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cephamycin +     
(R)-iclaprim +  
(R)-temafloxacin +  
(S)-iclaprim +  
(S)-temafloxacin +  
4-\{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl\}-thiazol-2-yl-ammonium +  
amikacin  
amikacin disulfate 
amoxicillin +   
amoxicillin trihydrate +   
ampicillin +   
antimycobacterial drug +   
antitreponemal drug +  
apramycin 
arasertaconazole +   
arbekacin +  
Augmentin  
avibactam 
avibactam sodium +  
Avycaz 
azithromycin +   
azlocillin 
aztreonam +   
benzyl isothiocyanate  
benzylpenicillin +   
biapenem 
brodimoprim 
carbapenem MM22383 
carbenicillin +  
carumonam 
cefaclor  
cefadroxil +   
cefaloridine  
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cefamandole +  
cefamandole nafate 
cefamandole sodium 
cefatrizine 
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cefditoren +  
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cefepime hydrochloride 
cefiderocol 
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cefmenoxime +  
cefmetazole  
cefminox 
Cefminox sodium 
cefodizime 
cefonicid  
cefoperazone  
ceforanide 
cefotaxime  
cefotetan  
A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms.
cefotetan disodium 
cefotiam +   
cefotiam dihydrochloride 
cefotiam hexetil dihydrochloride 
cefoxitin  
cefpiramide 
cefpodoxime +   
cefpodoxime proxetil 
cefprozil 
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ceftazidime +   
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ceftibuten dihydrate 
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cefuzonam 
cephalexin +   
cephalexin monohydrate 
cephamycin C 
cephapirin 
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cethromycin 
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chlorphenesin +   
chlorquinaldol 
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cinoxacin  
ciprofloxacin +   
ciprofloxacin dihydrochloride 
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ciprofloxacin hydrochloride hydrate 
clarithromycin  
clavulanic acid 
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fumagillin +   
furagin 
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garenoxacin 
gemifloxacin +  
hetacillin 
hexamethylenetetramine +  
humulone 
iclaprim 
imipenem +   
isoconazole  
isoconazole nitrate 
josamycin  
kanamycin A sulfate 
levofloxacin  
linezolid  
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malachite green cation +   
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nafcillin  
nalidixic acid  
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norfloxacin  
ofloxacin +   
oritavancin +  
oritavancin bisphosphate 
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oxolinic acid 
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pefloxacin mesylate 
penamecillin 
pipemidic acid  
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potassium clavulanate +   
pristinamycin 
pristinamycin IA +  
pristinamycin IIA +  
prontosil  
ribostamycin +  
ribostamycin sulfate 
ristocetin 
rolitetracycline 
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roxithromycin +   
salicylhydroxamic acid  
sertaconazole  
sertaconazole nitrate 
silver(1+) sulfadiazinate 
sirolimus +   
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spectinomycin dihydrochloride 
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spiramycin I 
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streptomycin +   
sulfabenzamide 
sulfacetamide 
sulfachloropyridazine 
sulfadoxine 
sulfamazone 
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sulfaperin 
sulfaphenazole  
sulfathiourea 
sulfisoxazole +   
sulfisoxazole diolamine 
teicoplanin  
telavancin +  
telavancin hydrochloride 
temafloxacin 
tetracycline +   
tetracycline zwitterion 
thiostrepton  
thiram  
tiamulin  
ticarcillin 
tigecycline +   
tinidazole  
trimethoprim +   
trovafloxacin  
trovafloxacin mesylate 
vancomycin +   
virginiamycin 
virginiamycin S1 +  
xibornol 

Synonyms
Exact Synonyms: (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ;   7beta-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
Related Synonyms: (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid ;   Formula=C17H17N7O8S4 ;   InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1 ;   InChIKey=SRZNHPXWXCNNDU-IXOPCIAXSA-N ;   SMILES=[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)C1SC(S1)=C(C(N)=O)C(O)=O)OC)C(O)=O ;   cefotetanum
Alternate IDs: CHEBI:558729
Xrefs: Beilstein:5697364 "Beilstein" ;   CAS:69712-56-7 "ChemIDplus" ;   CAS:69712-56-7 "KEGG COMPOUND" ;   DrugBank:DB01330 ;   Drug_Central:547 "DrugCentral" ;   KEGG:C06886 ;   KEGG:D00260 ;   LINCS:LSM-5961
Xref Mesh: MESH:D015313
Xrefs: PMID:17664321 "ChEMBL" ;   PMID:29017833 "Europe PMC" ;   Patent:DE2824559 ;   Patent:US4263432 ;   Reaxys:5697364 "Reaxys" ;   Wikipedia:Cefotetan
Cyclic Relationships: is_conjugate_acid_of CHEBI:59358

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.