ONTOLOGY REPORT - ANNOTATIONS |
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Term: | DNA damage checkpoint signaling |
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Accession: | GO:0000077
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browse the term
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Definition: | A signal transduction process that contributes to a DNA damage checkpoint. |
Synonyms: | exact_synonym: | DNA damage checkpoint; signal transduction involved in DNA damage checkpoint |
| narrow_synonym: | DNA damage response, signal transduction resulting in cell cycle arrest |
| alt_id: | GO:0072422 |
| xref: | Wikipedia:DNA_damage_checkpoint; Wikipedia:Postreplication_checkpoint |
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GViewer not supported for the selected species.
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ATM |
ATM serine/threonine kinase |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:12937170) |
MGI Ensembl |
PMID:12937170 |
GO_REF:0000107 |
NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520
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ATR |
ATR serine/threonine kinase |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:12937170) |
MGI TreeGrafter Ensembl |
PMID:12937170 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137
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ATRIP |
ATR interacting protein |
involved_in |
IEA |
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InterPro |
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GO_REF:0000002 |
NCBI chr22:9,849,439...9,869,654
Ensembl chr22:9,849,570...9,869,553
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CDC5L |
cell division cycle 5 like |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:27,727,185...27,785,233
Ensembl chr17:27,722,819...27,785,268
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CHEK1 |
checkpoint kinase 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:10859164) (PMID:12529385) |
InterPro MGI |
PMID:10859164 PMID:12529385 |
GO_REF:0000002 |
NCBI chr 1:116,768,141...116,809,557
Ensembl chr 1:116,767,944...116,801,371
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CHEK2 |
checkpoint kinase 2 |
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ISO |
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RGD |
PMID:10435585 |
RGD:633752 |
NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792
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CLOCK |
clock circadian regulator |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240
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CLSPN |
claspin |
involved_in |
ISO |
(PMID:16963448) |
UniProt |
PMID:16963448 |
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NCBI chr20:97,096,529...97,132,305
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DONSON |
DNA replication fork stabilization factor DONSON |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 2:58,598,341...58,627,279
Ensembl chr 2:58,598,967...58,609,316
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DOT1L |
DOT1 like histone lysine methyltransferase |
involved_in |
IEA |
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UniProt TreeGrafter |
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GO_REF:0000104 GO_REF:0000118 |
NCBI chr 6:1,962,077...2,030,732
Ensembl chr 6:1,962,279...2,026,455
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DTX3L |
deltex E3 ubiquitin ligase 3L |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr22:58,287,331...58,298,519
Ensembl chr22:58,290,764...58,298,376
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E2F1 |
E2F transcription factor 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326
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EIF2AK4 |
eukaryotic translation initiation factor 2 alpha kinase 4 |
involved_in |
IEA |
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InterPro |
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GO_REF:0000002 |
NCBI chr26:42,966,095...43,072,083
Ensembl chr26:42,962,447...43,072,001
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GNB1L |
G protein subunit beta 1 like |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr19:5,889,395...5,959,515
Ensembl chr19:5,890,567...5,959,510
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H2AFX |
histone H2AX |
NOT|acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:11934988) |
MGI Ensembl |
PMID:11934988 |
GO_REF:0000107 |
NCBI chr 1:110,466,692...110,468,776
Ensembl chr 1:110,467,775...110,468,206
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HINFP |
histone H4 transcription factor |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:110,495,188...110,509,855
Ensembl chr 1:110,500,566...110,510,222
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HUS1 |
HUS1 checkpoint clamp component |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:12529385) |
Ensembl MGI InterPro |
PMID:12529385 |
GO_REF:0000002 GO_REF:0000107 |
NCBI chr21:10,826,799...10,841,579
Ensembl chr21:10,826,846...10,841,382
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INTS7 |
integrator complex subunit 7 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr25:17,485,353...17,573,178
Ensembl chr25:17,485,316...17,574,144
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LOC103215829 |
DNA excision repair protein ERCC-6 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 9:42,288,702...42,370,045
Ensembl chr 9:42,288,825...42,373,906
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LYN |
LYN proto-oncogene, Src family tyrosine kinase |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959
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MAP3K20 |
mitogen-activated protein kinase kinase kinase 20 |
involved_in |
ISO |
(PMID:11836244) |
UniProt |
PMID:11836244 |
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NCBI chr10:58,573,303...58,764,759
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MAPK14 |
mitogen-activated protein kinase 14 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:12937170) |
Ensembl MGI |
PMID:12937170 |
GO_REF:0000107 |
NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138
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NBN |
nibrin |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:12529385) |
MGI Ensembl |
PMID:12529385 |
GO_REF:0000107 |
NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028
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PARP9 |
poly(ADP-ribose) polymerase family member 9 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr22:58,297,526...58,336,243
Ensembl chr22:58,298,046...58,337,124
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PRPF19 |
pre-mRNA processing factor 19 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:12,942,238...12,958,853
Ensembl chr 1:12,942,213...12,959,947
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PTPN11 |
protein tyrosine phosphatase non-receptor type 11 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:12937170) |
Ensembl MGI |
PMID:12937170 |
GO_REF:0000107 |
NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637
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RAD1 |
RAD1 checkpoint DNA exonuclease |
involved_in |
IEA |
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Ensembl TreeGrafter InterPro |
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GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 |
NCBI chr 4:33,800,279...33,807,986
Ensembl chr 4:33,801,230...33,807,457
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RAD17 |
RAD17 checkpoint clamp loader component |
involved_in |
IEA |
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InterPro TreeGrafter |
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GO_REF:0000002 GO_REF:0000118 |
NCBI chr 4:65,456,174...65,501,665
Ensembl chr 4:65,457,763...65,501,157
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RAD9A |
RAD9 checkpoint clamp component A |
involved_in |
IEA |
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InterPro Ensembl |
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GO_REF:0000002 GO_REF:0000107 |
NCBI chr 1:6,865,990...6,945,179
Ensembl chr 1:6,866,840...6,941,486
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RAD9B |
RAD9 checkpoint clamp component B |
involved_in |
IEA |
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InterPro |
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GO_REF:0000002 |
NCBI chr11:105,738,247...105,772,539
Ensembl chr11:105,738,867...105,772,002
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RHNO1 |
RAD9-HUS1-RAD1 interacting nuclear orphan 1 |
involved_in |
IEA |
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Ensembl TreeGrafter InterPro |
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GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 |
NCBI chr11:2,941,055...2,955,421
Ensembl chr11:2,941,001...2,955,438
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RPA4 |
replication protein A4 |
involved_in |
ISO |
(PMID:19942684) |
UniProt |
PMID:19942684 |
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NCBI chr X:85,323,910...85,325,997
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SMG1 |
SMG1 nonsense mediated mRNA decay associated PI3K related kinase |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr 5:17,103,482...17,217,554
Ensembl chr 5:17,116,231...17,217,488
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STK38 |
serine/threonine kinase 38 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:35,587,246...35,641,555
Ensembl chr17:35,587,256...35,642,279
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TIPIN |
TIMELESS interacting protein |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:17141802) |
MGI Ensembl |
PMID:17141802 |
GO_REF:0000107 |
NCBI chr26:17,194,859...17,214,671
Ensembl chr26:17,198,734...17,214,810
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TIPRL |
TOR signaling pathway regulator |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr25:60,842,563...60,869,380
Ensembl chr25:60,841,783...60,869,258
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TOPBP1 |
DNA topoisomerase II binding protein 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr15:56,679,333...56,740,773
Ensembl chr15:56,679,426...56,741,566
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TP53BP1 |
tumor protein p53 binding protein 1 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr26:39,489,925...39,595,096
Ensembl chr26:39,508,600...39,594,927
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TREX1 |
three prime repair exonuclease 1 |
acts_upstream_of_or_within |
ISO |
(PMID:18045533) |
MGI |
PMID:18045533 |
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NCBI chr22:9,869,502...9,871,659
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UFL1 |
UFM1 specific ligase 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr13:77,357,239...77,387,385
Ensembl chr13:77,357,141...77,387,367
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USP28 |
ubiquitin specific peptidase 28 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr 1:105,175,116...105,257,163
Ensembl chr 1:105,175,067...105,257,102
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CASP2 |
caspase 2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr21:112,172,614...112,189,574
Ensembl chr21:112,172,733...112,188,744
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CDKN1A |
cyclin dependent kinase inhibitor 1A |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342
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CRADD |
CASP2 and RIPK1 domain containing adaptor with death domain |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr11:89,066,952...89,246,177
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E2F7 |
E2F transcription factor 7 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr11:72,598,220...72,642,366
Ensembl chr11:72,599,353...72,641,420
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MDM2 |
MDM2 proto-oncogene |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890
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MUC1 |
mucin 1, cell surface associated |
involved_in |
ISO |
(PMID:15710329) |
BHF-UCL |
PMID:15710329 |
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NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962
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PCBP4 |
poly(rC) binding protein 4 |
involved_in |
ISO |
(PMID:10891498) |
UniProt |
PMID:10891498 |
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NCBI chr22:13,326,069...13,336,474
Ensembl chr22:13,325,551...13,329,903
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PIDD1 |
p53-induced death domain protein 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:602,594...609,388
Ensembl chr 1:602,721...607,893
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PML |
PML nuclear body scaffold |
involved_in |
ISO |
(PMID:15626733) |
UniProt |
PMID:15626733 |
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NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931
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PPP2R5C |
protein phosphatase 2 regulatory subunit B'gamma |
involved_in |
ISO |
(PMID:17245430) |
UniProt |
PMID:17245430 |
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NCBI chr24:79,703,316...79,875,379
Ensembl chr24:79,703,312...79,875,389
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PRAP1 |
proline rich acidic protein 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr26:53,195,600...53,201,846
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RBM38 |
RNA binding motif protein 38 |
involved_in |
ISO |
(PMID:17050675) |
UniProt |
PMID:17050675 |
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NCBI chr 2:6,709,975...6,727,534
Ensembl chr 2:6,711,458...6,727,353
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RPL26 |
ribosomal protein L26 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr16:7,733,652...7,740,384
Ensembl chr16:7,732,921...7,740,325
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TP53 |
tumor protein p53 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:16107883) |
Ensembl MGI |
PMID:16107883 |
GO_REF:0000107 |
NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
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CDC7 |
cell division cycle 7 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr20:41,714,250...41,739,159
Ensembl chr20:41,715,572...41,739,138
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CHEK2 |
checkpoint kinase 2 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792
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LOC103226086 |
cell division cycle 7-related protein kinase-like |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr21:9,494,995...9,496,895
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ZNF830 |
zinc finger protein 830 |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:23213458) |
MGI Ensembl TreeGrafter |
PMID:23213458 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr16:28,468,548...28,470,150
Ensembl chr16:28,468,616...28,469,734
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CCND1 |
cyclin D1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357
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DGKZ |
diacylglycerol kinase zeta |
involved_in |
ISO |
(PMID:16286473) |
UniProt |
PMID:16286473 |
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NCBI chr 1:18,949,360...18,997,957
Ensembl chr 1:18,948,425...18,982,354
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FBXO31 |
F-box protein 31 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:72,696,868...72,752,480
Ensembl chr 5:72,701,136...72,752,989
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GIGYF2 |
GRB10 interacting GYF protein 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19744960) |
Ensembl MGI |
PMID:19744960 |
GO_REF:0000107 |
NCBI chr10:118,720,668...118,883,299
Ensembl chr10:118,720,690...118,874,162
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PRKDC |
protein kinase, DNA-activated, catalytic subunit |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541
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RFWD3 |
ring finger and WD repeat domain 3 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:53,045,408...53,092,214
Ensembl chr 5:53,045,465...53,092,494
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RPA2 |
replication protein A2 |
involved_in |
ISO |
(PMID:21731742) |
UniProt |
PMID:21731742 |
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NCBI chr20:104,882,739...104,904,612
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RPA2 |
replication protein A2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
Ensembl chr20:104,883,027...104,904,951
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RPS27L |
ribosomal protein S27 like |
involved_in |
ISO |
(PMID:18056458) |
UniProt |
PMID:18056458 |
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NCBI chr26:20,385,684...20,389,351
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SDE2 |
SDE2 telomere maintenance homolog |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr25:3,779,561...3,793,496
Ensembl chr25:3,779,560...3,795,893
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TP53 |
tumor protein p53 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:16107883) |
Ensembl MGI |
PMID:16107883 |
GO_REF:0000107 |
NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
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TREX1 |
three prime repair exonuclease 1 |
acts_upstream_of_or_within |
ISO |
(PMID:23993650) (PMID:18045533) |
MGI |
PMID:18045533 PMID:23993650 |
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NCBI chr22:9,869,502...9,871,659
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WAC |
WW domain containing adaptor with coiled-coil |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 9:28,131,774...28,222,501
Ensembl chr 9:28,131,769...28,219,134
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ABRAXAS1 |
abraxas 1, BRCA1 A complex subunit |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 7:31,852,411...31,875,968
Ensembl chr 7:31,853,490...31,875,189
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ATM |
ATM serine/threonine kinase |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520
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BABAM1 |
BRISC and BRCA1 A complex member 1 |
involved_in |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chr 6:15,775,344...15,786,715
Ensembl chr 6:15,775,229...15,786,822
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BABAM2 |
BRISC and BRCA1 A complex member 2 |
involved_in |
IEA |
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Ensembl UniProt |
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GO_REF:0000104 GO_REF:0000107 |
NCBI chr14:79,277,238...79,732,996
Ensembl chr14:79,289,043...79,732,891
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BLM |
BLM RecQ like helicase |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254
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BRCA1 |
BRCA1 DNA repair associated |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr16:63,162,827...63,243,928
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BRCC3 |
BRCA1/BRCA2-containing complex subunit 3 |
involved_in |
IEA |
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UniProt Ensembl |
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GO_REF:0000104 GO_REF:0000107 |
NCBI chr X:129,358,759...129,406,293
Ensembl chr X:129,358,862...129,403,352
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BRSK1 |
BR serine/threonine kinase 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 6:47,888,813...47,915,019
Ensembl chr 6:47,888,920...47,917,920
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CDC14B |
cell division cycle 14B |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr12:106,520,152...106,645,468
Ensembl chr12:106,572,015...106,633,316
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CDK1 |
cyclin dependent kinase 1 |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:12937170) |
MGI TreeGrafter |
PMID:12937170 |
GO_REF:0000118 |
NCBI chr 9:70,475,736...70,492,947
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CDK5RAP3 |
CDK5 regulatory subunit associated protein 3 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr16:68,367,591...68,382,000
Ensembl chr16:68,370,483...68,382,022
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CDKN1A |
cyclin dependent kinase inhibitor 1A |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342
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CHEK1 |
checkpoint kinase 1 |
involved_in |
ISO |
(PMID:20932473) |
UniProt |
PMID:20932473 |
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NCBI chr 1:116,768,141...116,809,557
Ensembl chr 1:116,767,944...116,801,371
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CLSPN |
claspin |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr20:97,096,529...97,132,305
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CREB3L1 |
cAMP responsive element binding protein 3 like 1 |
involved_in |
ISO |
(PMID:37178686) |
UniProt |
PMID:37178686 |
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NCBI chr 1:19,009,169...19,054,841
Ensembl chr 1:19,009,035...19,054,804
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G |
CUNH10orf90 |
chromosome unknown C10orf90 homolog |
involved_in |
ISO |
(PMID:20154723) |
UniProt |
PMID:20154723 |
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NCBI chr 9:119,049,797...119,290,121
Ensembl chr 9:119,050,676...119,136,762
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DONSON |
DNA replication fork stabilization factor DONSON |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 2:58,598,341...58,627,279
Ensembl chr 2:58,598,967...58,609,316
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DTL |
denticleless E3 ubiquitin protein ligase homolog |
involved_in |
IEA |
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TreeGrafter Ensembl |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chr25:17,418,078...17,485,320
Ensembl chr25:17,418,090...17,485,164
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FOXN3 |
forkhead box N3 |
involved_in |
ISO |
(PMID:9154802) |
UniProt |
PMID:9154802 |
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NCBI chr24:66,832,760...67,103,637
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G |
FOXN3 |
forkhead box N3 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
Ensembl chr24:66,834,410...67,103,656
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FOXO4 |
forkhead box O4 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:12048180) |
Ensembl MGI |
PMID:12048180 |
GO_REF:0000107 |
NCBI chr X:60,893,711...60,901,134
Ensembl chr X:60,893,526...60,902,844
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G |
FZR1 |
fizzy and cell division cycle 20 related 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 6:3,272,247...3,300,370
Ensembl chr 6:3,288,407...3,298,464
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IER3 |
immediate early response 3 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:20467439) |
Ensembl MGI |
PMID:20467439 |
GO_REF:0000107 |
NCBI chr17:41,712,539...41,713,895
Ensembl chr17:41,712,528...41,714,126
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G |
LOC103221857 |
E3 ubiquitin-protein ligase TRIM39 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:42,142,185...42,159,256
Ensembl chr17:42,142,073...42,158,764
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G |
LOC103244593 |
cyclin-dependent kinase 1-like |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr23:40,070,145...40,071,558
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LOC103244924 |
cyclin-G1 |
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ISO |
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RGD |
PMID:9464250 |
RGD:2316029 |
NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711
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G |
MBD4 |
methyl-CpG binding domain 4, DNA glycosylase |
acts_upstream_of_or_within |
ISO |
(PMID:14614141) |
MGI |
PMID:14614141 |
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NCBI chr22:51,616,840...51,626,232
Ensembl chr22:51,616,803...51,626,224
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G |
MBTPS1 |
membrane bound transcription factor peptidase, site 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:69,464,064...69,527,588
Ensembl chr 5:69,463,920...69,527,541
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G |
MBTPS2 |
membrane bound transcription factor peptidase, site 2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr X:20,319,731...20,364,603
Ensembl chr X:20,319,807...20,361,847
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G |
MRE11 |
MRE11 homolog, double strand break repair nuclease |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:14690604) |
MGI Ensembl TreeGrafter |
PMID:14690604 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr 1:85,615,448...85,694,247
Ensembl chr 1:85,610,819...85,694,269
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G |
MRNIP |
MRN complex interacting protein |
involved_in |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chr23:81,571,083...81,590,906
Ensembl chr23:81,571,199...81,590,815
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G |
NBN |
nibrin |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:18614044) |
Ensembl TreeGrafter MGI InterPro |
PMID:18614044 |
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 |
NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028
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G |
NOP53 |
NOP53 ribosome biogenesis factor |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 6:41,058,199...41,070,220
Ensembl chr 6:41,057,906...41,071,202
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G |
PLK1 |
polo like kinase 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718
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G |
RINT1 |
RAD50 interactor 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr21:74,454,916...74,491,057
Ensembl chr21:74,454,947...74,490,768
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G |
SYF2 |
SYF2 pre-mRNA splicing factor |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:22448250) |
Ensembl MGI |
PMID:22448250 |
GO_REF:0000107 |
NCBI chr20:107,468,855...107,478,822
Ensembl chr20:107,468,940...107,479,036
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G |
TAOK1 |
TAO kinase 1 |
involved_in |
ISO |
(PMID:17396146) |
UniProt |
PMID:17396146 |
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NCBI chr16:23,145,629...23,291,694
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G |
TAOK1 |
TAO kinase 1 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
Ensembl chr16:23,145,809...23,282,784
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G |
TAOK2 |
TAO kinase 2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:26,669,687...26,688,418
Ensembl chr 5:26,669,702...26,688,389
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G |
TAOK3 |
TAO kinase 3 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr11:113,485,871...113,717,213
Ensembl chr11:113,484,330...113,704,271
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G |
TICRR |
TOPBP1 interacting checkpoint and replication regulator |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr29:8,117,198...8,171,956
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G |
TOPBP1 |
DNA topoisomerase II binding protein 1 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr15:56,679,333...56,740,773
Ensembl chr15:56,679,426...56,741,566
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G |
UIMC1 |
ubiquitin interaction motif containing 1 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr23:78,912,434...79,010,695
Ensembl chr23:78,911,234...79,010,264
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G |
ATF2 |
activating transcription factor 2 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr10:60,644,623...60,734,465
Ensembl chr10:60,644,635...60,734,475
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G |
CHEK2 |
checkpoint kinase 2 |
involved_in |
ISO |
(PMID:11298456) |
UniProt |
PMID:11298456 |
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NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792
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G |
EME1 |
essential meiotic structure-specific endonuclease 1 |
involved_in |
IEA |
|
TreeGrafter |
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GO_REF:0000118 |
NCBI chr16:42,949,059...42,957,323
Ensembl chr16:42,949,570...42,955,312
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G |
EME2 |
essential meiotic structure-specific endonuclease subunit 2 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr 5:1,682,232...1,685,863
Ensembl chr 5:1,682,249...1,685,260
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G |
FANCD2 |
FA complementation group D2 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr22:46,072,797...46,141,107
Ensembl chr22:46,072,761...46,140,713
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G |
HUS1 |
HUS1 checkpoint clamp component |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr21:10,826,799...10,841,579
Ensembl chr21:10,826,846...10,841,382
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G |
LOC103243152 |
crossover junction endonuclease MUS81 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr16:53,418,865...53,421,128
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G |
MRE11 |
MRE11 homolog, double strand break repair nuclease |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:14690604), (PMID:18614044) |
MGI TreeGrafter Ensembl |
PMID:14690604 PMID:18614044 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr 1:85,615,448...85,694,247
Ensembl chr 1:85,610,819...85,694,269
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G |
MSH2 |
mutS homolog 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15533840) |
Ensembl MGI |
PMID:15533840 |
GO_REF:0000107 |
NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819
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G |
MUS81 |
MUS81 structure-specific endonuclease subunit |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr 1:8,410,571...8,411,793
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G |
NEK11 |
NIMA related kinase 11 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr15:58,884,879...59,178,575
Ensembl chr15:58,884,771...59,175,470
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G |
RAD17 |
RAD17 checkpoint clamp loader component |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr 4:65,456,174...65,501,665
Ensembl chr 4:65,457,763...65,501,157
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G |
RAD9A |
RAD9 checkpoint clamp component A |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:9766521) |
Ensembl TreeGrafter MGI |
PMID:9766521 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr 1:6,865,990...6,945,179
Ensembl chr 1:6,866,840...6,941,486
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G |
RAD9B |
RAD9 checkpoint clamp component B |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr11:105,738,247...105,772,539
Ensembl chr11:105,738,867...105,772,002
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G |
TIPIN |
TIMELESS interacting protein |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr26:17,194,859...17,214,671
Ensembl chr26:17,198,734...17,214,810
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G |
XPC |
XPC complex subunit, DNA damage recognition and repair factor |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15533840) |
Ensembl MGI |
PMID:15533840 |
GO_REF:0000107 |
NCBI chr22:50,088,019...50,121,584
Ensembl chr22:50,085,353...50,121,542
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G |
BRD4 |
bromodomain containing 4 |
involved_in |
ISO |
(PMID:23728299) |
UniProt |
PMID:23728299 |
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NCBI chr 6:13,836,332...13,883,459
Ensembl chr 6:13,836,324...13,873,877
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G |
CHEK2 |
checkpoint kinase 2 |
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ISO |
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RGD |
PMID:20637979 |
RGD:10401658 |
NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792
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G |
PPP1R10 |
protein phosphatase 1 regulatory subunit 10 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr17:41,839,504...41,857,228
Ensembl chr17:41,839,833...41,858,470
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G |
CCAR2 |
cell cycle and apoptosis regulator 2 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr 8:20,685,482...20,700,424
Ensembl chr 8:20,686,504...20,699,707
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G |
TTI1 |
TELO2 interacting protein 1 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr 2:25,717,089...25,768,128
Ensembl chr 2:25,717,118...25,768,610
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G |
MAP3K20 |
mitogen-activated protein kinase kinase kinase 20 |
involved_in |
ISO |
(PMID:15342622) |
UniProt |
PMID:15342622 |
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NCBI chr10:58,573,303...58,764,759
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G |
CRY1 |
cryptochrome circadian regulator 1 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr11:102,200,822...102,306,165
Ensembl chr11:102,204,224...102,306,182
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G |
CUL4A |
cullin 4A |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19481525) |
Ensembl MGI |
PMID:19481525 |
GO_REF:0000107 |
NCBI chr 3:91,211,238...91,267,236
Ensembl chr 3:91,212,193...91,268,838
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G |
ETAA1 |
ETAA1 activator of ATR kinase |
involved_in |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chr14:39,658,974...39,673,093
Ensembl chr14:39,659,873...39,673,259
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G |
FBXO4 |
F-box protein 4 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:21911473) |
Ensembl MGI |
PMID:21911473 |
GO_REF:0000107 |
NCBI chr 4:40,682,063...40,698,364
Ensembl chr 4:40,682,333...40,698,370
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G |
FEM1B |
fem-1 homolog B |
involved_in |
ISO |
(PMID:19330022) |
UniProt |
PMID:19330022 |
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NCBI chr26:15,183,965...15,201,394
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G |
NEK1 |
NIMA related kinase 1 |
involved_in |
ISO |
(PMID:18843199) |
CACAO |
PMID:18843199 |
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NCBI chr 7:115,621,917...115,819,349
Ensembl chr 7:115,621,916...115,819,291
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G |
RFWD3 |
ring finger and WD repeat domain 3 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr 5:53,045,408...53,092,214
Ensembl chr 5:53,045,465...53,092,494
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G |
RNASEH2B |
ribonuclease H2 subunit B |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:22802351) |
MGI Ensembl |
PMID:22802351 |
GO_REF:0000107 |
NCBI chr 3:28,791,490...28,856,542
Ensembl chr 3:28,791,748...28,841,733
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G |
RPA2 |
replication protein A2 |
involved_in |
ISO |
(PMID:21504906) |
UniProt |
PMID:21504906 |
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NCBI chr20:104,882,739...104,904,612
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G |
RPA2 |
replication protein A2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
Ensembl chr20:104,883,027...104,904,951
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G |
WDR76 |
WD repeat domain 76 |
involved_in |
IEA |
|
TreeGrafter |
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GO_REF:0000118 |
NCBI chr26:39,178,407...39,222,005
Ensembl chr26:39,176,535...39,223,993
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Term paths to the root
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