Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pentetic acid
go back to main search page
Accession:CHEBI:35739 term browser browse the term
Definition:A pentacarboxylic acid that has formula C14H23N3O10.
Synonyms:exact_synonym: 2,2',2'',2''',2''''-(ethane-1,2-diylnitrilo)pentaacetic acid
 related_synonym: 1,1,4,7,7-diethylenetriaminepentaacetic acid;   Complexon V;   DTPA;   Formula=C14H23N3O10;   H5dtpa;   InChI=1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);   InChIKey=QPCDCPDFJACHGM-UHFFFAOYSA-N;   N,N,N',N'',N''-diethylenetriaminepentaacetic acid;   N,N-bis[2-[bis(carboxymethyl)amino]ethyl]glycine;   SMILES=OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O;   Titriplex V;   [[(carboxymethyl)imino]bis(1,2-ethanediylnitrilo)tetraacetic acid];   diethylenetriamine-N,N,N',N'',N''-pentaacetic acid;   diethylenetriaminepentaacetic acid;   diethylenetriaminepentacetic acid;   pentacarboxymethyldiethylenetriamine
 xref: Beilstein:1810219;   CAS:67-43-6;   Drug_Central:2092;   Gmelin:41509;   LINCS:LSM-5524
 xref_mesh: MESH:D004369
 xref: Wikipedia:Pentetate
 cyclic_relationship: is_conjugate_acid_of CHEBI:35764


show annotations for term's descendants           Sort by:
pentetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I multiple interactions ISO [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein]; Pentetic Acid inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein] CTD PMID:12576517 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoa2 apolipoprotein A-II multiple interactions ISO [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein]; Pentetic Acid inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein] CTD PMID:12576517 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Casp3 caspase 3 increases activity ISO Pentetic Acid results in increased activity of CASP3 protein CTD PMID:17169355 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 increases activity ISO Pentetic Acid results in increased activity of CASP9 protein CTD PMID:17169355 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cp ceruloplasmin multiple interactions ISO Pentetic Acid inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] CTD PMID:22824865 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309 		JBrowse link
G Gh growth hormone multiple interactions ISO Pentetic Acid promotes the reaction [alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]] CTD PMID:10720163 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Pentetic Acid inhibits the reaction [Zinc Sulfate results in decreased expression of IGF1 mRNA] CTD PMID:9685221 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Pentetic Acid inhibits the reaction [[Silicon Dioxide co-treated with ferric chloride] results in increased expression of IL1B mRNA] CTD PMID:28512001 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Pentetic Acid results in decreased expression of MT1A mRNA CTD PMID:21636019 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased activity of PARP1 protein] CTD PMID:21424779 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G S100a2 S100 calcium binding protein A2 multiple interactions ISO Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]; Pentetic Acid inhibits the reaction [S100A2 protein binds to S100A2 protein] CTD PMID:21924240 NCBI chr 3:90,497,554...90,498,815
Ensembl chr 3:90,467,670...90,498,838 		JBrowse link
G S100a4 S100 calcium binding protein A4 multiple interactions ISO Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A4 protein binds to S100A4 protein]] CTD PMID:21924240 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352 		JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 multiple interactions ISO Pentetic Acid affects the reaction [SLC30A1 protein affects the transport of Zinc] CTD PMID:21775119 NCBI chr 1:191,638,810...191,645,359
Ensembl chr 1:191,638,879...191,645,359 		JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 increases expression EXP Pentetic Acid results in increased expression of SLC39A10 mRNA; Pentetic Acid results in increased expression of SLC39A10 protein CTD PMID:21738690 NCBI chr 1:46,846,704...46,964,952
Ensembl chr 1:46,846,704...46,932,012 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Pentetic Acid inhibits the reaction [[Silicon Dioxide co-treated with ferric chloride] results in increased expression of TNF mRNA] CTD PMID:28512001 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]; Pentetic Acid inhibits the reaction [pyrithione zinc results in increased phosphorylation of TP53 protein] CTD PMID:21557991 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO Pentetic Acid promotes the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides] CTD PMID:20457604 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    role 22167
      chemical role 21414
        ligand 6867
          chelator 6851
            copper chelator 659
              pentetic acid 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      carbon group element atom 21909
                        carbon atom 21835
                          organic molecular entity 21835
                            heteroorganic entity 21490
                              organochalcogen compound 20980
                                organooxygen compound 20821
                                  carbon oxoacid 19614
                                    carboxylic acid 19610
                                      pentacarboxylic acid 17
                                        pentetic acid 17
paths to the root