SLC16A10 (solute carrier family 16 member 10) - Rat Genome Database
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Gene: SLC16A10 (solute carrier family 16 member 10) Homo sapiens
Analyze
Symbol: SLC16A10
Name: solute carrier family 16 member 10
RGD ID: 731538
HGNC Page HGNC
Description: Exhibits thyroid hormone transmembrane transporter activity. Involved in thyroid hormone transport. Localizes to basolateral plasma membrane; cell junction; and intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aromatic amino acid transporter 1; MCT 10; MCT10; monocarboxylate transporter 10; PRO0813; solute carrier family 16 (aromatic amino acid transporter), member 10; solute carrier family 16 (monocarboxylic acid transporters), member 10; solute carrier family 16, member 10; solute carrier family 16, member 10 (aromatic amino acid transporter); T-type amino acid transporter 1; TAT1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6111,087,503 - 111,231,194 (+)EnsemblGRCh38hg38GRCh38
GRCh386111,087,503 - 111,231,194 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,408,728 - 111,544,608 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366111,515,502 - 111,650,907 (+)NCBINCBI36hg18NCBI36
Build 346111,515,501 - 111,650,906NCBI
Celera6112,155,354 - 112,291,161 (+)NCBI
Cytogenetic Map6q21NCBI
HuRef6108,979,921 - 109,115,795 (+)NCBIHuRef
CHM1_16111,671,814 - 111,807,532 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-nitropropane  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-diaminotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-nitro-p-phenylenediamine  (ISO)
2-nitropropane  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-acetylaminofluorene  (ISO)
4-nitro-1,2-phenylenediamine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
atrazine  (ISO)
azathioprine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clofibric acid  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
dicrotophos  (EXP)
diethyl hydrogen phosphate  (ISO)
dioxygen  (ISO)
disulfiram  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP)
entinostat  (EXP)
eugenol  (EXP)
flutamide  (ISO)
folic acid  (ISO)
fonofos  (EXP)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
L-methionine  (ISO)
metformin  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
orphenadrine  (ISO)
oxaliplatin  (ISO)
oxycodone  (ISO)
paracetamol  (ISO)
parathion  (EXP)
phenformin  (ISO)
phenylephrine  (ISO)
pirinixic acid  (ISO)
propanal  (EXP)
rotenone  (ISO)
SB 431542  (EXP)
silicon dioxide  (EXP)
sodium arsenate  (ISO)
sunitinib  (EXP)
terbufos  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
urethane  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)
zoledronic acid  (EXP)

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11278508   PMID:11278976   PMID:11827462   PMID:12477932   PMID:12739169   PMID:15918515   PMID:18195088   PMID:18337592   PMID:20167367   PMID:21315799   PMID:21486766   PMID:21508134  
PMID:21873635   PMID:21886157   PMID:22286219   PMID:23383108   PMID:24816252   PMID:25113059   PMID:26779635   PMID:26972000   PMID:27492966   PMID:28514442   PMID:28754537   PMID:31091453  
PMID:31595333   PMID:32296183   PMID:32694731  


Genomics

Comparative Map Data
SLC16A10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6111,087,503 - 111,231,194 (+)EnsemblGRCh38hg38GRCh38
GRCh386111,087,503 - 111,231,194 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376111,408,728 - 111,544,608 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366111,515,502 - 111,650,907 (+)NCBINCBI36hg18NCBI36
Build 346111,515,501 - 111,650,906NCBI
Celera6112,155,354 - 112,291,161 (+)NCBI
Cytogenetic Map6q21NCBI
HuRef6108,979,921 - 109,115,795 (+)NCBIHuRef
CHM1_16111,671,814 - 111,807,532 (+)NCBICHM1_1
Slc16a10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391039,909,528 - 40,018,262 (-)NCBIGRCm39mm39
GRCm381040,033,532 - 40,142,270 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1040,033,532 - 40,142,258 (-)EnsemblGRCm38mm10GRCm38
MGSCv371039,753,341 - 39,862,060 (-)NCBIGRCm37mm9NCBIm37
MGSCv361039,765,179 - 39,831,671 (-)NCBImm8
Celera1040,919,892 - 41,029,158 (-)NCBICelera
Cytogenetic Map10B1NCBI
Slc16a10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02045,138,433 - 45,260,155 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2045,143,453 - 45,260,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02046,863,305 - 46,913,500 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02046,979,059 - 46,979,589 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42044,211,651 - 44,325,332 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12044,234,662 - 44,348,343 (-)NCBI
Celera2044,173,196 - 44,274,083 (-)NCBICelera
Cytogenetic Map20q12NCBI
Slc16a10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541135,758,612 - 35,871,164 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541135,758,612 - 35,871,179 (+)NCBIChiLan1.0ChiLan1.0
SLC16A10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16112,968,652 - 113,107,508 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6112,968,668 - 113,106,721 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06108,889,644 - 109,037,479 (+)NCBIMhudiblu_PPA_v0panPan3
SLC16A10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1267,705,037 - 67,719,985 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11267,612,563 - 67,720,763 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc16a10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365646,823,054 - 6,925,702 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC16A10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl176,998,359 - 77,138,639 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1176,998,359 - 77,139,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,714,334 - 86,743,447 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC16A10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11362,645,692 - 62,787,508 (-)NCBI
ChlSab1.1 Ensembl1362,646,876 - 62,786,048 (-)Ensembl
Slc16a10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249162,096,224 - 2,239,856 (+)NCBI

Position Markers
RH124087  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,434,447 - 111,434,730UniSTSGRCh37
Build 366111,541,140 - 111,541,423RGDNCBI36
Celera6112,181,018 - 112,181,301RGD
Cytogenetic Map6q21-q22UniSTS
HuRef6109,005,584 - 109,005,867UniSTS
SLC16A10_831  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,543,605 - 111,544,309UniSTSGRCh37
Build 366111,650,298 - 111,651,002RGDNCBI36
Celera6112,290,156 - 112,290,862RGD
HuRef6109,114,786 - 109,115,496UniSTS
EV4Pm  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371675,170,947 - 75,171,099UniSTSGRCh37
GRCh376111,477,111 - 111,477,267UniSTSGRCh37
Build 366111,583,804 - 111,583,960RGDNCBI36
Celera1659,463,889 - 59,464,041UniSTS
Celera6112,223,681 - 112,223,837RGD
HuRef1660,921,660 - 60,921,812UniSTS
HuRef6109,048,343 - 109,048,499UniSTS
STS-N30257  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376111,543,990 - 111,544,121UniSTSGRCh37
Build 366111,650,683 - 111,650,814RGDNCBI36
Celera6112,290,543 - 112,290,674RGD
Cytogenetic Map6q21-q22UniSTS
HuRef6109,115,173 - 109,115,304UniSTS
GeneMap99-GB4 RH Map6466.61UniSTS
NCBI RH Map61401.4UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3411
Count of miRNA genes:1117
Interacting mature miRNAs:1391
Transcripts:ENST00000368850, ENST00000368851, ENST00000419619, ENST00000439288, ENST00000465319
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 9 10 7 3 23 3 604 414 5 19 25 7 11 574 1
Low 900 1242 1554 543 984 395 2388 729 1552 304 994 1439 152 635 1236 3
Below cutoff 1511 1721 157 73 870 62 1347 1044 2142 86 426 143 18 558 970

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000368850   ⟹   ENSP00000357843
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,177,212 - 111,231,194 (+)Ensembl
RefSeq Acc Id: ENST00000368851   ⟹   ENSP00000357844
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,087,503 - 111,231,194 (+)Ensembl
RefSeq Acc Id: ENST00000419619   ⟹   ENSP00000399601
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,172,695 - 111,178,714 (+)Ensembl
RefSeq Acc Id: ENST00000439288   ⟹   ENSP00000387501
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,172,695 - 111,177,712 (+)Ensembl
RefSeq Acc Id: ENST00000465319
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,172,695 - 111,177,712 (+)Ensembl
RefSeq Acc Id: ENST00000612036   ⟹   ENSP00000483868
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6111,087,503 - 111,177,706 (+)Ensembl
RefSeq Acc Id: NM_018593   ⟹   NP_061063
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,087,503 - 111,231,194 (+)NCBI
GRCh376111,408,728 - 111,544,608 (+)NCBI
Build 366111,515,502 - 111,650,907 (+)NCBI Archive
Celera6112,155,354 - 112,291,161 (+)RGD
HuRef6108,979,921 - 109,115,795 (+)ENTREZGENE
CHM1_16111,671,814 - 111,807,532 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006715329   ⟹   XP_006715392
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,087,503 - 111,178,711 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011535422   ⟹   XP_011533724
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,087,503 - 111,196,030 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017010237   ⟹   XP_016865726
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,175,976 - 111,227,124 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001743158
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,087,503 - 111,227,125 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_061063   ⟸   NM_018593
- UniProtKB: Q8TF71 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006715392   ⟸   XM_006715329
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011533724   ⟸   XM_011535422
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016865726   ⟸   XM_017010237
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000387501   ⟸   ENST00000439288
RefSeq Acc Id: ENSP00000483868   ⟸   ENST00000612036
RefSeq Acc Id: ENSP00000399601   ⟸   ENST00000419619
RefSeq Acc Id: ENSP00000357844   ⟸   ENST00000368851
RefSeq Acc Id: ENSP00000357843   ⟸   ENST00000368850
Protein Domains
MFS

Promoters
RGD ID:7208901
Promoter ID:EPDNEW_H10196
Type:initiation region
Name:SLC16A10_1
Description:solute carrier family 16 member 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386111,087,503 - 111,087,563EPDNEW
RGD ID:6804793
Promoter ID:HG_KWN:54654
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000368853,   OTTHUMT00000041822,   UC003PUR.2
Position:
Human AssemblyChrPosition (strand)Source
Build 366111,515,109 - 111,515,609 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21-23.2(chr6:108944899-132067720)x1 copy number loss See cases [RCV000051196] Chr6:108944899..132067720 [GRCh38]
Chr6:109266102..132388860 [GRCh37]
Chr6:109372795..132430553 [NCBI36]
Chr6:6q21-23.2
pathogenic
GRCh38/hg38 6q21-22.1(chr6:107370141-115827482)x1 copy number loss See cases [RCV000138006] Chr6:107370141..115827482 [GRCh38]
Chr6:107691345..116148646 [GRCh37]
Chr6:107798038..116255339 [NCBI36]
Chr6:6q21-22.1
pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1
pathogenic
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1 copy number loss See cases [RCV000139465] Chr6:96609994..122161548 [GRCh38]
Chr6:97057870..122482694 [GRCh37]
Chr6:97164591..122524393 [NCBI36]
Chr6:6q16.1-22.31
pathogenic
GRCh38/hg38 6q21-22.31(chr6:106503719-125781219)x1 copy number loss See cases [RCV000141587] Chr6:106503719..125781219 [GRCh38]
Chr6:106951594..126102365 [GRCh37]
Chr6:107058287..126144058 [NCBI36]
Chr6:6q21-22.31
pathogenic
GRCh38/hg38 6q21(chr6:110020558-111200711)x3 copy number gain See cases [RCV000141546] Chr6:110020558..111200711 [GRCh38]
Chr6:110341761..111521914 [GRCh37]
Chr6:110448454..111628607 [NCBI36]
Chr6:6q21
uncertain significance
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1 copy number loss See cases [RCV000142287] Chr6:103279465..113934239 [GRCh38]
Chr6:103727340..114255403 [GRCh37]
Chr6:103834033..114362096 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1 copy number loss See cases [RCV000143227] Chr6:100054889..120488154 [GRCh38]
Chr6:100502765..120809300 [GRCh37]
Chr6:100609486..120850999 [NCBI36]
Chr6:6q16.3-22.31
pathogenic
GRCh37/hg19 6q21(chr6:109564793-112223595)x1 copy number loss See cases [RCV000447293] Chr6:109564793..112223595 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1 copy number loss See cases [RCV000445666] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1 copy number loss not provided [RCV000682693] Chr6:95549951..116684929 [GRCh37]
Chr6:6q16.1-22.1
pathogenic
GRCh37/hg19 6q21(chr6:110419878-111698827)x1 copy number loss not provided [RCV000682707] Chr6:110419878..111698827 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:111503087-111747187)x3 copy number gain not provided [RCV000682709] Chr6:111503087..111747187 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
NM_018593.5(SLC16A10):c.1111C>T (p.Leu371=) single nucleotide variant not provided [RCV000939236] Chr6:111218838 [GRCh38]
Chr6:111540041 [GRCh37]
Chr6:6q21
likely benign
NM_018593.5(SLC16A10):c.562T>C (p.Leu188=) single nucleotide variant not provided [RCV000885254] Chr6:111177285 [GRCh38]
Chr6:111498488 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:111503087-111731131)x3 copy number gain not provided [RCV001005841] Chr6:111503087..111731131 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21-22.31(chr6:110981075-119608396)x1 copy number loss not provided [RCV000848701] Chr6:110981075..119608396 [GRCh37]
Chr6:6q21-22.31
pathogenic
GRCh37/hg19 6q21(chr6:111437859-111765932)x3 copy number gain not provided [RCV000845713] Chr6:111437859..111765932 [GRCh37]
Chr6:6q21
uncertain significance
NM_018593.5(SLC16A10):c.738G>C (p.Leu246=) single nucleotide variant not provided [RCV000963621] Chr6:111177461 [GRCh38]
Chr6:111498664 [GRCh37]
Chr6:6q21
benign
NM_018593.5(SLC16A10):c.252G>A (p.Val84=) single nucleotide variant not provided [RCV000912854] Chr6:111088004 [GRCh38]
Chr6:111409207 [GRCh37]
Chr6:6q21
likely benign
GRCh37/hg19 6q21(chr6:109564694-112232351)x1 copy number loss not provided [RCV001007557] Chr6:109564694..112232351 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:111434909-111662102)x3 copy number gain not provided [RCV001005840] Chr6:111434909..111662102 [GRCh37]
Chr6:6q21
likely benign
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3 copy number gain Microcephaly [RCV001251053] Chr6:101296547..117004249 [GRCh37]
Chr6:6q16.3-22.1
pathogenic
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1 copy number loss Deletion 6q16 q21 [RCV001263224] Chr6:98949950..114533905 [GRCh37]
Chr6:6q16.1-21
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:17027 AgrOrtholog
COSMIC SLC16A10 COSMIC
Ensembl Genes ENSG00000112394 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000357843 UniProtKB/TrEMBL
  ENSP00000357844 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000387501 UniProtKB/TrEMBL
  ENSP00000399601 UniProtKB/TrEMBL
  ENSP00000483868 UniProtKB/TrEMBL
Ensembl Transcript ENST00000368850 UniProtKB/TrEMBL
  ENST00000368851 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000419619 UniProtKB/TrEMBL
  ENST00000439288 UniProtKB/TrEMBL
  ENST00000612036 UniProtKB/TrEMBL
GTEx ENSG00000112394 GTEx
HGNC ID HGNC:17027 ENTREZGENE
Human Proteome Map SLC16A10 Human Proteome Map
InterPro MCT10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:117247 UniProtKB/Swiss-Prot
NCBI Gene 117247 ENTREZGENE
OMIM 607550 OMIM
PANTHER PTHR11360:SF119 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38197 PharmGKB
PROSITE MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087X138_HUMAN UniProtKB/TrEMBL
  H0Y3W8_HUMAN UniProtKB/TrEMBL
  H0Y5M8_HUMAN UniProtKB/TrEMBL
  MOT10_HUMAN UniProtKB/Swiss-Prot
  Q05BR4_HUMAN UniProtKB/TrEMBL
  Q8TF71 ENTREZGENE
  Q9P1I2_HUMAN UniProtKB/TrEMBL
UniProt Secondary B3KWY0 UniProtKB/Swiss-Prot
  Q6ZMG0 UniProtKB/Swiss-Prot
  Q8WVI5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC16A10  solute carrier family 16 member 10    solute carrier family 16 (aromatic amino acid transporter), member 10  Symbol and/or name change 5135510 APPROVED
2013-07-23 SLC16A10  solute carrier family 16 (aromatic amino acid transporter), member 10    solute carrier family 16, member 10 (aromatic amino acid transporter)  Symbol and/or name change 5135510 APPROVED
2011-09-01 SLC16A10  solute carrier family 16, member 10 (aromatic amino acid transporter)  SLC16A10  solute carrier family 16, member 10 (aromatic amino acid transporter)  Symbol and/or name change 5135510 APPROVED