Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RHOBTB2 (Rho related BTB domain containing 2) Homo sapiens
Symbol: RHOBTB2
Name: Rho related BTB domain containing 2
Description: Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; actin cytoskeleton organization; and regulation of cell shape. Predicted to colocalize with the plasma membrane. Implicated in early infantile epileptic encephalopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DBC2; deleted in breast cancer 2 gene protein; EIEE64; KIAA0717; p83; Rho-related BTB domain containing 2; rho-related BTB domain-containing protein 2
Mus musculus (house mouse) : Rhobtb2 (Rho-related BTB domain containing 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rhobtb2 (Rho-related BTB domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhobtb2 (Rho related BTB domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RHOBTB2 (Rho related BTB domain containing 2)
Canis lupus familiaris (dog) : RHOBTB2 (Rho related BTB domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhobtb2 (Rho related BTB domain containing 2)
Sus scrofa (pig) : RHOBTB2 (Rho related BTB domain containing 2)
Chlorocebus sabaeus (African green monkey) : RHOBTB2 (Rho related BTB domain containing 2)
Heterocephalus glaber (naked mole-rat) : Rhobtb2 (Rho related BTB domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl822,987,417 - 23,020,199 (+)Ensembl
GRCh38822,987,251 - 23,020,199 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37822,844,930 - 22,877,710 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,913,407 - 22,933,653 (+)NCBINCBI36hg18NCBI36
Build 34822,913,406 - 22,933,653NCBI
Celera821,807,292 - 21,840,065 (+)NCBI
Cytogenetic Map8p21.3NCBI
HuRef821,389,448 - 21,422,165 (+)NCBIHuRef
CHM1_1823,047,120 - 23,079,900 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RHOBTB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320529
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.