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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:breast disease
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Accession:DOID:3463 term browser browse the term
Definition:A disease of anatomical entity that is located_in the breast. (DO)
Synonyms:exact_synonym: breast diseases;   endocrine breast disease;   endocrine breast diseases
 xref: EFO:0009483;   ICD10CM:N64.9;   ICD9CM:610-612.99;   MESH:D001941;   MONDO:0002657;   NCI:C26709
For additional species annotation, visit the Alliance of Genome Resources.



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breast disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11462173 NCBI chr11:88,343,647...88,554,543 JBrowse link
17-beta hydroxysteroid dehydrogenase 3 deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col5a1 collagen type V alpha 1 chain ISO ClinVar Annotator: match by term: 17 alpha ketosteroid reductase deficiency of testis ClinVar PMID:25326637 PMID:25741868 PMID:28492532 NCBI chr 3:11,208,429...11,356,715 JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 ISO
ISS
ClinVar Annotator: match by term: HSD17B3-related condition | ClinVar Annotator: match by term: Testosterone 17-beta-dehydrogenase deficiency
OMIM:264300
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
MouseDO
CTD
PMID:598011 PMID:2918056 PMID:3066852 PMID:8075637 PMID:8550739 More... NCBI chr17:1,027,229...1,058,554 JBrowse link
Animal Mammary Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr16:45,755,246...45,821,541 JBrowse link
G Actb actin, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:16,776,664...16,779,634 JBrowse link
G Actg1 actin, gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:106,118,106...106,120,951 JBrowse link
G Actn4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:84,182,783...84,251,867 JBrowse link
G Adcy5 adenylate cyclase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr11:78,976,861...79,123,343 JBrowse link
G Alcam activated leukocyte cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr11:61,804,932...62,005,250 JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 PMID:22248470 NCBI chr 1:227,287,713...227,306,739 JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr 8:78,986,252...79,022,638 JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:120,741,750...120,798,534 JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:9111214 NCBI chr18:26,138,382...26,196,021 JBrowse link
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 4:85,812,784...85,824,964 JBrowse link
G Areg amphiregulin IEP mRNA:increased expression:mammary gland RGD PMID:18421211 RGD:2292665 NCBI chr14:17,256,384...17,265,641 JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 5:144,738,950...144,742,668 JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:77,546,628...77,594,297 JBrowse link
G Brca1 BRCA1, DNA repair associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203372 NCBI chr10:86,917,693...86,978,012 JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:151,435,600...151,535,409 JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr  X:11,572,328...11,915,831 JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:14522882 PMID:16316942 PMID:17173897 NCBI chr 1:209,518,288...209,527,986 JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:17,570,449...17,591,078 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:19787232 RGD:6893387 NCBI chr 8:123,586,100...123,634,178 JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:15922965 RGD:8547789 NCBI chr 3:174,209,113...174,224,592 JBrowse link
G Cdc42 cell division cycle 42 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:154,838,478...154,876,629 JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr19:51,402,178...51,471,572 JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:14522882 NCBI chr 7:64,771,453...64,774,891 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A onset ISO RGD PMID:11103935 RGD:8662404 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:7,820,328...7,882,943 JBrowse link
G Cnn3 calponin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:209,518,948...209,550,107 JBrowse link
G Col5a1 collagen type V alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:11,208,429...11,356,715 JBrowse link
G Comt catechol-O-methyltransferase ISO protein:increased expression:mammary gland, cytoplasm
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18424824 PMID:6337293 RGD:2289734 NCBI chr11:96,072,371...96,091,956 JBrowse link
G Coro1a coronin 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489049 NCBI chr 1:181,295,561...181,300,566 JBrowse link
G Csn2 casein beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:9879772 PMID:16316942 NCBI chr14:20,322,581...20,329,818 JBrowse link
G Csn3 casein kappa ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:20,154,032...20,160,585 JBrowse link
G Dbi diazepam binding inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr13:33,794,231...33,802,632 JBrowse link
G Des desmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:84,299,626...84,307,344 JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:35,979,502...35,983,834 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 8:79,341,554...79,344,784 JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:106,811,769...106,890,961 JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr14:95,378,626...95,551,358 JBrowse link
G Eif5a eukaryotic translation initiation factor 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:55,138,821...55,143,272 JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:160,719,951...160,731,337 JBrowse link
G Epcam epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:12,633,715...12,649,678 JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr13:95,246,079...95,275,852 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603490 PMID:38892447 NCBI chr10:83,907,491...83,931,365 JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15637090 PMID:17173897 PMID:34606849 NCBI chr 1:43,511,685...43,904,454 JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15637090 NCBI chr 6:100,589,553...100,645,240 JBrowse link
G Ezr ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:49,373,033...49,416,573 JBrowse link
G F11r F11 receptor ISO RGD PMID:21695058 RGD:7488916 NCBI chr13:86,406,229...86,429,819 JBrowse link
G Fabp4 fatty acid binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 2:93,488,251...93,492,961 JBrowse link
G Fgf2 fibroblast growth factor 2 ISO RGD PMID:22407271 RGD:8554853 NCBI chr 2:122,164,454...122,218,796 JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 9:80,645,507...80,714,200 JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 1:143,757,389...143,770,430 JBrowse link
G G0s2 G0/G1switch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr13:107,335,036...107,335,948 JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr17:68,643,760...68,666,000 JBrowse link
G Gatm glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:109,658,919...109,675,508 JBrowse link
G Gda guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:218,903,045...218,982,360 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr20:13,074,695...13,104,095 JBrowse link
G Gnai2 G protein subunit alpha i2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:117,167,045...117,187,652 JBrowse link
G Gss glutathione synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:144,047,849...144,078,197 JBrowse link
G H3f3b H3.3 histone B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:101,256,484...101,258,716 JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr10:15,828,291...15,829,138 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:136,253,633...136,260,085 JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8185828 NCBI chr 1:205,712,625...205,729,406 JBrowse link
G Id3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:153,656,253...153,657,860 JBrowse link
G Id4 inhibitor of DNA binding 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14633621 NCBI chr17:16,389,387...16,391,956 JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA:increased expression:mammary gland RGD PMID:18421211 RGD:2292665 NCBI chr 1:197,814,409...197,831,802 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:45,798,872...45,839,501 JBrowse link
G Ins1 insulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21558470 NCBI chr 1:261,186,119...261,186,686 JBrowse link
G Insig1 insulin induced gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 4:8,049,339...8,057,812 JBrowse link
G Kdr kinase insert domain receptor ISO RGD PMID:19888452 RGD:5684399 NCBI chr14:32,572,031...32,615,204 JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:36,782,621...36,863,796 JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr11:77,812,757...77,835,555 JBrowse link
G Krt5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:132,846,132...132,851,861 JBrowse link
G Krt71 keratin 71 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:132,873,532...132,898,975 JBrowse link
G Lgals7 galectin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:84,148,612...84,152,016 JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:42,586,704...42,742,609 JBrowse link
G Lpl lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr16:25,596,205...25,621,928 JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 1:86,185,769...86,201,952 JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:17016428 RGD:7495832 NCBI chr10:95,872,747...95,987,747 JBrowse link
G Mdh2 malate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:20,894,269...20,907,225 JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr20:12,790,919...12,791,784 JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr 8:41,901,225...41,901,304 JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr10:81,283,171...81,283,280 JBrowse link
G Mir10b microRNA 10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr 3:59,628,438...59,628,546 JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir199a2 microRNA 199a-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr13:74,582,954...74,583,063 JBrowse link
G Mir205 microRNA 205 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24447120 NCBI chr13:105,035,878...105,035,985 JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:23714264 RGD:8547831 NCBI chr 3:174,103,474...174,111,434 JBrowse link
G Mpzl1 myelin protein zero-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr13:77,852,467...77,889,305 JBrowse link
G Mrc2 mannose receptor, C type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:90,261,986...90,323,187 JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462
G Ndn necdin, MAGE family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489049 NCBI chr 1:115,849,168...115,850,767 JBrowse link
G Notch4 notch receptor 4 ISO DNA, mRNA:mutation, alternative form RGD PMID:8030284 RGD:2299155 NCBI chr20:4,160,362...4,184,466 JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:28,260,018...28,268,790 JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ameliorates ISO RGD PMID:20802235 RGD:150520014 NCBI chr 1:141,526,192...141,913,575 JBrowse link
G Padi4 peptidyl arginine deiminase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:153,041,351...153,074,412 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr12:15,645,549...15,667,056 JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:44,946,307...44,967,890 JBrowse link
G Pgam1 phosphoglycerate mutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:250,673,152...250,680,762 JBrowse link
G Pgr progesterone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15637090 NCBI chr 8:14,354,398...14,413,271 JBrowse link
G Phb1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr10:81,102,043...81,114,815 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:34,612,946...34,697,660 JBrowse link
G Pkm pyruvate kinase M1/2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:68,949,731...68,975,394 JBrowse link
G Plk2 polo-like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:43,702,536...43,708,305 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11137312 NCBI chr 7:118,712,261...118,780,723 JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr19:23,180,927...23,186,217 JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:6280079 PMID:16316942 NCBI chr17:38,287,355...38,298,234 JBrowse link
G Prlr prolactin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 PMID:17173897 NCBI chr 2:60,861,391...61,051,883 JBrowse link
G Psma4 proteasome 20S subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:64,236,520...64,243,980 JBrowse link
G Psme1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:29,069,012...29,071,888 JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:9,842,574...9,852,332 JBrowse link
G Ptger1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751431 NCBI chr19:24,470,258...24,473,687 JBrowse link
G Ptn pleiotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:66,260,764...66,342,614 JBrowse link
G Ran RAN, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr12:27,674,049...27,678,598 JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:15,857,704...15,940,757 JBrowse link
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:23,113,613...23,361,537 JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008439 NCBI chr 8:117,103,665...117,114,805 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:14522882 PMID:21364977 RGD:8547983 NCBI chr15:54,780,858...54,911,989 JBrowse link
G Rbp1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 8:99,025,218...99,046,740 JBrowse link
G Rbp4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:235,893,917...235,901,315 JBrowse link
G Rcn1 reticulocalbin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:91,841,052...91,855,295 JBrowse link
G Rel REL proto-oncogene, NF-kB subunit ISO RGD PMID:12897145 RGD:2300264 NCBI chr14:101,891,238...101,922,324 JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit ISO RGD PMID:12897145 RGD:2300264 NCBI chr 1:88,385,717...88,413,380 JBrowse link
G Rpl3 ribosomal protein L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:111,622,255...111,627,640 JBrowse link
G Rpl6 ribosomal protein L6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:41,008,142...41,012,756 JBrowse link
G Rps14 ribosomal protein S14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr18:54,227,854...54,232,638 JBrowse link
G S100a6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 2:178,398,189...178,399,763 JBrowse link
G S100a8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22248470 NCBI chr 2:178,464,095...178,465,223 JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:206,309,715...206,314,070 JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:36,957,302...37,023,982 JBrowse link
G Scd stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 1:253,218,968...253,232,101 JBrowse link
G Selenop selenoprotein P ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 2:52,498,123...52,508,409 JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:24,799,391...24,916,886 JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr18:51,348,282...51,416,448 JBrowse link
G Slc25a10 solute carrier family 25 member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr10:105,765,598...105,775,159 JBrowse link
G Sncg synuclein, gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr16:9,700,513...9,705,751 JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr20:13,130,112...13,145,947 JBrowse link
G Sod1 superoxide dismutase 1 IEP protein:decreased expression:mammary gland (rat) RGD PMID:17157473 RGD:8657018 NCBI chr11:42,942,742...42,948,399 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:98,305,744...98,311,250 JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:84,558,159...84,580,616 JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:102,052,158...102,055,365 JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:86,311,528...86,363,513 JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:15609129 PMID:16316942 PMID:17173897 PMID:20235097 NCBI chr10:86,285,859...86,310,187 JBrowse link
G Stmn1 stathmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:151,964,308...151,970,843 JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9879772 PMID:16316942 NCBI chr 8:103,789,780...103,816,487 JBrowse link
G Tgfa transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr 4:120,175,549...120,258,342 JBrowse link
G Thrsp thyroid hormone responsive ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:161,134,640...161,138,964 JBrowse link
G Tkt transketolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr16:5,723,764...5,748,702 JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:211,661,738...211,798,458 JBrowse link
G Tmem37 transmembrane protein 37 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489049 NCBI chr13:31,184,322...31,191,477 JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489049 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Tpm3 tropomyosin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 2:177,812,534...177,842,661 JBrowse link
G Trps1 transcriptional repressor GATA binding 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:83,806,121...84,032,609 JBrowse link
G Tsc22d1 TSC22 domain family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:58,159,612...58,260,244 JBrowse link
G Tubb2b tubulin, beta 2B class IIb ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr17:30,953,086...30,956,133 JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:14,782,245...14,802,911 JBrowse link
G Ucp2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:164,251,373...164,257,742 JBrowse link
G Vamp8 vesicle-associated membrane protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:104,442,383...104,452,884 JBrowse link
G Wnt1 Wnt family member 1 ISO RGD PMID:10918574 RGD:2298804 NCBI chr 7:131,817,558...131,821,605 JBrowse link
G Wnt3 Wnt family member 3 ISO RGD PMID:10918574 RGD:2298804 NCBI chr10:89,180,224...89,224,195 JBrowse link
G Wnt6 Wnt family member 6 ISO RGD PMID:18649356 RGD:2298845 NCBI chr 9:76,329,882...76,343,523 JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:21,530,463...21,592,172 JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:69,826,404...69,848,702 JBrowse link
Aplasia or Hypoplasia of Breasts and/or Nipples 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprf protein tyrosine phosphatase, receptor type, F ISO ClinVar Annotator: match by term: Breasts and/or nipples, aplasia or hypoplasia of, 2 | ClinVar Annotator: match by term: PTPRF-related condition OMIM
ClinVar
PMID:25741868 PMID:28492532 NCBI chr 5:131,741,959...131,824,000 JBrowse link
aromatase excess syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO ClinVar Annotator: match by term: Gynecomastia, familial ClinVar PMID:2594783 PMID:16804045 PMID:25326637 PMID:25740850 PMID:25741868 More... NCBI chr  X:63,104,771...63,273,934 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO
ISS
ClinVar Annotator: match by term: Aromatase deficiency | ClinVar Annotator: match by term: Aromatase excess syndrome | ClinVar Annotator: match by term: CYP19A1-related condition | ClinVar Annotator: match by term: Familial gynecomastia, due to increased aromatase activity | ClinVar Annotator: match by term: Pseudohermaphroditism, female, due to placental aromatase deficiency
OMIM:139300
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
MouseDO
CTD
PMID:1496995 PMID:1825497 PMID:2973313 PMID:8265607 PMID:8530621 More... NCBI chr 8:63,449,148...63,476,534 JBrowse link
G Gldn gliomedin ISO ClinVar Annotator: match by term: Aromatase deficiency ClinVar PMID:25741868 NCBI chr 8:54,679,015...54,723,198 JBrowse link
bilateral breast cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Bilateral breast carcinoma ClinVar PMID:19781682 PMID:25085752 PMID:25741868 PMID:26689913 PMID:26787654 More... NCBI chr 8:62,724,939...62,829,040 JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:9150151 PMID:11376024 PMID:16683254 PMID:19491284 PMID:20104584 More... NCBI chr10:86,917,693...86,978,012 JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:25741868 NCBI chr12:4,895,092...4,939,340 JBrowse link
G Mc1r melanocortin 1 receptor ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:16809487 PMID:16982779 PMID:24335900 PMID:24982914 PMID:25741868 More... NCBI chr19:68,360,950...68,363,877 JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:23047549 PMID:23621914 PMID:25741868 PMID:26467025 PMID:26689913 More... NCBI chr 6:12,316,190...12,333,505 JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:20852946 PMID:22692731 PMID:24448499 PMID:24556926 PMID:25085752 More... NCBI chr 1:176,665,076...176,689,053 JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:17102082 PMID:19351833 PMID:20208144 PMID:21520333 PMID:23175444 More... NCBI chr 5:158,547,775...158,568,589 JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:26467025 PMID:28492532 PMID:31874108 PMID:33558524 PMID:37460928 NCBI chr 8:28,438,370...28,535,071 JBrowse link
BRANCHIAL ARCH ABNORMALITIES, CHOANAL ATRESIA, ATHELIA, HEARING LOSS, AND HYPOTHYROIDISM SYNDROME term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmt2d lysine methyltransferase 2D ISO ClinVar Annotator: match by term: BRANCHIAL ARCH ABNORMALITIES, CHOANAL ATRESIA, ATHELIA, HEARING LOSS, AND HYPOTHYROIDISM SYNDROME | ClinVar Annotator: match by term: Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome OMIM
ClinVar
PMID:12002153 PMID:24728327 PMID:25590979 PMID:25741868 PMID:28492532 More... NCBI chr 7:129,980,744...130,022,088 JBrowse link
breast adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:17611497 PMID:18954143 PMID:21793738 PMID:23237847 PMID:25741868 More... NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Brca1 BRCA1, DNA repair associated treatment ISO RGD PMID:8589721 RGD:126925966 NCBI chr10:86,917,693...86,978,012 JBrowse link
G Cat catalase ISO RGD PMID:25050522 RGD:9226881 NCBI chr 3:110,297,340...110,329,526 JBrowse link
G Ccne1 cyclin E1 ISO DNA:amplification RGD PMID:18089785 RGD:2289225 NCBI chr 1:99,918,672...99,927,986 JBrowse link
G Ccng1 cyclin G1 ISO mRNA, protein:altered expression:mammary (mouse) RGD PMID:11146550 RGD:2315939 NCBI chr10:25,678,503...25,684,876 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEP mRNA:increased expression:mammary epithelium (rat) RGD PMID:11097088 RGD:7829735 NCBI chr 6:21,093,927...21,103,091 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 no_association ISO RGD PMID:11466624 RGD:2289868 NCBI chr14:81,211,800...81,227,215 JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO mRNA:increased expression:breast RGD PMID:9811352 RGD:2306185 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:2547513 PMID:3627975 PMID:15696205 PMID:17332249 PMID:21063026 More... NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Ksr1 kinase suppressor of ras 1 severity ISO RGD PMID:24909178 RGD:127229932 NCBI chr10:64,459,786...64,596,083 JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA,protein:increased expression:breast RGD PMID:7678777 RGD:2324855 NCBI chr 2:176,933,312...176,938,497 JBrowse link
G Mxi1 MAX interactor 1, dimerization protein IAGP RGD PMID:10849326 RGD:1298988 NCBI chr 1:252,323,915...252,383,682 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Breast adenocarcinoma | ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:15016963 PMID:15520168 PMID:15608678 PMID:15930273 PMID:17673550 More... NCBI chr 2:117,103,643...117,177,411 JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:12068296 NCBI chr 5:13,161,648...13,225,560 JBrowse link
G Slc22a18 solute carrier family 22, member 18 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:9520460 NCBI chr 1:198,670,626...198,694,977 JBrowse link
G Tnf tumor necrosis factor ISO human protein in a rat model RGD PMID:12536235 RGD:14995452 NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar
RGD
PMID:1673792 PMID:1686725 PMID:7881428 PMID:8364550 PMID:10713666 More... RGD:2315939 NCBI chr10:54,798,871...54,810,300 JBrowse link
breast angiosarcoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor ISO DNA:mutation:multiple (human) RGD PMID:32123305 RGD:151665102 NCBI chr14:32,572,031...32,615,204 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO DNA:mutation:multiple (human) RGD PMID:32123305 RGD:151665102 NCBI chr 2:117,103,643...117,177,411 JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B ISO DNA:mutation:multiple (human) RGD PMID:32123305 RGD:151665102 NCBI chr 7:51,953,375...52,034,751 JBrowse link
breast cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit ISO ClinVar Annotator: match by term: Hereditary breast cancer, ABRAXAS1-related | ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 NCBI chr14:8,796,281...8,810,625 JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:insertion/deletion, haplotype RGD PMID:23828384 RGD:8548866 NCBI chr10:91,410,129...91,430,246 JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 disease_progression ISO DNA:deletion
mRNA:increased expression:breast
RGD PMID:28977883 PMID:23512947 RGD:13831299, RGD:13831301 NCBI chr 9:80,115,164...80,164,636 JBrowse link
G Adam28 ADAM metallopeptidase domain 28 exacerbates ISO RGD PMID:19549921 RGD:153298911 NCBI chr15:43,774,463...43,840,726 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing no_association ISO DNA:SNPs: :rs1501299, rs2241766 (human)
protein:decreased expression:serum
RGD PMID:18451143 PMID:17192291 PMID:16019138 PMID:19723917 RGD:8694415, RGD:8694447, RGD:8694425, RGD:8694417 NCBI chr11:91,226,524...91,240,244 JBrowse link
G Adipor1 adiponectin receptor 1 no_association ISO DNA:SNPs: :rs7539542 (human) RGD PMID:18451143 PMID:19723917 RGD:8694415, RGD:8694417 NCBI chr13:48,411,438...48,431,251 JBrowse link
G Adipor2 adiponectin receptor 2 no_association ISO RGD PMID:19723917 RGD:8694417 NCBI chr 4:152,524,604...152,588,848 JBrowse link
G Adm adrenomedullin ISO RGD PMID:16841081 RGD:2325318 NCBI chr 1:174,164,178...174,182,372 JBrowse link
G Adsl adenylosuccinate lyase severity ISO
IEP
protein:increased activity:tumor (human)
protein:increased activity:tumor (rat)
RGD PMID:3690833 PMID:2937404 RGD:1598760, RGD:1598766 NCBI chr 7:114,359,440...114,383,618 JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member disease_progression ISO RGD PMID:16598187 RGD:2325661 NCBI chr 6:52,708,602...52,729,378 JBrowse link
G Agt angiotensinogen susceptibility ISO DNA:polymorphism: :p.M235T (human)
protein:increased expression:serum
DNA:polymorphisms, haplotypes: :p.T174M, p.M235T (human)
RGD PMID:16823505 PMID:23374911 PMID:23828384 RGD:8548861, RGD:8548901, RGD:8548866 NCBI chr19:69,426,540...69,447,017 JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO DNA:polymorphism, haplotype: :1166A>C (human) RGD PMID:23828384 RGD:8548866 NCBI chr17:34,383,397...34,435,523 JBrowse link
G Aif1l allograft inflammatory factor 1-like severity ISO RGD PMID:30233209 RGD:13842475 NCBI chr 3:15,229,476...15,254,033 JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO mRNA:increased expression:breast RGD PMID:25526449 RGD:27226689 NCBI chr 5:135,329,605...135,367,037 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Breast cancer, somatic
ClinVar Annotator: match by term: Malignant tumor of breast
OMIM
ClinVar
PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type disease_progression ISO mRNA:increased expression:breast RGD PMID:19282568 RGD:2315607 NCBI chr10:54,958,263...54,970,542 JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:polymorphism:g.-4800A>G (human) RGD PMID:18843019 RGD:2313902 NCBI chr12:10,785,254...10,809,295 JBrowse link
G Amh anti-Mullerian hormone onset ISO RGD PMID:19820206 RGD:2315637 NCBI chr 7:9,557,451...9,559,867 JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 disease_progression ISO mRNA:increased expression:breast: RGD PMID:17016666 RGD:9684946 NCBI chr 4:119,590,770...119,778,232 JBrowse link
G Anxa7 annexin A7 disease_progression ISO protein:increased expression:breast RGD PMID:15073110 RGD:2292655 NCBI chr15:3,821,798...3,849,659 JBrowse link
G Aopep aminopeptidase O ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:7689011 PMID:08128956 PMID:08844212 PMID:8882868 PMID:9521584 More... NCBI chr17:1,817,001...2,133,008 JBrowse link
G Apc APC regulator of WNT signaling pathway ISS
ISO
OMIM:114480
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant tumor of breast
MouseDO
ClinVar
PMID:8940262 PMID:9288102 PMID:9585599 PMID:9724771 PMID:9731522 More... NCBI chr18:26,138,382...26,196,021 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility ISO DNA:polymorphism: :p.D148E (human) RGD PMID:18701435 RGD:2315661 NCBI chr15:24,144,595...24,146,785 JBrowse link
G Apoc3 apolipoprotein C3 disease_progression ISO RGD PMID:28715644 RGD:153350084 NCBI chr 8:46,531,478...46,533,658 JBrowse link
G Apoe apolipoprotein E susceptibility
no_association
ISO DNA:polymorphism:exon:
DNA:polymprphism:exon:
RGD PMID:15830139 PMID:16752225 RGD:7495789, RGD:7771592 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Areg amphiregulin ISO RGD PMID:16438846 RGD:2292658 NCBI chr14:17,256,384...17,265,641 JBrowse link
G Arid1a AT-rich interaction domain 1A treatment ISO human cells in mouse model RGD PMID:26069190 RGD:11072938 NCBI chr 5:151,192,014...151,269,291 JBrowse link
G Asf1b anti-silencing function 1B histone chaperone disease_progression ISO RGD PMID:21179005 RGD:9586017 NCBI chr19:24,181,024...24,195,604 JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
OMIM
RGD
PMID:1160401 PMID:1739330 PMID:1739584 PMID:2166257 PMID:2677459 More... RGD:1643350 NCBI chr 8:62,724,939...62,829,040 JBrowse link
G Atr ATR serine/threonine kinase ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:28492532 NCBI chr 8:105,306,299...105,403,742 JBrowse link
G Axin2 axin 2 ISO ClinVar Annotator: match by term: Malignant breast neoplasm
ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar PMID:21541676 PMID:25236910 PMID:25741868 PMID:26467025 PMID:28492532 More... NCBI chr10:94,393,379...94,426,579 JBrowse link
G Bad BCL2-associated agonist of cell death disease_progression ISO RGD PMID:17004114 RGD:2292674 NCBI chr 1:213,562,719...213,572,034 JBrowse link
G Bag1 BAG cochaperone 1 disease_progression ISO protein:increased expression:breast RGD PMID:11181661 RGD:2293888 NCBI chr 5:60,864,476...60,877,059 JBrowse link
G Bard1 BRCA1 associated RING domain 1 severity
susceptibility
no_association
ISO
ISS
protein:increased expression, altered localization:breast
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
OMIM:114480
DNA:polymorphism: :p.C557S (human)
DNA:polymorphisms: :p.P24S, p.R378S (human)
DNA:polymorphisms: :multiple (human)
DNA:polymorphisms: :p.V507M, p.C557S (human)
DNA:polymorphism: :p.V507M (human)
ClinVar
MouseDO
OMIM
RGD
PMID:9425226 PMID:9536098 PMID:11807980 PMID:14550946 PMID:15342711 More... RGD:2315727, RGD:2315714, RGD:2315713, RGD:2315715, RGD:2315716, RGD:2315717, RGD:2315729 NCBI chr 9:80,069,960...80,144,167 JBrowse link
G Bax BCL2 associated X, apoptosis regulator disease_progression ISO RGD PMID:17626754 RGD:1643353 NCBI chr 1:105,076,472...105,081,906 JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member severity ISO protein:increased expression:breast, cytosol (human) RGD PMID:15448007 RGD:8547748 NCBI chr19:39,679,215...39,713,907 JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor ISO DNA:amplification:cds (human) RGD PMID:12169396 RGD:9850147 NCBI chr 2:190,692,503...190,700,386 JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor ISO RGD PMID:16855396 RGD:2317828 NCBI chr10:70,711,084...71,170,492 JBrowse link
G Bcl2l1 Bcl2-like 1 ISO RGD PMID:16850344 RGD:1643481 NCBI chr 3:161,713,777...161,764,844 JBrowse link
G Becn1 beclin 1 disease_progression ISO RGD PMID:33292020 RGD:155641236 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Bik BCL2-interacting killer ISO RGD PMID:14633680 RGD:14394816 NCBI chr 7:114,672,277...114,691,296 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 ISO RGD PMID:12218061 RGD:1643528 NCBI chr 8:13,253,697...13,273,672 JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO mRNA:increased expression:breast RGD PMID:17004110 RGD:1643590 NCBI chr15:22,098,191...22,113,145 JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO mRNA:decreased expression:breast RGD PMID:17004110 RGD:1643590 NCBI chr17:26,523,704...26,785,558 JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO mRNA:increased expression:breast RGD PMID:17004110 RGD:1643590 NCBI chr 3:182,059,318...182,135,273 JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:22703879 PMID:23399955 PMID:24033266 PMID:24448499 PMID:24728327 More... NCBI chr16:9,740,751...9,786,861 JBrowse link
G Brca1 BRCA1, DNA repair associated susceptibility ISO
ISS
DNA:mutation
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, post-chemotherapy poor survival in | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
DNA:loss of heterozygosity,deletion, duplication: :c.1504_1508delTTAAA, c.211dupA, c.5266dupC (human)
mRNA, protein:splice variant
OMIM:114480
mRNA:allelic imbalance:lymphocyte
DNA:hypermethylation:promoter
ClinVar
MouseDO
RGD
PMID:202008 PMID:1157798 PMID:1673748 PMID:2010458 PMID:2504116 More... RGD:1599497, RGD:127284852, RGD:126925963, RGD:734655, RGD:2293153, RGD:2293151 NCBI chr10:86,917,693...86,978,012 JBrowse link
G Brca2 BRCA2, DNA repair associated ISO
ISS
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
OMIM:114480
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
OMIM
MouseDO
PMID:234495 PMID:668580 PMID:1169856 PMID:1446381 PMID:2200631 More... NCBI chr12:4,895,092...4,939,340 JBrowse link
G Brip1 BRCA1 interacting DNA helicase 1 onset
susceptibility
ISO DNA:missense mutations:cds:p.P47A, p.M299I (human)
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant tumor of breast
DNA:snps, haplotype:introns:c.1935+977T>C, c.1473+3729A>G, c.1340+109G>A (rs11871753, rs16945628, rs2191248) (human)
DNA:mutations:multiple (human)
DNA:snp:3' utr:C>A (rs7220740) (human)
DNA:missense mutation:cds:p.Q944E (human)
OMIM
ClinVar
RGD
PMID:2455662 PMID:3375802 PMID:9536098 PMID:11301010 PMID:12565990 More... RGD:1600525, RGD:11252109, RGD:11252107, RGD:11252100, RGD:11251779 NCBI chr10:71,402,035...71,528,083 JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO protein:decreased expression:breast, nucleus RGD PMID:16849553 RGD:2289068 NCBI chr13:48,083,931...48,087,690 JBrowse link
G C8h11orf65 similar to human chromosome 11 open reading frame 65 ISO ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar PMID:1160401 PMID:2166257 PMID:4012663 PMID:6504056 PMID:7792600 More... NCBI chr 8:53,796,033...53,825,277 JBrowse link
G Casp3 caspase 3 severity ISO protein:decreased expression:breast RGD PMID:18227733 PMID:23979166 RGD:2293092, RGD:13209143 NCBI chr16:52,395,539...52,413,794 JBrowse link
G Casp7 caspase 7 disease_progression ISO RGD PMID:23979166 RGD:13209143 NCBI chr 1:265,442,647...265,481,938 JBrowse link
G Casp8 caspase 8 ISO ClinVar Annotator: match by term: BREAST CANCER, PROTECTION AGAINST OMIM
ClinVar
PMID:15601643 PMID:15998955 PMID:17293864 PMID:24033266 PMID:25741868 More... NCBI chr 9:67,747,109...67,806,699 JBrowse link
G Casp9 caspase 9 ISO mRNA:decreased expression:breast RGD PMID:17011986 RGD:2290492
G Casr calcium-sensing receptor ISO ClinVar Annotator: match by term: Malignant breast neoplasm ClinVar PMID:8636323 PMID:10023897 PMID:10217111 PMID:10912749 PMID:11161843 More... NCBI chr11:77,738,398...77,813,639 JBrowse link
G Cav1 caveolin 1 no_association
disease_progression
ISO
ISS
DNA, protein:hypermethylation, decreased expression:promoter, breast
OMIM:114480
DNA:SNPs: :multiple
DNA:SNPs: :14713G>A (rs3807987), 29107T>A (rs7804372) (human)
MouseDO
RGD
PMID:15375584 PMID:21965771 PMID:21965771 PMID:21585620 RGD:2289105, RGD:8661769, RGD:8661769, RGD:8661766 NCBI chr 4:46,606,538...46,639,616 JBrowse link
G Cbx7 chromobox 7 severity ISO human gene in a mouse model RGD PMID:25351982 RGD:11352704 NCBI chr 7:113,341,030...113,358,716 JBrowse link
G Ccnb1 cyclin B1 disease_progression ISO RGD PMID:19223507 PMID:19957331 RGD:2315937, RGD:2315934 NCBI chr 2:33,646,252...33,655,225 JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr 4:161,653,048...161,675,422 JBrowse link
G Ccne1 cyclin E1 disease_progression ISO RGD PMID:17483245 RGD:2289231 NCBI chr 1:99,918,672...99,927,986 JBrowse link
G Ccng1 cyclin G1 treatment IEP RGD PMID:23791885 RGD:151356928 NCBI chr10:25,678,503...25,684,876 JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO DNA:frameshift mutation: :p.S185_T195del (rs333) (human)
mRNA:increased expression:breast
RGD PMID:14597737 PMID:24301790 RGD:8551810, RGD:8551816 NCBI chr 8:132,629,097...132,660,980 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 disease_progression ISO RGD PMID:21624121 RGD:7483628 NCBI chr 1:55,022,037...55,055,857 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) disease_progression ISO RGD PMID:18676748 PMID:15102687 RGD:2326166, RGD:2326170 NCBI chr13:44,409,574...44,438,913 JBrowse link
G Cdc25c cell division cycle 25C ISO protein:increased expression:breast RGD PMID:15567944 RGD:4105448 NCBI chr18:26,608,483...26,630,292 JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:increased expression:breast (human) RGD PMID:29221126 RGD:150539444 NCBI chr13:55,357,226...55,449,690 JBrowse link
G Cdh1 cadherin 1 ISO ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, lobular | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
OMIM
PMID:1722187 PMID:2403327 PMID:2449335 PMID:8075649 PMID:8557030 More... NCBI chr19:51,402,178...51,471,572 JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation
protein:decreased expression:breast duct:
RGD PMID:17764565 PMID:8673923 RGD:2293542, RGD:734735 NCBI chr19:46,349,562...47,387,462 JBrowse link
G Cdk1 cyclin-dependent kinase 1 disease_progression
susceptibility
ISO DNA:SNP:intron:rs16941635 (human) RGD PMID:17956886 PMID:19377877 RGD:2708463, RGD:2683526 NCBI chr20:19,265,252...19,280,456 JBrowse link
G Cdk13 cyclin-dependent kinase 13 severity ISO RGD PMID:33292020 RGD:155641236 NCBI chr17:51,945,975...52,040,218 JBrowse link
G Cdk2 cyclin dependent kinase 2 disease_progression ISO RGD PMID:18236071 RGD:2293557 NCBI chr 7:1,714,392...1,721,964 JBrowse link
G Cdk4 cyclin-dependent kinase 4 disease_progression ISO RGD PMID:16440198 RGD:2293576 NCBI chr 7:64,771,453...64,774,891 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO protein:increased localization:cytoplasm
DNA:SNP
RGD PMID:18030569 PMID:12244302 PMID:18174243 RGD:2293594, RGD:734746, RGD:2289652 NCBI chr 4:169,491,273...169,496,500 JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A susceptibility ISO DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 5:109,100,763...109,114,448 JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar NCBI chr 5:109,123,308...109,134,906 JBrowse link
G Cfb complement factor B treatment ISO RGD PMID:15274022 RGD:7411730 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Cga glycoprotein hormones, alpha polypeptide disease_progression ISO RGD PMID:11687975 RGD:2293635 NCBI chr 5:54,283,109...54,295,464 JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ISO mRNA:increased expression:breast (human) RGD PMID:28486105 RGD:153323299 NCBI chr 4:159,584,623...159,617,867 JBrowse link
G Chek2 checkpoint kinase 2 susceptibility ISO DNA:missense mutations:p.I157T and p.S428F
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Cancer breast | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, early-onset | ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant tumor of breast
DNA:loss of heterozygosity
ClinVar
RGD
PMID:2936834 PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 More... RGD:2289703, RGD:2289706 NCBI chr12:51,448,838...51,481,159 JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:12889595 RGD:4892603 NCBI chr13:45,641,802...45,649,787 JBrowse link
G Clu clusterin disease_progression ISO DNA:snp:promoter:g.27611345C>G (rs9331888) (human) RGD PMID:22037783 RGD:8963167 NCBI chr15:40,161,068...40,200,315 JBrowse link
G Comt catechol-O-methyltransferase disease_progression
susceptibility
no_association
ISO DNA:polymorphism: :p.V158M
mRNA:increased expression:breast
RGD PMID:17429315 PMID:17507616 PMID:17562079 PMID:15285606 RGD:2289715, RGD:2289712, RGD:2289710, RGD:2289721 NCBI chr11:96,072,371...96,091,956 JBrowse link
G Crp C-reactive protein ISO protein:increased expression:nipple aspirate fluid RGD PMID:21139810 RGD:9491787 NCBI chr13:87,694,062...87,695,978 JBrowse link
G Csf1 colony stimulating factor 1 ISO RGD PMID:18172291 RGD:2293639 NCBI chr 2:198,065,400...198,084,774 JBrowse link
G Csf1r colony stimulating factor 1 receptor disease_progression
treatment
ISO RGD PMID:14734466 PMID:25385645 RGD:2293711, RGD:150524304 NCBI chr18:56,834,152...56,860,804 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 ISO RGD PMID:11827167 RGD:727632 NCBI chr 3:161,170,295...161,217,073 JBrowse link
G Ctcf CCCTC-binding factor severity ISO protein:alternative form, increased expression:breast tumor (human) RGD PMID:19737964 RGD:151356756 NCBI chr19:50,431,478...50,481,013 JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO protein:increased expression:serum:
DNA:SPNs:multiple:
RGD PMID:20482250 PMID:17825114 RGD:7411684, RGD:7421502 NCBI chr 9:69,812,859...69,819,959 JBrowse link
G Ctsb cathepsin B ISO protein:increased expression:breast carcinoma, cytosol (human) RGD PMID:9508185 RGD:2315523 NCBI chr15:41,565,607...41,586,479 JBrowse link
G Ctsd cathepsin D ISO human gene in a mouse model RGD PMID:12140763 RGD:1547890 NCBI chr 1:206,956,945...206,968,821 JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 susceptibility ISO DNA:polymporhism:(rs8190370)(human) RGD PMID:25225034 RGD:11040537 NCBI chr 7:116,186,729...116,204,290 JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO DNA:transition:5' utr:-34T>C rs743572 (human)
ClinVar Annotator: match by term: Breast cancer, susceptibility to
ClinVar
RGD
PMID:1740503 PMID:10720067 PMID:14747197 PMID:16121340 PMID:17192295 More... RGD:4889142 NCBI chr 1:245,535,462...245,543,148 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment ISO DNA:repeat::(TTTA)10 (human)
DNA:SNP:cds:rs700518 (human)
RGD PMID:16875543 PMID:7053713 PMID:23643682 RGD:2301046, RGD:7257716, RGD:7257707 NCBI chr 8:63,449,148...63,476,534 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 no_association ISO DNA:SNP::rs4646903 (human)
DNA:polymorphisms: :multiple
DNA:transitions:exon, 3' utr:4889A>G, 6235T>C (human)
DNA:SNP: :p.I462V (rs1048943) (human)
DNA:SNP:3' utr:6235T>C (human)
RGD PMID:18497059 PMID:9426059 PMID:12496044 PMID:17603290 PMID:21418988 RGD:2301045, RGD:8552810, RGD:8552799, RGD:8552794, RGD:8552792 NCBI chr 8:66,991,940...66,998,014 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO RGD PMID:18497059 RGD:2301045 NCBI chr 8:66,971,261...66,978,149 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 susceptibility ISO DNA:snp:cds:p.A119S (human) RGD PMID:10739169 RGD:7829734 NCBI chr 6:21,093,927...21,103,091 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 treatment ISO DNA:haplotype: : RGD PMID:26799162 RGD:124713411 NCBI chr 1:247,879,058...247,916,804 JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 no_association ISO RGD PMID:15180491 RGD:5685600 NCBI chr12:14,321,771...14,343,886 JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:breast cancer tissue (human) RGD PMID:31578591 RGD:151347435 NCBI chr20:3,047,269...3,069,277 JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked exacerbates ISO protein:increased expression:breast, nucleus (human) RGD PMID:28761359 RGD:151356502 NCBI chr  X:9,479,532...9,493,169 JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 PMID:32714280 NCBI chr 6:123,627,529...123,692,278 JBrowse link
G Dll4 delta like canonical Notch ligand 4 disease_progression ISO RGD PMID:20167860 RGD:155641260 NCBI chr 3:126,770,945...126,780,769 JBrowse link
G Dusp1 dual specificity phosphatase 1 disease_progression
severity
ISO protein:increased expression:T cell
protein:increased expression:mammary gland
DNA:hypermethylation:promoter
RGD PMID:9724088 PMID:12618338 PMID:19417026 PMID:22333693 RGD:2298697, RGD:7495809, RGD:7495851, RGD:7495850 NCBI chr10:17,184,853...17,187,646 JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO protein:increased expression:mammary gland RGD PMID:12618338 RGD:7495809 NCBI chr 7:35,979,502...35,983,834 JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 ISO DNA:amplification RGD PMID:12160478 RGD:2289857 NCBI chr 7:75,810,950...75,828,902 JBrowse link
G Egfr epidermal growth factor receptor ISO mRNA:increased expression:breast RGD PMID:17465220 RGD:2289949 NCBI chr14:95,378,626...95,551,358 JBrowse link
G Egr1 early growth response 1 ISO
IEP
protein:decreased expression:tumor (human)
protein:decreased expression:tumor (rat)
RGD PMID:9212230 PMID:9212230 RGD:5131943, RGD:5131943 NCBI chr18:26,737,078...26,740,877 JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H ISO DNA:amplification RGD PMID:10362802 RGD:2289902 NCBI chr 7:84,980,891...85,064,284 JBrowse link
G Eng endoglin treatment ISO human tumor in mouse model RGD PMID:11691802 RGD:7248784 NCBI chr 3:36,332,190...36,370,324 JBrowse link
G Epo erythropoietin ISO protein:increased expression:breast: RGD PMID:12118093 RGD:11041669 NCBI chr12:19,204,258...19,207,948 JBrowse link
G Epor erythropoietin receptor ISO protein:increased expression:breast: RGD PMID:12118093 RGD:11041669 NCBI chr 8:28,765,738...28,770,371 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISS OMIM:114480 MouseDO NCBI chr10:83,907,491...83,931,365 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:3' utr:c.8092C>A (human) RGD PMID:15958648 RGD:13207317 NCBI chr 1:78,971,310...79,007,963 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:haplotype:cds:6540G>A(D312N),18880A>C(p.K751Q)(human) RGD PMID:15598761 RGD:12880387 NCBI chr 1:88,161,342...88,175,102 JBrowse link
G Espl1 extra spindle pole bodies like 1, separase ISS OMIM:114480 MouseDO NCBI chr 7:135,302,460...135,329,570 JBrowse link
G Esr1 estrogen receptor 1 susceptibility
no_association
disease_progression
treatment
ISO
ISS
DNA:SNPs, haplotypes:promoter, exon
OMIM:114480
DNA:SNP: :908A>G (p.K303R) (human)
DNA:SNP:exon:2014G>A (human)
DNA:amplification
DNA:SNPs: :rs2234693, rs9340799 (human)
OMIM
MouseDO
RGD
PMID:15604249 PMID:15034868 PMID:17553133 PMID:19636371 PMID:19320640 More... RGD:8552978, RGD:8553053, RGD:8553052, RGD:8552982, RGD:8552981, RGD:8552980, RGD:8552979 NCBI chr 1:43,511,685...43,904,454 JBrowse link
G Esr2 estrogen receptor 2 treatment
susceptibility
no_association
IDA
ISO
DNA:silent mutation:exon:g.1176C>G (rs1256054) (human)
DNA:snps:multiple (human)
DNA:snps:intron, exon:g.14206C>T, g.33390C>G (rs1256054) (human)
DNA:snps, haplotype:multiple (human)
DNA:repeat:intron:IVS5(CA)9-31 (human)
DNA:snps, haplotype:exons:g.1082G>A, g.1730G>A, A>G (rs1256049, rs4986938, rs928554) (human)
DNA:snps:5' utr, exon, 3' utr:-12214C>T (rs1271572), A>G (rs928554), A>G (rs4986938) (human)
associated with Benign Breast Disease;DNA:snp:3' utr:*5772A>G (rs8018687) (human)
DNA:snp:promoter:g.-13950C>T (rs2987983) (human)
DNA:repeat:3' utr:(CA)10-27 (human)
RGD PMID:23700476 PMID:20604969 PMID:19321582 PMID:14633679 PMID:15604249 More... RGD:7364946, RGD:8694116, RGD:8694110, RGD:8694103, RGD:8552978, RGD:8694096, RGD:8694090, RGD:8693382, RGD:8693380, RGD:8693347, RGD:8552977 NCBI chr 6:100,589,553...100,645,240 JBrowse link
G Ext1 exostosin glycosyltransferase 1 ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:28492532 NCBI chr 7:86,265,651...86,544,488 JBrowse link
G F10 coagulation factor X ISO DNA:SNP: :rs3093261 (human) RGD PMID:25407022 RGD:10449101 NCBI chr16:83,170,973...83,190,280 JBrowse link
G F11r F11 receptor disease_progression ISO RGD PMID:19533747 RGD:7488915 NCBI chr13:86,406,229...86,429,819 JBrowse link
G F5 coagulation factor V no_association ISO DNA:SNPs: :multiple
DNA:SNPs: :rs6025 (human)
RGD PMID:25407022 PMID:25407022 RGD:10449101, RGD:10449101 NCBI chr13:79,046,657...79,116,247 JBrowse link
G F7 coagulation factor VII ISO mRNA:increased expression:breast (human) RGD PMID:19996301 RGD:11049547 NCBI chr16:83,191,896...83,202,775 JBrowse link
G Fanca FA complementation group A ISO DNA:missense mutations, SNP:exon, 5' utr:p.T266A (c.796A>G, rs7190823), p.G501S (c.1501G>A, rs2239359), c.-1C>A (human)
ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
RGD
PMID:24728327 PMID:25741868 PMID:28492532 PMID:23021409 RGD:11344892 NCBI chr19:68,210,562...68,271,080 JBrowse link
G Fancb FA complementation group B ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 PMID:33558524 NCBI chr  X:33,035,387...33,051,993 JBrowse link
G Fancc FA complementation group C ISO DNA:mutations:exons:
ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
RGD
PMID:7492758 PMID:7689011 PMID:8081385 PMID:08128956 PMID:08348157 More... RGD:11046263 NCBI chr17:1,686,374...1,818,672 JBrowse link
G Fancd2 FA complementation group D2 ISO ClinVar Annotator: match by term: Malignant tumor of breast
DNA:SNP, haplotype: :rs2272125 (human)
ClinVar
RGD
PMID:24728327 PMID:25741868 PMID:28492532 PMID:33558524 PMID:23897704 More... RGD:10769361, RGD:11344909 NCBI chr 4:148,234,633...148,299,035 JBrowse link
G Fance FA complementation group E ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 NCBI chr20:6,369,416...6,386,631 JBrowse link
G Fancf FA complementation group F ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr 1:110,585,054...110,587,870 JBrowse link
G Fanci FA complementation group I ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 PMID:33558524 NCBI chr 1:142,736,636...142,792,999 JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO DNA:polymorphism:promoter:-1377G>A RGD PMID:17183065 RGD:2290054 NCBI chr 1:241,212,155...241,245,774 JBrowse link
G Fen1 flap structure-specific endonuclease 1 disease_progression ISO DNA,mRNA:hypomethylation,increased expression:promoter,breast RGD PMID:19010819 RGD:6484520 NCBI chr 1:216,270,016...216,274,873 JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression
susceptibility
ISO protein:increased expression:mammary gland fluid/secretion RGD PMID:14715109 PMID:12184408 RGD:8655549, RGD:8655587 NCBI chr 2:122,164,454...122,218,796 JBrowse link
G Fgf8 fibroblast growth factor 8 ISO RGD PMID:10023681 RGD:2289344 NCBI chr 1:244,584,477...244,590,578 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates ISO RGD PMID:17529973 PMID:23185502 PMID:17529967 RGD:2289658, RGD:155663674, RGD:2289657 NCBI chr 1:194,175,703...194,280,914 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO RGD PMID:11329138 RGD:2289867 NCBI chr14:81,211,800...81,227,215 JBrowse link
G Fh fumarate hydratase ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar NCBI chr13:90,056,565...90,082,450 JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP protein:increased expression:mammary carcinoma cells RGD PMID:10604730 RGD:2289937 NCBI chr12:12,333,050...12,504,750 JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO RGD PMID:27524420 RGD:151665821 NCBI chr 6:75,099,907...75,136,534 JBrowse link
G Fubp1 far upstream element binding protein 1 exacerbates ISO protein:increased expression:breast (human) RGD PMID:27157613 RGD:151361193 NCBI chr 2:243,819,529...243,846,544 JBrowse link
G Ghr growth hormone receptor ISO protein:increased expression:serum:cases versus controls (p<0.01) (human) RGD PMID:17287408 RGD:2301716 NCBI chr 2:52,541,452...52,804,960 JBrowse link
G Ghrh growth hormone releasing hormone ISO protein:increased expression:tumor:colloid, lobular, and infiltrating ductal carcinomas RGD PMID:1973621 RGD:2289972 NCBI chr 3:145,992,762...146,012,528 JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 severity ISO RGD PMID:17692113 RGD:2292541 NCBI chr15:41,972,482...41,976,690 JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO DNA:repeat:CDS: (human) RGD PMID:14744747 RGD:152995457 NCBI chr 8:117,905,462...117,906,588 JBrowse link
G Grb2 growth factor receptor bound protein 2 treatment ISO RGD PMID:17372910 RGD:13504751 NCBI chr10:101,380,354...101,448,138 JBrowse link
G Gstm1 glutathione S-transferase mu 1 treatment ISO RGD PMID:23812950 PMID:15302996 RGD:10755330, RGD:14700967 NCBI chr 2:198,338,005...198,346,007 JBrowse link
G Gstp1 glutathione S-transferase pi 1 treatment ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:23812950 RGD:10755330 NCBI chr 1:210,767,237...210,770,242 JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion RGD PMID:10564681 RGD:2293799 NCBI chr20:12,856,068...12,873,020 JBrowse link
G H19 H19 imprinted maternally expressed transcript susceptibility ISO DNA:SNP RGD PMID:18708391 RGD:2306170 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Hfe homeostatic iron regulator susceptibility
no_association
ISO DNA:missense mutation:cds:p.C282Y (human)
DNA:missense mutations, haplotype:cds:p.H63D, p.S65C, p.C282Y (human)
RGD PMID:14973098 PMID:15894659 RGD:8694348, RGD:8694349 NCBI chr17:41,841,302...41,849,359 JBrowse link
G Hgf hepatocyte growth factor ISS OMIM:114480 MouseDO NCBI chr 4:19,628,902...19,700,467 JBrowse link
G Hmmr hyaluronan-mediated motility receptor susceptibility ISO ClinVar Annotator: match by term: Breast cancer, susceptibility to ClinVar
OMIM
PMID:25741868 NCBI chr10:25,635,249...25,665,389 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum: RGD PMID:7686390 RGD:11520780 NCBI chr 8:27,829,688...27,841,618 JBrowse link
G Ifng interferon gamma susceptibility ISO DNA:repeats:intron: RGD PMID:15900487 RGD:8157615 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Igf1 insulin-like growth factor 1 susceptibility IEP protein:increased expression:serum (rat) RGD PMID:17584969 RGD:2315650 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein: increased expression RGD PMID:21047775 RGD:7242794 NCBI chr 1:130,959,787...131,248,664 JBrowse link
G Igf2 insulin-like growth factor 2 ISO RGD PMID:18719053 RGD:2311512 NCBI chr 1:197,814,409...197,831,802 JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 no_association ISO higher serum expression in cases vs controls but association not significant in multivariate analysis (human)
protein:decreased expression:serum:in patients with breast cancer versus benign breast disease (p=0.001) (human)
RGD PMID:17287408 PMID:10069662 RGD:2301716, RGD:2301715 NCBI chr14:86,261,277...86,266,344 JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 no_association ISO protein:decreased expression:serum RGD PMID:15298948 PMID:10069662 PMID:17287408 PMID:12925957 RGD:2290011, RGD:2301715, RGD:2301716, RGD:2290009 NCBI chr14:86,270,208...86,277,944 JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 no_association ISO lower serum expression in cases vs controls but association not significant in multivariate analysis (human)
protein:decreased expression:serum:in patients with breast cancer versus benign breast disease (p=0.016) (human)
RGD PMID:17287408 PMID:10069662 RGD:2301716, RGD:2301715 NCBI chr 7:133,276,309...133,280,944 JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 ameliorates ISO protein:decreased expression:breast (human) RGD PMID:34606580 RGD:401960874 NCBI chr14:30,737,414...30,797,317 JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta susceptibility ISO DNA:SNPs: :multiple RGD PMID:22562547 RGD:6484541 NCBI chr16:76,021,968...76,075,717 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 treatment ISO RGD PMID:11748276 PMID:17438063 RGD:8549514, RGD:8549557 NCBI chr  X:115,814,620...115,886,080 JBrowse link
G Il18 interleukin 18 no_association ISO protein:increased expression:serum
DNA:SNP:promoter:-607C>A (rs1946518) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
RGD PMID:12209760 PMID:19152241 PMID:19152241 RGD:8655866, RGD:8655899, RGD:8655899 NCBI chr 8:59,802,072...59,829,275 JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism:promoter:-31T>C (human) RGD PMID:21653279 RGD:7401222 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il6 interleukin 6 susceptibility ISO DNA:polymorphism::rs2069832(human) RGD PMID:17594514 RGD:7829720 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Insr insulin receptor severity ISO protein:increased expression:tumor:higher expression associated with favorable prognostic markers and increased disease-free survival (P=0.027) RGD PMID:17221153 PMID:8518410 RGD:2290447, RGD:2290465 NCBI chr12:5,991,135...6,129,275 JBrowse link
G Itga1 integrin subunit alpha 1 ISO protein:decreased expression:tumor:down-regulated in tumors lacking a basement membrane (human) RGD PMID:9408292 RGD:2302120 NCBI chr 2:48,379,181...48,545,336 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:16733206 RGD:2290479 NCBI chr 5:115,009,900...115,012,993 JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO mRNA:increased expression:breast (human) RGD PMID:22199269 RGD:9586031 NCBI chr 9:6,799,101...6,903,616 JBrowse link
G Kat5 lysine acetyltransferase 5 severity ISO mRNA:altered expression:breast (human) RGD PMID:22199269 RGD:9586031 NCBI chr 1:212,325,089...212,332,640 JBrowse link
G Kat6b lysine acetyltransferase 6B ISO DNA:missense mutations:cds:p.D1516Y, p.R1577C (human) RGD PMID:23800003 RGD:9590339 NCBI chr15:2,638,885...2,811,977 JBrowse link
G Kat7 lysine acetyltransferase 7 severity ISO protein:increased expression:breast (human) RGD PMID:21040551 RGD:9681004 NCBI chr10:80,221,519...80,255,590 JBrowse link
G Kat8 lysine acetyltransferase 8 severity ISO mRNA:increased expression:breast (human) RGD PMID:22199269 RGD:9586031 NCBI chr 1:191,954,827...191,967,107 JBrowse link
G Kdm1a lysine demethylase 1A severity ISO
IEP
mRNA:increased expression:breast (human)
protein:increased expression:breast (rat)
RGD PMID:22199269 PMID:23516587 RGD:9586031, RGD:9588313 NCBI chr 5:148,782,976...148,838,319 JBrowse link
G Kdm3b lysine demethylase 3B severity ISO mRNA:decreased expression:breast (human) RGD PMID:23266085 RGD:9586731 NCBI chr18:26,380,859...26,436,701 JBrowse link
G Kdm4a lysine demethylase 4A severity ISO mRNA:altered expression:breast (human) RGD PMID:22199269 RGD:9586031 NCBI chr 5:131,672,754...131,719,534 JBrowse link
G Kdm4b lysine demethylase 4B severity
treatment
ISO mRNA:decreased expression:breast (human)
human gene in a mouse model
RGD PMID:21445275 PMID:21445275 RGD:9587754, RGD:9587754 NCBI chr 9:1,158,737...1,237,233 JBrowse link
G Kdm4c lysine demethylase 4C severity ISO DNA:snp:cds:p.D396N (rs2296067) (human) RGD PMID:24952432 RGD:9587745 NCBI chr 5:88,100,710...88,306,821 JBrowse link
G Kdm5a lysine demethylase 5A severity ISO mRNA:decreased expression:breast (human) RGD PMID:23266085 RGD:9586731 NCBI chr 4:153,565,909...153,643,912 JBrowse link
G Kdm5b lysine demethylase 5B treatment ISO human gene in a mouse model RGD PMID:21369698 RGD:9587774 NCBI chr13:46,001,589...46,073,868 JBrowse link
G Kdm5c lysine demethylase 5C severity ISO mRNA:altered expression:breast (human) RGD PMID:22199269 RGD:9586031 NCBI chr  X:21,345,459...21,387,045 JBrowse link
G Kdm6a lysine demethylase 6A severity ISO mRNA:increased expression:breast (human) RGD PMID:22199269 PMID:23266085 RGD:9586031 RGD:9586731 NCBI chr  X:6,920,374...7,060,027 JBrowse link
G Kdm8 lysine demethylase 8 ISO mRNA:increased expression:breast (human) RGD PMID:20457893 RGD:9587844 NCBI chr 1:180,013,969...180,028,829 JBrowse link
G Kdr kinase insert domain receptor ISO RGD PMID:10371349 RGD:2291951 NCBI chr14:32,572,031...32,615,204 JBrowse link
G Kif1b kinesin family member 1B ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:18334619 PMID:24469107 PMID:24694336 PMID:25741868 PMID:28492532 NCBI chr 5:164,890,778...165,025,848 JBrowse link
G Kiss1r KISS1 receptor severity ISO RGD PMID:17914099 RGD:2292123 NCBI chr 7:9,785,135...9,790,283 JBrowse link
G Klc1 kinesin light chain 1 ISO ClinVar Annotator: match by term: Breast cancer, susceptibility to ClinVar PMID:12023982 NCBI chr 6:130,823,416...130,866,729 JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 ISO protein:increased expression:serum:in patients with breast cancer versus benign breast disease (p=0.025) RGD PMID:10069662 RGD:2301715 NCBI chr 1:94,402,993...94,407,052 JBrowse link
G Klk4 kallikrein-related peptidase 4 disease_progression
severity
ISO mRNA, protein:increased expression:breast RGD PMID:18687310 PMID:19190825 RGD:2314853, RGD:2314852 NCBI chr 1:94,344,195...94,349,425 JBrowse link
G Kmt2b lysine methyltransferase 2B severity ISO mRNA:increased expression:breast (human) RGD PMID:24491801 RGD:9588564 NCBI chr 1:85,821,700...85,840,987 JBrowse link
G Kmt2d lysine methyltransferase 2D ISO mRNA:decreased expression:breast (human) RGD PMID:23754336 RGD:9588236 NCBI chr 7:129,980,744...130,022,088 JBrowse link
G Kmt2e lysine methyltransferase 2E ISO mRNA:decreased expression:breast (human) RGD PMID:23754336 RGD:9588236 NCBI chr 4:12,550,570...12,655,329 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Breast cancer, somatic ClinVar
OMIM
RGD
PMID:2547513 PMID:3627975 PMID:15696205 PMID:17332249 PMID:21063026 More... RGD:2314909 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Krt81 keratin 81 susceptibility ISO DNA:SNP:3'UTR:rs3660(human) RGD PMID:32678982 RGD:155882455 NCBI chr 7:132,577,112...132,582,238 JBrowse link
G Ksr1 kinase suppressor of ras 1 disease_progression ISO RGD PMID:24909178 RGD:127229932 NCBI chr10:64,459,786...64,596,083 JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 severity ISO mRNA:decreased expression:breast (human) RGD PMID:21837478 RGD:9588606 NCBI chr 3:151,597,903...151,633,657 JBrowse link
G Lep leptin ISO protein:increased expression:serum RGD PMID:16019138 RGD:8694425 NCBI chr 4:58,626,529...58,640,663 JBrowse link
G Letmd1 LETM1 domain containing 1 ISO protein:increased expression:breast RGD PMID:19208263 RGD:2314917 NCBI chr 7:131,584,241...131,597,797 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor severity
onset
ISO RGD PMID:17692113 PMID:12679452 PMID:17709176 RGD:2292541, RGD:2292545, RGD:2292539 NCBI chr 6:5,661,871...5,728,109 JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO protein:increased expression:breast RGD PMID:10508127 RGD:2314923 NCBI chr 1:66,931,712...67,027,610 JBrowse link
G Lrrc41 leucine rich repeat containing 41 ISO ClinVar Annotator: match by term: RAD54L-related condition ClinVar PMID:25741868 NCBI chr 5:129,554,547...129,575,450 JBrowse link
G Lsp1 lymphocyte-specific protein 1 susceptibility ISO DNA:SNP:intron:rs3817198T>C(human)
DNA:SNPs: :rs569550,rs592373(human)
RGD PMID:21127985 PMID:26191300 RGD:407571686, RGD:11063875 NCBI chr 1:197,614,677...197,648,414 JBrowse link
G Lta lymphotoxin alpha susceptibility ISO DNA:polymorphism, haplotype: :252A>G (human)
DNA:SNP:intron
RGD PMID:18409070 PMID:11841482 RGD:8548786, RGD:8548791 NCBI chr20:3,622,291...3,625,852 JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor susceptibility ISO RGD PMID:8971156 RGD:1599219 NCBI chr 8:107,500,856...107,551,595 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO RGD PMID:10216485 RGD:2292627 NCBI chr 8:73,578,747...73,650,184 JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO RGD PMID:10216485 RGD:2292627 NCBI chr 7:9,241,449...9,264,216 JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO protein:increased protein:mammary gland RGD PMID:24233520 PMID:12618338 RGD:7495808, RGD:7495809 NCBI chr10:46,107,639...46,128,986 JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 exacerbates ISO mRNA:splice variant:exon 2: (human) RGD PMID:32601196 PMID:21317887 RGD:155230826, RGD:155249848 NCBI chr12:7,389,032...7,398,377 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 disease_progression ISO RGD PMID:17529967 PMID:18036273 PMID:17997823 RGD:2289657, RGD:2293356, RGD:2293357 NCBI chr 2:45,081,889...45,150,555 JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO RGD PMID:10490831 RGD:151356925 NCBI chr17:58,078,175...58,098,455 JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO protein:increased expression, increased phosphorylation:breast RGD PMID:15928662 RGD:2314939 NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk15 mitogen-activated protein kinase 15 disease_progression ISO protein:decreased expression:tumor (human) RGD PMID:12917323 RGD:2304230 NCBI chr 7:109,575,619...109,595,339 JBrowse link
G Mapt microtubule-associated protein tau disease_progression ISO RGD PMID:18668363 RGD:8158093 NCBI chr10:89,638,618...89,736,108 JBrowse link
G Mc1r melanocortin 1 receptor ISO ClinVar Annotator: match by term: Malignant breast neoplasm ClinVar PMID:9302268 PMID:9665397 PMID:10631149 PMID:12876664 PMID:15994880 More... NCBI chr19:68,360,950...68,363,877 JBrowse link
G Mcph1 microcephalin 1 severity ISO DNA:silent mutation, missense mutation:cds:p.S742, p.A761V (rs2912010, rs1057090) (human) RGD PMID:23296058 RGD:9589038 NCBI chr16:71,021,855...71,224,067 JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased expression:breast tumor (rat) RGD PMID:15844214 RGD:2293626 NCBI chr 7:55,176,558...55,201,757 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISS OMIM:114480 MouseDO NCBI chr 4:46,756,823...46,864,041 JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility
severity
ISO DNA:polymorphisms:cds:p.L84F, p.I143V (human)
protein:decreased expression:tumor (human)
RGD PMID:16014702 PMID:15741301 RGD:2317675, RGD:2317691 NCBI chr 1:201,140,832...201,367,481 JBrowse link
G Mier3 MIER family member 3 disease_progression
exacerbates
ISO RGD PMID:34242623 PMID:34242623 RGD:407571690, RGD:407571690 NCBI chr 2:43,287,546...43,316,422 JBrowse link
G Mir143 microRNA 143 ISO RNA:decreased expression:peripheral blood mononuclear cell (human) RGD PMID:32104069 RGD:153297766 NCBI chr18:55,101,006...55,101,110 JBrowse link
G Mir145 microRNA 145 ISO RNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:32104069 RGD:153297766 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir152 microRNA 152 ISO miRNA:increased expression:plasma RGD PMID:26958084 RGD:21066332 NCBI chr10:81,832,936...81,833,020 JBrowse link
G Mir21 microRNA 21 severity IEP
ISO
RNA:increased expression:thoracic lymph node
RNA:increased expression:peripheral blood mononuclear cell (human)
miRNA:increased expression:breast (human)
RNA:increased expression:blood serum (human)
RGD PMID:18812439 PMID:32157513 PMID:32104069 PMID:22638884 RGD:152998878, RGD:152025189, RGD:153297766, RGD:152998900 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir221 microRNA 221 IEP RNA:increased expression:serum, thoracic lymph node,breast RGD PMID:32157513 RGD:152025189 NCBI chr  X:6,023,182...6,023,290 JBrowse link
G Mir222 microRNA 222 IEP RNA:increased expression:breast RGD PMID:32157513 RGD:152025189 NCBI chr  X:6,022,621...6,022,723 JBrowse link
G Mir31 microRNA 31 ISO RNA:decreased expression:peripheral blood mononuclear cell (human) RGD PMID:32104069 RGD:153297766 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir429 microRNA 429 IEP RNA:increased expression:serum, thoracic lymph node, breast RGD PMID:32157513 RGD:152025189 NCBI chr 5:171,929,682...171,929,766 JBrowse link
G Mir494 microRNA 494 ISO RNA:decreased expression:breast RGD PMID:28055013 RGD:156430322 NCBI chr 6:128,728,710...128,728,792 JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO RGD PMID:22004841 PMID:21880954 RGD:6483516, RGD:6483528 NCBI chr 1:199,926,150...199,952,847 JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar PMID:8809606 PMID:9506527 PMID:9718327 PMID:10446963 PMID:10713887 More... NCBI chr 8:120,074,871...120,112,109 JBrowse link
G Mlh3 mutL homolog 3 ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:104,881,483...104,917,686 JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility
disease_progression
ISO DNA:insertion:promoter:g.-1607insG (human)
protein:decreased expression:plasma
protein:increased expression:breast, stromal cell (human)
RGD PMID:12473595 PMID:18366705 PMID:21835023 RGD:7207138, RGD:2298552, RGD:7207143 NCBI chr 8:12,943,453...12,963,966 JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:17058024 RGD:8693321 NCBI chr 8:12,925,267...12,938,828 JBrowse link
G Mmp8 matrix metallopeptidase 8 disease_progression ISO RGD PMID:17974962 PMID:18366705 RGD:2298553, RGD:2298552 NCBI chr 8:4,724,009...4,733,864 JBrowse link
G Msh2 mutS homolog 2 susceptibility ISO DNA:polymorphism:cds:p.G322D
ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar
RGD
PMID:8613431 PMID:8700523 PMID:9259192 PMID:9718327 PMID:10080150 More... RGD:2293512 NCBI chr 6:12,567,368...12,626,534 JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Breast cancer, susceptibility to | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar Annotator: match by term: Breast cancer, somatic | ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
ClinVar PMID:2968408 PMID:10508506 PMID:10537275 PMID:11153917 PMID:11586295 More... NCBI chr 6:12,316,190...12,333,505 JBrowse link
G Muc1 mucin 1, cell surface associated ISO RGD PMID:8869094 RGD:7349378 NCBI chr 2:176,933,312...176,938,497 JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: Malignant tumor of breast ClinVar PMID:16557584 PMID:21195604 PMID:25741868 PMID:26467025 PMID:26900293 More... NCBI chr 5:130,274,034...130,286,149 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor severity ISO
ISS
IEP
DNA:amplification:exon (human)
OMIM:114480
protein:increased expression:mammary gland (rat)
MouseDO
RGD
PMID:10706127 PMID:22614519 RGD:7207838, RGD:7241002 NCBI chr 7:95,483,105...95,488,031 JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor exacerbates ISO RNA:increased expression:breast (human) RGD PMID:26596839 RGD:150524333 NCBI chr 8:127,952,161...127,956,230 JBrowse link
G Nbn nibrin susceptibility
disease_progression
ISO DNA:SNP
ClinVar Annotator: match by term: Malignant breast neoplasm | ClinVar Annotator: match by term: Malignant tumor of breast
protein:decreased expression:breast
DNA:missense mutation:exon:p.I171V
ClinVar
RGD
PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436