110,718,894 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19110,912,517 - 110,945,708 (-)NCBI
Celera9108,536,354 - 108,552,152 (-)NCBICelera
Cytogenetic Map9q38NCBI
Ndc80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554027,691,937 - 7,729,690 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554027,692,009 - 7,728,876 (-)NCBIChiLan1.0ChiLan1.0
NDC80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21735,829,184 - 35,874,768 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11821,521,776 - 21,567,360 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01811,666,099 - 11,711,456 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11813,972,637 - 14,018,261 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1813,972,637 - 14,018,261 (-)Ensemblpanpan1.1panPan2
NDC80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1769,268,218 - 69,317,126 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl769,268,242 - 69,317,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha768,723,201 - 68,772,189 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0769,329,940 - 69,378,870 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl769,329,990 - 69,378,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1769,012,589 - 69,061,471 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0769,032,710 - 69,081,627 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0769,329,927 - 69,378,829 (+)NCBIUU_Cfam_GSD_1.0
Ndc80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494465,630,900 - 65,669,747 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366721,872,193 - 1,909,675 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366721,872,205 - 1,910,956 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDC80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6103,999,034 - 104,055,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16104,000,794 - 104,055,785 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2697,024,076 - 97,061,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDC80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11861,835,027 - 61,882,660 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1861,835,064 - 61,881,627 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605036,694,925 - 36,740,902 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000009079   ⟹   ENSHGLP00000008984
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477012,939,763 - 12,974,162 (+)Ensembl
RefSeq Acc Id: XM_004853185   ⟹   XP_004853242
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477012,937,887 - 12,974,352 (+)NCBI
RefSeq Acc Id: XM_021265191   ⟹   XP_021120850
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477012,938,259 - 12,974,352 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004853242 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120850 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB18687 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008984
GenBank Protein JAN97977 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004853242   ⟸   XM_004853185
- UniProtKB: G5CAX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120850   ⟸   XM_021265191
- UniProtKB: G5CAX6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000008984   ⟸   ENSHGLT00000009079


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006458 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000009079 ENTREZGENE
Gene3D-CATH 1.10.418.30 UniProtKB/TrEMBL
  6.10.250.1950 UniProtKB/TrEMBL
InterPro DUF5595 UniProtKB/TrEMBL
  Kinetochore_Ndc80 UniProtKB/TrEMBL
  Ndc80_CH UniProtKB/TrEMBL
  Ndc80_sf UniProtKB/TrEMBL
KEGG Report hgl:101724914 UniProtKB/TrEMBL
NCBI Gene Ndc80 ENTREZGENE
PANTHER KINETOCHORE PROTEIN NDC80 HOMOLOG UniProtKB/TrEMBL
  PTHR10643 UniProtKB/TrEMBL
Pfam DUF5595 UniProtKB/TrEMBL
  Ndc80_HEC UniProtKB/TrEMBL
UniProt G5CAX6 ENTREZGENE, UniProtKB/TrEMBL