RANGRF (RAN guanine nucleotide release factor) - Rat Genome Database

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Gene: RANGRF (RAN guanine nucleotide release factor) Sus scrofa
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Symbol: RANGRF
Name: RAN guanine nucleotide release factor
RGD ID: 14073069
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); small GTPase binding (inferred); sodium channel regulator activity (inferred); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); positive regulation of protein localization to cell surface (inferred); positive regulation of protein localization to plasma membrane (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); Cardiac Arrhythmias (ortholog); Diamond-Blackfan anemia (ortholog); FOUND IN caveola (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,485,280 - 53,525,756 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,484,584 - 53,486,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,960,779 - 55,962,215 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890  


Genomics

Comparative Map Data
RANGRF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,485,280 - 53,525,756 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,484,584 - 53,486,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,960,779 - 55,962,215 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RANGRF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,288,670 - 8,290,087 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl178,288,654 - 8,290,092 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,191,988 - 8,193,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,132,714 - 8,134,130 (+)NCBINCBI36hg18NCBI36
Celera178,220,823 - 8,222,263 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef178,087,401 - 8,088,841 (+)NCBIHuRef
CHM1_1178,200,890 - 8,202,330 (+)NCBICHM1_1
T2T-CHM13v2.0178,194,912 - 8,196,329 (+)NCBI
Rangrf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,863,310 - 68,866,011 (-)NCBIGRCm39mm39
GRCm39 Ensembl1168,863,310 - 68,866,011 (-)Ensembl
GRCm381168,972,484 - 68,975,185 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,972,484 - 68,975,185 (-)EnsemblGRCm38mm10GRCm38
MGSCv371168,785,989 - 68,787,322 (-)NCBIGRCm37mm9NCBIm37
MGSCv361168,788,682 - 68,790,015 (-)NCBImm8
Celera1175,915,300 - 75,916,633 (-)NCBICelera
Cytogenetic Map11B3NCBI
Rangrf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21053,677,467 - 53,678,880 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1053,677,467 - 53,678,840 (-)Ensembl
Rnor_6.01055,559,049 - 55,560,420 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,559,041 - 55,560,422 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,301,089 - 55,302,460 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,731,343 - 55,732,714 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1052,843,782 - 52,845,153 (-)NCBICelera
Cytogenetic Map10q24NCBI
Rangrf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,622,843 - 8,624,401 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,622,843 - 8,624,401 (-)NCBIChiLan1.0ChiLan1.0
RANGRF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11748,101,744 - 48,103,394 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1748,101,744 - 48,103,394 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01743,369,556 - 43,371,025 (-)NCBIMhudiblu_PPA_v0panPan3
RANGRF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,084,355 - 33,085,810 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,084,397 - 33,085,812 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,220,241 - 33,221,698 (+)NCBI
ROS_Cfam_1.0533,187,232 - 33,188,689 (+)NCBI
ROS_Cfam_1.0 Ensembl533,187,276 - 33,188,691 (+)Ensembl
UMICH_Zoey_3.1533,153,967 - 33,155,423 (+)NCBI
UNSW_CanFamBas_1.0533,109,932 - 33,111,388 (+)NCBI
UU_Cfam_GSD_1.0533,289,666 - 33,291,122 (+)NCBI
Rangrf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,039,669 - 48,041,112 (+)NCBI
SpeTri2.0NW_0049365951,513,855 - 1,515,300 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RANGRF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,654,235 - 7,655,851 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl167,654,439 - 7,655,703 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605913,744,846 - 13,746,467 (-)NCBIVero_WHO_p1.0
Rangrf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,866,834 - 10,867,983 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462478610,866,724 - 10,868,136 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system
High
Medium
Low 2
Below cutoff 3 1 13

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000053159   ⟹   ENSSSCP00000049069
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1253,485,280 - 53,525,756 (+)Ensembl
RefSeq Acc Id: NM_001243369   ⟹   NP_001230298
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11253,485,281 - 53,486,673 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001243370   ⟹   NP_001230299
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11253,485,282 - 53,486,492 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657038   ⟹   XP_005657095
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11253,485,245 - 53,486,716 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021066166   ⟹   XP_020921825
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11253,484,584 - 53,486,716 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001230298 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230299 (Get FASTA)   NCBI Sequence Viewer  
  XP_005657095 (Get FASTA)   NCBI Sequence Viewer  
  XP_020921825 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020921825   ⟸   XM_021066166
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005657095   ⟸   XM_005657038
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001230298   ⟸   NM_001243369
- Peptide Label: isoform 1
- UniProtKB: A0A287AY47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230299   ⟸   NM_001243370
- Peptide Label: isoform 2
- UniProtKB: A0A287ACY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000049069   ⟸   ENSSSCT00000053159


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038726 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005029638 UniProtKB/TrEMBL
  ENSSSCG00015021435 UniProtKB/TrEMBL
  ENSSSCG00025057759 UniProtKB/TrEMBL
  ENSSSCG00030071475 UniProtKB/TrEMBL
  ENSSSCG00035030605 UniProtKB/TrEMBL
  ENSSSCG00040016410 UniProtKB/TrEMBL
  ENSSSCG00045038789 UniProtKB/TrEMBL
  ENSSSCG00050012441 UniProtKB/TrEMBL
  ENSSSCG00055024098 UniProtKB/TrEMBL
  ENSSSCG00060057005 UniProtKB/TrEMBL
  ENSSSCG00065035926 UniProtKB/TrEMBL
  ENSSSCG00070022710 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000049069 UniProtKB/TrEMBL
  ENSSSCP00005029062 UniProtKB/TrEMBL
  ENSSSCP00005029089 UniProtKB/TrEMBL
  ENSSSCP00015011135 UniProtKB/TrEMBL
  ENSSSCP00025034320 UniProtKB/TrEMBL
  ENSSSCP00030046143 UniProtKB/TrEMBL
  ENSSSCP00035016201 UniProtKB/TrEMBL
  ENSSSCP00040009218 UniProtKB/TrEMBL
  ENSSSCP00045047871 UniProtKB/TrEMBL
  ENSSSCP00045047884 UniProtKB/TrEMBL
  ENSSSCP00050006899 UniProtKB/TrEMBL
  ENSSSCP00055037938 UniProtKB/TrEMBL
  ENSSSCP00060033564 UniProtKB/TrEMBL
  ENSSSCP00065021166 UniProtKB/TrEMBL
  ENSSSCP00070038055 UniProtKB/TrEMBL
  ENSSSCP00070038061 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053159 UniProtKB/TrEMBL
  ENSSSCT00005047194 UniProtKB/TrEMBL
  ENSSSCT00005047245 UniProtKB/TrEMBL
  ENSSSCT00015028437 UniProtKB/TrEMBL
  ENSSSCT00025079051 UniProtKB/TrEMBL
  ENSSSCT00030100090 UniProtKB/TrEMBL
  ENSSSCT00035040517 UniProtKB/TrEMBL
  ENSSSCT00040022057 UniProtKB/TrEMBL
  ENSSSCT00045067401 UniProtKB/TrEMBL
  ENSSSCT00045067422 UniProtKB/TrEMBL
  ENSSSCT00050016788 UniProtKB/TrEMBL
  ENSSSCT00055047527 UniProtKB/TrEMBL
  ENSSSCT00060077677 UniProtKB/TrEMBL
  ENSSSCT00065048962 UniProtKB/TrEMBL
  ENSSSCT00070045158 UniProtKB/TrEMBL
  ENSSSCT00070045164 UniProtKB/TrEMBL
InterPro Mog1 UniProtKB/TrEMBL
  Mog1/PsbP_a/b/a-sand UniProtKB/TrEMBL
KEGG Report ssc:100628074 UniProtKB/TrEMBL
NCBI Gene RANGRF ENTREZGENE
PANTHER PTHR15837 UniProtKB/TrEMBL
Pfam Mog1 UniProtKB/TrEMBL
Superfamily-SCOP SSF55724 UniProtKB/TrEMBL
UniProt A0A287ACY1 ENTREZGENE
  A0A287AY47 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V5J6_PIG UniProtKB/TrEMBL
  A0A4X1V932_PIG UniProtKB/TrEMBL
  A0A8D1DNT5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92083 ENTREZGENE