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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:breast adenocarcinoma
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Accession:DOID:3458 term browser browse the term
Definition:A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast. (DO)
Synonyms:exact_synonym: Adenocarcinoma of the breast;   Breast adenocarcinoma, somatic;   Mammary adenocarcinoma;   adenocarcinoma of breast
 narrow_synonym: Normal Breast-Like Subtype of Breast Carcinoma;   basal-like breast carcinoma
 broad_synonym: Mixed Lobular and Ductal Breast Carcinoma
 primary_id: RDO:9000715
 xref: EFO:0000281;   EFO:0000304;   EFO:0000592;   EFO:1000382;   EFO:1000402;   NCI:C5214
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
breast adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G BRCA1 BRCA1 DNA repair associated treatment ISO RGD PMID:8589721 RGD:126925966 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494 		JBrowse link
G CAT catalase ISO RGD PMID:25050522 RGD:9226881 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447 		JBrowse link
G CCNE1 cyclin E1 ISO DNA:amplification RGD PMID:18089785 RGD:2289225 NCBI chr 1:121,688,622...121,697,533
Ensembl chr 1:121,688,796...121,697,649 		JBrowse link
G CCNG1 cyclin G1 ISO mRNA, protein:altered expression:mammary (mouse) RGD PMID:11146550 RGD:2315939 NCBI chr 4:47,800,697...47,808,259
Ensembl chr 4:47,801,575...47,808,211 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO mRNA:increased expression:mammary epithelium (rat) RGD PMID:11097088 RGD:7829735 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 no_association ISO DNA:mutation:exons:no mutations found in mutation hotspots in exons 7, 10 or 15 RGD PMID:11466624 RGD:2289868 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:12460918 More... NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G KSR1 kinase suppressor of ras 1 severity ISO RGD PMID:24909178 RGD:127229932 NCBI chr 9:41,981,475...42,136,552
Ensembl chr 9:41,980,734...42,133,653 		JBrowse link
G MUC1 mucin 1, cell surface associated ISO mRNA,protein:increased expression:breast RGD PMID:7678777 RGD:2324855 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690 		JBrowse link
G MXI1 MAX interactor 1, dimerization protein ISO RGD PMID:10849326 RGD:1298988 NCBI chr28:21,584,856...21,655,233
Ensembl chr28:21,584,638...21,652,920 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G RB1CC1 RB1 inducible coiled-coil 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:12068296 NCBI chr29:4,445,668...4,544,223
Ensembl chr29:4,375,785...4,517,168 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:9520460 NCBI chr18:46,878,096...46,898,016
Ensembl chr18:46,878,030...46,898,006 		JBrowse link
G TNF tumor necrosis factor ISO human protein in a rat model RGD PMID:12536235 RGD:14995452 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:1673792 PMID:1686725 PMID:7881428 PMID:8364550 PMID:10713666 More... NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
mammary Paget's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO DNA:amplification RGD PMID:16932067 RGD:2289933 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17773
    disease of cellular proliferation 7264
      cancer 5271
        cell type cancer 3620
          carcinoma 3100
            adenocarcinoma 1647
              breast adenocarcinoma 17
                acinic cell breast carcinoma 0
                breast apocrine carcinoma 0
                breast medullary carcinoma 0
                breast mucinous carcinoma + 0
                breast oncocytic carcinoma 0
                breast secretory carcinoma + 0
                breast signet ring cell adenocarcinoma 0
                breast tubular carcinoma 0
                glycogen-rich carcinoma + 0
                inflammatory breast carcinoma 0
                mammary Paget's disease 1
Path 2
Term Annotations click to browse term
  disease 17773
    Pathological Conditions, Signs and Symptoms 12025
      Signs and Symptoms 9902
        Neurologic Manifestations 9577
          sensory system disease 6598
            skin disease 3758
              breast disease 1253
                Breast Neoplasms 1243
                  breast cancer 699
                    breast carcinoma 284
                      breast adenocarcinoma 17
                        acinic cell breast carcinoma 0
                        breast apocrine carcinoma 0
                        breast medullary carcinoma 0
                        breast mucinous carcinoma + 0
                        breast oncocytic carcinoma 0
                        breast secretory carcinoma + 0
                        breast signet ring cell adenocarcinoma 0
                        breast tubular carcinoma 0
                        glycogen-rich carcinoma + 0
                        inflammatory breast carcinoma 0
                        mammary Paget's disease 1
paths to the root