RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Parasitic Eye Infections
Accession: DOID:9004432
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Definition: Mild to severe infections of the eye and its adjacent structures (adnexa) by adult or larval protozoan or metazoan parasites.
Synonyms: exact_synonym: Parasitic Eye Infection; Parasitic Ocular Infection; Parasitic Ocular Infections
primary_id: MESH:D015822
alt_id: RDO:0006731
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Tlr4
toll-like receptor 4
IEP
mRNA,protein:increased expression:cornea
RGD
PMID:21155840
RGD:7777095
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Il1rl1
interleukin 1 receptor-like 1
treatment
ISO
mRNA:increased expression:brain:
RGD
PMID:24657070 PMID:23148283
RGD:11561855 , RGD:40400713
NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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Il33
interleukin 33
ISO
protein:increased expression:brain:
RGD
PMID:23148283 PMID:24076431
RGD:40400713 , RGD:40400715
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Il5
interleukin 5
ISO
RGD
PMID:8361777
RGD:11354948
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Mag
myelin-associated glycoprotein
disease_progression
ISO
RGD
PMID:20399564
RGD:27226693
NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
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Mbp
myelin basic protein
disease_progression
ISO
RGD
PMID:20399564
RGD:27226693
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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Mobp
myelin-associated oligodendrocyte basic protein
disease_progression
ISO
RGD
PMID:20399564
RGD:27226693
NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563
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Il1r1
interleukin 1 receptor type 1
ISO
RGD
PMID:19168746
RGD:8662882
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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Tlr4
toll-like receptor 4
ISO
RGD
PMID:11884755
RGD:7794682
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Anxa1
annexin A1
ISO
RGD
PMID:22740770
RGD:7421536
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Il10
interleukin 10
ISO
RGD
PMID:19026704
RGD:7365028
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il17a
interleukin 17A
treatment
ISO
protein:increased expression:aqueous humor (human)
RGD
PMID:22927448 PMID:22927448
RGD:8698652 , RGD:8698652
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il27
interleukin 27
disease_progression
ISO
mRNA:increased expression:eye, cervical lymph node (mouse)
RGD
PMID:29779048
RGD:126790500
NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
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Nod2
nucleotide-binding oligomerization domain containing 2
susceptibility
ISO
DNA:snp:3' utr:g.*397A>C (rs3135499)(human)
RGD
PMID:23100559
RGD:8547527
NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
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