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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Acanthamoeba Keratitis
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Accession:DOID:9001552 term browser browse the term
Definition:Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.
Synonyms:exact_synonym: Acanthamoeba Keratitides
 primary_id: MESH:D015823
 xref: EFO:0007126


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Acanthamoeba Keratitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 IEP mRNA,protein:increased expression:cornea RGD PMID:21155840 RGD:7777095 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19051
    disease by infectious agent 2249
      parasitic infectious disease 327
        Parasitic Eye Infections 13
          Acanthamoeba Keratitis 1
Path 2
Term Annotations click to browse term
  disease 19051
    disease of anatomical entity 18384
      nervous system disease 14258
        Neurologic Manifestations 10339
          sensory system disease 7253
            eye disease 3732
              Eye Infections 59
                Parasitic Eye Infections 13
                  Acanthamoeba Keratitis 1
paths to the root