Agrp (agouti related neuropeptide) - Rat Genome Database

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Gene: Agrp (agouti related neuropeptide) Heterocephalus glaber
Analyze
Symbol: Agrp
Name: agouti related neuropeptide
RGD ID: 18906862
Description: ENCODES a protein that exhibits neuropeptide hormone activity (inferred); signaling receptor binding (inferred); type 1 melanocortin receptor binding (inferred); INVOLVED IN adult feeding behavior (ortholog); circadian rhythm (ortholog); eating behavior (ortholog); PARTICIPATES IN altered melanocortin system pathway; melanocortin system pathway; obesity pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); Hyperphagia (ortholog); FOUND IN extracellular space (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: agouti related protein homolog; Agouti-related protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,826,545 - 18,827,299 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,826,206 - 18,827,453 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Agrp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,826,545 - 18,827,299 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,826,206 - 18,827,453 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AGRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,482,571 - 67,483,547 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,482,571 - 67,483,547 (-)EnsemblGRCh38hg38GRCh38
GRCh371667,516,474 - 67,517,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,073,975 - 66,075,217 (-)NCBINCBI36Build 36hg18NCBI36
Build 341666,073,974 - 66,074,805NCBI
Celera1652,024,676 - 52,025,918 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,389,602 - 53,390,844 (-)NCBIHuRef
CHM1_11668,923,856 - 68,925,098 (-)NCBICHM1_1
T2T-CHM13v2.01673,277,343 - 73,278,319 (-)NCBIT2T-CHM13v2.0
Agrp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,293,327 - 106,306,477 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,293,330 - 106,364,025 (-)EnsemblGRCm39 Ensembl
GRCm388105,566,695 - 105,579,845 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,566,698 - 105,637,393 (-)EnsemblGRCm38mm10GRCm38
MGSCv378108,090,598 - 108,092,198 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,455,827 - 108,457,427 (-)NCBIMGSCv36mm8
Celera8109,789,930 - 109,791,530 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Agrp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,357,899 - 50,396,758 (-)NCBIGRCr8
mRatBN7.21933,447,992 - 33,481,602 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,447,992 - 33,449,584 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,263,577 - 40,265,169 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,916,914 - 40,918,506 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,214,688 - 43,216,280 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,525,941 - 37,584,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,526,419 - 37,528,011 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,391,845 - 48,406,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,386,682 - 35,388,274 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,391,672 - 35,392,244 (-)NCBI
Celera1932,876,306 - 32,877,927 (-)NCBICelera
Cytogenetic Map19q12NCBI
Agrp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,165,120 - 9,166,789 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,165,120 - 9,166,789 (+)NCBIChiLan1.0ChiLan1.0
AGRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,011,780 - 77,013,321 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,924,427 - 82,925,968 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,827,532 - 47,872,727 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,216,008 - 67,217,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,216,008 - 67,217,258 (-)Ensemblpanpan1.1panPan2
AGRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,924,249 - 81,926,510 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,925,055 - 81,925,845 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,914,032 - 81,915,572 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,359,662 - 82,361,202 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,360,349 - 82,361,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,185,812 - 82,187,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,866,912 - 81,868,452 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,510,362 - 82,511,902 (+)NCBIUU_Cfam_GSD_1.0
Agrp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,652,027 - 41,660,973 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,927,985 - 17,937,147 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,927,991 - 17,929,377 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,132,615 - 28,134,900 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,132,614 - 28,135,594 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,399,704 - 25,401,437 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGRP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,972,728 - 59,974,728 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,973,922 - 59,974,660 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,722,627 - 22,723,740 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014427   ⟹   ENSHGLP00000014283
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474618,826,545 - 18,827,299 (+)Ensembl
RefSeq Acc Id: XM_004843031   ⟹   XP_004843088
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474618,826,206 - 18,827,453 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004843088 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17024 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014283
  ENSHGLP00100022739
Reference Protein Sequences
RefSeq Acc Id: XP_004843088   ⟸   XM_004843031
- UniProtKB: G5C663 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014283   ⟸   ENSHGLT00000014427


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010211 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100016720 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014427 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100022975 UniProtKB/TrEMBL
Gene3D-CATH 4.10.760.10 UniProtKB/TrEMBL
InterPro Agouti UniProtKB/TrEMBL
  Agouti_dom UniProtKB/TrEMBL
  Agouti_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101711496 UniProtKB/TrEMBL
NCBI Gene Agrp ENTREZGENE
PANTHER AGOUTI-RELATED PROTEIN UniProtKB/TrEMBL
  PTHR16551 UniProtKB/TrEMBL
Pfam Agouti UniProtKB/TrEMBL
PROSITE AGOUTI_1 UniProtKB/TrEMBL
  AGOUTI_2 UniProtKB/TrEMBL
SMART Agouti UniProtKB/TrEMBL
Superfamily-SCOP SSF57055 UniProtKB/TrEMBL
UniProt G5C663 ENTREZGENE, UniProtKB/TrEMBL