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ONTOLOGY REPORT - ANNOTATIONS


Term:signal transduction in response to DNA damage
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Accession:GO:0042770 term browser browse the term
Definition:A cascade of processes induced by the detection of DNA damage within a cell.
Synonyms:exact_synonym: DNA damage response, signal transduction;   response to DNA damage stimulus by intracellular signaling cascade



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signal transduction in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:15657060), (PMID:9037071) RGD PMID:9037071 PMID:15657060 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:15657060) RGD PMID:15657060 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cep63 centrosomal protein 63 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177
JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO (MGI:3032464|PMID:14744935)
(PMID:14744935)
RGD PMID:14744935 MGI:3032464 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in IEA
ISO
GO_REF:0000107
(PMID:20160708)
Ensembl
RGD
PMID:20160708 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO (PMID:20160708) RGD PMID:20160708 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO (PMID:20160708) RGD PMID:20160708 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2679752|PMID:12937170)
RGD PMID:12937170 PMID:21873635 MGI:2679752, RGD:13792537 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2679752|PMID:12937170)
(PMID:14657349)
RGD PMID:12937170 PMID:14657349 PMID:21873635 MGI:2679752, RGD:13792537 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atrip ATR interacting protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:109,708,440...109,722,511
Ensembl chr 8:109,708,440...109,722,477
JBrowse link
G Cdc5l cell division cycle 5-like involved_in ISS
ISO
GO_REF:0000024
(PMID:24332808)
UniProt
RGD
PMID:24332808 GO_REF:0000024 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
JBrowse link
G Cep63 centrosomal protein 63 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177
JBrowse link
G Chek1 checkpoint kinase 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:16963448), (PMID:19716789)
MGI:1926528 (MGI:1860049|PMID:10859164), (MGI:2449744|PMID:12529385)
GO_REF:0000024
RGD
UniProt
PMID:10859164 PMID:12529385 PMID:16963448 PMID:19716789 GO_REF:0000024 MGI:1860049 MGI:2449744 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:10435585 RGD:633752 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Clock clock circadian regulator involved_in ISO
IEA
(PMID:21659603)
GO_REF:0000107
RGD
Ensembl
PMID:21659603 GO_REF:0000107 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Clspn claspin involved_in ISO (PMID:16963448) RGD PMID:16963448 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475
JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:12717439)
UniProt
RGD
PMID:12717439 GO_REF:0000024 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G H2ax H2A.X variant histone involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:17974976)
MGI:2156048 (MGI:2179182|PMID:11934988)
RGD PMID:11934988 PMID:17974976 MGI:2179182 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hinfp histone H4 transcription factor involved_in ISO (PMID:17974976) RGD PMID:17974976 NCBI chr 8:44,634,333...44,644,288
Ensembl chr 8:44,634,333...44,641,000
JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in
acts_upstream_of_or_within
ISO (PMID:21659603)
MGI:1927769 (MGI:2449744|PMID:12529385)
RGD PMID:12529385 PMID:21659603 MGI:2449744 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2679752|PMID:12937170)
Ensembl
RGD
PMID:12937170 GO_REF:0000107 MGI:2679752 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Nbn nibrin acts_upstream_of_or_within ISO (PMID:12529385) RGD PMID:12529385 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISS
ISO
GO_REF:0000024
(PMID:24332808)
UniProt
RGD
PMID:24332808 GO_REF:0000024 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:2176524 (MGI:2679752|PMID:12937170) RGD PMID:12937170 MGI:2679752 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO
IBA
(PMID:21659603)
PMID:21873635
RGD PMID:21659603 PMID:21873635 RGD:13792537 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in ISO
IBA
(PMID:21659603)
PMID:21873635
RGD PMID:21659603 PMID:21873635 RGD:13792537 NCBI chr 4:161,634,047...161,639,437
Ensembl chr 4:161,634,048...161,639,371
JBrowse link
G Tipin timeless interacting protein acts_upstream_of_or_within ISO (MGI:3706226|PMID:17141802) RGD PMID:17141802 MGI:3706226 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) RGD PMID:18045533 MGI:3818783 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:18662541)
UniProt
RGD
PMID:18662541 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229
JBrowse link
DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:28294157), (PMID:29229990) RGD PMID:28294157 PMID:29229990 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Atrx ATRX, chromatin remodeler involved_in ISS
ISO
GO_REF:0000024
(MGI:5568153|PMID:24651726)
UniProt
RGD
PMID:24651726 GO_REF:0000024 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:5448499|PMID:22385964)
UniProt
RGD
PMID:22385964 GO_REF:0000024 MGI:5448499 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G E2f7 E2F transcription factor 7 involved_in ISO
IEA
ISS
(PMID:22802528)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22802528 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO (MGI:3057054|PMID:15383658) RGD PMID:15383658 MGI:3057054 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:14660608) RGD PMID:14660608 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226
JBrowse link
G Mif macrophage migration inhibitory factor acts_upstream_of_or_within ISO MGI:2673280 (MGI:2670239|PMID:12878730) RGD PMID:12878730 MGI:2670239 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:16507995) RGD PMID:16507995 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO
IEA
(PMID:9766676)
GO_REF:0000107
RGD
Ensembl
PMID:9766676 GO_REF:0000107 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:15456759), (PMID:17690115) RGD PMID:15456759 PMID:17690115 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D acts_upstream_of_or_within ISO (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:18692468)
(MGI:3808916|PMID:18692468)
RGD PMID:18692468 MGI:3808916 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:15149599), (PMID:20160708)
MGI:106184|MGI:109337 (MGI:2156961|PMID:11790307), (MGI:3032953|PMID:11884608), (MGI:3603875|PMID:16199867), (MGI:3714678|PMID:17476307)
RGD PMID:11790307 PMID:11884608 PMID:15149599 PMID:16199867 PMID:17476307 More... MGI:2156961 MGI:3032953 MGI:3603875 MGI:3714678 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20096447)
UniProt
RGD
PMID:20096447 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in IBA
ISO
PMID:21873635
(PMID:21726810)
RGD PMID:21726810 PMID:21873635 RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23235459)
UniProt
RGD
PMID:23235459 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO
IEA
(PMID:16213212)
GO_REF:0000107
(MGI:5882892|PMID:16213212)
RGD
Ensembl
PMID:16213212 GO_REF:0000107 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)
RGD PMID:16107883 PMID:16213212 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1930616 (MGI:84760|PMID:8738145)
Ensembl
RGD
PMID:8738145 GO_REF:0000107 MGI:84760 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA
(PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)
RGD
Ensembl
PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:16387653) RGD PMID:16387653 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:14966270)
UniProt
RGD
PMID:14966270 GO_REF:0000024 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381
JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in IBA
ISO
PMID:21873635
(PMID:15042092)
RGD PMID:15042092 PMID:21873635 RGD:13792537 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484
JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:16213212), (PMID:16479015), (PMID:7958916)
(MGI:1354114|PMID:10710310)
RGD PMID:7958916 PMID:10710310 PMID:16213212 PMID:16479015 MGI:1354114 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
DNA damage response, signal transduction resulting in transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17296730)
UniProt
RGD
PMID:17296730 GO_REF:0000024 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
mitotic DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Stk33 serine/threonine kinase 33 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:163,276,176...163,458,580
Ensembl chr 1:163,276,340...163,458,627
JBrowse link
G Zfp830 zinc finger protein 830 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3583779 (MGI:5428139|PMID:23213458)
RGD PMID:23213458 PMID:21873635 MGI:5428139, RGD:13792537 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19412162)
UniProt
RGD
PMID:19412162 GO_REF:0000024 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO UniProtKB:P06400 (PMID:16286473) RGD PMID:16286473 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Fbxo31 F-box protein 31 involved_in ISS
ISO
GO_REF:0000024
(PMID:19412162)
UniProt
RGD
PMID:19412162 GO_REF:0000024 NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO MGI:4126459 (MGI:4366664|PMID:19744960) RGD PMID:19744960 MGI:4366664 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) RGD PMID:20173098 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479
JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in ISO
IEA
(PMID:27906959)
GO_REF:0000107
RGD
Ensembl
PMID:27906959 GO_REF:0000107 NCBI chr13:92,578,843...92,595,142
Ensembl chr13:92,578,874...92,595,140
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:7958916)
(MGI:3589512|PMID:16107883)
RGD PMID:7958916 PMID:16107883 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:3818783|PMID:18045533), (MGI:5562498|PMID:23993650) RGD PMID:18045533 PMID:23993650 MGI:3818783 MGI:5562498 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) RGD PMID:21329877 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,796,281...8,810,625
Ensembl chr14:8,796,266...8,810,622
JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19261746), (PMID:19261748), (PMID:19261749)
UniProt
RGD
PMID:19261746 PMID:19261748 PMID:19261749 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19261748)
UniProt
RGD
PMID:19261748 GO_REF:0000024 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) RGD PMID:11309417 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
(PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107
RGD
Ensembl
PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:17525341), (PMID:19261746), (PMID:19261748)
UniProt
RGD
PMID:17525341 PMID:19261746 PMID:19261748 GO_REF:0000024 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) RGD PMID:15150265 NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365
JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISS PMID:15150265 UniProt PMID:15150265 RGD:8554801 NCBI chr 1:197,035,522...197,088,624
Ensembl chr 1:197,035,633...197,088,092
JBrowse link
G Ccng1 cyclin G1 IMP RGD PMID:9464250 RGD:2316029 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdk1 cyclin-dependent kinase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2679752|PMID:12937170)
RGD PMID:12937170 PMID:21873635 MGI:2679752, RGD:13792537 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO
ISS
(PMID:15790566)
GO_REF:0000024
RGD
UniProt
PMID:15790566 GO_REF:0000024 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) RGD PMID:23213251 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) RGD PMID:20932473 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Clspn claspin involved_in ISO
IBA
(PMID:18662541)
PMID:21873635
RGD PMID:18662541 PMID:21873635 RGD:13792537 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO
IBA
(PMID:17085480)
PMID:21873635
RGD PMID:17085480 PMID:21873635 RGD:13792537 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Foxn3 forkhead box N3 involved_in ISO UniProtKB:P38111 (PMID:9154802) RGD PMID:9154802 NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401
JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (MGI:2183145|PMID:12048180) RGD PMID:12048180 MGI:2183145 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO (PMID:16061642) RGD PMID:16061642 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:5432078|PMID:20467439) RGD PMID:20467439 MGI:5432078 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in ISO (MGI:4455105|PMID:20154723) RGD PMID:20154723 MGI:4455105 NCBI chr 1:189,059,744...189,293,353
Ensembl chr 1:189,059,746...189,293,435
JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase acts_upstream_of_or_within ISO MGI:2684310 (MGI:2682526|PMID:14614141) RGD PMID:14614141 MGI:2682526 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:3027036 (MGI:2683367|PMID:14690604)
PMID:21873635
Ensembl
RGD
PMID:14690604 PMID:21873635 GO_REF:0000107 MGI:2683367, RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO
IBA
(PMID:27568553)
PMID:21873635
RGD PMID:27568553 PMID:21873635 RGD:13792537 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469
JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
ISS
PMID:21873635
MGI:2183796 (MGI:3805397|PMID:18614044)
GO_REF:0000107
GO_REF:0000024
(PMID:11438675)
RGD
Ensembl
UniProt
PMID:11438675 PMID:18614044 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3805397, RGD:13792537 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) RGD PMID:21741933 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:18662541)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18662541 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO (PMID:11096100) RGD PMID:11096100 NCBI chr 4:11,319,416...11,355,773
Ensembl chr 4:11,320,955...11,355,736
JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor acts_upstream_of_or_within ISO MGI:3904866 (MGI:5435138|PMID:22448250) RGD PMID:22448250 MGI:5435138 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
IEA
ISS
(PMID:17396146)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
IEA
ISS
(PMID:17396146)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Taok3 TAO kinase 3 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17396146)
Ensembl
UniProt
RGD
PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244
JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
ISS
(PMID:23213251)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23213251 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799
JBrowse link
mitotic intra-S DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO
ISS
(PMID:15916964)
GO_REF:0000024
RGD
UniProt
PMID:15916964 GO_REF:0000024 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:11298456) RGD PMID:11298456 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:79,586,736...79,595,515
Ensembl chr10:79,586,729...79,595,435
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968
JBrowse link
G Fancd2 FA complementation group D2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:3027036 (MGI:2683367|PMID:14690604), (MGI:3805397|PMID:18614044)
PMID:21873635
Ensembl
RGD
PMID:14690604 PMID:18614044 PMID:21873635 GO_REF:0000107 MGI:2683367 MGI:3805397, RGD:13792537 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103557 (MGI:3512823|PMID:15533840)
Ensembl
RGD
PMID:15533840 GO_REF:0000107 MGI:3512823 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843
JBrowse link
G Nek11 NIMA-related kinase 11 involved_in ISO
IBA
(PMID:15161910)
PMID:21873635
RGD PMID:15161910 PMID:21873635 RGD:13792537 NCBI chr 8:105,767,230...106,026,676
Ensembl chr 8:105,770,548...106,026,676
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:15538388) RGD PMID:15538388 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P26306 (MGI:1289930|PMID:9766521)
RGD PMID:9766521 PMID:21873635 MGI:1289930, RGD:13792537 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372
JBrowse link
G Tipin timeless interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:17102137)
UniProt
RGD
PMID:17102137 GO_REF:0000024 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:101816 (MGI:3512823|PMID:15533840) RGD PMID:15533840 MGI:3512823 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934
JBrowse link
G Ddx39b DExD-box helicase 39B involved_in ISS
ISO
GO_REF:0000024
(PMID:22144908)
UniProt
RGD
PMID:22144908 GO_REF:0000024 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
JBrowse link
G Thoc1 THO complex 1 involved_in ISO (PMID:22144908) RGD PMID:22144908 NCBI chr18:983,606...1,020,379
Ensembl chr18:983,824...1,019,114
JBrowse link
G Thoc5 THO complex 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:22144908)
UniProt
RGD
PMID:22144908 GO_REF:0000024 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)
RGD PMID:17045821 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd74 CD74 molecule involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17045821)
(MGI:3690285|PMID:17045821)
BHF-UCL
RGD
PMID:17045821 PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:4838949|PMID:20167603)
Ensembl
RGD
PMID:20167603 GO_REF:0000107 MGI:4838949 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISO
ISS
(PMID:29295817)
GO_REF:0000024
RGD
UniProt
PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:10360174), (PMID:9529249) RGD PMID:9529249 PMID:10360174 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)
RGD PMID:17045821 MGI:3690285 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:16023600)
UniProt
RGD
PMID:16023600 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097
JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
JBrowse link
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:5433829|PMID:21183956) RGD PMID:21183956 MGI:5433829 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:11672523) RGD PMID:11672523 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (MGI:5050389|PMID:20817677) RGD PMID:20817677 MGI:5050389 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO
IBA
UniProtKB:Q15554 (PMID:23426265)
PMID:21873635
RGD PMID:23426265 PMID:21873635 RGD:13792537 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:20599664) RGD PMID:20599664 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) RGD PMID:9925639 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335) RGD PMID:16269335 MGI:5297787 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19197340)
UniProt
RGD
PMID:19197340 GO_REF:0000024 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)
RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:15251430) RGD PMID:15251430 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO
IEA
(PMID:16213212)
GO_REF:0000107
RGD
Ensembl
PMID:16213212 GO_REF:0000107 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (PMID:17700068) RGD PMID:17700068 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880
JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) RGD PMID:15342622 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Pbk PDZ binding kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5567851|PMID:24489120)
UniProt
RGD
PMID:24489120 GO_REF:0000024 MGI:5567851 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO MGI:3851025 (MGI:3850765|PMID:19481525) RGD PMID:19481525 MGI:3850765 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO
IBA
(PMID:27723717), (PMID:27723720)
PMID:21873635
RGD PMID:27723717 PMID:27723720 PMID:21873635 RGD:13792537 Ensembl chr14:92,299,553...92,314,104 JBrowse link
G Etaa1l1 Ewing tumor-associated antigen 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104
JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO MGI:5301830 (MGI:5299398|PMID:21911473) RGD PMID:21911473 MGI:5299398 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
JBrowse link
G Fem1b fem-1 homolog B involved_in ISS
ISO
GO_REF:0000024
(PMID:19330022)
UniProt
RGD
PMID:19330022 GO_REF:0000024 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
JBrowse link
G Nek1 NIMA-related kinase 1 involved_in ISO (MGI:5619475|PMID:18843199) RGD PMID:18843199 MGI:5619475 NCBI chr16:28,998,229...29,125,426
Ensembl chr16:28,998,231...29,117,723
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:21504906) RGD PMID:21504906 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479
JBrowse link
G Rnaseh2b ribonuclease H2, subunit B acts_upstream_of_or_within ISO MGI:4432164 (MGI:5435090|PMID:22802351) RGD PMID:22802351 MGI:5435090 NCBI chr15:36,541,200...36,592,016
Ensembl chr15:36,541,218...36,584,118
JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS
(PMID:21504906)
GO_REF:0000024
RGD
UniProt
PMID:21504906 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Wdr76 WD repeat domain 76 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840
JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G Kmt5a lysine methyltransferase 5A involved_in ISO
IBA
(PMID:17707234)
PMID:21873635
RGD PMID:17707234 PMID:21873635 RGD:13792537 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO MGI:98834 (MGI:3603875|PMID:16199867) RGD PMID:16199867 MGI:3603875 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G RGD1561318 similar to SET domain-containing protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731
JBrowse link
G Smyd2 SET and MYND domain containing 2 involved_in ISO
ISS
(PMID:17108971)
GO_REF:0000024
RGD
UniProt
PMID:17108971 GO_REF:0000024 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:3789238|PMID:16079796), (MGI:5013521|PMID:21522133) RGD PMID:16079796 PMID:21522133 MGI:3789238 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops3 COP9 signalosome subunit 3 involved_in ISO (PMID:15861129) RGD PMID:15861129 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    signaling 7399
      signal transduction 6838
        intracellular signal transduction 2675
          signal transduction in response to DNA damage 179
            DNA damage checkpoint signaling + 116
            DNA damage response, signal transduction by p53 class mediator + 73
            DNA damage response, signal transduction resulting in transcription + 20
Path 2
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of biological process 12644
        regulation of cellular process 11961
          signal transduction 6838
            intracellular signal transduction 2675
              signal transduction in response to DNA damage 179
                DNA damage checkpoint signaling + 116
                DNA damage response, signal transduction by p53 class mediator + 73
                DNA damage response, signal transduction resulting in transcription + 20
paths to the root