Breast Neoplasms - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Breast Neoplasms	go back to main search page
Accession:	DOID:9008939	browse the term
Definition:	Tumors or cancer of the human BREAST.
Synonyms:	exact_synonym:	breast neoplasm; breast tumor; breast tumors; human mammary neoplasm; human mammary neoplasms
	narrow_synonym:	BRIP1-related disorder
	xref:	EFO:0003869; MESH:D001943; MONDO:0021100

show annotations for term's descendants Sort by:
Rat (1550) Mouse (1451) Human (56761) Chinchilla (1312) Bonobo (1406) Dog (1513) Squirrel (1351) Pig (1408) Green Monkey (1389) Naked Mole-rat (1307) All
Genes (1447) QTL (50) Strains (53)

Breast Neoplasms

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 8

CTD Direct Evidence: marker/mechanism

NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988

G

ATP binding cassette subfamily B member 1A

DNA:polymorphism: :3435C>T (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22311042 PMID:19752884

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP-binding cassette, sub-family B member 1B

CTD Direct Evidence: therapeutic

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily G member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

G

acetyl-CoA carboxylase beta

CTD Direct Evidence: marker/mechanism

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

acetylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

actin alpha 2, smooth muscle

CTD Direct Evidence: marker/mechanism

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

activin A receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

G

ADAM metallopeptidase domain 10

CTD Direct Evidence: marker/mechanism

NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889

G

ADAM metallopeptidase domain 33

CTD Direct Evidence: marker/mechanism

NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

adenosine deaminase, RNA-specific

CTD Direct Evidence: marker/mechanism

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

G

adrenoceptor beta 2

GAD

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

alpha-fetoprotein

CTD Direct Evidence: therapeutic

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

advanced glycosylation end product-specific receptor

no_association

DNA:SNPs, insertion/deletion:promoter, :-374T>A, -429T/C (human)
DNA:SNP, haplotype: :rs184003 (human)

RGD

PMID:18058469 PMID:22497255 PMID:24619131

RGD:8695964, RGD:8695989, RGD:8695984

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

anterior gradient 2, protein disulphide isomerase family member

CTD Direct Evidence: marker/mechanism

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

aryl hydrocarbon receptor

CTD Direct Evidence: marker/mechanism

PMID:21515334 PMID:22296396

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

A-kinase anchoring protein 12

CTD Direct Evidence: marker/mechanism

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

AKT serine/threonine kinase 1

susceptibility

protein:increased serine phosphorylation:breast
ClinVar Annotator: match by term: Breast Neoplasms
CTD Direct Evidence: marker/mechanism
DNA:point mutation:cds:p.E17K (human)

ClinVar
CTD
RGD

PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...

RGD:1643330, RGD:2313763, RGD:1643334

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:19075277 PMID:16847462

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

aldolase, fructose-bisphosphate A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

ALK receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast neoplasm

PMID:18724359 PMID:18923523 PMID:18923524 PMID:18923525 PMID:21242967 More...

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

alkB homolog 8, tRNA methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165

G

angiogenin

disease_progression

protein:increased expression:breast

RGD

PMID:9748135 PMID:9539780 PMID:15776477

RGD:2325712, RGD:2325714, RGD:2325702

NCBI chr15:24,312,711...24,323,361

G

angiopoietin-like 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain 34A

CTD Direct Evidence: marker/mechanism

NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116

G

annexin A1

disease_progression

RGD

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

APC regulator of WNT signaling pathway 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310

G

adenine phosphoribosyl transferase

CTD Direct Evidence: marker/mechanism

NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431

G

androgen receptor

CTD Direct Evidence: marker/mechanism

PMID:21633166 PMID:22174584

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

A-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: therapeutic

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

amphiregulin

CTD Direct Evidence: therapeutic

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

ARF GTPase 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

Rho GDP dissociation inhibitor alpha

CTD Direct Evidence: marker/mechanism

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564

G

arrestin domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978

G

artemin

CTD Direct Evidence: marker/mechanism

NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025

G

autophagy related 10

CTD Direct Evidence: marker/mechanism

NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233

G

ATM serine/threonine kinase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:6504056 PMID:7792600 PMID:8755918 PMID:8797579 PMID:8808599 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase H+ transporting accessory protein 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:22,037,542...22,079,376
Ensembl chr 2:22,037,563...22,065,038

G

ATPase copper transporting beta

CTD Direct Evidence: marker/mechanism

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

aurora kinase A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

beta-1,4-glucuronyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065

G

BAG cochaperone 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

PMID:25231345 PMID:26719535

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

BRCA1 associated RING domain 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast neoplasm

PMID:20077502 PMID:21344236 PMID:25085752 PMID:25741868 PMID:26315354 More...

NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265

G

BCL2 associated X, apoptosis regulator

CTD Direct Evidence: therapeutic

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCAR3 adaptor protein, NSP family member

CTD Direct Evidence: marker/mechanism

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

G

butyrylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

disease_progression

DNA:polymorphism:promoter:-938C>A
CTD Direct Evidence: marker/mechanism
protein:increased expression:breast
associated with Papillomavirus Infections;protein:increased expression:breast

CTD
RGD

PMID:12517783 PMID:16954440 PMID:23621182 PMID:17908970 PMID:18430249 More...

RGD:2293016, RGD:2292908, RGD:2292909

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL2-related protein A1

CTD Direct Evidence: marker/mechanism

PMID:16298037 PMID:17659439

NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998

G

Bcl2-like 1

RGD

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

biglycan

CTD Direct Evidence: marker/mechanism

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

baculoviral IAP repeat-containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 5

disease_progression

mRNA:increased expression:blood
CTD Direct Evidence: marker/mechanism
protein:increased expression:breast

CTD
RGD

PMID:16322251 PMID:16818634 PMID:17086357 PMID:17240580 PMID:18451232 More...

RGD:2293105, RGD:2293104, RGD:2293090, RGD:2293092

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

bone morphogenetic protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

bone morphogenetic protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bone morphogenetic protein receptor type 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Breast neoplasm
ClinVar Annotator: match by term: Breast Neoplasms

PMID:2102266 PMID:12068308 PMID:15035987 PMID:15488754 PMID:17314276 More...

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

BRCA1, DNA repair associated

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor

PMID:824983 PMID:2152385 PMID:2504116 PMID:3175448 PMID:6455195 More...

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

BRCA2, DNA repair associated

susceptibility

DNA:mutation
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
ClinVar Annotator: match by term: BRIP1-related disorder | ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:8075631 PMID:8524414 PMID:8665505 PMID:8673091 PMID:8673092 More...

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

BRF1 general transcription factor IIIB subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 6:132,034,378...132,081,313
Ensembl chr 6:132,037,272...132,081,278

G

BRCA1 interacting DNA helicase 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: BRIP1-related disorder | ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:2455662 PMID:3375802 PMID:9536098 PMID:11301010 PMID:12872252 More...

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

G

Bruton tyrosine kinase

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:24869598 PMID:25082755 PMID:25189416 PMID:25741868 PMID:27199251 More...

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

G

complement C1q binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649

G

similar to human chromosome 11 open reading frame 65

ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:6504056 PMID:7792600 PMID:8755918 PMID:8797579 PMID:8808599 More...

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

cell adhesion molecule 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

G

caspase 6

protein:increased expression:breast

RGD

PMID:15210759 PMID:10574243

RGD:2301338, RGD:2301339

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

CTD Direct Evidence: marker/mechanism

PMID:15601643 PMID:17293864 PMID:17450141 PMID:29915430

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

catalase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

CTD Direct Evidence: marker/mechanism

PMID:19234134 PMID:19288272 PMID:20562527 PMID:21501481

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

C-C motif chemokine ligand 20

CTD Direct Evidence: marker/mechanism

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 5

RGD

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cyclin D1

susceptibility
disease_progression

DNA:polymorphism
CTD Direct Evidence: marker/mechanism
protein:increased expression:breast

CTD
RGD

PMID:12839951 PMID:17255770 PMID:19636701 PMID:20948315 PMID:23839043 More...

RGD:2289126, RGD:2289131

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

DNA, mRNA, protein:hypermethylation, decreased expression:promoter, breast
DNA:hypermethylation:breast

RGD

PMID:11289162 PMID:17549626

RGD:2289158, RGD:2289149

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

DNA:polymorphism:promoter:-677C>T (human)

RGD

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

CTD Direct Evidence: marker/mechanism

PMID:19385967 PMID:23624423

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin H

CTD Direct Evidence: marker/mechanism

NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819

G

chaperonin containing TCP1 subunit 5

CTD Direct Evidence: marker/mechanism

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

CD109 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194

G

CD40 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

CD44 molecule

mRNA:splice variants:breast

RGD

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD74 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cytidine deaminase

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:10811482 PMID:25330770

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cadherin 1

protein:decreased expression:breast
ClinVar Annotator: match by term: Breast tumor
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:hypermethylation:promoter, breast, serum

ClinVar
CTD
RGD

PMID:11305955 PMID:17520682 PMID:19839049 PMID:22703879 PMID:23921149 More...

RGD:2289447, RGD:2289457

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 5

CTD Direct Evidence: marker/mechanism

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cyclin-dependent kinase inhibitor 1A

disease_progression

DNA:snp: :rs3176336

RGD

PMID:16537179 PMID:18174243

RGD:2289656, RGD:2289652

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 2A

susceptibility

protein:decreased expression:breast
CTD Direct Evidence: marker/mechanism
DNA:hypermethylation:promoter
DNA:missense mutation: :p.A148T

CTD
RGD

PMID:20948315 PMID:8686738 PMID:23712779 PMID:15879498

RGD:2289690, RGD:8552384, RGD:2289688

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2A, variant 1

susceptibility

protein:decreased expression:breast
DNA:hypermethylation:promoter

RGD

PMID:8686738 PMID:23712779

RGD:2289690, RGD:8552384

G

cyclin-dependent kinase inhibitor 2A, variant 2

susceptibility

DNA:hypermethylation:promoter

RGD

G

centromere protein F

CTD Direct Evidence: marker/mechanism

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

cofilin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

CF transmembrane conductance regulator

ClinVar Annotator: match by term: Breast Neoplasms

PMID:10925568 PMID:12874665 PMID:15905293 PMID:17539902 PMID:25580864 More...

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

G

checkpoint kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

checkpoint kinase 2

DNA:deletion: ;1100delC
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More...

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

CDC28 protein kinase regulatory subunit 1B

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

claudin 1

CTD Direct Evidence: marker/mechanism

PMID:19579870 PMID:24014025

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 4

CTD Direct Evidence: marker/mechanism

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

chloride intracellular channel 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

clusterin

severity
treatment

RGD

PMID:17203891 PMID:22613415

RGD:8729187, RGD:8764690

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

clusterin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:113,344,501...113,370,077
Ensembl chr 9:113,344,501...113,370,077

G

C-x(9)-C motif containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:44,943,283...44,971,930
Ensembl chr19:44,943,285...44,971,983

G

cannabinoid receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548

G

collagen type VII alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252

G

catechol-O-methyltransferase

CTD Direct Evidence: marker/mechanism

PMID:9407957 PMID:15455371 PMID:16077979

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

coactosin-like F-actin binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689

G

carnitine palmitoyltransferase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

corticotropin releasing hormone receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481

G

CRK like proto-oncogene, adaptor protein

RGD

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

G

colony stimulating factor 1

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16618760 PMID:16618760

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 2

CTD Direct Evidence: therapeutic

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:7541186 PMID:7543699 PMID:7692001 PMID:9018096 PMID:12926135 More...

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

cystatin E/M

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030

G

catenin alpha 1

protein:decreased expression:breast
protein:increased expression:breast

RGD

PMID:17223851 PMID:11431364

RGD:2289792, RGD:2289796

NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910

G

catenin beta 1

disease_progression

CTD Direct Evidence: marker/mechanism
protein:decreased expression:breast

CTD
RGD

PMID:12165863 PMID:25330770 PMID:16707478 PMID:17223851

RGD:2289831, RGD:2289792

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cytosolic thiouridylase subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221

G

cytosolic thiouridylase subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623

G

cullin 5

CTD Direct Evidence: therapeutic

NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666

G

C-X-C motif chemokine ligand 12

CTD Direct Evidence: marker/mechanism

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 9

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

C-X-C motif chemokine receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

cytochrome P450, family 17, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

PMID:19913079 PMID:34426286

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

PMID:11850205 PMID:19639193 PMID:23342035 PMID:28112739 PMID:29701941 More...

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

CTD Direct Evidence: marker/mechanism

PMID:16298037 PMID:17297925

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 24, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383

G

cytochrome P450, family 2, subfamily b, polypeptide 1

CTD Direct Evidence: therapeutic

PMID:8640822 PMID:10811482

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily d, polypeptide 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 3, subfamily a, polypeptide 2

no_association

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15496535 PMID:15180491

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

death associated protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461

G

DNA-damage inducible transcript 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DEK proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808

G

DEPP autophagy regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

desmin

CTD Direct Evidence: marker/mechanism

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

dihydrofolate reductase

CTD Direct Evidence: marker/mechanism

PMID:21501481 PMID:28188287

NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713

G

dicer 1 ribonuclease III

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:21266384 PMID:24728327 PMID:25741868 PMID:26467025 PMID:28492532 More...

NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965

G

iodothyronine deiodinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

dickkopf WNT signaling pathway inhibitor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

delta like canonical Notch ligand 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

G

delta like canonical Notch ligand 4

CTD Direct Evidence: marker/mechanism

NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931

G

DNA methyltransferase 1

CTD Direct Evidence: marker/mechanism

PMID:22520950 PMID:28544374

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 beta

CTD Direct Evidence: marker/mechanism

PMID:18221536 PMID:22520950

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

dihydropyrimidine dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

desmocollin 3

CTD Direct Evidence: marker/mechanism

NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797

G

deltex E3 ubiquitin ligase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522

G

dynein cytoplasmic 2 heavy chain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:4,189,067...4,412,183
Ensembl chr 8:4,189,257...4,412,183

G

E2F transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

endothelin receptor type B

CTD Direct Evidence: therapeutic

NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115

G

eukaryotic translation elongation factor 1 beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737

G

eukaryotic translation elongation factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

EGF containing fibulin extracellular matrix protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

G

ephrin A1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

epidermal growth factor

CTD Direct Evidence: marker/mechanism

PMID:16175315 PMID:21942447 PMID:23064031

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

disease_progression

mRNA:increased expression:lung, tumor (mouse)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16950593 PMID:18768436 PMID:19075277 PMID:20135347 PMID:20941507 More...

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

eukaryotic translation initiation factor 2 subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 6

CTD Direct Evidence: marker/mechanism

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

ETS transcription factor ELK3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084

G

elongator acetyltransferase complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762

G

elongator acetyltransferase complex subunit 3

CTD Direct Evidence: marker/mechanism

NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445

G

EMSY transcriptional repressor, BRCA2 interacting

CTD Direct Evidence: marker/mechanism

NCBI chr 1:152,881,485...152,960,420
Ensembl chr 1:152,883,992...152,953,528

G

endoglin

treatment

RGD

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

enolase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336

G

E1A binding protein p300

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

erythrocyte membrane protein band 4.1-like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607

G

EPH receptor B4

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314

G

erythropoietin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

G

erb-b2 receptor tyrosine kinase 2

disease_progression
treatment

mRNA:increased expression:blood
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm
DNA:amplification
protein:increased expression:breast

CTD
ClinVar
RGD

PMID:10897039 PMID:11222871 PMID:11248153 PMID:11583189 PMID:11970740 More...

RGD:2289921, RGD:10401078, RGD:2289924, RGD:2289922, RGD:2292909, RGD:2289931

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 3

disease_progression

mRNA:increased expression:breast
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm
DNA:amplification

CTD
ClinVar
RGD

PMID:21638049 PMID:26619011 PMID:28114269 PMID:17465220 PMID:18182100

RGD:2289949, RGD:2289942

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

erb-b2 receptor tyrosine kinase 4

susceptibility
disease_progression

mRNA:increased expression:breast
DNA:polymorphism:promoter:-782G>T (human)
DNA:amplification

RGD

PMID:17465220 PMID:18094435 PMID:18182100

RGD:2289949, RGD:2289977, RGD:2289942

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

ERCC excision repair 2, TFIIH core complex helicase subunit

disease_progression

DNA:SNP:exon:p.K751Q (rs13181) (human)

RGD

NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102

G

estrogen receptor 1

DNA:SNP:3' utr:rs2747648 (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast neoplasm

CTD
ClinVar
RGD

PMID:17417639 PMID:20104649 PMID:20458558 PMID:20966540 PMID:21501481 More...

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

disease_progression
treatment

mRNA, protein:increased expression:breast
CTD Direct Evidence: marker/mechanism|therapeutic

CTD
RGD

PMID:17132221 PMID:19434490 PMID:19548127 PMID:18234277 PMID:24047421

RGD:2290017, RGD:8552984

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

estrogen related receptor, alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268

G

ETS proto-oncogene 2, transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319

G

ETS variant transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

Enah/Vasp-like

CTD Direct Evidence: marker/mechanism

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

G

exonuclease 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

coagulation factor III, tissue factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid binding protein 7

CTD Direct Evidence: marker/mechanism

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

Fas ligand

susceptibility

protein:increased expression:breast
DNA:polymorphism:promoter:-844T>C

RGD

PMID:10640988 PMID:17183065

RGD:2290134, RGD:2290054

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

CTD Direct Evidence: marker/mechanism

PMID:17089011 PMID:18281512

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fibrillarin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

F-box and WD repeat domain containing 7

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:17588203 PMID:26619011

NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941

G

FYVE, RhoGEF and PH domain containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563

G

fibroblast growth factor 10

CTD Direct Evidence: marker/mechanism

NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866

G

fibroblast growth factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:200,001,162...200,005,539
Ensembl chr 1:200,001,261...200,005,187

G

fibroblast growth factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466

G

Fibroblast growth factor receptor 1

CTD Direct Evidence: marker/mechanism

PMID:20179196 PMID:21936542

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibroblast growth factor receptor 2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:17525745 PMID:17529967 PMID:17529973 PMID:18438407 PMID:18552176 More...

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibroblast growth factor receptor 4

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242

G

fragile histidine triad diadenosine triphosphatase

severity

RGD

PMID:10930803 PMID:17164758

RGD:2289898, RGD:2289872

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

G

four and a half LIM domains 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

FKBP prolyl isomerase like

CTD Direct Evidence: therapeutic

NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368

G

flagellum associated containing coiled-coil domains 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648

G

filamin A

CTD Direct Evidence: marker/mechanism

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

Fms related receptor tyrosine kinase 1

severity

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23146280 PMID:26124351 PMID:12910290 PMID:11857378

RGD:2289962, RGD:2289961

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

fibronectin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

mRNA, protein:increased expression:breast

RGD

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box A1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188

G

forkhead box C1

disease_progression

DNA, mRNA:increased methylation, decreased expression:breast
DNA:increased methylation:promoter

RGD

PMID:20056007 PMID:20338046

RGD:8662367, RGD:8662370

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

forkhead box M1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box P3

CTD Direct Evidence: marker/mechanism

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

G

forkhead box Q1

CTD Direct Evidence: marker/mechanism

NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377

G

follistatin

CTD Direct Evidence: marker/mechanism

NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571

G

FTO, alpha-ketoglutarate dependent dioxygenase

CTD Direct Evidence: marker/mechanism

NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083

G

polypeptide N-acetylgalactosaminyltransferase 12

ClinVar Annotator: match by term: Breast tumor

PMID:25741868 PMID:28492532 PMID:29546405

NCBI chr 5:61,384,575...61,413,346
Ensembl chr 5:61,384,571...61,413,354

G

polypeptide N-acetylgalactosaminyltransferase 16

CTD Direct Evidence: marker/mechanism

NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705

G

growth differentiation factor 10

CTD Direct Evidence: marker/mechanism

NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343

G

GEN1 Holliday junction 5' flap endonuclease

ClinVar Annotator: match by term: Breast neoplasm

PMID:25741868 PMID:28492532

NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401

G

gap junction protein, alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

G protein subunit alpha i2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

GNAS complex locus

ClinVar Annotator: match by term: Breast Neoplasms

PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More...

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein-coupled estrogen receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glucose-6-phosphate isomerase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

G

glycoprotein nmb

CTD Direct Evidence: marker/mechanism

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

glutathione peroxidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

growth factor receptor bound protein 7

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:17426702 PMID:19075277

NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052

G

glutamate ionotropic receptor kainate type subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375

G

glycogen synthase kinase 3 beta

CTD Direct Evidence: marker/mechanism

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase mu 1

susceptibility
disease_progression

DNA:deletion

RGD

PMID:17624589 PMID:18080216

RGD:2293798, RGD:2293827

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase pi 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

guanylate cyclase 1 soluble subunit alpha 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203

G

granzyme B

CTD Direct Evidence: marker/mechanism

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

H19 imprinted maternally expressed transcript

susceptibility

DNA:SNP
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:breast

CTD
RGD

PMID:28544374 PMID:18708391 PMID:9811352

RGD:2306170, RGD:2306185

NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134

G

H1.2 linker histone, cluster member

CTD Direct Evidence: marker/mechanism

NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635

G

H2A.X variant histone

CTD Direct Evidence: marker/mechanism

PMID:18925433 PMID:21463514

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

H2B clustered histone 12

CTD Direct Evidence: marker/mechanism

NCBI chr17:42,485,699...42,486,162

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

CTD Direct Evidence: marker/mechanism

NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hyaluronan and proteoglycan link protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr16:19,333,106...19,341,243
Ensembl chr16:19,333,106...19,341,243

G

HECT and RLD domain containing E3 ubiquitin protein ligase 2

ClinVar Annotator: match by term: Breast neoplasm

PMID:16397024 PMID:23220880

NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134

G

hes family bHLH transcription factor 1

CTD Direct Evidence: marker/mechanism

PMID:20197467 PMID:21036696

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes-related family bHLH transcription factor with YRPW motif 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312

G

hes-related family bHLH transcription factor with YRPW motif 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218

G

hes-related family bHLH transcription factor with YRPW motif-like

CTD Direct Evidence: marker/mechanism

NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152

G

hematopoietically expressed homeobox

CTD Direct Evidence: marker/mechanism

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

HIC ZBTB transcriptional repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475

G

hypoxia inducible factor 1 subunit alpha

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:24349381 PMID:19064988 PMID:17245699

RGD:2306224, RGD:2293195

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hyaluronan-mediated motility receptor

CTD Direct Evidence: marker/mechanism

NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060

G

heme oxygenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein K

CTD Direct Evidence: marker/mechanism

NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997

G

heterogeneous nuclear ribonucleoprotein L

CTD Direct Evidence: marker/mechanism

NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553

G

heterogeneous nuclear ribonucleoprotein R

CTD Direct Evidence: marker/mechanism

NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867

G

homeo box B13

disease_progression

DNA:hypermethylation
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:24239177 PMID:19250546 PMID:17453342

RGD:2314726, RGD:2314727

NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777

G

homeo box B9

CTD Direct Evidence: marker/mechanism

NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818

G

homeobox D11

CTD Direct Evidence: marker/mechanism

NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783

G

haptoglobin

CTD Direct Evidence: marker/mechanism

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

heparanase

CTD Direct Evidence: marker/mechanism

NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010

G

HRas proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:1904555 PMID:2105486 PMID:3510078 PMID:11150980 PMID:12165863 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

histidine-rich glycoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

G

heat shock protein 90 alpha family class A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein family A (Hsp70) member 1B

CTD Direct Evidence: therapeutic

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 5

protein:increased expression

RGD

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

integrin-binding sialoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693

G

intercellular adhesion molecule 5

CTD Direct Evidence: marker/mechanism

NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Breast Neoplasms

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

indoleamine 2,3-dioxygenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730

G

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

CTD Direct Evidence: marker/mechanism

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

immunoglobulin binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:65,582,832...65,605,078
Ensembl chr X:65,582,821...65,606,049

G

insulin-like growth factor 1

CTD Direct Evidence: marker/mechanism

PMID:17520698 PMID:18398872

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor binding protein 5

CTD Direct Evidence: marker/mechanism

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

insulin-like growth factor binding protein 7

CTD Direct Evidence: therapeutic

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

interleukin 10

CTD Direct Evidence: marker/mechanism

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 13

susceptibility
treatment

DNA:SNPs, haplotypes:promoter, exon:-1512A>C, -1055C>T, 2044G>A (human)

RGD

PMID:18989750 PMID:17438063

RGD:8549503, RGD:8549557

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

treatment

associated with Arthritis, Experimental

RGD

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 1 beta

CTD Direct Evidence: marker/mechanism

PMID:16298037 PMID:17516992 PMID:28212736

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 24

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:16298037 PMID:21671747

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

interleukin 6

susceptibility

associated with obesity;DNA:polymorphism:promoter:-174G>C(human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16298037 PMID:17516992 PMID:19435922 PMID:19446661 PMID:11426023

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7 receptor

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

insulin receptor

RGD

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

G

intersectin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124

G

jagged canonical Notch ligand 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

jagged canonical Notch ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

Jun proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

junction plakoglobin

severity
no_association

RGD

PMID:7604000 PMID:11276001 PMID:17008277

RGD:2291881, RGD:2291873, RGD:2291883

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

lysine acetyltransferase 6A

severity

mRNA:increased expression:breast (human)

RGD

NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606

G

potassium voltage-gated channel subfamily H member 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740

G

lysine demethylase 4C

severity

mRNA:increased expression:breast (human)
human gene in a mouse model

RGD

PMID:19784073 PMID:23129632

RGD:9587479, RGD:9587482

NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818

G

lysine demethylase 5B

severity

mRNA:increased expression:breast (human)

RGD

NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872

G

kinase insert domain receptor

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20135347 PMID:35917945 PMID:14511401

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

KiSS-1 metastasis-suppressor

severity
disease_progression

RGD

PMID:17914099 PMID:16320113

RGD:2292123, RGD:2292135

NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612

G

KIT proto-oncogene receptor tyrosine kinase

disease_progression
severity

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20941507 PMID:17848740 PMID:21388062 PMID:14669790 PMID:17867595

RGD:2292424, RGD:12910741, RGD:2292423, RGD:2292425

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

kelch domain containing 10

CTD Direct Evidence: marker/mechanism

NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941

G

kelch domain containing 7A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:152,218,604...152,224,707
Ensembl chr 5:152,221,033...152,224,551

G

kallikrein related-peptidase 10

severity

CTD Direct Evidence: marker/mechanism
DNA:hypermethylation:exon (human)

CTD
RGD

PMID:16800735 PMID:12087468 PMID:19150938 PMID:17585892

RGD:2314850, RGD:2314845, RGD:2314847

NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376

G

lysine methyltransferase 2D

CTD Direct Evidence: marker/mechanism

NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325

G

KRAS proto-oncogene, GTPase

human breast adenocarcinoma cell line, OMIM:114480
CTD Direct Evidence: marker/mechanism

CTD
RGD

NCBI chr 4:178,185,418...178,218,484

G

keratin 14

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799

G

keratin 18

CTD Direct Evidence: marker/mechanism

PMID:20061804 PMID:25330770

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166

G

keratin 5

CTD Direct Evidence: marker/mechanism

NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850

G

keratin 8

CTD Direct Evidence: marker/mechanism

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

L3MBTL histone methyl-lysine binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

CTD Direct Evidence: marker/mechanism

NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395

G

ladybird homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690

G

lactate dehydrogenase A-like 6B

CTD Direct Evidence: marker/mechanism

NCBI chr 1:45,997,845...45,999,268
Ensembl chr 1:45,991,991...45,999,272

G

lactate dehydrogenase B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

lymphoid enhancer binding factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794

G

leptin

CTD Direct Evidence: marker/mechanism

PMID:21353530 PMID:35191604

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

leptin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

leucine-rich repeat-containing G protein-coupled receptor 6

CTD Direct Evidence: marker/mechanism

PMID:18507500 PMID:23535733

NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945

G

LIM domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:91,090,279...91,092,772
Ensembl chr10:91,090,280...91,092,775

G

LLGL scribble cell polarity complex component 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:45,379,423...45,394,096
Ensembl chr10:45,379,515...45,394,094

G

LLGL scribble cell polarity complex component 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525

G

lysyl oxidase-like 2

CTD Direct Evidence: marker/mechanism

PMID:19330836 PMID:24014025

NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067

G

lysophosphatidic acid receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895

G

leucine rich repeat containing 3B

CTD Direct Evidence: marker/mechanism

NCBI chr15:9,973,580...10,050,891
Ensembl chr15:9,969,983...10,051,066

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:1904555 PMID:2105486 PMID:3510078 PMID:11150980 PMID:12727991 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

lymphocyte-specific protein 1

CTD Direct Evidence: marker/mechanism

PMID:17529967 PMID:20453838

NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416

G

macrophage immunometabolism regulator

CTD Direct Evidence: marker/mechanism

NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733

G

mitotic arrest deficient 1 like 1

NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703

G

mal, T-cell differentiation protein

CTD Direct Evidence: marker/mechanism

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mannosidase, alpha, class 2C, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:57,537,879...57,549,691
Ensembl chr 8:57,537,321...57,549,690

G

mitogen activated protein kinase kinase 4

susceptibility

DNA:SNP, haplotype

RGD

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen activated protein kinase kinase 7

CTD Direct Evidence: marker/mechanism

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

G

mitogen-activated protein kinase kinase kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

G

microcephalin 1

severity

protein:decreased expression:breast (human)

RGD

NCBI chr16:71,021,855...71,224,067
Ensembl chr16:71,024,588...71,224,122

G

MDM2 proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MDM4 regulator of p53

CTD Direct Evidence: marker/mechanism

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

MDS1 and EVI1 complex locus

CTD Direct Evidence: marker/mechanism

NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590

G

mediator complex subunit 12

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast neoplasm

PMID:25038752 PMID:26437033 PMID:26619011

NCBI chr X:66,404,807...66,427,775
Ensembl chr X:66,404,760...66,428,387

G

mediator complex subunit 28

CTD Direct Evidence: marker/mechanism

NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583

G

Meis homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265

G

methyltransferase 6, tRNA N3-cytidine

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,683,820...6,699,013
Ensembl chr16:6,583,465...6,698,975

G

milk fat globule EGF and factor V/VIII domain containing

CTD Direct Evidence: marker/mechanism

NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073

G

macrophage migration inhibitory factor

CTD Direct Evidence: marker/mechanism

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504

G

microRNA 101-2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467

G

microRNA 10a

CTD Direct Evidence: marker/mechanism

NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280

G

microRNA 10b

CTD Direct Evidence: marker/mechanism

NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546

G

microRNA 126a

CTD Direct Evidence: marker/mechanism

NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180

G

microRNA 127

CTD Direct Evidence: marker/mechanism

NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311

G

microRNA 132

CTD Direct Evidence: marker/mechanism

NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796

G

microRNA 141

CTD Direct Evidence: marker/mechanism

NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332

G

microRNA 145

CTD Direct Evidence: marker/mechanism

NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727

G

microRNA 146a

CTD Direct Evidence: marker/mechanism

NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610

G

microRNA 152

CTD Direct Evidence: marker/mechanism

NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020

G

microRNA 200b

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:19839049 PMID:20099276

NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366

G

microRNA 200c

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:19839049 PMID:20099276

NCBI chr 4:157,523,679...157,523,747

G

microRNA 205

CTD Direct Evidence: marker/mechanism

NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985

G

microRNA 206

CTD Direct Evidence: marker/mechanism

NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332

G

microRNA 214

CTD Direct Evidence: marker/mechanism

NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481

G

microRNA 221

CTD Direct Evidence: marker/mechanism

NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573

G

microRNA 222

CTD Direct Evidence: marker/mechanism

NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006

G

microRNA 24-2

CTD Direct Evidence: marker/mechanism

NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790

G

microRNA 29a

CTD Direct Evidence: marker/mechanism

NCBI chr 4:59,650,608...59,650,695

G

microRNA 301a

CTD Direct Evidence: marker/mechanism

NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435

G

microRNA 342

CTD Direct Evidence: marker/mechanism

NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367

G

microRNA 345

CTD Direct Evidence: marker/mechanism

NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122

G

microRNA 429

CTD Direct Evidence: marker/mechanism

NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543

G

microRNA 489

CTD Direct Evidence: marker/mechanism

NCBI chr 4:31,693,355...31,693,460
Ensembl chr 4:31,693,355...31,693,460

G

marker of proliferation Ki-67

CTD Direct Evidence: marker/mechanism

PMID:15706428 PMID:18768436 PMID:19436038

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

membrane metallo-endopeptidase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 13

disease_progression

RGD

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 14

CTD Direct Evidence: marker/mechanism

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 2

disease_progression

protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter:-1306C>T (human)
protein:increased expression:breast

CTD
RGD

PMID:18398872 PMID:18507500 PMID:16949931 PMID:17851253 PMID:15538048 More...

RGD:2290401, RGD:8655999, RGD:8547818, RGD:2290392

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

disease_progression
no_association

protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, CDS:rs3918241, rs2274756 (p.R668Q) (human)
DNA:SNPs, haplotype:rs17577, rs3787268 (human)

CTD
RGD

PMID:19617202 PMID:18172859 PMID:20725776 PMID:21151179 PMID:21159820 More...

RGD:2290343, RGD:8547893, RGD:8547839, RGD:8547837, RGD:8547827, RGD:8547818

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

mitochondrial ribosomal protein L13

CTD Direct Evidence: marker/mechanism

NCBI chr 7:86,951,541...86,973,147
Ensembl chr 7:86,951,541...86,973,577

G

mitochondrial ribosomal protein L19

CTD Direct Evidence: marker/mechanism

NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053

G

mitochondrial ribosomal protein L9

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095

G

mitochondrial ribosomal protein S22

CTD Direct Evidence: marker/mechanism

NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291

G

mitochondrial ribosomal protein S23

CTD Direct Evidence: marker/mechanism

NCBI chr10:72,999,033...73,006,791
Ensembl chr10:72,998,497...73,006,264

G

mitochondrial ribosomal protein S28

CTD Direct Evidence: marker/mechanism

NCBI chr 2:92,820,676...92,951,302
Ensembl chr 2:92,820,606...92,951,284

G

mitochondrial ribosomal protein S7

CTD Direct Evidence: marker/mechanism

NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129

G

macrophage stimulating 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416

G

metallothionein 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

G

metadherin

CTD Direct Evidence: marker/mechanism

NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413

G

methylenetetrahydrofolate reductase

CTD Direct Evidence: marker/mechanism

PMID:16777985 PMID:17595805 PMID:28114181

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

mechanistic target of rapamycin kinase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms

PMID:22729223 PMID:24631838 PMID:25599672 PMID:25741868 PMID:25799227 More...

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

5-methyltetrahydrofolate-homocysteine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822

G

MYC proto-oncogene, bHLH transcription factor

treatment

mRNA:increased expression:mammary gland (mouse)

RGD

PMID:20820192 PMID:22439659

RGD:7207428, RGD:7241009

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myosin, heavy chain 9

CTD Direct Evidence: marker/mechanism

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

G

N-acetyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520

G

nuclear receptor coactivator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664

G

nuclear receptor coactivator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451

G

nuclear receptor coactivator 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594

G

nuclear receptor co-repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NADH:ubiquinone oxidoreductase core subunit S3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824

G

nectin cell adhesion molecule 2

CTD Direct Evidence: therapeutic

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

G

NFE2 like bZIP transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFKB inhibitor alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nischarin

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668

G

neuromedin B receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462

G

NOP9 nucleolar protein

CTD Direct Evidence: marker/mechanism

NCBI chr15:29,243,853...29,252,220
Ensembl chr15:29,243,862...29,252,220

G

nitric oxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

CTD Direct Evidence: marker/mechanism

PMID:15375496 PMID:19671875

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

notch receptor 1

CTD Direct Evidence: marker/mechanism

PMID:21036696 PMID:21679465

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

notch receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025

G

notch receptor 4

CTD Direct Evidence: marker/mechanism

PMID:21036696 PMID:21679465

NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465

G

NAD(P)H quinone dehydrogenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320

G

nuclear receptor subfamily 2, group F, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123

G

nuclear receptor subfamily 2, group F, member 6

CTD Direct Evidence: marker/mechanism

NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459

G

neuronal cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992

G

neuregulin 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

nuclear receptor interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761

G

nuclear receptor binding SET domain protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641

G

NOP2/Sun RNA methyltransferase 6

CTD Direct Evidence: marker/mechanism

NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006

G

nudix hydrolase 17

CTD Direct Evidence: marker/mechanism

NCBI chr 2:184,241,468...184,243,960
Ensembl chr 2:184,241,468...184,243,960

G

nudix hydrolase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:56,628,265...56,643,104
Ensembl chr 5:56,628,265...56,643,104

G

occludin

CTD Direct Evidence: marker/mechanism

PMID:17459053 PMID:24014025

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

O-linked N-acetylglucosamine (GlcNAc) transferase

severity

RGD

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

G

poly(A) binding protein, cytoplasmic 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744

G

progestagen associated endometrial protein

CTD Direct Evidence: marker/mechanism

NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430

G

p21 (RAC1) activated kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

G

p21 (RAC1) activated kinase 2

RGD

NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816

G

partner and localizer of BRCA2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:17200668 PMID:17200671 PMID:17200672 PMID:24033266 PMID:24136930 More...

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

poly (ADP-ribose) polymerase 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

poly(rC) binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500

G

proliferating cell nuclear antigen

disease_progression

RGD

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

phosphodiesterase 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434

G

platelet derived growth factor subunit A

CTD Direct Evidence: marker/mechanism

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

platelet derived growth factor receptor beta

RGD

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

3-phosphoinositide dependent protein kinase-1

CTD Direct Evidence: marker/mechanism

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

G

PDZ domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514

G

platelet and endothelial cell adhesion molecule 1

RGD

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

G

period circadian regulator 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607

G

progesterone receptor

CTD Direct Evidence: marker/mechanism

PMID:19436038 PMID:21501481

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

prohibitin 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

phosphoglycerate dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

RGD:2313763, RGD:2290476

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

phosphoinositide-3-kinase regulatory subunit 1

mRNA:increased expression:mammary tumor (mouse)

RGD

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

Pim-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

CTD Direct Evidence: marker/mechanism

PMID:19671742 PMID:19681904 PMID:32621833

NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785

G

phospholipase A2 group 4A

CTD Direct Evidence: marker/mechanism

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

G

phospholipase A and acyltransferase 3

RGD

NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667

G

pleckstrin homology and coiled-coil domain containing D1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:100,340,655...100,371,942
Ensembl chr 6:100,340,655...100,371,941

G

PMS1 homolog 2, mismatch repair system component

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:23709753 PMID:24033266 PMID:25741868 PMID:27146957 PMID:28466842 More...

NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066

G

DNA polymerase epsilon, catalytic subunit

ClinVar Annotator: match by term: Breast Neoplasms

PMID:23263490 PMID:23447401 PMID:24525744 PMID:24844595 PMID:25224212 More...

NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939

G

PPARG coactivator 1 beta

CTD Direct Evidence: marker/mechanism

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

CTD Direct Evidence: marker/mechanism

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 1, regulatory subunit 12B

CTD Direct Evidence: marker/mechanism

NCBI chr13:46,199,418...46,397,108
Ensembl chr13:46,201,251...46,397,108

G

protein phosphatase 2 scaffold subunit A alpha

ClinVar Annotator: match by term: Breast Neoplasms

PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More...

NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129

G

protein regulator of cytokinesis 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

protein kinase C, alpha

protein:decreased expression:breast

RGD

PMID:9474241 PMID:15454252 PMID:17965220

RGD:2292463, RGD:2292458, RGD:2292446

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

G

protease, serine, 46

CTD Direct Evidence: marker/mechanism

NCBI chr 8:110,829,275...110,841,049
Ensembl chr 8:110,829,266...110,841,123

G

presenilin 2

human gene: protein:amino acid substitution:R62H, R71W

RGD

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: BRIP1-related disorder | ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:1336932 PMID:1945792 PMID:9140396 PMID:9241266 PMID:9259288 More...

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin E synthase

protein:increased expression:breast

RGD

NCBI chr 3:14,177,892...14,189,236

G

prostaglandin-endoperoxide synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586

G

prostaglandin-endoperoxide synthase 2

susceptibility

mRNA, protein:increased expression:breast
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:breast

CTD
RGD

PMID:16127422 PMID:16870006 PMID:17285134 PMID:18498876 PMID:18509974 More...

RGD:2300210, RGD:2300120, RGD:2300129

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

parathyroid hormone-like hormone

CTD Direct Evidence: marker/mechanism

NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847

G

protein tyrosine kinase 2

DNA:amplification
protein:increased expression:breast

RGD

PMID:16457699 PMID:16136050

RGD:2292558, RGD:2292559

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

G

protein tyrosine phosphatase, receptor type, D

CTD Direct Evidence: marker/mechanism

NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396

G

RAD50 double strand break repair protein

treatment

human gene in a rat model

RGD

PMID:16474176 PMID:11373271

RGD:2300220, RGD:9831192

NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396

G

RAD51 recombinase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035

G

RAD51 paralog B

CTD Direct Evidence: marker/mechanism

NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979

G

RAD51 paralog C

CTD Direct Evidence: marker/mechanism

PMID:20400964 PMID:28825726

NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248

G

RAD54 like

CTD Direct Evidence: marker/mechanism

NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070

G

Raf-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: therapeutic

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

RALY RNA binding protein-like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:87,482,747...88,274,329
Ensembl chr 2:87,482,755...88,274,452

G

retinoic acid receptor, alpha

CTD Direct Evidence: marker/mechanism

NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142

G

retinoic acid receptor, beta

CTD Direct Evidence: therapeutic

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

G

Ras association domain family member 1

RGD

PMID:17325427 PMID:12222680

RGD:2291979, RGD:2291977

NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164

G

RB transcriptional corepressor 1

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:14672398 PMID:19234134 PMID:20948315 PMID:11108660 PMID:1567185

RGD:2291991, RGD:9698451

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RB1-inducible coiled-coil 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560

G

RNA binding motif protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr X:14,348,909...14,352,387
Ensembl chr X:14,348,910...14,353,580

G

retinol binding protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

G

RCC1 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:134,271,870...134,281,556
Ensembl chr 1:134,271,857...134,280,781

G

RecQ like helicase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20154269 PMID:16728586 PMID:16322341

RGD:2298762, RGD:2298763

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RALBP1 associated Eps domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:32,049,455...32,322,317
Ensembl chr X:32,049,399...32,317,414

G

regulator of G-protein signaling 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

ras homolog family member A

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

RIB43A domain with coiled-coils 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863

G

RIC8 guanine nucleotide exchange factor A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467

G

required for meiotic nuclear division 1 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 1:40,859,829...40,894,376
Ensembl chr 1:40,859,829...40,894,314

G

ring finger protein 115

CTD Direct Evidence: marker/mechanism

NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823

G

ring finger protein 182

CTD Direct Evidence: marker/mechanism

NCBI chr17:21,026,110...21,081,760
Ensembl chr17:21,030,214...21,094,911

G

Rho-associated coiled-coil containing protein kinase 1

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571

G

receptor tyrosine kinase-like orphan receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155

G

ribosomal protein L23A

CTD Direct Evidence: marker/mechanism

NCBI chr10:63,076,660...63,079,346
Ensembl chr10:63,076,066...63,079,346
Ensembl chr15:63,076,066...63,079,346

G

ribosomal protein L31

CTD Direct Evidence: marker/mechanism

NCBI chr 9:41,647,397...41,651,441
Ensembl chr 9:41,647,426...41,662,129
Ensembl chr 8:41,647,426...41,662,129

G

ribosomal protein lateral stalk subunit P2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645

G

ribosomal protein S4, X-linked

CTD Direct Evidence: marker/mechanism

NCBI chr X:67,298,522...67,302,965
Ensembl chr X:67,298,525...67,303,019
Ensembl chr 4:67,298,525...67,303,019

G

ribosomal protein S6

CTD Direct Evidence: marker/mechanism

NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602

G

ribosomal protein S6 kinase B2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078

G

ribosomal protein S7

CTD Direct Evidence: marker/mechanism

NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145

G

ribosomal protein S8

CTD Direct Evidence: marker/mechanism

NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

CTD Direct Evidence: marker/mechanism

NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417

G

R-spondin 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:28,283,914...28,368,661
Ensembl chr 1:28,283,914...28,367,061

G

RUNX family transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

retinoid X receptor beta

CTD Direct Evidence: marker/mechanism

NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773

G

S100 calcium-binding protein A4

RGD

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

serpin family B member 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408

G

serpin family B member 5

CTD Direct Evidence: marker/mechanism

NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756

G

SET binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556

G

SET domain containing 2, histone lysine methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489

G

splicing factor 3b, subunit 1

ClinVar Annotator: match by term: Breast neoplasm

PMID:23634996 PMID:26619011

NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300

G

splicing factor 3b, subunit 2

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759

G

secreted frizzled-related protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

G

secreted frizzled-related protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

G

secreted frizzled-related protein 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224

G

SHC adaptor protein 1

ClinVar Annotator: match by term: Breast neoplasm

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

G

serine hydroxymethyltransferase 1

no_association

DNA:SNP:CDS:no association between SNP rs1979277, rs1979276 or rs3783 and susceptibility to breast cancer
CTD Direct Evidence: marker/mechanism

PMID:17311260 PMID:17595805 PMID:17311260

RGD:2300328, RGD:2300328

NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820

G

SIM bHLH transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:53,827,601...53,907,219
Ensembl chr20:53,828,364...53,907,212

G

sirtuin 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

solute carrier family 10 member 6

CTD Direct Evidence: marker/mechanism

NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037

G

solute carrier family 16 member 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 22, member 18

CTD Direct Evidence: marker/mechanism

NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975

G

solute carrier family 28 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464

G

solute carrier family 2 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 10

CTD Direct Evidence: marker/mechanism

NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690

G

solute carrier family 2 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 5

CTD Direct Evidence: therapeutic

NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 39 member 6

CTD Direct Evidence: marker/mechanism

NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417

G

solute carrier family 5 member 5

CTD Direct Evidence: therapeutic

NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697

G

SMAD family member 4

ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm

PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 PMID:9679244 More...

NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438

G

snail family transcriptional repressor 1

CTD Direct Evidence: marker/mechanism

PMID:11850205 PMID:24014025

NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969

G

snail family transcriptional repressor 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200

G

synuclein, gamma

CTD Direct Evidence: marker/mechanism

NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368

G

sorting nexin 32

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,801,090...202,818,731
Ensembl chr 1:202,802,394...202,818,743

G

suppressor of cytokine signaling 1

DNA:hypermethylation

RGD

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

suppressor of cytokine signaling 2

disease_progression

RGD

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:17965603 PMID:19385967 PMID:19756960 PMID:20562527 PMID:15168344

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

spermatogenesis associated 18

CTD Direct Evidence: marker/mechanism

NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687

G

secreted phosphoprotein 1

CTD Direct Evidence: marker/mechanism

PMID:18949741 PMID:22531848

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

protein:altered localization:cytoplasm
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21357651 PMID:19830888

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

sterol regulatory element binding transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848

G

ST14 transmembrane serine protease matriptase

disease_progression

protein:increased expression:breast

RGD

NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517

G

StAR-related lipid transfer domain containing 8

CTD Direct Evidence: marker/mechanism

NCBI chr X:64,079,079...64,196,052
Ensembl chr X:64,124,574...64,196,052

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 5A

protein:decreased expression:breast
CTD Direct Evidence: marker/mechanism
protein:altered localization:nucleus

CTD
RGD

PMID:15609129 PMID:16133357 PMID:15609129

RGD:2291930, RGD:2291932

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

G

stanniocalcin 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973

G

stathmin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

G

syntaxin binding protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663

G

sulfotransferase family 1A member 1

onset
disease_progression
no_association

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:30120701 PMID:16875543 PMID:16328031 PMID:12373301 PMID:15377847 More...

RGD:2301046, RGD:1581437, RGD:2301051, RGD:2301048, RGD:2301047, RGD:2301049

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

spectrin repeat containing nuclear envelope protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322

G

synaptojanin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687

G

TAFA chemokine like family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 4:129,437,466...129,671,320
Ensembl chr 4:129,437,467...129,671,249

G

TRAF family member-associated NFKB activator

CTD Direct Evidence: marker/mechanism

NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264

G

T-box transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708

G

telomerase reverse transcriptase

susceptibility
disease_progression

DNA:SNPs:promoter:-1381C>T,-659G>A,-244C>T (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:plasma
mRNA:increased expression:breast

CTD
RGD

PMID:23535731 PMID:17848914 PMID:14654933 PMID:17974999 PMID:17616810

RGD:2291983, RGD:2291969, RGD:2291981, RGD:2291987

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

transcription factor AP-2 alpha

CTD Direct Evidence: therapeutic

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

G

trefoil factor 1

disease_progression

protein:increased expression:breast

RGD

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

tissue factor pathway inhibitor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600

G

transferrin receptor

CTD Direct Evidence: marker/mechanism

PMID:16904380 PMID:19238537

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transglutaminase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

thrombospondin 1

CTD Direct Evidence: therapeutic

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

thymocyte selection associated family member 2

CTD Direct Evidence: therapeutic

NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400

G

TIMP metallopeptidase inhibitor 2

protein:decreased expression:breast
protein:decreased expression:serum

RGD

PMID:17642161 PMID:17240786

RGD:2290392, RGD:2290398

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TIMP metallopeptidase inhibitor 4

RGD

NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558

G

TLE family member 3, transcriptional corepressor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:61,857,791...61,903,505
Ensembl chr 8:61,858,200...61,903,493

G

transmembrane protein with EGF-like and two follistatin-like domains 2

DNA:hypermethylation:promoter

RGD

NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475

G

transmembrane protein 25

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389

G

tumor necrosis factor

CTD Direct Evidence: marker/mechanism

PMID:16298037 PMID:17516992 PMID:19446661

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 10b

disease_progression

protein:increased expression:breast

RGD

NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

TNFAIP3 interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625

G

DNA topoisomerase II alpha

disease_progression

CTD Direct Evidence: marker/mechanism
DNA:deletion (human)
DNA:amplification, deletion (human)

CTD
RGD

PMID:11583189 PMID:12006526 PMID:16234514 PMID:22204715 PMID:19996222 More...

RGD:2315120, RGD:2315127, RGD:2315129

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

TOX high mobility group box family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148

G

tumor protein p53

susceptibility

DNA:missense mutation: :p.R72P
ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
ClinVar Annotator: match by term: BRIP1-related disorder | ClinVar Annotator: match by term: Breast Neoplasms | ClinVar Annotator: match by term: Breast neoplasm | ClinVar Annotator: match by term: Breast tumor
CTD Direct Evidence: marker/mechanism
DNA:mutations:exon

ClinVar
CTD
RGD

PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493