Cenpe (centromere protein E) - Rat Genome Database

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Gene: Cenpe (centromere protein E) Heterocephalus glaber
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Symbol: Cenpe
Name: centromere protein E
RGD ID: 18912455
Description: ENCODES a protein that exhibits kinetochore binding (ortholog); protein kinase binding (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); attachment of spindle microtubules to kinetochore (ortholog); chromosome segregation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); beta-mannosidosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN chromosome (ortholog); chromosome, centromeric region (ortholog); condensed chromosome, centromeric region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Centromere-associated protein E
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248304,930,555 - 4,986,076 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cenpe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248304,930,555 - 4,986,076 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CENPE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384103,105,811 - 103,198,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4103,105,349 - 103,198,445 (-)EnsemblGRCh38hg38GRCh38
GRCh374104,026,968 - 104,119,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364104,246,412 - 104,339,015 (-)NCBINCBI36Build 36hg18NCBI36
Build 344104,384,807 - 104,477,170NCBI
Celera4101,324,102 - 101,416,733 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef499,760,728 - 99,853,482 (-)NCBIHuRef
CHM1_14104,003,436 - 104,096,014 (-)NCBICHM1_1
T2T-CHM13v2.04106,417,702 - 106,510,204 (-)NCBIT2T-CHM13v2.0
Cenpe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393134,918,324 - 134,979,301 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3134,918,298 - 134,979,372 (+)EnsemblGRCm39 Ensembl
GRCm383135,212,563 - 135,273,540 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3135,212,537 - 135,273,611 (+)EnsemblGRCm38mm10GRCm38
MGSCv373134,875,527 - 134,936,504 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363135,150,046 - 135,210,626 (+)NCBIMGSCv36mm8
Celera3141,624,886 - 141,686,752 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map362.55NCBI
Cenpe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82226,310,970 - 226,369,636 (+)NCBIGRCr8
mRatBN7.22223,637,035 - 223,695,692 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2223,636,998 - 223,695,669 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02240,395,974 - 240,454,785 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2240,396,152 - 240,454,747 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02258,915,861 - 258,974,288 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42232,699,627 - 232,758,329 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12232,710,935 - 232,745,069 (+)NCBI
Celera2215,851,430 - 215,910,100 (+)NCBICelera
Cytogenetic Map2q43NCBI
Cenpe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554965,469,239 - 5,513,574 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554965,468,759 - 5,514,915 (+)NCBIChiLan1.0ChiLan1.0
CENPE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23101,187,856 - 101,281,873 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14101,474,269 - 101,568,287 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0495,562,005 - 95,654,397 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14106,185,283 - 106,277,229 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4106,185,283 - 106,277,229 (-)Ensemblpanpan1.1panPan2
CENPE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13224,447,373 - 24,530,407 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3224,447,358 - 24,530,382 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3217,493,941 - 17,576,730 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03224,666,991 - 24,749,806 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3224,669,640 - 24,739,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13224,747,174 - 24,766,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03224,427,319 - 24,510,138 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03215,352,573 - 15,435,369 (+)NCBIUU_Cfam_GSD_1.0
Cenpe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530116,845,104 - 16,922,570 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936520188,628 - 265,733 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936520188,601 - 265,904 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8117,888,970 - 117,965,252 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18117,888,968 - 117,965,325 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28126,761,254 - 126,838,996 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CENPE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1751,212,266 - 51,300,153 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603729,724,191 - 29,812,118 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001311   ⟹   ENSHGLP00000001269
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248304,930,555 - 4,986,076 (+)Ensembl
RefSeq Acc Id: XM_013066079   ⟹   XP_012921533
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245416   ⟹   XP_021101075
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245417   ⟹   XP_021101076
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245418   ⟹   XP_021101077
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245419   ⟹   XP_021101078
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245420   ⟹   XP_021101079
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245421   ⟹   XP_021101080
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245422   ⟹   XP_021101081
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,930,533 - 4,986,437 (+)NCBI
RefSeq Acc Id: XM_021245423   ⟹   XP_021101082
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248304,933,801 - 4,986,437 (+)NCBI
RefSeq Acc Id: XP_012921533   ⟸   XM_013066079
- Peptide Label: isoform X1
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6QMI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101081   ⟸   XM_021245422
- Peptide Label: isoform X8
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RUX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101079   ⟸   XM_021245420
- Peptide Label: isoform X6
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RX82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101076   ⟸   XM_021245417
- Peptide Label: isoform X3
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RX38 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101075   ⟸   XM_021245416
- Peptide Label: isoform X2
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RY94 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101080   ⟸   XM_021245421
- Peptide Label: isoform X7
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6S0C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101077   ⟸   XM_021245418
- Peptide Label: isoform X4
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RZB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101078   ⟸   XM_021245419
- Peptide Label: isoform X5
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RXQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101082   ⟸   XM_021245423
- Peptide Label: isoform X9
- UniProtKB: G5BXB1 (UniProtKB/TrEMBL),   A0AAX6RTD6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001269   ⟸   ENSHGLT00000001311


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000989 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001311 ENTREZGENE
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
  Kinesin motor domain UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_reg_dom UniProtKB/TrEMBL
NCBI Gene Cenpe ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/TrEMBL
  CENTROMERE-ASSOCIATED PROTEIN E UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/TrEMBL
  PARP_ALPHA_HD UniProtKB/TrEMBL
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt A0AAX6QMI6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RTD6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RUX7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RX38 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RX82 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RXQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RY94 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RZB2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S0C7 ENTREZGENE, UniProtKB/TrEMBL
  G5BXB1 ENTREZGENE, UniProtKB/TrEMBL