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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cephamycin
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Accession:CHEBI:55429 term browser browse the term
Definition:Any member of the cephamycin sub-group of cephem antibiotics, differing from cephalosporins in possessing a methoxy group at the 7alpha-position of the cephem nucleus, and in being resistant to beta-lactamase.
Synonyms:related_synonym: Formula=C8H7NO4SR2;   SMILES=N12C([C@](*)(C1=O)OC)SCC(=C2C(O)=O)*;   cephamycins
 xref: PMID:1107228



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cefotetan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Cefotetan results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
cefoxitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IFNG mRNA] CTD PMID:37269894 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] CTD PMID:37269894 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL10 mRNA] CTD PMID:37269894 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL1B mRNA] CTD PMID:37269894 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL6 mRNA] CTD PMID:37269894 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of MYD88 mRNA] CTD PMID:37269894 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of RELA mRNA] CTD PMID:37269894 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RT1-CE16 RT1 class I, locus CE16 affects expression ISO Cefoxitin affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G RT1-Ha RT1 class II, locus Ha affects expression ISO Cefoxitin affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,760,118...4,770,244
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TGFB1 mRNA] CTD PMID:37269894 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TLR2 mRNA] CTD PMID:37269894 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TNF mRNA] CTD PMID:37269894 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TRAF6 mRNA] CTD PMID:37269894 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    role 19850
      biological role 19848
        antimicrobial agent 18257
          heterocyclic antibiotic 3029
            organonitrogen heterocyclic antibiotic 2995
              beta-lactam antibiotic 815
                cephem 549
                  cephamycin 14
                    cefminox 0
                    cefotetan 1
                    cefoxitin 13
                    cephamycin C 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      carbon group element atom 19756
                        carbon atom 19753
                          organic molecular entity 19753
                            heteroorganic entity 19521
                              organochalcogen compound 19281
                                organooxygen compound 19199
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      carboacyl group 17706
                                        univalent carboacyl group 17706
                                          carbamoyl group 17550
                                            carboxamide 17550
                                              lactam 8391
                                                beta-lactam 830
                                                  beta-lactam antibiotic 815
                                                    cephem 549
                                                      cephamycin 14
                                                        cefminox 0
                                                        cefotetan 1
                                                        cefoxitin 13
                                                        cephamycin C 0
paths to the root