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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:neuropeptide signaling pathway
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Accession:GO:0007218 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Synonyms:exact_synonym: neuropeptide signalling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi

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neuropeptide signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624770:11,359,606...11,375,833
Ensembl chrNW_004624770:11,358,286...11,375,813 		JBrowse link
G Agrp agouti related neuropeptide acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9311920) RGD
MGI
Ensembl
TreeGrafter		 PMID:9311920 PMID:10875247 GO_REF:0000107 GO_REF:0000118 RGD:632165 NCBI chrNW_004624746:18,826,206...18,827,453
Ensembl chrNW_004624746:18,826,545...18,827,299 		JBrowse link
G Brs3 bombesin receptor subtype 3 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624808:10,652,817...10,658,434
Ensembl chrNW_004624808:10,652,776...10,658,498 		JBrowse link
G Calca calcitonin related polypeptide alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7698182) MGI
Ensembl		 PMID:7698182 GO_REF:0000107 NCBI chrNW_004624766:6,764,388...6,771,396
Ensembl chrNW_004624766:6,766,185...6,768,173 		JBrowse link
G Cartpt CART prepropeptide involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624905:751,032...753,012
Ensembl chrNW_004624905:751,223...752,845 		JBrowse link
G Cckar cholecystokinin A receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624755:6,122,181...6,132,623
Ensembl chrNW_004624755:6,121,620...6,132,897 		JBrowse link
G Crcp CGRP receptor component acts_upstream_of_or_within ISO (PMID:9322931) MGI PMID:9322931 NCBI chrNW_004624740:8,431,986...8,470,264
Ensembl chrNW_004624740:8,431,970...8,469,765 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:11784785 RGD:70397 NCBI chrNW_004624849:2,484,144...2,528,130
Ensembl chrNW_004624849:2,484,109...2,528,223 		JBrowse link
G Ecrg4 ECRG4 augurin precursor involved_in ISO (PMID:20233222) UniProt PMID:20233222 NCBI chrNW_004624749:9,947,366...9,956,876
Ensembl chrNW_004624749:9,947,188...9,956,983 		JBrowse link
G Gal galanin and GMAP prepropeptide involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12533601) UniProt
MGI
TreeGrafter		 PMID:12533601 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624767:18,195,288...18,210,634
Ensembl chrNW_004624767:18,204,508...18,210,416 		JBrowse link
G Galr2 galanin receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:5,982,870...5,987,756
Ensembl chrNW_004624801:5,983,254...5,985,596 		JBrowse link
G Galr3 galanin receptor 3 ISO RGD PMID:9722565 RGD:728648 NCBI chrNW_004624752:10,089,811...10,091,726 JBrowse link
G Glra1 glycine receptor alpha 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:37,153,348...37,238,201
Ensembl chrNW_004624733:37,153,863...37,235,485 		JBrowse link
G Glra2 glycine receptor alpha 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624944:512,482...704,805
Ensembl chrNW_004624944:512,441...704,786 		JBrowse link
G Glrb glycine receptor beta involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624848:1,301,051...1,383,931
Ensembl chrNW_004624848:1,298,174...1,384,513 		JBrowse link
G Gpr139 G protein-coupled receptor 139 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624782:3,360,589...3,403,112
Ensembl chrNW_004624782:3,362,869...3,402,880 		JBrowse link
G Gpr37 G protein-coupled receptor 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624783:11,291,601...11,319,467
Ensembl chrNW_004624783:11,291,497...11,320,952 		JBrowse link
G Gpr83 G protein-coupled receptor 83 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624735:39,049,652...39,062,198
Ensembl chrNW_004624735:39,049,761...39,061,730 		JBrowse link
G Gpr84 G protein-coupled receptor 84 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624904:2,377,214...2,386,845
Ensembl chrNW_004624904:2,384,088...2,386,816 		JBrowse link
G Grp gastrin releasing peptide involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:8756537) RGD
InterPro
TreeGrafter
MGI		 PMID:8756537 PMID:12419521 GO_REF:0000002 GO_REF:0000118 RGD:728702 NCBI chrNW_004624792:4,623,082...4,633,545
Ensembl chrNW_004624792:4,623,097...4,633,570 		JBrowse link
G Grpr gastrin releasing peptide receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624829:907,386...946,385
Ensembl chrNW_004624829:907,371...939,779 		JBrowse link
G Hcrtr1 hypocretin receptor 1 involved_in ISO (PMID:26950369) RGD
UniProt		 PMID:12697296 PMID:26950369 RGD:730811 NCBI chrNW_004624764:14,861,672...14,872,728
Ensembl chrNW_004624764:14,862,397...14,869,739 		JBrowse link
G Hcrtr2 hypocretin receptor 2 involved_in ISO (PMID:26950369)
(PMID:11282968)		 UniProt
RGD		 PMID:9491897 PMID:11282968 PMID:26950369 RGD:728644 NCBI chrNW_004624850:2,698,806...2,792,194
Ensembl chrNW_004624850:2,699,140...2,795,350 		JBrowse link
G Kiss1r KISS1 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:7,677,467...7,680,508
Ensembl chrNW_004624828:7,677,395...7,680,355 		JBrowse link
G LOC101699147 neuropeptide Y receptor type 6 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624733:9,210,899...9,218,674 JBrowse link
G LOC101710459 probable G-protein coupled receptor 83 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624898:858,962...867,345 JBrowse link
G LOC101715129 neuropeptide Y receptor type 4 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624958:58,828...62,474 JBrowse link
G LOC106007664 neuroendocrine protein 7B2-like involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624733:41,281,864...41,283,460 JBrowse link
G Ltb4r leukotriene B4 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624820:8,187,496...8,196,381
Ensembl chrNW_004624820:8,187,496...8,189,562 		JBrowse link
G Mc2r melanocortin 2 receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624770:20,431,571...20,476,405 JBrowse link
G Mchr1 melanin concentrating hormone receptor 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624752:7,801,867...7,805,791
Ensembl chrNW_004624752:7,801,948...7,805,635 		JBrowse link
G Nmb neuromedin B involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624768:17,903,116...17,906,340
Ensembl chrNW_004624768:17,902,892...17,906,592 		JBrowse link
G Nmbr neuromedin B receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624753:12,017,650...12,029,360
Ensembl chrNW_004624753:12,017,711...12,028,673 		JBrowse link
G Nms neuromedin S acts_upstream_of_or_within ISO PMID:15635449 MGI PMID:15635449 RGD:1359746 NCBI chrNW_004624749:5,294,551...5,342,904
Ensembl chrNW_004624749:5,331,095...5,342,894 		JBrowse link
G Nmu neuromedin U acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:15635449 MGI
TreeGrafter		 PMID:15635449 GO_REF:0000118 RGD:1359746 NCBI chrNW_004624761:13,823,752...13,850,756
Ensembl chrNW_004624761:13,824,144...13,848,219 		JBrowse link
G Nmur1 neuromedin U receptor 1 acts_upstream_of_or_within ISO (PMID:15635449) MGI PMID:15635449 NCBI chrNW_004624843:4,655,198...4,659,942 JBrowse link
G Nmur2 neuromedin U receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15635449) TreeGrafter
MGI		 PMID:15635449 GO_REF:0000118 NCBI chrNW_004624733:36,597,310...36,612,589
Ensembl chrNW_004624733:36,597,431...36,611,439 		JBrowse link
G Npb neuropeptide B involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624801:10,742,517...10,744,972
Ensembl chrNW_004624801:10,744,413...10,744,811 		JBrowse link
G Npbwr2 neuropeptides B and W receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:29,722,947...29,725,714
Ensembl chrNW_004624741:29,723,997...29,725,007 		JBrowse link
G Npffr1 neuropeptide FF receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624754:4,390,049...4,410,208
Ensembl chrNW_004624754:4,396,759...4,406,078 		JBrowse link
G Nppa natriuretic peptide A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624818:1,147,654...1,149,722
Ensembl chrNW_004624818:1,147,974...1,148,927 		JBrowse link
G Npvf neuropeptide VF precursor involved_in ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:11481330 GO_REF:0000002 GO_REF:0000118 RGD:628488 NCBI chrNW_004624739:5,321,831...5,323,710
Ensembl chrNW_004624739:5,321,132...5,325,519 		JBrowse link
G Npy neuropeptide Y involved_in ISO
IEA		 RGD
UniProt
TreeGrafter		 PMID:15703301 PMID:16040808 GO_REF:0000043 GO_REF:0000118 RGD:1580180 RGD:1580181 NCBI chrNW_004624739:6,277,704...6,285,454
Ensembl chrNW_004624739:6,277,612...6,285,397 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1353743|PMID:10698177) GOC
GOC		 PMID:10698177 GO_REF:0000108 MGI:1353743 NCBI chrNW_004624758:13,542,467...13,545,106
Ensembl chrNW_004624758:13,536,493...13,545,599 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624848:3,049,009...3,054,548
Ensembl chrNW_004624848:3,048,413...3,054,495 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624758:13,518,722...13,521,292
Ensembl chrNW_004624758:13,518,951...13,524,840 		JBrowse link
G Nts neurotensin involved_in ISO (PMID:11294867)
(PMID:21806946)		 UniProt
ARUK-UCL		 PMID:11294867 PMID:21806946 NCBI chrNW_004624837:5,035,237...5,045,560
Ensembl chrNW_004624837:5,035,159...5,045,651 		JBrowse link
G Ntsr1 neurotensin receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:28,504,814...28,543,592
Ensembl chrNW_004624741:28,505,037...28,544,122 		JBrowse link
G Ntsr2 neurotensin receptor 2 acts_upstream_of_or_within ISO (MGI:82706|PMID:8795617) GOC PMID:8795617 MGI:82706 NCBI chrNW_004624865:4,302,755...4,310,644
Ensembl chrNW_004624865:4,302,513...4,313,916 		JBrowse link
G Oprd1 opioid receptor delta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8393575) TreeGrafter
MGI
Ensembl		 PMID:8393575 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624764:12,604,051...12,676,368
Ensembl chrNW_004624764:12,604,164...12,676,279 		JBrowse link
G Oprk1 opioid receptor kappa 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624735:2,301,248...2,325,678
Ensembl chrNW_004624735:2,301,101...2,325,684 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:29,713,937...29,720,617
Ensembl chrNW_004624741:29,714,477...29,720,716 		JBrowse link
G Oprm1 opioid receptor mu 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624785:4,147,079...4,195,712
Ensembl chrNW_004624785:4,032,689...4,196,186 		JBrowse link
G Pdyn prodynorphin involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624741:3,239,101...3,253,507
Ensembl chrNW_004624741:3,237,942...3,253,503 		JBrowse link
G Penk proenkephalin involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624886:3,595,485...3,613,117
Ensembl chrNW_004624886:3,595,450...3,613,593 		JBrowse link
G Pnoc prepronociceptin involved_in ISO
IEA		 RGD
InterPro
UniProt
TreeGrafter		 PMID:11826101 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 RGD:633635 NCBI chrNW_004624758:23,007,530...23,026,962
Ensembl chrNW_004624758:23,007,573...23,028,704 		JBrowse link
G Ppy pancreatic polypeptide involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:908,495...909,435 JBrowse link
G Prlhr prolactin releasing hormone receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624737:28,093,837...28,099,377
Ensembl chrNW_004624737:28,094,507...28,095,941 		JBrowse link
G Prokr1 prokineticin receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624762:4,667,733...4,679,878
Ensembl chrNW_004624762:4,667,641...4,679,911 		JBrowse link
G Prokr2 prokineticin receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:6,270,098...6,281,147
Ensembl chrNW_004624741:6,270,002...6,281,182 		JBrowse link
G Pyy peptide YY involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:887,963...903,315
Ensembl chrNW_004624795:902,260...903,409 		JBrowse link
G Qrfp pyroglutamylated RFamide peptide involved_in IEA TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624760:4,873,578...4,874,921 JBrowse link
G Qrfpr pyroglutamylated RFamide peptide receptor involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624777:1,420,050...1,484,518
Ensembl chrNW_004624777:1,419,637...1,484,608 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (MGI:5514088|PMID:23800469)
(PMID:23800469)		 UniProt PMID:23800469 MGI:5514088 NCBI chrNW_004624848:3,968,845...4,184,740
Ensembl chrNW_004624848:3,968,362...4,182,885 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Scg5 secretogranin V involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624804:1,660,371...1,711,169 JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:11294867) UniProt PMID:11294867 NCBI chrNW_004624880:3,579,783...3,749,958
Ensembl chrNW_004624880:3,583,838...3,749,930 		JBrowse link
G Sort1 sortilin 1 involved_in ISO (PMID:9756851) BHF-UCL PMID:9756851 NCBI chrNW_004624772:5,044,948...5,123,300
Ensembl chrNW_004624772:5,049,045...5,123,365 		JBrowse link
G Sstr1 somatostatin receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:68738|PMID:7929134), (PMID:9166719) GOC
TreeGrafter		 PMID:7929134 PMID:9166719 GO_REF:0000118 MGI:68738 NCBI chrNW_004624813:7,538,104...7,543,836
Ensembl chrNW_004624813:7,539,304...7,540,479 		JBrowse link
G Sstr2 somatostatin receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:68738|PMID:7929134), (PMID:9166719) TreeGrafter
MGI		 PMID:7929134 PMID:9166719 GO_REF:0000118 MGI:68738 NCBI chrNW_004624801:3,198,137...3,205,936
Ensembl chrNW_004624801:3,198,204...3,206,481 		JBrowse link
G Sstr3 somatostatin receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:10,623,360...10,626,759
Ensembl chrNW_004624752:10,619,078...10,626,754 		JBrowse link
G Sstr5 somatostatin receptor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624913:1,812,539...1,832,566
Ensembl chrNW_004624913:1,825,435...1,832,501 		JBrowse link
G Tac1 tachykinin precursor 1 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624813:4,542,226...4,550,378
Ensembl chrNW_004624813:4,542,011...4,550,486 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase acts_upstream_of_or_within ISO (PMID:9331176) MGI PMID:9331176 NCBI chrNW_004624804:8,711,487...8,729,025
Ensembl chrNW_004624804:8,710,821...8,728,072 		JBrowse link
G Ucn urocortin ISO RGD PMID:11784785 RGD:70397 NCBI chrNW_004624738:9,393,004...9,393,966
Ensembl chrNW_004624738:9,393,329...9,393,706 		JBrowse link
galanin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galr2 galanin receptor 2 involved_in ISO (PMID:9832121) GO_Central PMID:9832121 NCBI chrNW_004624801:5,982,870...5,987,756
Ensembl chrNW_004624801:5,983,254...5,985,596 		JBrowse link
G Galr3 galanin receptor 3 involved_in ISO (PMID:9832121) GO_Central PMID:9832121 NCBI chrNW_004624752:10,089,811...10,091,726 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14252
      signal transduction 5427
        G protein-coupled receptor signaling pathway 1378
          neuropeptide signaling pathway 75
            galanin-activated signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10620
      regulation of biological process 10303
        signaling 5917
          signal transduction 5427
            G protein-coupled receptor signaling pathway 1378
              neuropeptide signaling pathway 75
                galanin-activated signaling pathway 2
paths to the root