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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-acetylaminofluorene
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Accession:CHEBI:76343 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is replaced by a 9H-fluoren-4-yl group.
Synonyms:exact_synonym: N-(9H-fluoren-4-yl)acetamide
 related_synonym: 4-AAF;   4-Acetylaminofluoren;   4-fluorenylacetamide;   4AAF;   Formula=C15H13NO;   InChI=1S/C15H13NO/c1-10(17)16-14-8-4-6-12-9-11-5-2-3-7-13(11)15(12)14/h2-8H,9H2,1H3,(H,16,17);   InChIKey=PHPWISAFHNEMSR-UHFFFAOYSA-N;   N-4-fluorenylacetamide;   N-9H-fluoren-4-ylacetamide;   N-fluoren-4-ylacetamide;   SMILES=C=12C3=C(CC1C=CC=C2NC(=O)C)C=CC=C3
 xref: CAS:28322-02-3
 xref_mesh: MESH:C028676
 xref: PMID:2366818;   PMID:2417700;   PMID:3785275;   PMID:7508825;   Reaxys:2975269


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4-acetylaminofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase increases expression ISO 4-acetylaminofluorene results in increased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 increases expression ISO 4-acetylaminofluorene results in increased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G AEN apoptosis enhancing nuclease decreases expression ISO 4-acetylaminofluorene results in decreased expression of AEN mRNA CTD PMID:17070881 NCBI chr15:88,604,683...88,632,281
Ensembl chr15:88,621,337...88,632,281 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 increases expression ISO 4-acetylaminofluorene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases expression ISO 4-acetylaminofluorene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G APOA2 apolipoprotein A2 decreases expression ISO 4-acetylaminofluorene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631 		JBrowse link
G APOA4 apolipoprotein A4 decreases expression ISO 4-acetylaminofluorene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOC3 apolipoprotein C3 decreases expression ISO 4-acetylaminofluorene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D increases expression ISO 4-acetylaminofluorene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO 4-acetylaminofluorene results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 decreases expression ISO 4-acetylaminofluorene results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G C7 complement C7 decreases expression ISO 4-acetylaminofluorene results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,492...41,020,216 		JBrowse link
G CBLC Cbl proto-oncogene C increases expression ISO 4-acetylaminofluorene results in increased expression of CBLC mRNA CTD PMID:17070881 NCBI chr19:44,777,869...44,800,652
Ensembl chr19:44,777,869...44,800,652 		JBrowse link
G CCNG1 cyclin G1 increases expression ISO 4-acetylaminofluorene results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CD276 CD276 molecule increases expression ISO 4-acetylaminofluorene results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr15:73,683,944...73,714,514
Ensembl chr15:73,683,966...73,714,514 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression ISO 4-acetylaminofluorene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CPQ carboxypeptidase Q decreases expression ISO 4-acetylaminofluorene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654 		JBrowse link
G CRYAB crystallin alpha B decreases expression ISO 4-acetylaminofluorene results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO 4-acetylaminofluorene results in decreased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G EPCAM epithelial cell adhesion molecule increases expression ISO 4-acetylaminofluorene results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601 		JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression ISO 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G FAS Fas cell surface death receptor increases expression
decreases expression		 ISO 4-acetylaminofluorene results in increased expression of FAS mRNA
4-acetylaminofluorene results in decreased expression of FAS mRNA		 CTD PMID:17070881 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase decreases expression ISO 4-acetylaminofluorene results in decreased expression of FHIT mRNA CTD PMID:17070881 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression ISO 4-acetylaminofluorene results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 increases expression ISO 4-acetylaminofluorene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 increases expression ISO 4-acetylaminofluorene results in increased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr12:56,763,324...56,787,790
Ensembl chr12:56,752,161...56,787,790 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha increases expression ISO 4-acetylaminofluorene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase increases expression ISO 4-acetylaminofluorene results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator increases expression ISO 4-acetylaminofluorene results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 decreases expression ISO 4-acetylaminofluorene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237 		JBrowse link
G POR cytochrome p450 oxidoreductase increases expression ISO 4-acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G RHOBTB2 Rho related BTB domain containing 2 increases expression ISO 4-acetylaminofluorene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr 8:22,950,813...23,020,199
Ensembl chr 8:22,987,417...23,020,509 		JBrowse link
G SERPINA7 serpin family A member 7 decreases expression ISO 4-acetylaminofluorene results in decreased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727 		JBrowse link
G SLC16A10 solute carrier family 16 member 10 increases expression ISO 4-acetylaminofluorene results in increased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr 6:111,087,503...111,231,194
Ensembl chr 6:111,087,503...111,231,194 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 increases expression ISO 4-acetylaminofluorene results in increased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671 		JBrowse link
G SUGCT succinyl-CoA:glutarate-CoA transferase increases expression ISO 4-acetylaminofluorene results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr 7:40,135,005...41,038,816
Ensembl chr 7:40,135,005...40,860,763 		JBrowse link
G SULF2 sulfatase 2 decreases expression ISO 4-acetylaminofluorene results in decreased expression of SULF2 mRNA CTD PMID:17070881 NCBI chr20:47,657,406...47,786,627
Ensembl chr20:47,656,197...47,786,616 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 increases expression ISO 4-acetylaminofluorene results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G TSC22D1 TSC22 domain family member 1 decreases expression ISO 4-acetylaminofluorene results in decreased expression of TSC22D1 mRNA CTD PMID:15089088 NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147 		JBrowse link
G ZMAT3 zinc finger matrin-type 3 decreases expression ISO 4-acetylaminofluorene results in decreased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 3:179,017,223...179,072,513
Ensembl chr 3:178,960,121...179,072,215 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 26503
    role 26325
      biological role 26304
        mitogen 3605
          4-acetylaminofluorene 40
Path 2
Term Annotations click to browse term
  CHEBI ontology 26503
    subatomic particle 26479
      composite particle 26479
        hadron 26479
          baryon 26479
            nucleon 26479
              atomic nucleus 26479
                atom 26479
                  main group element atom 26216
                    p-block element atom 26216
                      carbon group element atom 25661
                        carbon atom 25623
                          organic molecular entity 25623
                            heteroorganic entity 25006
                              organochalcogen compound 24600
                                organooxygen compound 24194
                                  carbon oxoacid 22810
                                    carboxylic acid 22790
                                      carboacyl group 20089
                                        univalent carboacyl group 20089
                                          carbamoyl group 19614
                                            carboxamide 19614
                                              acetamides 15060
                                                4-acetylaminofluorene 40
paths to the root