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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol transport
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Accession:GO:0032374 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.



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regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382
JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21147780) Ensembl
MGI
PMID:21147780 GO_REF:0000107 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (PMID:19718435) BHF-UCL PMID:19718435 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G OSBPL6 oxysterol binding protein like 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:65,449,726...65,656,040
Ensembl chr2B:183,247,028...183,361,686
JBrowse link
G SEC24A SEC24 homolog A, COPII coat complex component acts_upstream_of_or_within ISO (PMID:23580231) MGI PMID:23580231 NCBI chr 5:130,050,625...130,128,212
Ensembl chr 5:136,197,746...136,273,158
JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484) ARUK-UCL
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (PMID:19752193) UniProt PMID:19752193 NCBI chr  X:143,560,802...143,570,185
Ensembl chr  X:153,446,827...153,460,602
JBrowse link
G LOC100990946 group 10 secretory phospholipase A2 involved_in ISO (PMID:20844270) BHF-UCL PMID:20844270 NCBI chr16:13,600,152...13,622,629 JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:15358760) BHF-UCL
Ensembl
PMID:15358760 GO_REF:0000107 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in ISO (PMID:10764676) BHF-UCL PMID:10764676 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959
JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460
JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in ISO (PMID:8636092) BHF-UCL PMID:8636092 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959
JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:10978346) BHF-UCL PMID:10978346
G APOC2 apolipoprotein C2 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr19:41,892,954...41,896,461 JBrowse link
G LOC100994952 apolipoprotein C-I, acidic form involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:41,862,168...41,878,231 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484) ARUK-UCL
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484) ARUK-UCL
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456
JBrowse link
positive regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188
JBrowse link
G ABCA12 ATP binding cassette subfamily A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23931754) Ensembl
MGI
PMID:23931754 GO_REF:0000107 NCBI chr2B:102,194,286...102,401,175
Ensembl chr2B:220,668,957...220,873,566
JBrowse link
G ABCA3 ATP binding cassette subfamily A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,132,435...1,196,226
Ensembl chr16:2,376,006...2,437,427
JBrowse link
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:18429932) Alzheimers_University_of_Toronto PMID:18429932 NCBI chr19:62,811...77,897
Ensembl chr19:1,018,095...1,042,104
JBrowse link
G ABCA8 ATP binding cassette subfamily A member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:62,803,735...62,892,397
Ensembl chr17:68,192,993...68,281,666
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15210959) BHF-UCL PMID:15210959 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050
JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,987,709...114,001,354
Ensembl chr11:117,916,043...117,929,636
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G APOA1 apolipoprotein A1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:36,780,705...36,923,248
Ensembl chr 7:37,012,129...37,153,307
JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,346,766...7,349,682
Ensembl chr17:7,333,571...7,335,871
JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (PMID:19718435) BHF-UCL PMID:19718435 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in ISO (PMID:16938301) BHF-UCL PMID:16938301 NCBI chr14:16,155,331...16,158,588 JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23931754) Ensembl
MGI
PMID:23931754 GO_REF:0000107 NCBI chr19:47,340,077...47,346,737
Ensembl chr19:56,243,124...56,250,024
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,195,122...47,215,277
Ensembl chr11:47,748,353...47,768,672
JBrowse link
G PLTP phospholipid transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,237,434...42,251,189
Ensembl chr20:43,324,609...43,337,999
JBrowse link
G PON1 paraoxonase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of
involved_in
ISO (PMID:24751522)
(PMID:16530456)
BHF-UCL
AgBase
PMID:16530456 PMID:24751522 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PTCH1 patched 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
JBrowse link
G ZDHHC8 zinc finger DHHC-type palmitoyltransferase 8 involved_in ISO (PMID:19556522) UniProt PMID:19556522 NCBI chr22:2,891,738...2,894,404 JBrowse link
positive regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMMD1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO (PMID:26965651) MGI PMID:26965651 NCBI chr2A:61,970,830...62,216,677
Ensembl chr2A:63,121,521...63,349,131
JBrowse link
G LRP1 LDL receptor related protein 1 ISO RGD PMID:22454363 RGD:13800524 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979
JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:16772292 RGD:9850270 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939
JBrowse link
positive regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA13 ATP binding cassette subfamily A member 13 involved_in ISO (PMID:33478937) UniProt PMID:33478937 NCBI chr 7:48,812,624...49,288,605
Ensembl chr 7:48,920,381...49,393,235
JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,395,924...79,469,755
Ensembl chr 7:93,046,085...93,119,439
JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103
JBrowse link
G LIPG lipase G, endothelial type involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,942,132...42,972,112
Ensembl chr18:46,292,154...46,320,652
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:47,340,077...47,346,737
Ensembl chr19:56,243,124...56,250,024
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,195,122...47,215,277
Ensembl chr11:47,748,353...47,768,672
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of ISO (PMID:17611579) BHF-UCL PMID:17611579 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:16530456) AgBase PMID:16530456 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G SCP2 sterol carrier protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250
JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:24,809,535...24,852,394
Ensembl chr 1:25,878,358...25,903,336
JBrowse link
G LOC100974752 annexin A2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:33,428,190...33,429,273
Ensembl chr15:57,625,425...57,674,250
JBrowse link
positive regulation of reverse cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:63,172,670...63,255,587
Ensembl chr17:68,563,702...68,629,791
JBrowse link
regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA5 ATP binding cassette subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:63,172,670...63,255,587
Ensembl chr17:68,563,702...68,629,791
JBrowse link
G ABCA8 ATP binding cassette subfamily A member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:62,803,735...62,892,397
Ensembl chr17:68,192,993...68,281,666
JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link
G NAXE NAD(P)HX epimerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,935,295...131,937,843
Ensembl chr 1:135,758,868...135,761,416
JBrowse link
G TTC39B tetratricopeptide repeat domain 39B involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr 9:14,994,729...15,127,877
Ensembl chr 9:15,502,811...15,633,374
JBrowse link
regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776
JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:206,527,777...206,549,606
Ensembl chr 1:211,554,553...211,576,484
JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within ISO (PMID:19723497) MGI PMID:19723497 NCBI chr 6:115,486,422...115,521,317 JBrowse link
G TMEM97 transmembrane protein 97 involved_in ISO (PMID:27378690) UniProt PMID:27378690 NCBI chr17:28,446,213...28,455,332 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    localization 5258
      regulation of localization 2274
        regulation of lipid localization 180
          regulation of lipid transport 148
            regulation of sterol transport 56
              regulation of cholesterol transport 56
                negative regulation of cholesterol transport + 13
                positive regulation of cholesterol transport + 34
                regulation of cholesterol efflux + 35
                regulation of cholesterol import + 6
                regulation of intracellular cholesterol transport + 10
                regulation of reverse cholesterol transport + 1
Path 2
Term Annotations click to browse term
  biological_process 16644
    localization 5258
      establishment of localization 4571
        transport 4272
          lipid transport 408
            sterol transport 109
              cholesterol transport 104
                regulation of cholesterol transport 56
                  negative regulation of cholesterol transport + 13
                  positive regulation of cholesterol transport + 34
                  regulation of cholesterol efflux + 35
                  regulation of cholesterol import + 6
                  regulation of intracellular cholesterol transport + 10
                  regulation of reverse cholesterol transport + 1
paths to the root