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ONTOLOGY REPORT - ANNOTATIONS

Term:nonribosomal peptide biosynthetic process
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Accession:GO:0019184 term browser browse the term
Definition:The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
Synonyms:exact_synonym: non-ribosomal peptide biosynthesis;   non-ribosomal peptide biosynthetic process;   non-ribosomal peptide formation;   non-ribosomal peptide synthesis;   nonribosomal peptide anabolism;   nonribosomal peptide biosynthesis;   nonribosomal peptide formation;   nonribosomal peptide synthesis
 related_synonym: nonribosomal peptide synthetase


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amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdh aminoadipate-semialdehyde dehydrogenase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:24467666)		 GO_Central
RGD		 PMID:24467666 GO_REF:0000033 NCBI chr14:31,255,019...31,281,802
Ensembl chr14:31,255,310...31,281,796 		JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
ISS		 MGI:2387010 (PMID:10805773), (PMID:16081425)
GO_REF:0000033
GO_REF:0000041
(PMID:10395918), (PMID:12663448), (PMID:8104187), (PMID:9675072)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:8104187 PMID:9675072 PMID:10395918 PMID:10805773 PMID:12663448 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000041, RGD:1582661 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
ISS		 (PMID:16081425)
GO_REF:0000033
GO_REF:0000041
(PMID:10395918), (PMID:12081989), (PMID:9675072)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:9675072 PMID:10395918 PMID:12081989 PMID:16081425 PMID:16183645 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041, RGD:1582661 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12468440)		 Ensembl
RGD		 PMID:12468440 GO_REF:0000107 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ggt5 gamma-glutamyltransferase 5 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450 		JBrowse link
G Ggt6 gamma-glutamyl transferase 6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:57,051,977...57,054,900
Ensembl chr10:57,051,825...57,067,260 		JBrowse link
G Ggt7 gamma-glutamyltransferase 7 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:143,978,073...144,004,597
Ensembl chr 3:143,978,082...144,001,492 		JBrowse link
G Gss glutathione synthetase involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:10964706 GO_REF:0000041, RGD:1599340 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Hagh hydroxyacyl glutathione hydrolase involved_in IEA
ISO		 GO_REF:0000107
(PMID:8550579)		 Ensembl
RGD		 PMID:8550579 GO_REF:0000107 NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:8703034) RGD PMID:8703034 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:12614333) RGD PMID:12614333 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12614333)		 Ensembl
RGD		 PMID:12614333 GO_REF:0000107 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (PMID:14978030) RGD PMID:14978030 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:14978030) RGD PMID:14978030 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (PMID:16037214) RGD PMID:16037214 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdh2 3-hydroxybutyrate dehydrogenase 2 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:20550936)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:20550936 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        biosynthetic process 8469
          peptide biosynthetic process 25
            nonribosomal peptide biosynthetic process 16
              amino acid activation for nonribosomal peptide biosynthetic process + 1
              glutathione biosynthetic process + 14
              siderophore biosynthetic process + 1
              vancomycin biosynthetic process 0
paths to the root