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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:breast carcinoma
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Accession:DOID:3459 term browser browse the term
Definition:A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (DO)
Synonyms:exact_synonym: Mammary carcinoma;   breast carcinomas;   carcinoma of breast;   human mammary carcinoma;   human mammary carcinomas
 narrow_synonym: MULTIFOCAL BREAST CARCINOMA
 primary_id: RDO:9001794
 xref: NCI:C124249;   NCI:C4872
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
breast carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 ISO mRNA:increased expression:breast (human) RGD PMID:23556449 RGD:11041882 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 ISO protein:decreased expression:breast RGD PMID:11948115 RGD:2315568 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 ISO protein:increased expression:breast RGD PMID:29882245 RGD:153297792 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Afdn afadin, adherens junction formation factor disease_progression ISO RGD PMID:16819513 RGD:13838725 NCBI chr 1:53,884,711...54,034,216
Ensembl chr 1:53,905,373...54,034,216
JBrowse link
G Amacr alpha-methylacyl-CoA racemase severity ISO RGD PMID:15941950 RGD:2315635 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:8940262 PMID:9288102 PMID:9585599 PMID:9724771 PMID:9731522 More... NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 disease_progression ISO protein:altered localization:cytoplasm RGD PMID:11748448 RGD:2315667 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Atm ATM serine/threonine kinase disease_progression ISO protein:decreased expression:lymph node
ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Multifocal breast carcinoma
ClinVar
RGD
PMID:2557216 PMID:8755918 PMID:9463314 PMID:9536098 PMID:9622061 More... RGD:1643351 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp7b ATPase copper transporting beta severity ISO mRNA,protein:increased expression:breast RGD PMID:11802810 RGD:2292670 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:16199547 PMID:20077502 PMID:21344236 PMID:25741868 PMID:28492532 More... NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bcl2l1 Bcl2-like 1 ISO RGD PMID:16886624 RGD:1643480 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 treatment ISO RGD PMID:22207111 RGD:14392810 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bin1 bridging integrator 1 ISO RGD PMID:10652430 RGD:1580043 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ameliorates ISO mRNA:increased expression:breast (human) RGD PMID:31964418 RGD:153344516 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 exacerbates ISO mRNA:increased expression:breast (human) RGD PMID:31964418 RGD:153344516 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 disease_progression ISO mRNA:increased expression:breast (human) RGD PMID:31964418 RGD:153344516 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
JBrowse link
G Brca1 BRCA1, DNA repair associated disease_progression ISO protein:altered localization:cytoplasm
ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast
ClinVar
RGD
PMID:2144777 PMID:7795652 PMID:7837387 PMID:7894493 PMID:7939630 More... RGD:2293150 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:8589730 PMID:8665505 PMID:8673089 PMID:8706004 PMID:8988179 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brip1 BRCA1 interacting helicase 1 ISO mRNA:increased expression:breast (human)
ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast
ClinVar
RGD
PMID:12872252 PMID:16116423 PMID:17033622 PMID:18628483 PMID:19935797 More... RGD:11251773 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar NCBI chr 1:205,731,814...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G C8h11orf65 similar to human chromosome 11 open reading frame 65 ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Multifocal breast carcinoma ClinVar PMID:2557216 PMID:9536098 PMID:9622061 PMID:9887333 PMID:10330348 More... NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748
JBrowse link
G Cadm1 cell adhesion molecule 1 severity ISO DNA:hypermethylation RGD PMID:17260099 RGD:2289088 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Car9 carbonic anhydrase 9 disease_progression ISO RGD PMID:17245699 RGD:2293195 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp3 caspase 3 disease_progression ISO protein:increased expression:breast RGD PMID:12107344 RGD:2293309 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cav1 caveolin 1 ISO protein:increased expression:breast
DNA:missense mutation: :p.P132L (human)
RGD PMID:17915016 PMID:11289096 RGD:2289101, RGD:8661775 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx7 chromobox 7 severity ISO protein:decreased expression:breast (human) RGD PMID:21779448 RGD:11352698 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cd46 CD46 molecule disease_progression ISO RGD PMID:7532466 PMID:15378282 RGD:2293551, RGD:2293547 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cd59 CD59 molecule disease_progression ISO RGD PMID:12898600 RGD:2326192 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cd82 Cd82 molecule ISO protein:decreased expression:breast RGD PMID:15958618 RGD:2289398 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
JBrowse link
G Cd9 CD9 molecule disease_progression ISO RGD PMID:16132579 RGD:2326200 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdc25a cell division cycle 25A disease_progression ISO RGD PMID:19555767 RGD:2734052 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B disease_progression ISO RGD PMID:15550849 RGD:4105449 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdh1 cadherin 1 ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:25741868 PMID:28492532 PMID:29805042 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation:promoter RGD PMID:11389090 RGD:2293545 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO DNA:amplification RGD PMID:9916925 RGD:2293583 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:9536098 PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 More... NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Crp C-reactive protein severity ISO RGD PMID:14648971 RGD:9585643 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Ctcf CCCTC-binding factor ISO protein:altered expression:breast tumor (human) RGD PMID:15354217 RGD:151356910 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 susceptibility ISO DNA:polymorphism (human) RGD PMID:15978329 RGD:2317609 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ISO mRNA:decreased expression:breast (human) RGD PMID:16180015 RGD:151361183 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Dcn decorin ISO RGD PMID:18688028 RGD:2311418 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO DDR1 acts with Syk RGD PMID:21499918 PMID:29483153 RGD:151347448, RGD:151347599 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO DNA:amplification:cds, 3' utr (human) RGD PMID:18413808 PMID:18522728 RGD:2293732, RGD:2293728 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eno2 enolase 2 ISO RGD PMID:16608642 RGD:2293740 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Ep300 E1A binding protein p300 ISO protein:increased expression:breast RGD PMID:12725419 RGD:2289908 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:8797827 PMID:9579555 PMID:20221251 PMID:21228398 PMID:21612988 More... NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Esr1 estrogen receptor 1 severity
disease_progression
ISO mRNA, protein:increased expression:breast
protein:increased serine phosphorylation
RGD PMID:18234277 PMID:15355923 RGD:2290017, RGD:8552986 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fas Fas cell surface death receptor ISO protein:decreased expression:breast RGD PMID:15792116 RGD:2290130 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo11 F-box protein 11 ameliorates ISO human constructs and cell line in a mouse model RGD PMID:25203322 RGD:152025262 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:8532703 RGD:8655550 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Foxa1 forkhead box A1 ameliorates ISO RGD PMID:27524420 RGD:151665821 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Fzd1 frizzled class receptor 1 ISO RGD PMID:15492823 RGD:2298699 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Fzd2 frizzled class receptor 2 ISO protein:increased expression:breast RGD PMID:15492823 RGD:2298699 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Gng3 G protein subunit gamma 3 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603
JBrowse link
G Hdac1 histone deacetylase 1 ISO RGD PMID:16172792 RGD:2306216 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hnf1a HNF1 homeobox A ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:24033266 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO protein:increased expression:serum,urine: RGD PMID:29940770 RGD:14985218 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Kdm6b lysine demethylase 6B ISO mRNA:increased expression:breast (human) RGD PMID:23152497 RGD:9587818 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kdr kinase insert domain receptor no_association
severity
ISO RGD PMID:15753992 PMID:12378509 RGD:2291952, RGD:2291950 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Klk6 kallikrein related-peptidase 6 ISO RGD PMID:18992199 RGD:2314863 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
JBrowse link
G Kmt2d lysine methyltransferase 2D ISO protein:increased expression:cytoplasm, breast RGD PMID:20433758 RGD:150523761 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 ISO mRNA, protein:decreased exoression:breast, tumor (human) RGD PMID:18686028 RGD:151893465 NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 ISO protein:decreased expression:breast (human) RGD PMID:17546051 RGD:9589053 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:21774103 PMID:21970370 PMID:25741868 PMID:28259294 PMID:28492532 More... NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:15713769 PMID:16083711 PMID:17510385 PMID:20533529 PMID:21404117 More... NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mlh3 mutL homolog 3 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:25741868 NCBI chr 6:104,881,483...104,917,686
Ensembl chr 6:104,881,483...104,917,728
JBrowse link
G Mmp14 matrix metallopeptidase 14 disease_progression ISO RGD PMID:9158005 RGD:2314951 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO protein:decreased expression:tumor (human)
ClinVar Annotator: match by term: Breast carcinoma
DNA:polymorphisms:intron, exon:multiple (human)
ClinVar
RGD
PMID:23080121 PMID:23912341 PMID:28492532 PMID:14511253 PMID:19383352 RGD:2300250, RGD:2317721 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Msh2 mutS homolog 2 disease_progression
severity
ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast
protein:decreased expression:breast
ClinVar
RGD
PMID:6096739 PMID:8062247 PMID:8566964 PMID:8872463 PMID:8895729 More... RGD:2293524, RGD:2293507, RGD:2293505 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Carcinoma of breast
ClinVar Annotator: match by term: Breast carcinoma
ClinVar PMID:8838326 PMID:10537275 PMID:10699937 PMID:11470537 PMID:12019211 More... NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 ISO mRNA, protein:decreased expression:breast carcinoma (human) RGD PMID:19794912 RGD:2317017 NCBI chr16:51,202,497...51,347,791
Ensembl chr16:51,253,562...51,347,793
JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:11818965 PMID:12606733 PMID:12917422 PMID:15931596 PMID:15987719 More... NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ameliorates
treatment
ISO mouse cell line in a mouse model RGD PMID:22088941 PMID:20823152 RGD:150519914, RGD:150520170 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 disease_progression ISO mRNA:decreased expression:breast (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542
JBrowse link
G Nbn nibrin ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:9590180 PMID:9620777 PMID:10398434 PMID:10852373 PMID:11093281 More... NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 severity ISO RGD PMID:17902051 RGD:2293529 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 severity ISO protein:increased expression:breast (human) RGD PMID:12725419 RGD:2289908 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO RGD PMID:9036878 RGD:2299061 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 disease_progression ISO DNA:SNP: :rs1143684 (human) RGD PMID:21351093 RGD:11073689 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:18302019 PMID:18987736 More... NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Parl presenilin associated, rhomboid-like severity ISO mRNA:increased expression:breast (human) RGD PMID:24185965 RGD:12902629 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha disease_progression ISO protein:increased expression:breast RGD PMID:16741576 RGD:2292178 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta disease_progression ISO protein:increased expression:breast RGD PMID:16741576 RGD:2292178 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO protein:increased expression:breast RGD PMID:1683701 RGD:2299875 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plk1 polo-like kinase 1 severity ISO protein:increased expression:breast RGD PMID:15785925 RGD:2299942 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk3 polo-like kinase 3 disease_progression ISO protein:increased expression:breast RGD PMID:15785925 RGD:2299942 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:25741868 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Prc1 protein regulator of cytokinesis 1 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prss8 serine protease 8 ISO RGD PMID:11774283 RGD:2292485 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP protein:altered expression:tumor (rat) RGD PMID:21889127 RGD:9854639 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Ptch1 patched 1 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:28492532 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:19409520 PMID:25741868 PMID:26023681 PMID:28492532 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rad51c RAD51 paralog C ISO ClinVar Annotator: match by term: Breast carcinoma | ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:20400964 PMID:21990120 PMID:22538716 PMID:22725699 PMID:23117857 More... NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
JBrowse link
G Rad51d RAD51 paralog D ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:21822267 PMID:25741868 PMID:26720727 PMID:26720728 PMID:28492532 More... NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Ret ret proto-oncogene ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:17007568 RGD:2298868 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO protein:increased expression:tumor (human) RGD PMID:21556566 RGD:5133696 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO RGD PMID:15382064 RGD:2306233 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Smad2 SMAD family member 2 disease_progression ISO RGD PMID:11809701 RGD:2300007 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Snw1 SNW domain containing 1 severity ISO protein:increased expression:breast (human) RGD PMID:24150787 RGD:11035252 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO protein:increased expression:breast RGD PMID:29882245 RGD:153297792 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO mRNA:increased expression:breast RGD PMID:15212687 RGD:2302558 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 ISO mRNA:increased expression:breast RGD PMID:15212687 RGD:2302558 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Stat1 signal transducer and activator of transcription 1 disease_progression ISO protein:increased activity:breast RGD PMID:12374673 RGD:2291894 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stk11 serine/threonine kinase 11 ISO protein:decreased expression:breast
ClinVar Annotator: match by term: Breast carcinoma
ClinVar
RGD
PMID:16287113 PMID:17676035 PMID:24033266 PMID:25186627 PMID:25452441 More... RGD:2291945 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Terc telomerase RNA component disease_progression ISO RNA:increased expression:breast RGD PMID:16841302 PMID:12237877 RGD:2291965, RGD:2291971 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:15814878 PMID:17460043 PMID:18753630 PMID:18931339 PMID:19147845 More... NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfrc transferrin receptor ISO RGD PMID:11497259 RGD:2292020 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Thoc5 THO complex 5 ISO DNA:missense mutations:cds:c.1139C>A, c.1495G>A (human) RGD PMID:16959974 RGD:2317225 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
G Thrb thyroid hormone receptor beta ISO DNA:loss of heterozygosity (human) RGD PMID:2573734 RGD:2315100 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 disease_progression ISO associated with Tumor Virus Infections;DNA:hypermethylation:promoter
protein:decreased expression:breast
RGD PMID:18205041 PMID:17032447 RGD:2290409, RGD:2290413 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Carcinoma of breast ClinVar PMID:1565143 PMID:1591732 PMID:1683921 PMID:2046748 PMID:4122735 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsg101 tumor susceptibility 101 susceptibility ISO DNA:deletions RGD PMID:9019400 RGD:1600429 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Twist1 twist family bHLH transcription factor 1 exacerbates ISO RGD PMID:27524420 RGD:151665821 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Vegfc vascular endothelial growth factor C ISO RGD PMID:19382240 RGD:2315477 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Wnt2 Wnt family member 2 disease_progression ISO DNA:amplification:breast RGD PMID:7903963 RGD:2291879 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Xiap X-linked inhibitor of apoptosis exacerbates ISO mRNA:increased expression:breast (human) RGD PMID:31964418 RGD:153344516 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 ISO ClinVar Annotator: match by term: Breast carcinoma ClinVar PMID:25330149 PMID:25452441 PMID:26681312 PMID:26845104 PMID:28492532 More... NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
G Zfhx3 zinc finger homeobox 3 disease_progression ISO RGD PMID:15671546 RGD:2315696 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771
JBrowse link
bilateral breast cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Bilateral breast carcinoma ClinVar PMID:19781682 PMID:25741868 PMID:26689913 PMID:26787654 PMID:28492532 More... NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:9150151 PMID:11376024 PMID:16683254 PMID:19491284 PMID:20104584 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Mc1r melanocortin 1 receptor ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:23047549 PMID:23621914 PMID:25741868 PMID:26467025 PMID:26689913 More... NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:20852946 PMID:22692731 PMID:24448499 PMID:24556926 PMID:25186627 More... NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:17102082 PMID:19351833 PMID:20208144 PMID:21520333 PMID:23175444 More... NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO ClinVar Annotator: match by term: bilateral breast cancer ClinVar PMID:28492532 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
breast adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Brca1 BRCA1, DNA repair associated treatment ISO RGD PMID:8589721 RGD:126925966 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Cat catalase ISO RGD PMID:25050522 RGD:9226881 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccne1 cyclin E1 ISO DNA:amplification RGD PMID:18089785 RGD:2289225 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccng1 cyclin G1 ISO mRNA, protein:altered expression:mammary (mouse) RGD PMID:11146550 RGD:2315939 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEP mRNA:increased expression:mammary epithelium (rat) RGD PMID:11097088 RGD:7829735 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 no_association ISO RGD PMID:11466624 RGD:2289868 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO mRNA:increased expression:breast RGD PMID:9811352 RGD:2306185 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:12460918 More... NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ksr1 kinase suppressor of ras 1 severity ISO RGD PMID:24909178 RGD:127229932 NCBI chr10:63,961,771...64,098,076
Ensembl chr10:63,961,759...64,098,076
JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA,protein:increased expression:breast RGD PMID:7678777 RGD:2324855 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein IAGP RGD PMID:10849326 RGD:1298988 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:12068296 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Slc22a18 solute carrier family 22, member 18 ISO ClinVar Annotator: match by term: Breast adenocarcinoma ClinVar PMID:9520460 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975
JBrowse link
G Tnf tumor necrosis factor ISO human protein in a rat model RGD PMID:12536235 RGD:14995452 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Breast adenocarcinoma, somatic ClinVar
RGD
PMID:1673792 PMID:1686725 PMID:7881428 PMID:8364550 PMID:10713666 More... RGD:2315939 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
breast carcinoma in situ term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf2r insulin-like growth factor 2 receptor ISO DNA:loss of heterozygosity RGD PMID:8649861 RGD:2311631 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
breast ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amfr autocrine motility factor receptor ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member ISO RGD PMID:11605729 RGD:1579979 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar PMID:9063749 PMID:10196379 PMID:11400546 PMID:14555511 PMID:15235020 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar PMID:11062481 PMID:11927503 PMID:14555511 PMID:15235023 PMID:17767707 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Bsg basigin (Ok blood group) ISO mRNA:increased expression:breast RGD PMID:9154157 RGD:2289059 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar PMID:26467025 PMID:27148582 PMID:28492532 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Ccdc180 coiled-coil domain containing 180 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
JBrowse link
G Ccdc71l coiled-coil domain containing 71-like ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 6:48,959,913...48,964,112
Ensembl chr 6:48,960,191...48,960,841
JBrowse link
G Cd44 CD44 molecule (Indian blood group) disease_progression ISO mRNA, protein:splice variant, increased expression:breast RGD PMID:16425351 RGD:2289356 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cnnm1 cyclin and CBS domain divalent metal cation transport mediator 1 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:242,296,367...242,354,908
Ensembl chr 1:242,296,422...242,353,513
JBrowse link
G Coro6 coronin 6 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
JBrowse link
G Cpamd8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 4:155,332,827...155,413,098
Ensembl chr 4:155,332,827...155,413,117
JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220
JBrowse link
G Creb3 cAMP responsive element binding protein 3 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 5:57,817,835...57,823,171
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 severity ISO protein:increased expression:breast RGD PMID:12054692 RGD:2298489 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Fubp1 far upstream element binding protein 1 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362
JBrowse link
G Lrat lecithin retinol acyltransferase ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:166,345,853...166,471,715
NCBI chr 1:166,491,721...166,530,575
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Nts neurotensin ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Phf24 PHD finger protein 24 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 5:57,143,428...57,171,054
Ensembl chr 5:57,142,632...57,168,497
JBrowse link
G Plk4 polo-like kinase 4 ISO protein:increased expression:breast RGD PMID:26439168 RGD:11075990 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pml PML nuclear body scaffold ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Rad54l RAD54 like ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar PMID:10362365 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO associated with lymphatic metastasis; protein:increased expression:breast tumor, lymph node (human) RGD PMID:20978191 RGD:152995469 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rnf212 ring finger protein 212 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr14:949,397...988,377
Ensembl chr14:949,448...987,831
JBrowse link
G Rp1 RP1, axonemal microtubule associated ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 5:15,121,104...15,582,363
Ensembl chr 5:15,121,133...15,579,363
JBrowse link
G Rrp1 ribosomal RNA processing 1 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr20:10,260,892...10,272,141
Ensembl chr20:10,260,870...10,272,144
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 disease_progression ISO protein:decreased expression:breast (human) RGD PMID:17760952 RGD:152995410 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393
JBrowse link
G Spen spen family transcriptional repressor ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811
JBrowse link
G Syt6 synaptotagmin 6 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b ISO mRNA:decreased expression:breast RGD PMID:17011986 RGD:2290492 NCBI chr15:44,839,818...44,867,582
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tp73 tumor protein p73 ISO mRNA:decreased expression:breast RGD PMID:17011986 RGD:2290492 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tspan8 tetraspanin 8 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
JBrowse link
G Tspear thrombospondin-type laminin G domain and EAR repeats ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr20:10,771,806...10,837,419
Ensembl chr20:10,772,219...10,943,914
JBrowse link
G Xiap X-linked inhibitor of apoptosis severity ISO RGD PMID:17350670 RGD:2315853 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Yeats2 YEATS domain containing 2 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr11:80,743,134...80,829,253
Ensembl chr11:80,743,134...80,829,208
JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 9:64,672,974...64,748,446
Ensembl chr 9:64,709,880...64,744,265
JBrowse link
G Zfp420 zinc finger protein 420 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:85,092,810...85,143,682
Ensembl chr 1:85,093,085...85,106,693
Ensembl chr 1:85,093,085...85,106,693
JBrowse link
G Zfp473 zinc finger protein 473 ISO ClinVar Annotator: match by term: Ductal breast carcinoma ClinVar NCBI chr 1:95,222,683...95,243,328
Ensembl chr 1:95,223,433...95,243,325
JBrowse link
breast lobular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:8389152 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8389152 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast lobular carcinoma
CTD
ClinVar
PMID:8557030 PMID:15235021 PMID:17660459 PMID:20373070 PMID:24763289 More... NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Myh9 myosin, heavy chain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28650484 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Ppp1r12b protein phosphatase 1, regulatory subunit 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28650484 NCBI chr13:46,199,418...46,397,108
Ensembl chr13:46,201,251...46,397,108
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15609129 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28650484 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432
JBrowse link
breast metaplastic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn6 cellular communication network factor 6 ISS MouseDO NCBI chr20:42,569,309...42,585,126
Ensembl chr20:42,569,309...42,585,126
JBrowse link
ductal carcinoma in situ term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO protein:increased expression:myoepithelial cells: RGD PMID:16735089 RGD:10053629 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Ang angiogenin ISO protein:increased expression:breast RGD PMID:15776477 RGD:2325702 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Anxa1 annexin A1 ISO protein:decreased expression:mammary gland RGD PMID:22323911 RGD:7421537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Ar androgen receptor ISO RGD PMID:17543076 RGD:1643341 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin ISO protein:increased expression:breast RGD PMID:8543395 RGD:2292664 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Bcl2 BCL2, apoptosis regulator disease_progression ISO RGD PMID:12628841 RGD:2289659 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO protein:increased expression:breast RGD PMID:16421596 RGD:2293106 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bnip3 BCL2 interacting protein 3 ISO RGD PMID:14648660 RGD:7483575 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brca1 BRCA1, DNA repair associated treatment IEP RGD PMID:25861310 RGD:127284854 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated onset
treatment
ISO
IEP
DNA:missense mutation: :5972C>T RGD PMID:16280055 PMID:25861310 RGD:2289048, RGD:127284854 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Car9 carbonic anhydrase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20526721 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp6 caspase 6 ISO protein:increased expression:breast RGD PMID:10574243 RGD:2301339 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Ccnd1 cyclin D1 ISO protein:decreased expression:breast RGD PMID:14612904 RGD:2289132 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 ISO DNA:hypermethylation:promoter, breast RGD PMID:14601057 RGD:2289156 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO protein:increased expression:breast RGD PMID:12628841 RGD:2289659 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO protein:increased expression:breast RGD PMID:15788662 PMID:17119686 RGD:2289981, RGD:2289931 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:9470844 RGD:2289952 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:15788662 RGD:2289981 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO associated with Carcinoma, Ductal, Breast RGD PMID:15841074 RGD:2289965 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit ISO mRNA, protein:increased expression:breast RGD PMID:17254320 RGD:2293756 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO protein:altered localization:nucleus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20526721 PMID:16080559 RGD:2306227 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hoxb13 homeo box B13 ISO DNA:hypermethylation RGD PMID:19250546 RGD:2314726 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Klk10 kallikrein related-peptidase 10 disease_progression ISO mRNA:decreased expression:breast RGD PMID:12788170 RGD:2314849 NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376
JBrowse link
G Ldhb lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23437403 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO protein:increased expression:breast RGD PMID:17642161 RGD:2290392 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:breast RGD PMID:14744773 RGD:2290436 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Notch4 notch receptor 4 ISO RGD PMID:17440163 RGD:2299156 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 ISO RGD PMID:22886747 RGD:7775026 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pgr progesterone receptor disease_progression ISO RGD PMID:12628841 RGD:2289659 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Prkca protein kinase C, alpha ISO protein:decreased expression:breast RGD PMID:15454252 RGD:2292458 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Ptges prostaglandin E synthase ISO protein:increased expression:breast RGD PMID:16353170 RGD:2300083 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression ISO mRNA, protein:decreased expression:breast RGD PMID:18199541 PMID:18237383 RGD:2300203, RGD:2300199 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO protein:increased expression:breast RGD PMID:15564794 RGD:2292561 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO mRNA, protein:decreased expression:breast RGD PMID:15312366 RGD:2299890 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO DNA:amplification RGD PMID:17375183 RGD:2298754 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20526721 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO protein:increased activity:breast RGD PMID:17060931 RGD:2315078 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:breast RGD PMID:17163404 RGD:2315089 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO protein:altered localization:nucleus
CTD Direct Evidence: marker/mechanism
protein:decreased expression:breast
CTD
RGD
PMID:15609129 PMID:15609129 PMID:16133357 RGD:2291932, RGD:2291930 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA:decreased expression:breast RGD PMID:15010825 RGD:2291992 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tff1 trefoil factor 1 ISO RGD PMID:15375487 RGD:2292005 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO protein:increased expression:breast RGD PMID:14744773 RGD:2290436 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO protein:increased expression:breast RGD PMID:14744773 RGD:2290436 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Top2a DNA topoisomerase II alpha severity ISO protein:increased expression:breast RGD PMID:11070118 RGD:2315133 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53 tumor protein p53 ISO protein:increased expression:breast
ClinVar Annotator: match by term: Ductal carcinoma in situ
ClinVar
RGD
PMID:1565143 PMID:1683921 PMID:7887414 PMID:8062826 PMID:9242456 More... RGD:2289931 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tymp thymidine phosphorylase ISO RGD PMID:9306962 RGD:2293726 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:breast RGD PMID:19623180 RGD:2315458 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
Ehrlich tumor carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule treatment IDA RGD PMID:19269163 RGD:11352683 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand treatment IDA RGD PMID:19269163 RGD:11352683 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Ceacam20 CEA cell adhesion molecule 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34605108 NCBI chr 1:79,622,077...79,643,782
Ensembl chr 1:79,622,077...79,643,782
JBrowse link
invasive ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A disease_progression ISO RGD PMID:19879256 RGD:2315549 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 disease_progression ISO DNA:hypermethylation:CpG island RGD PMID:19549921 RGD:153298911 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 disease_progression ISO RGD PMID:25376607 RGD:13831358 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:breast RGD PMID:22366088 RGD:8695990 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO DNA:missense mutation:p.E17K (human) RGD PMID:18392055 RGD:13209138 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:18776816 PMID:19171478 RGD:7421535, RGD:7421560 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 treatment ISO RGD PMID:19171478 RGD:7421560 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ar androgen receptor severity ISO RGD PMID:16075292 RGD:1643344 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin ISO RGD PMID:11523048 RGD:2292660 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO protein:increased expression:breast (human) RGD PMID:21136934 RGD:11049179 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Atf4 activating transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14604972 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Aurka aurora kinase A ISO protein:altered expression RGD PMID:14693746 RGD:1643348 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bag1 BAG cochaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19066611 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast ClinVar PMID:7493024 PMID:11179017 PMID:11956590 PMID:12698193 PMID:12955716 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast ClinVar PMID:14973102 PMID:15145354 PMID:17899372 PMID:18627636 PMID:18779604 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator disease_progression ISO RGD PMID:15592684 RGD:2289400 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Cav1 caveolin 1 no_association ISO DNA:missense mutation: :p.P132L (human) RGD PMID:21909981 RGD:8661779 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased expression:breast, ductal carcinoma (human) RGD PMID:18790652 RGD:4891911 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnd3 cyclin D3 severity ISO protein:increased expression:breast RGD PMID:11329139 RGD:2316016 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Cd44 CD44 molecule (Indian blood group) disease_progression ISO protein:increased expression:breast RGD PMID:17059779 RGD:2289352 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8557030 PMID:17660459 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:hypermethylation:promoter:breast, serum RGD PMID:17383681 RGD:2289677 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 ISO DNA:hypermethylation:promoter:breast, serum RGD PMID:17383681 RGD:2289677
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 ISO DNA:hypermethylation:promoter:breast, serum RGD PMID:17383681 RGD:2289677
G Cldn4 claudin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19142967 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clu clusterin ISO RGD PMID:10934144 RGD:8699513 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein disease_progression ISO protein:increased expression:breast RGD PMID:23686806 RGD:7488897 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Csnk1e casein kinase 1, epsilon ISO DNA:mutation:CDS:multiple nonsynonymous mutations (human) RGD PMID:14871824 RGD:2306813 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 ISO DNA:mutation:CDS:multiple nonsynonymous mutations (human) RGD PMID:14871824 RGD:2306813 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 ISO mRNA, protein:increased expression:breast RGD PMID:11742495 RGD:2289858 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28235801 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:14532106 RGD:9588325 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 ISO protein:increased expression:breast (human) RGD PMID:19141649 RGD:11554027 NCBI chr  X:20,023,746...20,066,730
Ensembl chr  X:20,023,746...20,066,566
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO RGD PMID:12231533 RGD:2289894 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Foxc1 forkhead box C1 disease_progression ISO RGD PMID:21424368 RGD:8662363 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO protein:altered localization:nucleus RGD PMID:16080559 RGD:2306227 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hoxb7 homeo box B7 ISO mRNA:increased expression:breast epithelium (human) RGD PMID:17018609 RGD:10402178 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 severity ISO protein:decreased expression:ductal breast carcinoma (human) RGD PMID:10682658 RGD:4890946 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:breast RGD PMID:22135852 RGD:8549515 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:breast RGD PMID:21263407 RGD:8655888 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Inha inhibin subunit alpha ISO RGD PMID:15583806 RGD:2290390 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Jup junction plakoglobin disease_progression ISO RGD PMID:16610682 RGD:2291882 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor disease_progression ISO RGD PMID:15592684 RGD:2289400 NCBI chr13:44,774,823...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase severity ISO RGD PMID:16721362 RGD:2292426 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 disease_progression ISO RGD PMID:15592684 RGD:2289400 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity ISO protein:increased expression:tumor (human) RGD PMID:10590366 RGD:2317607 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression ISO RGD PMID:11585740 RGD:2293606 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 ISO protein:decreased expression:breast RGD PMID:11561770 RGD:2293536 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Nefl neurofilament light chain ISO DNA:loss of heterozygosity RGD PMID:8814452 RGD:2298999 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO mRNA,protein:increased expression:breast: RGD PMID:20802235 RGD:150520014 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Pcna proliferating cell nuclear antigen severity ISO RGD PMID:8102204 RGD:2315014 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Prkci protein kinase C, iota disease_progression ISO protein:increased expression, altered localization:breast, cytoplasm RGD PMID:18538170 RGD:2314932 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Ptger1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751431 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21153458 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO RGD PMID:14511253 RGD:2300250 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Runx3 RUNX family transcription factor 3 disease_progression ISO DNA, protein:hypermethylation, altered localization:promoter RGD PMID:18256927 RGD:2302557 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Serpinb5 serpin family B member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19944674 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28235801 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Smad4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20565773 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23964924 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 disease_progression IEP RGD PMID:17054309 RGD:2291958 NCBI chr 7:130,512,428...130,543,637
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ISO DNA:mutation:CDS:multiple nonsynonymous mutations RGD PMID:14871824 RGD:2306813 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
G Vegfc vascular endothelial growth factor C disease_progression ISO RGD PMID:19885590 RGD:2315471 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Wif1 Wnt inhibitory factor 1 ISO protein:decreased expression:breast RGD PMID:14517837 RGD:727214 NCBI chr 7:56,548,058...56,618,364
Ensembl chr 7:56,548,053...56,618,360
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:polymorphism: :p.R399Q RGD PMID:18752184 RGD:2302569 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
invasive lobular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Invasive lobular breast carcinoma ClinVar PMID:14973102 PMID:25741868 PMID:27257965 PMID:28222693 PMID:28492532 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:breast
DNA:amplification:cds (human)
RGD PMID:12203362 PMID:12448002 RGD:2289133, RGD:11353788 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 ISO DNA:hypermethylation:promoter, breast RGD PMID:14601057 RGD:2289156 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO mRNA, protein:splice variants, altered localization:breast RGD PMID:11245336 RGD:2289362 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 ISO DNA:nonsense mutation: :517insA (human) RGD PMID:17660459 PMID:18213475 RGD:2289492, RGD:2289450 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ctnna1 catenin alpha 1 ISO protein:decreased expression:breast RGD PMID:12047765 RGD:2289795 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 ISO protein:decreased expression:breast RGD PMID:17721269 RGD:2289814 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 severity ISO RGD PMID:16761510 RGD:2289935 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Faslg Fas ligand ISO protein:increased expression:breast RGD PMID:10640988 RGD:2290134 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO protein:altered localization:nucleus RGD PMID:15609129 RGD:2291932 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
male breast carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Male breast carcinoma ClinVar PMID:9654203 PMID:10464631 PMID:17924331 PMID:21952622 PMID:21990134 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
mammary Paget's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO DNA:amplification RGD PMID:16932067 RGD:2289933 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
sporadic breast cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 no_association ISO DNA:hypermethylation:promoter
DNA:repeat:promoter
RGD PMID:17932744 PMID:17904846 RGD:2290043, RGD:8552977 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Mlh1 mutL homolog 1 ISO DNA, protein:hypermethylation, decreased expression:promoter, breast RGD PMID:12173039 RGD:2293522 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association ISO DNA:missense mutations:cds:g.677C>T, g.1298A>T (human) RGD PMID:28330681 RGD:38501055 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Phb1 prohibitin 1 ISO DNA:loss of heterozygosity, mutations: :multiple RGD PMID:1540973 RGD:2292408 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Pten phosphatase and tensin homolog ISO DNA:hypermethylation:promoter: (human) RGD PMID:15287024 RGD:12859037 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18162
    disease of cellular proliferation 7339
      Neoplasms by Site 6969
        Breast Neoplasms 1350
          breast cancer 700
            breast carcinoma 292
              Ehrlich tumor carcinoma 3
              bilateral breast cancer + 8
              breast adenocarcinoma + 18
              breast adenoid cystic carcinoma 0
              breast carcinoma in situ + 51
              breast ductal carcinoma + 110
              breast large cell neuroendocrine carcinoma 0
              breast lobular carcinoma + 15
              breast metaplastic carcinoma + 1
              breast myoepithelial carcinoma 0
              breast papillary carcinoma 0
              breast scirrhous carcinoma 0
              cribriform carcinoma 0
              female breast carcinoma 0
              lipid-rich carcinoma + 0
              luminal breast carcinoma A 0
              luminal breast carcinoma B 0
              male breast carcinoma 1
              nipple carcinoma + 0
              sebaceous breast carcinoma 0
              sporadic breast cancer 5
Path 2
Term Annotations click to browse term
  disease 18162
    disease of anatomical entity 17537
      nervous system disease 13196
        sensory system disease 6412
          skin disease 3782
            breast disease 1360
              Breast Neoplasms 1350
                breast cancer 700
                  breast carcinoma 292
                    Ehrlich tumor carcinoma 3
                    bilateral breast cancer + 8
                    breast adenocarcinoma + 18
                    breast adenoid cystic carcinoma 0
                    breast carcinoma in situ + 51
                    breast ductal carcinoma + 110
                    breast large cell neuroendocrine carcinoma 0
                    breast lobular carcinoma + 15
                    breast metaplastic carcinoma + 1
                    breast myoepithelial carcinoma 0
                    breast papillary carcinoma 0
                    breast scirrhous carcinoma 0
                    cribriform carcinoma 0
                    female breast carcinoma 0
                    lipid-rich carcinoma + 0
                    luminal breast carcinoma A 0
                    luminal breast carcinoma B 0
                    male breast carcinoma 1
                    nipple carcinoma + 0
                    sebaceous breast carcinoma 0
                    sporadic breast cancer 5
paths to the root