PCBP4 (poly(rC) binding protein 4) - Rat Genome Database

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Gene: PCBP4 (poly(rC) binding protein 4) Chlorocebus sabaeus
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Symbol: PCBP4
Name: poly(rC) binding protein 4
RGD ID: 18635002
Description: ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA binding (inferred); nucleic acid binding (inferred); INVOLVED IN DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (ortholog); PARTICIPATES IN iron homeostasis pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly(rC)-binding protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,326,069 - 13,336,474 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,325,551 - 13,329,903 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,570,710 - 153,609,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PCBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,326,069 - 13,336,474 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,325,551 - 13,329,903 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,570,710 - 153,609,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PCBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,957,454 - 51,967,466 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,957,454 - 51,974,016 (-)EnsemblGRCh38hg38GRCh38
GRCh37351,991,470 - 52,001,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,966,514 - 51,976,509 (-)NCBINCBI36Build 36hg18NCBI36
Build 34351,966,513 - 51,971,948NCBI
Celera351,970,297 - 51,980,309 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,054,808 - 52,064,820 (-)NCBIHuRef
CHM1_1351,944,157 - 51,954,169 (-)NCBICHM1_1
T2T-CHM13v2.0351,990,373 - 52,000,385 (-)NCBIT2T-CHM13v2.0
Pcbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,330,181 - 106,341,211 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,330,490 - 106,341,211 (+)EnsemblGRCm39 Ensembl
GRCm389106,452,982 - 106,464,012 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,453,291 - 106,464,012 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,356,188 - 106,366,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,311,991 - 106,322,108 (+)NCBIMGSCv36mm8
Celera9106,080,920 - 106,090,913 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.54NCBI
Pcbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,971,751 - 115,981,987 (+)NCBIGRCr8
mRatBN7.28107,092,688 - 107,103,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,093,013 - 107,103,276 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,716,011 - 112,726,243 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,915,187 - 110,925,419 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,757,969 - 108,768,201 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,154,848 - 115,165,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,155,470 - 115,165,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,518,974 - 114,529,993 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,597,539 - 111,607,775 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,617,020 - 111,627,230 (+)NCBI
Celera8106,404,965 - 106,415,187 (+)NCBICelera
Cytogenetic Map8q32NCBI
Pcbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,603,975 - 3,614,290 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,604,720 - 3,615,112 (-)NCBIChiLan1.0ChiLan1.0
PCBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,951,805 - 51,961,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,956,571 - 51,966,603 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,898,857 - 51,908,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,127,448 - 53,137,292 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,127,448 - 53,137,293 (-)Ensemblpanpan1.1panPan2
PCBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,748,854 - 37,759,072 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,748,938 - 37,759,073 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,730,280 - 37,740,519 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,099,394 - 38,109,634 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2038,099,389 - 38,109,631 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,462,996 - 37,473,239 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,871,760 - 37,881,997 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,156,623 - 38,166,864 (+)NCBIUU_Cfam_GSD_1.0
Pcbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,543,674 - 66,547,936 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,300,712 - 3,308,288 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,304,171 - 3,308,422 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,090,020 - 34,099,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,090,015 - 34,099,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,286,561 - 37,296,491 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pcbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,775,805 - 5,788,195 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,776,777 - 5,786,782 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 60
Low 20
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000012009   ⟹   ENSCSAP00000010062
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2213,325,551 - 13,329,903 (-)Ensembl
RefSeq Acc Id: XM_007984435   ⟹   XP_007982626
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12213,326,069 - 13,336,473 (-)NCBI
Vero_WHO_p1.0NW_023666041153,570,710 - 153,609,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007984437   ⟹   XP_007982628
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12213,326,069 - 13,331,726 (-)NCBI
Vero_WHO_p1.0NW_023666041153,600,487 - 153,609,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007984438   ⟹   XP_007982629
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12213,326,167 - 13,336,473 (-)NCBI
Vero_WHO_p1.0NW_023666041153,570,710 - 153,609,107 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038003856   ⟹   XP_037859784
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041153,603,766 - 153,609,107 (+)NCBI
RefSeq Acc Id: XM_038003857   ⟹   XP_037859785
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041153,603,766 - 153,609,107 (+)NCBI
RefSeq Acc Id: XM_038003859   ⟹   XP_037859787
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041153,598,626 - 153,609,107 (+)NCBI
RefSeq Acc Id: XM_038003860   ⟹   XP_037859788
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041153,603,767 - 153,609,107 (+)NCBI
RefSeq Acc Id: XP_007982626   ⟸   XM_007984435
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982628   ⟸   XM_007984437
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982629   ⟸   XM_007984438
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000010062   ⟸   ENSCSAT00000012009
RefSeq Acc Id: XP_037859787   ⟸   XM_038003859
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859784   ⟸   XM_038003856
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037859785   ⟸   XM_038003857
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859788   ⟸   XM_038003860
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013913 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012009.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
InterPro KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
KEGG Report csab:103227706 UniProtKB/TrEMBL
NCBI Gene PCBP4 ENTREZGENE
PANTHER KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/TrEMBL
  PTHR10288:SF166 UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
SMART SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt A0A0D9RN73 ENTREZGENE, UniProtKB/TrEMBL