CDK5RAP3 (CDK5 regulatory subunit associated protein 3) - Rat Genome Database

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Gene: CDK5RAP3 (CDK5 regulatory subunit associated protein 3) Chlorocebus sabaeus
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Symbol: CDK5RAP3
Name: CDK5 regulatory subunit associated protein 3
RGD ID: 18672660
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of NF-kappaB transcription factor activity (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDK5 regulatory subunit-associated protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,367,591 - 68,382,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,303 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDK5RAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,367,591 - 68,382,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,303 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CDK5RAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,967,904 - 47,981,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,967,810 - 47,981,781 (+)EnsemblGRCh38hg38GRCh38
GRCh371746,047,894 - 46,059,147 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,403,428 - 43,414,146 (+)NCBINCBI36Build 36hg18NCBI36
Build 341743,403,427 - 43,414,146NCBI
Celera1742,501,248 - 42,511,966 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,416,597 - 41,427,853 (+)NCBIHuRef
CHM1_11746,112,862 - 46,124,122 (+)NCBICHM1_1
T2T-CHM13v2.01748,829,702 - 48,843,580 (+)NCBIT2T-CHM13v2.0
Cdk5rap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,798,251 - 96,807,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,798,252 - 96,807,322 (-)EnsemblGRCm39 Ensembl
GRCm381196,907,425 - 96,916,531 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,907,426 - 96,916,496 (-)EnsemblGRCm38mm10GRCm38
MGSCv371196,769,100 - 96,777,795 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,723,876 - 96,732,571 (-)NCBIMGSCv36mm8
Celera11106,553,602 - 106,563,974 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.16NCBI
Cdk5rap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,390,845 - 82,402,814 (-)NCBIGRCr8
mRatBN7.21081,894,393 - 81,903,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,894,393 - 81,903,590 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1086,842,458 - 86,851,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01086,340,506 - 86,349,660 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,733,108 - 81,742,263 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01084,780,644 - 84,789,800 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,780,608 - 84,789,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,571,933 - 84,581,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1080,656,149 - 80,665,286 (-)NCBICelera
Cytogenetic Map10q31NCBI
Cdk5rap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,120,761 - 13,170,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,160,811 - 13,170,012 (-)NCBIChiLan1.0ChiLan1.0
CDK5RAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,122,187 - 17,134,982 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,087,819 - 19,098,641 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,556,313 - 9,567,099 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,738,144 - 9,748,989 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,738,141 - 9,749,302 (-)Ensemblpanpan1.1panPan2
CDK5RAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,276,660 - 24,286,273 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,276,768 - 24,286,272 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,742,863 - 23,752,452 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,070,151 - 25,079,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,070,173 - 25,079,745 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,840,058 - 23,849,636 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,101,046 - 24,110,629 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,227,612 - 24,237,208 (+)NCBIUU_Cfam_GSD_1.0
Cdk5rap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,719,423 - 23,729,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,345,443 - 13,355,841 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,345,443 - 13,355,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK5RAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,224,263 - 24,234,467 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,224,262 - 24,234,468 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,044,526 - 24,053,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cdk5rap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,594,207 - 4,602,583 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,594,131 - 4,602,435 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDK5RAP3
315 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000581   ⟹   ENSCSAP00000015482
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)Ensembl
RefSeq Acc Id: XM_008012975   ⟹   XP_008011166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,370,832 - 68,382,000 (+)NCBI
Vero_WHO_p1.0NW_02366607739,423,081 - 39,434,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012976   ⟹   XP_008011167
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,371,251 - 68,381,973 (+)NCBI
Vero_WHO_p1.0NW_02366607739,423,481 - 39,434,302 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012978   ⟹   XP_008011169
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,367,591 - 68,382,000 (+)NCBI
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,302 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037993238   ⟹   XP_037849166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,492 - 39,434,302 (+)NCBI
RefSeq Acc Id: XM_037993239   ⟹   XP_037849167
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,175 - 39,434,302 (+)NCBI
RefSeq Acc Id: XM_037993240   ⟹   XP_037849168
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,081 - 39,434,296 (+)NCBI
RefSeq Acc Id: XP_008011169   ⟸   XM_008012978
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008011166   ⟸   XM_008012975
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008011167   ⟸   XM_008012976
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000015482   ⟸   ENSCSAT00000000581
RefSeq Acc Id: XP_037849168   ⟸   XM_037993240
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037849167   ⟸   XM_037993239
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037849166   ⟸   XM_037993238
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002562 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000581.1 UniProtKB/TrEMBL
InterPro CDK5RAP3 UniProtKB/TrEMBL
KEGG Report csab:103243591 UniProtKB/TrEMBL
NCBI Gene CDK5RAP3 ENTREZGENE
PANTHER CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 UniProtKB/TrEMBL
  PTHR14894 UniProtKB/TrEMBL
Pfam DUF773 UniProtKB/TrEMBL
UniProt A0A0D9S3P3 ENTREZGENE, UniProtKB/TrEMBL