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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol transport
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Accession:GO:0032375 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of cholesterol transport;   downregulation of cholesterol transport
 narrow_synonym: inhibition of cholesterol transport


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negative regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:8636092) RGD PMID:8636092 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc1 apolipoprotein C1 involved_in IBA
ISO
PMID:21873635
(PMID:10978346)
RGD PMID:10978346 PMID:21873635 RGD:13792537 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:15778093) RGD PMID:15778093 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G LOC100910181 apolipoprotein C-I-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:12042316) RGD PMID:12042316 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Egf epidermal growth factor involved_in ISO (MGI:4460848|PMID:20037141) RGD PMID:20037141 MGI:4460848 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) RGD PMID:19752193 MGI:4411947 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
GO_REF:0000107
(MGI:5051938|PMID:20844270)
Ensembl
RGD
PMID:20844270 GO_REF:0000107 MGI:5051938 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
GO_REF:0000107
(MGI:5306540|PMID:21931618)
Ensembl
RGD
PMID:21931618 GO_REF:0000107 MGI:5306540 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:15358760)
Ensembl
RGD
PMID:15358760 GO_REF:0000107 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:10764676) RGD PMID:10764676 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:15778093)
GO_REF:0000107
RGD
Ensembl
PMID:15778093 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5613
      negative regulation of transport 529
        negative regulation of lipid transport 36
          negative regulation of sterol transport 15
            negative regulation of cholesterol transport 15
              negative regulation of cholesterol efflux 7
              negative regulation of cholesterol import 2
              negative regulation of intestinal cholesterol absorption 2
              negative regulation of intracellular cholesterol transport + 2
              negative regulation of reverse cholesterol transport 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      establishment of localization 4864
        transport 4700
          organic substance transport 2479
            lipid transport 406
              sterol transport 119
                regulation of sterol transport 65
                  negative regulation of sterol transport 15
                    negative regulation of cholesterol transport 15
                      negative regulation of cholesterol efflux 7
                      negative regulation of cholesterol import 2
                      negative regulation of intestinal cholesterol absorption 2
                      negative regulation of intracellular cholesterol transport + 2
                      negative regulation of reverse cholesterol transport 0
paths to the root