Mobp (myelin-associated oligodendrocyte basic protein) - Rat Genome Database

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Gene: Mobp (myelin-associated oligodendrocyte basic protein) Rattus norvegicus
Analyze
Symbol: Mobp
Name: myelin-associated oligodendrocyte basic protein
RGD ID: 3101
Description: A structural constituent of myelin sheath. Involved in central nervous system myelin formation. Located in myelin sheath. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in frontotemporal dementia. Orthologous to human MOBP (myelin associated oligodendrocyte basic protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC105491; Mobp81; Mobp81p; myelin-associated oligodendrocytic basic protein; Myelin-associated/Oligodendrocytic Basic Protein-81; RNMOBP81P
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08128,824,420 - 128,854,492 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08128,025,119 - 128,055,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,118,618 - 125,144,099 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,138,354 - 125,163,833 (+)NCBI
Celera8119,014,616 - 119,040,060 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10077700   PMID:12477932   PMID:15489334   PMID:15625715   PMID:17634366   PMID:18614015   PMID:22871113  


Genomics

Comparative Map Data
Mobp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08128,824,420 - 128,854,492 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08128,025,119 - 128,055,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,118,618 - 125,144,099 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,138,354 - 125,163,833 (+)NCBI
Celera8119,014,616 - 119,040,060 (+)NCBICelera
Cytogenetic Map8q32NCBI
MOBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl339,467,198 - 39,529,479 (+)EnsemblGRCh38hg38GRCh38
GRCh38339,467,680 - 39,529,497 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37339,509,171 - 39,570,988 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,484,074 - 39,542,863 (+)NCBINCBI36hg18NCBI36
Build 34339,518,557 - 39,540,989NCBI
Celera339,450,698 - 39,509,485 (+)NCBI
Cytogenetic Map3p22.1NCBI
HuRef339,552,592 - 39,614,603 (+)NCBIHuRef
CHM1_1339,460,108 - 39,522,029 (+)NCBICHM1_1
Mobp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,978,740 - 120,010,554 (+)NCBIGRCm39mm39
GRCm39 Ensembl9119,978,773 - 120,010,550 (+)Ensembl
GRCm389120,149,742 - 120,181,488 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,149,707 - 120,181,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,058,860 - 120,085,209 (+)NCBIGRCm37mm9NCBIm37
MGSCv369119,998,440 - 120,030,182 (+)NCBImm8
Celera9120,618,557 - 120,644,888 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map971.41NCBI
Mobp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542029,902,036 - 29,957,364 (-)NCBIChiLan1.0ChiLan1.0
MOBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1339,651,728 - 39,715,632 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl339,688,104 - 39,699,486 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0339,372,102 - 39,450,066 (+)NCBIMhudiblu_PPA_v0panPan3
LOC607986
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1239,121,277 - 9,176,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl239,121,319 - 9,161,972 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,156,665 - 9,211,227 (+)NCBI
ROS_Cfam_1.0239,406,125 - 9,460,980 (+)NCBI
UMICH_Zoey_3.1239,219,099 - 9,273,643 (+)NCBI
UNSW_CanFamBas_1.0239,362,022 - 9,416,643 (+)NCBI
UU_Cfam_GSD_1.0239,355,681 - 9,409,917 (+)NCBI
LOC101956318
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,525,415 - 195,572,004 (+)NCBI
SpeTri2.0NW_00493647328,663,986 - 28,709,394 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11324,138,078 - 24,186,838 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,450,254 - 26,497,554 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227428
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1221,041,714 - 1,077,514 (+)NCBI
ChlSab1.1 Ensembl221,041,783 - 1,079,241 (+)Ensembl
Vero_WHO_p1.0NW_023666041166,166,889 - 166,222,254 (-)NCBI
Mobp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473078,759,681 - 78,794,632 (-)NCBI

Position Markers
D8Wox13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,893,153 - 119,893,319 (+)MAPPER
Rnor_6.08128,848,035 - 128,848,200NCBIRnor6.0
Rnor_5.08128,048,720 - 128,048,885UniSTSRnor5.0
RGSC_v3.48125,141,773 - 125,141,938UniSTSRGSC3.4
Celera8119,038,304 - 119,038,469UniSTS
Cytogenetic Map8q32UniSTS
RH127596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,895,179 - 119,895,388 (+)MAPPER
Rnor_6.08128,850,061 - 128,850,269NCBIRnor6.0
Rnor_5.08128,050,746 - 128,050,954UniSTSRnor5.0
RGSC_v3.48125,143,799 - 125,144,007UniSTSRGSC3.4
Celera8119,039,760 - 119,039,968UniSTS
RH 3.4 Map81286.9UniSTS
Cytogenetic Map8q32UniSTS
RH144588  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,891,405 - 119,891,565 (+)MAPPER
Rnor_6.08128,846,289 - 128,846,448NCBIRnor6.0
Rnor_5.08128,046,974 - 128,047,133UniSTSRnor5.0
RGSC_v3.48125,140,027 - 125,140,186UniSTSRGSC3.4
Celera8119,036,558 - 119,036,717UniSTS
RH 3.4 Map81286.9UniSTS
Cytogenetic Map8q32UniSTS
BG376552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,887,635 - 119,887,782 (+)MAPPER
Rnor_6.08128,842,519 - 128,842,665NCBIRnor6.0
Rnor_5.08128,043,204 - 128,043,350UniSTSRnor5.0
RGSC_v3.48125,136,257 - 125,136,403UniSTSRGSC3.4
Celera8119,032,788 - 119,032,934UniSTS
RH 3.4 Map81287.0UniSTS
Cytogenetic Map8q32UniSTS
BI281206  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,899,047 - 119,899,198 (+)MAPPER
Rnor_6.08128,853,929 - 128,854,079NCBIRnor6.0
Rnor_5.08128,054,614 - 128,054,764UniSTSRnor5.0
RGSC_v3.48125,147,667 - 125,147,817UniSTSRGSC3.4
Celera8119,043,628 - 119,043,778UniSTS
RH 3.4 Map81314.4UniSTS
Cytogenetic Map8q32UniSTS
Mobp  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,887,003 - 119,887,726 (+)MAPPER
Rnor_6.08128,841,887 - 128,842,609NCBIRnor6.0
Rnor_5.08128,042,572 - 128,043,294UniSTSRnor5.0
RGSC_v3.48125,135,625 - 125,136,347UniSTSRGSC3.4
Celera8119,032,156 - 119,032,878UniSTS
Cytogenetic Map8q32UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)883894304128894304Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)889058229132243842Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8100873811133307652Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8100873811133307652Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102051964133307652Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8104682575133307652Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)8104682575133307652Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8107769005129956433Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:415
Count of miRNA genes:236
Interacting mature miRNAs:277
Transcripts:ENSRNOT00000025279, ENSRNOT00000025343, ENSRNOT00000041868
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 27
Low 1 6 25 9 16 9 6 6 14 9 19 9 6
Below cutoff 1 6 1 1 2 1 2 3 23 1 20 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001389272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001389273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_356705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_594173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_594174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF157498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X87900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000025279   ⟹   ENSRNOP00000025279
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8128,829,680 - 128,842,739 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000025343   ⟹   ENSRNOP00000025344
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8128,824,508 - 128,850,358 (+)Ensembl
RefSeq Acc Id: NM_001389272   ⟹   NP_001376201
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,602 - 119,887,859 (+)NCBI
RefSeq Acc Id: NM_001389273   ⟹   NP_001376202
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,602 - 119,887,859 (+)NCBI
RefSeq Acc Id: NM_012720   ⟹   NP_036852
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,602 - 119,895,480 (+)NCBI
Rnor_6.08128,824,508 - 128,850,361 (+)NCBI
Rnor_5.08128,025,119 - 128,055,171 (+)NCBI
RGSC_v3.48125,118,618 - 125,144,099 (+)RGD
Celera8119,014,616 - 119,040,060 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080854   ⟹   XP_038936782
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080855   ⟹   XP_038936783
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080856   ⟹   XP_038936784
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080857   ⟹   XP_038936785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,543 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080858   ⟹   XP_038936786
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080859   ⟹   XP_038936787
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,517 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080860   ⟹   XP_038936788
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,504 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080861   ⟹   XP_038936789
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,544 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080862   ⟹   XP_038936790
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,513 - 119,899,605 (+)NCBI
RefSeq Acc Id: XM_039080863   ⟹   XP_038936791
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28119,869,533 - 119,899,605 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036852   ⟸   NM_012720
- Peptide Label: isoform 1
- UniProtKB: Q63327 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025279   ⟸   ENSRNOT00000025279
RefSeq Acc Id: ENSRNOP00000025344   ⟸   ENSRNOT00000025343
RefSeq Acc Id: XP_038936786   ⟸   XM_039080858
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936782   ⟸   XM_039080854
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936783   ⟸   XM_039080855
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936784   ⟸   XM_039080856
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936788   ⟸   XM_039080860
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038936790   ⟸   XM_039080862
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038936787   ⟸   XM_039080859
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936791   ⟸   XM_039080863
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038936785   ⟸   XM_039080857
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038936789   ⟸   XM_039080861
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001376201   ⟸   NM_001389272
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001376202   ⟸   NM_001389273
- Peptide Label: isoform 2
Protein Domains
FYVE_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696384
Promoter ID:EPDNEW_R6907
Type:multiple initiation site
Name:Mobp_1
Description:myelin-associated oligodendrocyte basic protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08128,824,482 - 128,824,542EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3101 AgrOrtholog
Ensembl Genes ENSRNOG00000018700 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000025279 UniProtKB/Swiss-Prot
  ENSRNOP00000025344 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025279 UniProtKB/Swiss-Prot
  ENSRNOT00000025343 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7320248 IMAGE-MGC_LOAD
InterPro FYVE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25037 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187383 IMAGE-MGC_LOAD
NCBI Gene 25037 ENTREZGENE
Pfam FYVE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mobp PhenoGen
TIGR TC208077
UniProt B1WBR5_RAT UniProtKB/TrEMBL
  MOBP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q63328 UniProtKB/Swiss-Prot
  Q63343 UniProtKB/Swiss-Prot
  Q63519 UniProtKB/Swiss-Prot
  Q64266 UniProtKB/Swiss-Prot
  Q9QZV5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Mobp  myelin-associated oligodendrocyte basic protein  Mobp  myelin-associated oligodendrocytic basic protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Mobp  myelin-associated oligodendrocytic basic protein  Mobp81  Myelin-associated/Oligodendrocytic Basic Protein-81  Symbol and Name updated 625702 APPROVED
2002-06-10 Mobp81  Myelin-associated/Oligodendrocytic Basic Protein-81      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression restricted to the CNS myelin 633191
gene_product member of the central nervous system (CNS) myelin-constituting protein family 633191
gene_product member of the central nervous system (CNS) myelin-constituting proteins 633191