Hagh (hydroxyacyl glutathione hydrolase)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Hagh (hydroxyacyl glutathione hydrolase) Rattus norvegicus

Analyze

Symbol:

Hagh

Name:

hydroxyacyl glutathione hydrolase

RGD ID:

2779

Description:

Enables hydroxyacylglutathione hydrolase activity. Involved in glutathione metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human HAGH (hydroxyacylglutathione hydrolase); PARTICIPATES IN glyoxalase metabolic pathway; Leigh disease pathway; primary hyperoxaluria type 2 pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Glo2; glx II; glyoxalase II; hydroxyacylglutathione hydrolase; hydroxyacylglutathione hydrolase, mitochondrial; round spermatid protein RSP29; RSP29

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HAGH (hydroxyacylglutathione hydrolase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Hagh (hydroxyacyl glutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hagh (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HAGH (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HAGH (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hagh (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HAGH (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HAGH (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hagh (hydroxyacylglutathione hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HAGHL (hydroxyacylglutathione hydrolase like)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	HAGH (hydroxyacylglutathione hydrolase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hagh (hydroxyacyl glutathione hydrolase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hagh (hydroxyacylglutathione hydrolase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GLO2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y17G7B.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	tzn	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GLO4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hagh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	13,874,883 - 13,889,527 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	13,875,241 - 13,889,504 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	18,622,292 - 18,636,594 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	18,111,152 - 18,125,454 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	13,610,369 - 13,624,671 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	14,215,913 - 14,230,506 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,216,155 - 14,230,515 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	14,106,047 - 14,117,459 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	14,106,046 - 14,117,459 (+)	NCBI
Celera	10	13,554,443 - 13,568,735 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

epilepsy (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Glyoxalase II Deficiency (ISO)

idiopathic generalized epilepsy (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

tuberous sclerosis 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

4,4'-diaminodiphenylmethane (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

carmustine (ISO)

chrysene (ISO)

cisplatin (ISO)

clofibrate (EXP)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (EXP,ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

elemental selenium (ISO)

ethanol (ISO)

fenvalerate (EXP)

fumonisin B1 (ISO)

gentamycin (EXP)

Heptachlor epoxide (ISO)

ivermectin (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nitrofen (EXP)

O-methyleugenol (ISO)

ochratoxin A (EXP)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

pirinixic acid (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thapsigargin (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutathione biosynthetic process (IEA,ISO)

glutathione metabolic process (IBA,IDA)

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (IEA)

spermatogenesis (NAS)

Cellular Component

cytoplasm (ISO)

mitochondrial matrix (IEA,ISO)

mitochondrion (IBA)

Molecular Function

hydroxyacylglutathione hydrolase activity (IBA,IDA,IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glyoxalase metabolic pathway (ISO)

Leigh disease pathway (ISO)

primary hyperoxaluria type 2 pathway (ISO)

pyruvate decarboxylase deficiency pathway (ISO)

pyruvate dehydrogenase E1 deficiency pathway (ISO)

pyruvate kinase deficiency of red cells pathway (ISO)

pyruvate metabolic pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	cDNA cloning and characterization of a rat spermatogenesis-associated protein RSP29.	Ji X, etal., Biochem Biophys Res Commun 1997 Dec 29;241(3):714-9.
4.	Contents of D-lactate and its related metabolites as well as enzyme activities in the liver, muscle and blood plasma of aging rats.	Kawase M, etal., Mech Ageing Dev. 1995 Sep 29;84(1):55-63.
5.	Changes in concentrations of methylglyoxal, D-lactate and glyoxalase activities in liver and plasma of rats fed a 3'-methyl-4-dimethylaminoazobenzene-rich diet.	Kawase M, etal., Res Exp Med (Berl). 1996;196(4):251-9.
6.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
11.	GOA pipeline	RGD automated data pipeline
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1914521	PMID:8550579	PMID:12477932	PMID:15117945	PMID:18614015	PMID:22171037	PMID:22893478	PMID:23376485

Genomics

Comparative Map Data

Hagh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	13,874,883 - 13,889,527 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	13,875,241 - 13,889,504 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	18,622,292 - 18,636,594 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	18,111,152 - 18,125,454 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	13,610,369 - 13,624,671 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	14,215,913 - 14,230,506 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,216,155 - 14,230,515 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	14,106,047 - 14,117,459 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	14,106,046 - 14,117,459 (+)	NCBI
Celera	10	13,554,443 - 13,568,735 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

HAGH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	1,807,629 - 1,827,194 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	1,795,620 - 1,827,157 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	1,857,630 - 1,877,195 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	1,799,105 - 1,817,196 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	1,799,105 - 1,817,163	NCBI
Celera	16	2,071,349 - 2,089,441 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	1,781,967 - 1,800,219 (-)	NCBI		HuRef
CHM1_1	16	1,859,060 - 1,877,163 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	1,823,468 - 1,843,048 (-)	NCBI		T2T-CHM13v2.0

Hagh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	25,056,863 - 25,083,424 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	25,059,117 - 25,083,424 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	24,839,781 - 24,864,450 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	24,840,143 - 24,864,450 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	24,987,435 - 25,001,395 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	24,578,147 - 24,592,050 (+)	NCBI		MGSCv36	mm8
Celera	17	25,377,454 - 25,391,223 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.53	NCBI

Hagh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,451,910 - 15,465,211 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	15,451,910 - 15,465,211 (+)	NCBI	ChiLan1.0	ChiLan1.0

HAGH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	5,857,103 - 5,880,906 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	431,417 - 455,211 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	1,864,372 - 1,865,276 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

HAGH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	39,076,364 - 39,105,646 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	39,084,513 - 39,105,592 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,323,559 - 40,344,553 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,400,917 - 39,422,090 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,375,311 - 39,422,080 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	39,077,630 - 39,098,788 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	39,050,207 - 39,071,366 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,528,902 - 39,549,839 (+)	NCBI		UU_Cfam_GSD_1.0

Hagh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,510,713 - 104,528,007 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	2,181,501 - 2,194,007 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936694	2,181,475 - 2,200,469 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HAGH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	40,139,099 - 40,162,921 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HAGH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	1,705,436 - 1,730,896 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	1,713,542 - 1,730,797 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	29,352,945 - 29,370,176 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hagh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	434,537 - 446,061 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624913	426,554 - 446,061 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Hagh
21 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	83
Interacting mature miRNAs:	85
Transcripts:	ENSRNOT00000020192
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	1	24158324	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35225947	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38328221	Rat
7411611	Foco17	Food consumption QTL 17	18.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	1	42315980	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	418344	45418344	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
1576304	Schws7	Schwannoma susceptibility QTL 7		0.0115	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	4765527	19816042	Rat
631828	Alc5	Alcohol consumption QTL 5	2.4		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	5144027	17245662	Rat
737820	Alc9	Alcohol consumption QTL 9	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	5144027	19233348	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5387014	50387014	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5387014	50387014	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5387014	50387014	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6154182	15990232	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6375746	51375746	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat

Markers in Region

RH133587

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	13,873,671 - 13,873,891 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,214,651 - 14,214,870	NCBI	Rnor6.0
Rnor_5.0	10	14,030,666 - 14,030,885	UniSTS	Rnor5.0
RGSC_v3.4	10	14,101,757 - 14,101,976	UniSTS	RGSC3.4
Celera	10	13,552,881 - 13,553,100	UniSTS
Cytogenetic Map	10	q12	UniSTS

D10Bda1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	13,888,800 - 13,889,419 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,229,780 - 14,230,398	NCBI	Rnor6.0
Rnor_5.0	10	14,045,795 - 14,046,413	UniSTS	Rnor5.0
RGSC_v3.4	10	14,116,886 - 14,117,504	UniSTS	RGSC3.4
Celera	10	13,568,009 - 13,568,627	UniSTS
Cytogenetic Map	10	q12	UniSTS

RH141944

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	10	q12	UniSTS

MARC_5473-5474:996690420:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	13,878,016 - 13,878,777 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,218,996 - 14,219,756	NCBI	Rnor6.0
Rnor_5.0	10	14,035,011 - 14,035,771	UniSTS	Rnor5.0
RGSC_v3.4	10	14,106,102 - 14,106,862	UniSTS	RGSC3.4
Celera	10	13,557,225 - 13,557,985	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	72	35	41	11	8
Low									2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_033349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC130925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB715597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U97667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000020192 ⟹ ENSRNOP00000020192

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	13,875,241 - 13,889,504 (+)	Ensembl
Rnor_6.0 Ensembl	10	14,216,155 - 14,230,515 (+)	Ensembl

RefSeq Acc Id:

NM_033349 ⟹ NP_203500

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	13,875,234 - 13,889,527 (+)	NCBI
Rnor_6.0	10	14,216,213 - 14,230,506 (+)	NCBI
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI
RGSC_v3.4	10	14,106,047 - 14,117,459 (+)	RGD
Celera	10	13,554,443 - 13,568,735 (+)	NCBI

Sequence:

show sequence

GGACTCCGCGACCCGGCTGTGCACCCCGTGGGTCATGGTGCTGGGTCGCGGGTCGCTGTGCCTC
CGGAGCCTGTCAGTGCTGGGAGCCGCCTGCGCGCGCCGCGGTCTGGGTCAGGCTCTGCTGGGAC
TCTCTCTCTGTCACACAGACTTCAGGAAGAATCTGACCGTGCAGCAAGACATGATGAAGATCGA
ACTACTGCCTGCCCTGACTGACAACTACATGTACCTGATCATTGATGAGGACACCCAGGAGGCC
GCCGTTGTGGACCCAGTGCAGCCACAGAAGGTTATAGAAACTGTGAAAAAGCACCGTGTGAAGC
TGACCACAGTGCTCACCACTCACCACCACTGGGACCACGCTGGTGGGAACGAGAAGTTGGTGAA
GCTGGAACCTGGGCTGAAGGTTTATGGAGGTGATGACCGCATTGGGGCCTTGACCCACAAGGTC
ACACACCTTTCCACACTGCAGGTGGGGTCTCTCAGTGTCAAATGTCTGTCAACACCCTGCCATA
CTTCAGGGCACATCTGTTACTTTGTGAGCAAGCCTGGTAGCTCAGAGCCTTCTGCTGTGTTCAC
AGGTGACACATTGTTTGTTGCTGGCTGTGGGAAGTTCTATGAGGGAACCGCAGACGAGATGTAC
AAGGCGCTGCTTGAAGTCTTAGGCCGGCTTCCTCCAGACACAAAAGTCTACTGTGGCCATGAAT
ACACCGTAAACAACCTTAAGTTTGCGCGCCATGTGGAGCCCGGCAATACCGCCGTTCAAGAGAA
ACTGGCCTGGGCCAAGGAGAAGAATGCCATCGGGGAGCCCACGGTGCCATCCACCCTGGCAGAG
GAGTTCACTTACAACCCCTTCATGAGAGTGAAGGAGAAGACCGTGCAGCAGCACGCTGGAGAGA
CCGACCCTGTGACCACCATGAGGGCCATCCGCAGGGAGAAAGACCAGTTTAAGGTGCCTCGGGA
CTGAGGAACACGGGGACAGGGACTTTTAACTGACTGTCCTGCTGCTAAAGCAGGACCTAGTCTA
ATTTTAAGTTAATTCAAAGCCCTTAGCTTGTGTTGTCAAATGTTCTAATGCATATTTATAAGAG
AAAAAGGTTTAAAGTATTTATTCCCATAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006245899 ⟹ XP_006245961

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	13,875,295 - 13,889,527 (+)	NCBI
Rnor_6.0	10	14,216,322 - 14,230,506 (+)	NCBI
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI

Sequence:

show sequence

GGTAAGTGTGTCTAGGCACTGACGCGGCGCGGCCGGGTGCCGGAGGCCGGACGTCGGTTGGGCG
AGCCCTCGCTGTCTTCAGGCGCAGGTCAGGCTCTGCTGGGACTCTCTCTCTGTCACACAGACTT
CAGGAAGAATCTGACCGTGCAGCAAGACATGATGAAGATCGAACTACTGCCTGCCCTGACTGAC
AACTACATGTACCTGATCATTGATGAGGACACCCAGGAGGCCGCCGTTGTGGACCCAGTGCAGC
CACAGAAGGTTATAGAAACTGTGAAAAAGCACCGTGTGAAGCTGACCACAGTGCTCACCACTCA
CCACCACTGGGACCACGCTGGTGGGAACGAGAAGTTGGTGAAGCTGGAACCTGGGCTGAAGGTT
TATGGAGGTGATGACCGCATTGGGGCCTTGACCCACAAGGTCACACACCTTTCCACACTGCAGG
TGGGGTCTCTCAGTGTCAAATGTCTGTCAACACCCTGCCATACTTCAGGGCACATCTGTTACTT
TGTGAGCAAGCCTGGTAGCTCAGAGCCTTCTGCTGTGTTCACAGGTGACACATTGTTTGTTGCT
GGCTGTGGGAAGTTCTATGAGGGAACCGCAGACGAGATGTACAAGGCGCTGCTTGAAGTCTTAG
GCCGGCTTCCTCCAGACACAAAAGTCTACTGTGGCCATGAATACACCGTAAACAACCTTAAGTT
TGCGCGCCATGTGGAGCCCGGCAATACCGCCGTTCAAGAGAAACTGGCCTGGGCCAAGGAGAAG
AATGCCATCGGGGAGCCCACGGTGCCATCCACCCTGGCAGAGGAGTTCACTTACAACCCCTTCA
TGAGAGTGAAGGAGAAGACCGTGCAGCAGCACGCTGGAGAGACCGACCCTGTGACCACCATGAG
GGCCATCCGCAGGGAGAAAGACCAGTTTAAGGTGCCTCGGGACTGAGGAACACGGGGACAGGGA
CTTTTAACTGACTGTCCTGCTGCTAAAGCAGGACCTAGTCTAATTTTAAGTTAATTCAAAGCCC
TTAGCTTGTGTTGTCAAATGTTCTAATGCATATTTATAAGAGAAAAAGGTTTAAAGTATTTATT
CCCATAA

hide sequence

RefSeq Acc Id:

XM_006245900 ⟹ XP_006245962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	13,874,883 - 13,889,527 (+)	NCBI
Rnor_6.0	10	14,215,913 - 14,230,506 (+)	NCBI
Rnor_5.0	10	14,032,006 - 14,046,521 (+)	NCBI

Sequence:

show sequence

AGGAGGCGCACGCTTAGCCTCCCACCTCCTTCTCCACCTACTTCCAGACCCGGTCTCCCAGCCA
AGGCTTCCAGGGCAGGTCAGGCTCTGCTGGGACTCTCTCTCTGTCACACAGACTTCAGGAAGAA
TCTGACCGTGCAGCAAGACATGATGAAGATCGAACTACTGCCTGCCCTGACTGACAACTACATG
TACCTGATCATTGATGAGGACACCCAGGAGGCCGCCGTTGTGGACCCAGTGCAGCCACAGAAGG
TTATAGAAACTGTGAAAAAGCACCGTGTGAAGCTGACCACAGTGCTCACCACTCACCACCACTG
GGACCACGCTGGTGGGAACGAGAAGTTGGTGAAGCTGGAACCTGGGCTGAAGGTTTATGGAGGT
GATGACCGCATTGGGGCCTTGACCCACAAGGTCACACACCTTTCCACACTGCAGGTGGGGTCTC
TCAGTGTCAAATGTCTGTCAACACCCTGCCATACTTCAGGGCACATCTGTTACTTTGTGAGCAA
GCCTGGTAGCTCAGAGCCTTCTGCTGTGTTCACAGGTGACACATTGTTTGTTGCTGGCTGTGGG
AAGTTCTATGAGGGAACCGCAGACGAGATGTACAAGGCGCTGCTTGAAGTCTTAGGCCGGCTTC
CTCCAGACACAAAAGTCTACTGTGGCCATGAATACACCGTAAACAACCTTAAGTTTGCGCGCCA
TGTGGAGCCCGGCAATACCGCCGTTCAAGAGAAACTGGCCTGGGCCAAGGAGAAGAATGCCATC
GGGGAGCCCACGGTGCCATCCACCCTGGCAGAGGAGTTCACTTACAACCCCTTCATGAGAGTGA
AGGAGAAGACCGTGCAGCAGCACGCTGGAGAGACCGACCCTGTGACCACCATGAGGGCCATCCG
CAGGGAGAAAGACCAGTTTAAGGTGCCTCGGGACTGAGGAACACGGGGACAGGGACTTTTAACT
GACTGTCCTGCTGCTAAAGCAGGACCTAGTCTAATTTTAAGTTAATTCAAAGCCCTTAGCTTGT
GTTGTCAAATGTTCTAATGCATATTTATAAGAGAAAAAGGTTTAAAGTATTTATTCCCATAA

hide sequence

RefSeq Acc Id:

XM_039085186 ⟹ XP_038941114

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	13,875,690 - 13,889,527 (+)	NCBI

RefSeq Acc Id:

XM_039085187 ⟹ XP_038941115

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	13,875,185 - 13,889,527 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_203500	(Get FASTA)	NCBI Sequence Viewer
	XP_006245961	(Get FASTA)	NCBI Sequence Viewer
	XP_006245962	(Get FASTA)	NCBI Sequence Viewer
	XP_038941114	(Get FASTA)	NCBI Sequence Viewer
	XP_038941115	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC39944	(Get FASTA)	NCBI Sequence Viewer
	AAH97301	(Get FASTA)	NCBI Sequence Viewer
	EDM03882	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020192
	ENSRNOP00000020192.4
GenBank Protein	O35952	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_203500 ⟸ NM_033349
- Peptide Label:	precursor
- UniProtKB:	Q4V8M8 (UniProtKB/Swiss-Prot), O35952 (UniProtKB/Swiss-Prot), A6HCX7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLGRGSLCLRSLSVLGAACARRGLGQALLGLSLCHTDFRKNLTVQQDMMKIELLPALTDNYMY LIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGD DRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGDTLFVAGCGK FYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVNNLKFARHVEPGNTAVQEKLAWAKEKNAIG EPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAIRREKDQFKVPRD hide sequence

RefSeq Acc Id:	XP_006245962 ⟸ XM_006245900
- Peptide Label:	isoform X1
- UniProtKB:	Q4V8M8 (UniProtKB/Swiss-Prot), O35952 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMKIELLPALTDNYMYLIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGN EKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEP SAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVNNLKFARHVEPGNT AVQEKLAWAKEKNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAIRREKDQF KVPRD hide sequence

RefSeq Acc Id:	XP_006245961 ⟸ XM_006245899
- Peptide Label:	isoform X1
- UniProtKB:	Q4V8M8 (UniProtKB/Swiss-Prot), O35952 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMKIELLPALTDNYMYLIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGN EKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEP SAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVNNLKFARHVEPGNT AVQEKLAWAKEKNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAIRREKDQF KVPRD hide sequence

RefSeq Acc Id:

ENSRNOP00000020192 ⟸ ENSRNOT00000020192

RefSeq Acc Id:	XP_038941115 ⟸ XM_039085187
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038941114 ⟸ XM_039085186
- Peptide Label:	isoform X1
- UniProtKB:	Q4V8M8 (UniProtKB/Swiss-Prot), O35952 (UniProtKB/Swiss-Prot)

Protein Domains

Metallo-beta-lactamase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35952-F1-model_v2	AlphaFold	O35952	1-309	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697030

Promoter ID:

EPDNEW_R7555

Type:

initiation region

Name:

Hagh_1

Description:

hydroxyacyl glutathione hydrolase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	14,216,220 - 14,216,280	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2779	AgrOrtholog
BioCyc Gene	G2FUF-25820	BioCyc
Ensembl Genes	ENSRNOG00000014743	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020192	ENTREZGENE
	ENSRNOT00000020192.6	UniProtKB/TrEMBL
Gene3D-CATH	3.60.15.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7460472	IMAGE-MGC_LOAD
InterPro	Clx_II_MBL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HAGH_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Hydroxyacylglutathione_Hdrlase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Metallo-B-lactamas	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RibonucZ/Hydroxyglut_hydro	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:24439	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:114294	IMAGE-MGC_LOAD
NCBI Gene	24439	ENTREZGENE
PANTHER	BETA LACTAMASE DOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HAGH_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lactamase_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Hagh	PhenoGen
PIRSF	Glx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014743	RatGTEx
SMART	Lactamase_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56281	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6HCX7	ENTREZGENE, UniProtKB/TrEMBL
	F1LQI1_RAT	UniProtKB/TrEMBL
	GLO2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q4V8M8	ENTREZGENE
UniProt Secondary	Q4V8M8	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Hagh	Hydroxyacyl glutathione hydrolase			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_evolution	predicted protein sequence is highly conserved among eukaryotes	728643
gene_expression	mRNA is expressed in many tissues, particularly in the testis	728643

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)