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ONTOLOGY REPORT - ANNOTATIONS

Term:rough endoplasmic reticulum
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Accession:GO:0005791 term browser browse the term
Definition:The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
Synonyms:exact_synonym: RER;   rough ER
 xref: NIF_Subcellular:sao1881364067;   Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum


show annotations for term's descendants           Sort by:
rough endoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA4 carbonic anhydrase 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:37,962,951...37,972,443
Ensembl chr12:37,962,943...37,972,509 		JBrowse link
G CCDC47 coiled-coil domain containing 47 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,165,268...15,186,141
Ensembl chr12:15,165,405...15,186,104 		JBrowse link
G CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:15,910,645...16,569,643
Ensembl chr 7:15,910,666...16,626,276 		JBrowse link
G CKAP4 cytoskeleton associated protein 4 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:14,021,131...14,031,196
Ensembl chr 5:14,021,131...14,030,039 		JBrowse link
G EPHA5 EPH receptor A5 located_in ISO (PMID:10375373) UniProt PMID:10375373 NCBI chr 8:63,285,006...63,604,734
Ensembl chr 8:63,287,711...63,604,734 		JBrowse link
G F12 coagulation factor XII is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G FKRP fukutin related protein located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,627,466...52,639,255
Ensembl chr 6:52,627,471...52,639,253 		JBrowse link
G HCRT hypocretin neuropeptide precursor located_in IEA UniProt GO_REF:0000044 NCBI chr12:20,588,597...20,589,991
Ensembl chr12:20,588,027...20,589,988 		JBrowse link
G HGFAC HGF activator located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:2,077,164...2,084,506
Ensembl chr 8:2,077,176...2,084,507 		JBrowse link
G HM13 histocompatibility minor 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:35,248,575...35,288,431
Ensembl chr17:35,248,570...35,288,539 		JBrowse link
G LIN28A lin-28 homolog A located_in IEA Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 NCBI chr 6:83,806,178...83,818,550
Ensembl chr 6:83,806,056...83,818,633 		JBrowse link
G LOC100518848 40S ribosomal protein S21 located_in IEA UniProt GO_REF:0000044 Ensembl chr17:61,763,574...61,764,832 JBrowse link
G LRAT lecithin retinol acyltransferase is_active_in
located_in		 IBA
ISO		 PMID:18544127 GO_Central
UniProt		 PMID:18544127 GO_REF:0000033 RGD:6893660 NCBI chr 8:74,412,226...74,428,713
Ensembl chr 8:74,409,461...74,419,681 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor located_in ISO (PMID:18816594) UniProt PMID:18816594 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G MYOC myocilin located_in IEA UniProt GO_REF:0000044 NCBI chr 9:114,087,370...114,098,765
Ensembl chr 9:114,087,378...114,098,745 		JBrowse link
G PKM pyruvate kinase M1/2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,971,807...61,032,780
Ensembl chr 7:60,975,667...61,004,316
Ensembl chr 7:60,975,667...61,004,316 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 located_in IEA UniProt GO_REF:0000044 NCBI chr13:86,402,673...86,513,167
Ensembl chr13:86,401,244...86,513,105 		JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 located_in IEA UniProt GO_REF:0000044 NCBI chr 3:8,911,787...8,919,525
Ensembl chr 3:8,911,791...8,919,516 		JBrowse link
G PSEN1 presenilin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PTGDS prostaglandin D2 synthase located_in ISS
IEA		 UniProt GO_REF:0000024 GO_REF:0000044
G RAB14 RAB14, member RAS oncogene family located_in ISO PMID:15004230 UniProt PMID:15004230 RGD:8554557 NCBI chr 1:261,228,112...261,256,913
Ensembl chr 1:261,229,535...261,256,791 		JBrowse link
G RANGRF RAN guanine nucleotide release factor located_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,484,584...53,486,716
Ensembl chr12:53,485,265...53,486,713 		JBrowse link
G RPL18 ribosomal protein L18 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:53,974,353...53,978,681
Ensembl chr 6:53,974,309...53,978,544 		JBrowse link
G RPL27 ribosomal protein L27 located_in IEA UniProt GO_REF:0000044 NCBI chr12:19,892,210...19,894,202
Ensembl chr12:19,892,217...19,894,504 		JBrowse link
G RPL4 ribosomal protein L4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:164,476,269...164,481,765
Ensembl chr 1:164,475,357...164,481,534 		JBrowse link
G RPL6 ribosomal protein L6 located_in IEA UniProt GO_REF:0000044 NCBI chr14:39,302,447...39,309,239
Ensembl chr14:39,303,350...39,309,236 		JBrowse link
G RPN1 ribophorin I located_in IEA Ensembl GO_REF:0000107 NCBI chr13:71,892,600...71,908,772
Ensembl chr13:71,892,002...71,908,932 		JBrowse link
G RPS21 ribosomal protein S21 located_in IEA UniProt GO_REF:0000044 NCBI chr17:61,763,606...61,764,823
Ensembl chr17:61,763,574...61,764,832 		JBrowse link
G RPS23 ribosomal protein S23 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:90,679,038...90,680,681
Ensembl chr 2:90,679,000...90,680,765 		JBrowse link
G RPS26 ribosomal protein S26 located_in IEA UniProt GO_REF:0000044 NCBI chr 5:21,431,656...21,433,691
Ensembl chr 5:21,431,937...21,433,697 		JBrowse link
G RPS28 ribosomal protein S28 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:70,953,706...70,954,862
Ensembl chr 2:70,953,708...70,954,775 		JBrowse link
G RPS29 ribosomal protein S29 located_in IEA UniProt GO_REF:0000044 NCBI chr 1:179,454,923...179,456,847
Ensembl chr 1:179,454,928...179,461,631 		JBrowse link
G SEC62 SEC62 homolog, preprotein translocation factor located_in ISS UniProt GO_REF:0000024 NCBI chr13:108,660,486...108,688,307
Ensembl chr13:108,660,450...108,691,595 		JBrowse link
G SPPL3 signal peptide peptidase like 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,699,931...40,870,288
Ensembl chr14:40,699,937...40,822,761 		JBrowse link
G STX17 syntaxin 17 NOT|located_in ISO (PMID:10930465) UniProt PMID:10930465 NCBI chr 1:241,657,463...241,785,270
Ensembl chr 1:241,657,506...241,765,783 		JBrowse link
G SUCO SUN domain containing ossification factor located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:114,916,957...115,007,979
Ensembl chr 9:114,916,855...115,007,972 		JBrowse link
G TMCC1 transmembrane and coiled-coil domain family 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:69,039,173...69,223,806
Ensembl chr13:69,036,428...69,290,098 		JBrowse link
G TMEM97 transmembrane protein 97 located_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr12:44,603,764...44,609,935
Ensembl chr12:44,604,021...44,609,999 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,193 		JBrowse link
cytoplasmic side of rough endoplasmic reticulum membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALG5 ALG5 dolichyl-phosphate beta-glucosyltransferase is_active_in
located_in		 ISO
IEA		 (PMID:10359825) UniProt
Ensembl		 PMID:10359825 GO_REF:0000107 NCBI chr11:12,777,549...12,815,969
Ensembl chr11:12,777,552...12,816,008 		JBrowse link
G FBXO30 F-box protein 30 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,806,363...19,893,350
Ensembl chr 1:19,806,765...19,893,339 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 ISO gonadotropin-releasing hormone-associated peptide RGD PMID:2183089 RGD:9685146 NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035 		JBrowse link
G ICMT isoprenylcysteine carboxyl methyltransferase located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 6:67,116,943...67,125,908
Ensembl chr 6:67,116,946...67,123,810 		JBrowse link
G LOC100518848 40S ribosomal protein S21 located_in IDA (PMID:24930395) UniProt PMID:24930395 Ensembl chr17:61,763,574...61,764,832 JBrowse link
G RPL10 ribosomal protein L10 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr  X:124,927,249...124,929,791
Ensembl chr  X:124,926,772...124,929,791 		JBrowse link
G RPL11 ribosomal protein L11 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G RPL14 ribosomal protein L14 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr13:24,691,893...24,698,685
Ensembl chr13:24,691,893...24,699,363 		JBrowse link
G RPL22 ribosomal protein L22 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 6:67,092,892...67,102,086
Ensembl chr 6:67,092,890...67,102,086 		JBrowse link
G RPL23 ribosomal protein L23 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr12:23,279,965...23,285,538
Ensembl chr12:23,279,965...23,285,515 		JBrowse link
G RPL27 ribosomal protein L27 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr12:19,892,210...19,894,202
Ensembl chr12:19,892,217...19,894,504 		JBrowse link
G RPL29 ribosomal protein L29 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr13:34,119,541...34,121,842
Ensembl chr13:34,119,539...34,121,859 		JBrowse link
G RPL31 ribosomal protein L31 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 3:53,289,993...53,295,387
Ensembl chr 3:53,281,339...53,295,304 		JBrowse link
G RPL32 ribosomal protein L32 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr13:68,788,109...68,793,265
Ensembl chr13:68,786,856...68,793,204 		JBrowse link
G RPL35 ribosomal protein L35 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 1:265,637,266...265,642,278
Ensembl chr 1:265,636,637...265,645,593 		JBrowse link
G RPL36AL ribosomal protein L36a like located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 1:179,476,638...179,477,820
Ensembl chr 1:179,476,640...179,479,147 		JBrowse link
G RPL6 ribosomal protein L6 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr14:39,302,447...39,309,239
Ensembl chr14:39,303,350...39,309,236 		JBrowse link
G RPS15 ribosomal protein S15 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 2:77,043,329...77,044,749
Ensembl chr 2:77,043,329...77,046,747 		JBrowse link
G RPS16 ribosomal protein S16 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 6:48,085,684...48,088,368
Ensembl chr 6:48,085,678...48,088,423 		JBrowse link
G RPS17 ribosomal protein S17 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 7:52,386,342...52,389,003
Ensembl chr 7:52,386,036...52,390,599 		JBrowse link
G RPS18 ribosomal protein S18 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 7:29,638,856...29,642,912
Ensembl chr 7:29,638,833...29,642,912 		JBrowse link
G RPS20 ribosomal protein S20 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 4:75,762,209...75,763,449
Ensembl chr 4:75,762,209...75,769,955 		JBrowse link
G RPS21 ribosomal protein S21 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr17:61,763,606...61,764,823
Ensembl chr17:61,763,574...61,764,832 		JBrowse link
G RPS23 ribosomal protein S23 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 2:90,679,038...90,680,681
Ensembl chr 2:90,679,000...90,680,765 		JBrowse link
G RPS26 ribosomal protein S26 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 5:21,431,656...21,433,691
Ensembl chr 5:21,431,937...21,433,697 		JBrowse link
G RPS28 ribosomal protein S28 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 2:70,953,706...70,954,862
Ensembl chr 2:70,953,708...70,954,775 		JBrowse link
G RPS29 ribosomal protein S29 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 1:179,454,923...179,456,847
Ensembl chr 1:179,454,928...179,461,631 		JBrowse link
G RPS3 ribosomal protein S3 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,624,990...9,630,401 		JBrowse link
G RPSA ribosomal protein SA located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr13:24,072,551...24,081,536
Ensembl chr13:24,072,527...24,081,541 		JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 located_in IDA (PMID:24930395) UniProt PMID:24930395 NCBI chr 2:59,238,802...59,241,512
Ensembl chr 2:59,238,906...59,240,274 		JBrowse link
rough endoplasmic reticulum lumen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase ISO RGD PMID:4413686 RGD:11560526 (All species) (All species) NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:10903535 RGD:8662311 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 is_active_in
located_in		 ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:8223699 GO_REF:0000033 GO_REF:0000107 RGD:1641935 NCBI chr 8:2,129,492...2,145,632
Ensembl chr 8:2,125,405...2,145,647 		JBrowse link
G LYZ lysozyme ISO RGD PMID:9208328 RGD:1599861 NCBI chr 5:33,612,593...33,618,953
Ensembl chr 5:33,612,567...33,618,945 		JBrowse link
G RESP18 regulated endocrine specific protein 18 ISO RGD PMID:8132649 RGD:69957 NCBI chr15:121,364,165...121,371,430 JBrowse link
G VTN vitronectin ISO RGD PMID:10192552 RGD:10003091 NCBI chr12:44,650,532...44,653,916
Ensembl chr12:44,650,534...44,655,355 		JBrowse link
rough endoplasmic reticulum membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B ISO RGD PMID:234468 RGD:2313431 NCBI chr 1:243,127,870...243,141,504
Ensembl chr 1:243,110,585...243,141,418 		JBrowse link
G CCDC47 coiled-coil domain containing 47 located_in IEA UniProt GO_REF:0000044 NCBI chr12:15,165,268...15,186,141
Ensembl chr12:15,165,405...15,186,104 		JBrowse link
G MACO1 macoilin 1 located_in
is_active_in		 IEA
IBA
ISS		 UniProt
GO_Central
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr 6:82,934,083...82,995,688
Ensembl chr 6:82,933,826...82,997,142 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta located_in IEA UniProt GO_REF:0000044 NCBI chr 4:97,918,234...97,949,929
Ensembl chr 4:97,918,245...97,949,931 		JBrowse link
G PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:71,987,938...72,019,712
Ensembl chr 6:71,988,459...72,021,804 		JBrowse link
G RHO rhodopsin ISO RGD PMID:2525480 RGD:6893558 NCBI chr13:68,908,578...68,913,651
Ensembl chr13:68,908,578...68,913,651 		JBrowse link
G TMEM97 transmembrane protein 97 located_in IEA UniProt GO_REF:0000044 NCBI chr12:44,603,764...44,609,935
Ensembl chr12:44,604,021...44,609,999 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,810,726...41,832,818
Ensembl chr  X:41,814,101...41,832,812 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,193 		JBrowse link
Sec61 translocon complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL6IP1 ARL6 interacting reticulophagy regulator 1 part_of IBA GO_Central GO_REF:0000033 NCBI chr 3:26,759,365...26,770,325
Ensembl chr 3:26,653,979...26,770,322 		JBrowse link
G SEC61A1 SEC61 translocon subunit alpha 1 part_of IBA GO_Central GO_REF:0000033 NCBI chr13:72,254,462...72,276,484
Ensembl chr13:72,254,464...72,269,914 		JBrowse link
G SEC61A2 SEC61 translocon subunit alpha 2 part_of IBA GO_Central GO_REF:0000033 NCBI chr10:59,790,073...59,817,039
Ensembl chr10:59,773,852...59,817,010 		JBrowse link
G SEC61B SEC61 translocon subunit beta part_of IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:240,985,173...240,991,820
Ensembl chr 1:240,985,162...240,992,976 		JBrowse link
G SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase part_of IBA GO_Central GO_REF:0000033 NCBI chr 3:26,653,819...26,758,268
Ensembl chr 3:26,653,979...26,770,322 		JBrowse link
G SSR4 signal sequence receptor subunit 4 ISO RGD PMID:7916687 RGD:61758 NCBI chr  X:124,537,545...124,541,635
Ensembl chr  X:124,537,540...124,541,637 		JBrowse link
Sec62/Sec63 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SEC63 SEC63 homolog, protein translocation regulator part_of IBA GO_Central GO_REF:0000033 NCBI chr 1:74,003,428...74,078,605
Ensembl chr 1:74,000,688...74,078,582 		JBrowse link
signal recognition particle receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100738822 retinitis pigmentosa 9 protein part_of ISO (PMID:15652350) UniProt PMID:15652350 NCBI chr18:40,397,551...40,415,127
Ensembl chr18:40,539,046...40,564,228 		JBrowse link
G SRPRA SRP receptor subunit alpha part_of IEA InterPro GO_REF:0000002 NCBI chr 9:53,358,522...53,365,085
Ensembl chr 9:53,358,534...53,365,653 		JBrowse link
G SRPRB SRP receptor subunit beta part_of IBA GO_Central GO_REF:0000033 NCBI chr13:74,976,030...75,010,200
Ensembl chr13:74,975,677...75,010,212 		JBrowse link
Ssh1 translocon complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SEC61G SEC61 translocon subunit gamma part_of IBA GO_Central GO_REF:0000033 NCBI chr 9:139,128,287...139,135,831
Ensembl chr 9:139,128,296...139,135,727 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18492
    cellular anatomical structure 18269
      endomembrane system 3943
        endoplasmic reticulum 1627
          rough endoplasmic reticulum 84
            rough endoplasmic reticulum cisterna 0
            rough endoplasmic reticulum lumen 6
            rough endoplasmic reticulum membrane + 50
Path 2
Term Annotations click to browse term
  cellular_component 18492
    cellular anatomical structure 18269
      intracellular anatomical structure 13307
        intracellular organelle 11880
          intracellular membrane-bounded organelle 10719
            endoplasmic reticulum 1627
              rough endoplasmic reticulum 84
                rough endoplasmic reticulum cisterna 0
                rough endoplasmic reticulum lumen 6
                rough endoplasmic reticulum membrane + 50
paths to the root