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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of circadian rhythm
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Accession:GO:0042754 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
Synonyms:exact_synonym: down regulation of circadian rhythm;   downregulation of circadian rhythm
 narrow_synonym: inhibition of circadian rhythm



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negative regulation of circadian rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cipc CLOCK-interacting pacemaker involved_in ISO (PMID:17310242) RGD PMID:17310242 NCBI chr 6:106,595,011...106,613,732 JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:17310242), (PMID:19605937)
UniProt
RGD
PMID:17310242 PMID:19605937 GO_REF:0000024 NCBI chr 7:18,529,823...18,594,092 JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19605937)
UniProt
Ensembl
RGD
PMID:19605937 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:78,374,995...78,405,001 JBrowse link
G Pasd1 PAS domain containing repressor 1 involved_in ISO
IBA
(PMID:25936801)
GO_REF:0000033
RGD
GO_Central
PMID:25936801 GO_REF:0000033 NCBI chr  X:149,617,933...149,639,214 JBrowse link
G Per2 period circadian regulator 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19605937)
UniProt
RGD
PMID:19605937 GO_REF:0000024 NCBI chr 9:92,007,289...92,049,551 JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 involved_in ISO (PMID:28903391) RGD PMID:28903391 NCBI chr15:45,431,402...45,498,034 JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:21680841) RGD PMID:21680841 NCBI chr 5:139,338,034...139,353,476 JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:21680841) RGD PMID:21680841 NCBI chr 8:57,481,539...57,536,195 JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:152,398,745...152,422,854 JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:45,658,872...45,695,821 JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:148,421,315...148,431,128 JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:45,658,872...45,695,821 JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:10,545,488...10,550,029 JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:58,605,403...58,669,339 JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:246,606,131...246,750,970 JBrowse link
negative regulation of locomotor rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:16982424 RGD:10412019 NCBI chr 5:116,294,409...116,477,904 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    negative regulation of biological process 5816
      negative regulation of circadian rhythm 15
        negative regulation of circadian sleep/wake cycle, sleep + 5
        negative regulation of circadian sleep/wake cycle, wakefulness 1
        negative regulation of locomotor rhythm 1
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of circadian rhythm 130
          negative regulation of circadian rhythm 15
            negative regulation of circadian sleep/wake cycle, sleep + 5
            negative regulation of circadian sleep/wake cycle, wakefulness 1
            negative regulation of locomotor rhythm 1
paths to the root