Pnoc (prepronociceptin) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Pnoc (prepronociceptin) Heterocephalus glaber
Analyze
Symbol: Pnoc
Name: prepronociceptin
RGD ID: 18900345
Description: ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); female pregnancy (ortholog); neuron-neuron synaptic transmission (ortholog); ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign familial infantile seizures 6 (ortholog); fetal alcohol spectrum disorder (ortholog); FOUND IN synaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prepronociceptin preproprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475823,007,573 - 23,028,704 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475823,007,530 - 23,026,962 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pnoc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475823,007,573 - 23,028,704 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475823,007,530 - 23,026,962 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PNOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38828,316,988 - 28,343,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl828,316,986 - 28,343,355 (+)EnsemblGRCh38hg38GRCh38
GRCh37828,174,785 - 28,200,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,230,568 - 28,256,787 (+)NCBINCBI36Build 36hg18NCBI36
Build 34828,230,567 - 28,256,786NCBI
Celera827,134,504 - 27,160,720 (+)NCBICelera
Cytogenetic Map8p21.1NCBI
HuRef826,719,942 - 26,746,164 (+)NCBIHuRef
CHM1_1828,376,658 - 28,402,833 (+)NCBICHM1_1
T2T-CHM13v2.0828,595,062 - 28,621,518 (+)NCBIT2T-CHM13v2.0
Pnoc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391465,638,931 - 65,662,908 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1465,638,122 - 65,662,921 (-)EnsemblGRCm39 Ensembl
GRCm381465,400,673 - 65,425,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1465,400,673 - 65,425,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv371466,019,510 - 66,044,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361464,354,783 - 64,379,319 (-)NCBIMGSCv36mm8
Celera1463,152,191 - 63,176,787 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.33NCBI
Pnoc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81543,800,240 - 43,827,841 (-)NCBIGRCr8
mRatBN7.21539,624,635 - 39,652,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1539,624,641 - 39,651,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1541,488,469 - 41,501,440 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01542,638,659 - 42,651,630 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01541,085,000 - 41,097,863 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01548,805,841 - 48,833,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1548,805,228 - 48,833,285 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01552,547,677 - 52,574,687 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41544,822,635 - 44,835,637 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11544,838,334 - 44,851,337 (-)NCBI
Celera1539,298,658 - 39,311,512 (-)NCBICelera
Cytogenetic Map15p12NCBI
Pnoc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540350,735,390 - 50,755,902 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540350,735,567 - 50,755,892 (+)NCBIChiLan1.0ChiLan1.0
PNOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2746,856,738 - 46,883,138 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1822,571,113 - 22,597,566 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0827,596,413 - 27,622,844 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1824,796,490 - 24,822,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl824,796,638 - 24,822,758 (+)Ensemblpanpan1.1panPan2
PNOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12529,223,758 - 29,246,487 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2529,224,092 - 29,245,851 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2529,873,540 - 29,896,041 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02529,382,377 - 29,404,891 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2529,382,715 - 29,404,498 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12529,342,437 - 29,364,950 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02529,226,990 - 29,249,199 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02529,393,029 - 29,415,545 (-)NCBIUU_Cfam_GSD_1.0
Pnoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049437,451,235 - 7,473,199 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366751,113,435 - 1,134,910 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366751,113,435 - 1,134,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1412,101,698 - 12,133,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11412,101,223 - 12,134,174 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21413,256,659 - 13,288,651 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PNOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1826,418,473 - 26,444,689 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl826,418,815 - 26,444,677 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605215,687,564 - 15,713,855 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000012990   ⟹   ENSHGLP00000012853
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475823,007,573 - 23,028,704 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000012991   ⟹   ENSHGLP00000012854
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475823,007,573 - 23,028,704 (+)Ensembl
RefSeq Acc Id: XM_004848410   ⟹   XP_004848467
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475823,007,900 - 23,026,956 (+)NCBI
RefSeq Acc Id: XM_004848411   ⟹   XP_004848468
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475823,007,908 - 23,026,955 (+)NCBI
RefSeq Acc Id: XM_004848412   ⟹   XP_004848469
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475823,007,530 - 23,026,962 (+)NCBI
RefSeq Acc Id: XM_004848413   ⟹   XP_004848470
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475823,007,534 - 23,026,958 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004848467 (Get FASTA)   NCBI Sequence Viewer  
  XP_004848468 (Get FASTA)   NCBI Sequence Viewer  
  XP_004848469 (Get FASTA)   NCBI Sequence Viewer  
  XP_004848470 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG38279 (Get FASTA)   NCBI Sequence Viewer  
  JAO01322 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004848469   ⟸   XM_004848412
- Peptide Label: isoform X3
- UniProtKB: G5B4Z8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848470   ⟸   XM_004848413
- Peptide Label: isoform X4
- UniProtKB: G5B4Z8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848467   ⟸   XM_004848410
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004848468   ⟸   XM_004848411
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JX05 (UniProtKB/TrEMBL),   G5B4Z8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000012854   ⟸   ENSHGLT00000012991
RefSeq Acc Id: ENSHGLP00000012853   ⟸   ENSHGLT00000012990


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009187 Ensembl
InterPro Nociceptin UniProtKB/TrEMBL
  Opioid_neupept UniProtKB/TrEMBL
NCBI Gene Pnoc ENTREZGENE
PANTHER PREPRONOCICEPTIN UniProtKB/TrEMBL
  PTHR11438 UniProtKB/TrEMBL
Pfam Opiods_neuropep UniProtKB/TrEMBL
PRINTS OPIOIDPRCRSR UniProtKB/TrEMBL
  ORPHNNPRCRSR UniProtKB/TrEMBL
PROSITE OPIOIDS_PRECURSOR UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
UniProt A0A0P6JX05 ENTREZGENE, UniProtKB/TrEMBL
  G5B4Z8 ENTREZGENE, UniProtKB/TrEMBL
  Q99NP7_HETGA UniProtKB/TrEMBL