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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pentacarboxylic acid
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Accession:CHEBI:35743 term browser browse the term
Definition:An oxoacid containing five carboxy groups.
Synonyms:related_synonym: pentacarboxylic acids


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pentetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 multiple interactions ISO [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein]; Pentetic Acid inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA1 protein] CTD PMID:12576517 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 multiple interactions ISO [Butylated Hydroxytoluene co-treated with Pentetic Acid] inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein]; Pentetic Acid inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased oxidation of APOA2 protein] CTD PMID:12576517 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Casp3 caspase 3 increases activity ISO Pentetic Acid results in increased activity of CASP3 protein CTD PMID:17169355 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO Pentetic Acid results in increased activity of CASP9 protein CTD PMID:17169355 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cp ceruloplasmin multiple interactions ISO Pentetic Acid inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] CTD PMID:22824865 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Pentetic Acid promotes the reaction [alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]] CTD PMID:10720163 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP Pentetic Acid inhibits the reaction [Zinc Sulfate results in decreased expression of IGF1 mRNA] CTD PMID:9685221 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Pentetic Acid inhibits the reaction [[Silicon Dioxide co-treated with ferric chloride] results in increased expression of IL1B mRNA] CTD PMID:28512001 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP Pentetic Acid results in decreased expression of MT1A mRNA CTD PMID:21636019 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased activity of PARP1 protein] CTD PMID:21424779 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G S100a2 S100 calcium binding protein A2 multiple interactions ISO Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]; Pentetic Acid inhibits the reaction [S100A2 protein binds to S100A2 protein] CTD PMID:21924240 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions ISO Pentetic Acid inhibits the reaction [Copper promotes the reaction [S100A4 protein binds to S100A4 protein]] CTD PMID:21924240 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions EXP Pentetic Acid affects the reaction [SLC30A1 protein affects the transport of Zinc] CTD PMID:21775119 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc39a10 solute carrier family 39 member 10 increases expression ISO Pentetic Acid results in increased expression of SLC39A10 mRNA; Pentetic Acid results in increased expression of SLC39A10 protein CTD PMID:21738690 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Pentetic Acid inhibits the reaction [[Silicon Dioxide co-treated with ferric chloride] results in increased expression of TNF mRNA] CTD PMID:28512001 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]; Pentetic Acid inhibits the reaction [pyrithione zinc results in increased phosphorylation of TP53 protein] CTD PMID:21557991 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP Pentetic Acid promotes the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides] CTD PMID:20457604 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      chemical role 19336
        donor 18644
          Bronsted acid 18526
            oxoacid 18488
              carbon oxoacid 18369
                carboxylic acid 18364
                  pentacarboxylic acid 17
                    Fumonisin C1 0
                    Fumonisin C2 0
                    Fumonisin FP2 0
                    Fumonisin FP3 0
                    G b G b1-G 0
                    Grahamine E, (rel)-1 0
                    Lepranthin 0
                    N-formylmethanofuran 0
                    S b G b1-G 0
                    lignin cw compound-193 0
                    lignin cw compound-3009 0
                    pentetic acid 17
                    staphyloferrin A + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        pentacarboxylic acid 17
                                          Fumonisin C1 0
                                          Fumonisin C2 0
                                          Fumonisin FP2 0
                                          Fumonisin FP3 0
                                          G b G b1-G 0
                                          Grahamine E, (rel)-1 0
                                          Lepranthin 0
                                          N-formylmethanofuran 0
                                          S b G b1-G 0
                                          lignin cw compound-193 0
                                          lignin cw compound-3009 0
                                          pentetic acid 17
                                          staphyloferrin A + 0
paths to the root