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ONTOLOGY REPORT - ANNOTATIONS

Term:gluconeogenesis
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Accession:GO:0006094 term browser browse the term
Definition:The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
Synonyms:exact_synonym: glucose biosynthesis;   glucose biosynthetic process
 xref: MetaCyc:GLUCONEO-PWY;   MetaCyc:PWY-6142;   MetaCyc:PWY66-399;   Reactome:R-HSA-70263 "Gluconeogenesis";   Wikipedia:Gluconeogenesis


show annotations for term's descendants           Sort by:
gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071101.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 8:102,248,821...102,250,215 JBrowse link
G AC110981.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:80,960,086...80,960,928 JBrowse link
G Aldob aldolase, fructose-bisphosphate B involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C involved_in IEA
ISO 		GO_REF:0000107
(PMID:24958256) 		Ensembl
RGD		 PMID:24958256 GO_REF:0000107 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133 		JBrowse link
G Atf3 activating transcription factor 3 acts_upstream_of_or_within ISO (PMID:11916968) RGD PMID:11916968 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Atf4 activating transcription factor 4 acts_upstream_of_or_within ISO (PMID:11916968) RGD PMID:11916968 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16148943)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16148943 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:178,007,233...178,017,397
Ensembl chr 2:178,007,240...178,017,389 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20852621) 		UniProt
RGD		 PMID:20852621 GO_REF:0000024 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:30679508) RGD PMID:30679508 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003 		JBrowse link
G Eno2 enolase 2 IDA RGD PMID:15720133 RGD:2302795 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220 		JBrowse link
G ENSRNOG00000066746 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117
G Fbp1 fructose-bisphosphatase 1 involved_in IDA
IBA
ISO
IEA 		GO_REF:0000033
(PMID:30150719)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000043
(PMID:19259699), (PMID:20096900)
GO_REF:0000041 		GO_Central
RGD
UniProt
Ensembl		 PMID:19259699 PMID:20096900 PMID:30150719 PMID:4353083 PMID:11440903 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:2302851, RGD:2302970 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 involved_in IDA
IBA
IEA 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000043
GO_REF:0000041 		GO_Central
UniProt
RGD		 PMID:4353083 PMID:11440903 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000117, RGD:2302851, RGD:2302970 NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 involved_in TAS
ISO
IEA
IBA
IDA 		(PMID:33359667)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000043
GO_REF:0000104
GO_REF:0000033
GO_REF:0000041
(PMID:8211187) 		RGD
UniProt
Ensembl
GO_Central		 PMID:8211187 PMID:33359667 PMID:8865366 PMID:11440903 PMID:4353083 More... GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117, RGD:728661, RGD:2302970, RGD:2302851, RGD:2302850 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 involved_in IDA
ISO
IEA
IBA 		(PMID:15661744)
GO_REF:0000043
GO_REF:0000107
GO_REF:0000033
GO_REF:0000041 		RGD
UniProt
Ensembl
GO_Central		 PMID:15661744 PMID:4303362 PMID:11440903 PMID:4353083 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107, RGD:2302850, RGD:2302970, RGD:2302851 NCBI chr10:87,647,149...87,651,385
Ensembl chr10:87,647,062...87,653,453 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in IDA
ISO
IEA
IMP 		(PMID:28258188)
GO_REF:0000117 		RGD
UniProt		 PMID:28258188 PMID:15720133 PMID:28258188 GO_REF:0000117, RGD:2302795, RGD:13792662 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377 		JBrowse link
G Gapdhl3 glyceraldehyde-3-phosphate dehydrogenase like 3 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr15:83,731,940...83,879,072 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17545671) 		Ensembl
RGD		 PMID:17545671 GO_REF:0000107 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO (PMID:12093800) RGD PMID:12093800 NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 acts_upstream_of_or_within ISO MGI:2387347 (PMID:12093800) RGD PMID:12093800 NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in IEA
IBA 		GO_REF:0000043
GO_REF:0000002
GO_REF:0000033 		UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 IMP RGD PMID:25865565 RGD:11342811 NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616 		JBrowse link
G LOC108352348 glyceraldehyde-3-phosphate dehydrogenase pseudogene involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:82,362,722...82,372,112 JBrowse link
G LOC134480898 glyceraldehyde-3-phosphate dehydrogenase-like involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr10:99,312,710...99,314,761
Ensembl chr10:99,312,829...99,314,552 		JBrowse link
G Mdh2 malate dehydrogenase 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12581790) 		Ensembl
RGD		 PMID:12581790 GO_REF:0000107 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:26,530,881...26,543,841 		JBrowse link
G Mir100hgl Mir100 Mirlet7a-2 Mir125b-1 cluster host gene like involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:50,595,904...50,860,909 JBrowse link
G Pc pyruvate carboxylase involved_in IDA
IEA
IBA 		GO_REF:0000117
GO_REF:0000002
GO_REF:0000043
GO_REF:0000033
GO_REF:0000041 		UniProt
InterPro
GO_Central
RGD		 PMID:4353083 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000117, RGD:2302851 NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within 		TAS
ISO
IEA
IBA
IDA 		MGI:2449283|MGI:2449284 (PMID:10938127), (PMID:15347677), (PMID:19643083), (PMID:29230018), (PMID:34156032)
(PMID:11916968)
GO_REF:0000117
GO_REF:0000002
GO_REF:0000043
GO_REF:0000033
(PMID:26971250), (PMID:30193097)
GO_REF:0000041
PMID:4186849 		RGD
UniProt
InterPro
GO_Central		 PMID:10938127 PMID:11916968 PMID:15347677 PMID:19643083 PMID:26971250 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000117, RGD:625518, RGD:8553288, RGD:2302971, RGD:2302970, RGD:2302851, RGD:2302850 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in IDA
ISO
IEA
IBA 		MGI:97501 (PMID:23466304)
GO_REF:0000117
GO_REF:0000043
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
GO_REF:0000041 		RGD
UniProt
Ensembl
InterPro
GO_Central		 PMID:23466304 PMID:4353083 PMID:6049928 PMID:11440903 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:2302851, RGD:2302971, RGD:2302970 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864 		JBrowse link
G Per2 period circadian regulator 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:22504074) 		UniProt
RGD		 PMID:22504074 GO_REF:0000024 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in NAS PMID:15581487 ComplexPortal PMID:15581487 RGD:598277139 NCBI chr  X:22,936,038...22,989,691
Ensembl chr  X:22,937,494...22,989,704 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 involved_in NAS PMID:15581487 ComplexPortal PMID:15581487 RGD:598277139 NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 involved_in NAS PMID:15581487 ComplexPortal PMID:15581487 RGD:598277139 NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 involved_in NAS PMID:15581487 ComplexPortal PMID:15581487 RGD:598277139 NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:24958256) RGD PMID:24958256 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 IDA RGD PMID:15720133 RGD:2302795 NCBI chr14:84,895,763...84,897,874
Ensembl chr14:84,895,744...84,897,894 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in IDA
ISO
IEA
IBA
IMP 		MGI:106918 (PMID:19643083)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19643083 PMID:15720133 PMID:3091090 GO_REF:0000033 GO_REF:0000107, RGD:2302795, RGD:2302860 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:75,336,687...75,352,959 		JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:44,487,980...44,489,330
Ensembl chr 2:44,488,018...44,489,235 		JBrowse link
G Pgk2 phosphoglycerate kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:27,976,913...27,978,479
Ensembl chr 9:27,973,459...28,079,866 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha involved_in IEP
ISO
IEA
ISS 		(PMID:15716268)
GO_REF:0000117
(PMID:16753578), (PMID:23142079)
GO_REF:0000024 		RGD
UniProt		 PMID:15716268 PMID:16753578 PMID:23142079 PMID:21212096 GO_REF:0000024 GO_REF:0000117, RGD:9585757 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO
IEA 		(PMID:18466349)
(PMID:16034410)
GO_REF:0000107 		RGD
Ensembl		 PMID:16034410 PMID:18466349 GO_REF:0000107 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898 		JBrowse link
G Sds serine dehydratase involved_in TAS
IEA 		GO_REF:0000043
GO_REF:0000041 		UniProt
RGD		 PMID:11906824 GO_REF:0000041 GO_REF:0000043, RGD:633956 NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 involved_in IEA
ISO 		GO_REF:0000107
(PMID:35507647) 		Ensembl
RGD		 PMID:35507647 GO_REF:0000107 NCBI chr10:55,856,209...55,859,060
Ensembl chr10:55,855,979...55,859,060 		JBrowse link
G Slc25a13 solute carrier family 25 member 13 involved_in IEA
ISO 		GO_REF:0000107
MGI:3028639 (PMID:14701727) 		Ensembl
RGD		 PMID:14701727 GO_REF:0000107 NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360 		JBrowse link
G Slc37a4 solute carrier family 37 member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:28973635) 		Ensembl
RGD		 PMID:28973635 GO_REF:0000107 NCBI chr 8:53,619,952...53,626,110
Ensembl chr 8:53,620,141...53,626,110 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 acts_upstream_of ISO (PMID:21445361) RGD PMID:21445361 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in IEA
ISO
IBA 		GO_REF:0000041
(PMID:31891762)
GO_REF:0000043
GO_REF:0000033 		UniProt
RGD
GO_Central		 PMID:31891762 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413 		JBrowse link
G Tpi1l1 triosephosphate isomerase 1 like 1 involved_in IEA
IBA 		GO_REF:0000041
GO_REF:0000043
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr 8:31,923,596...31,931,244
Ensembl chr 8:31,923,232...31,931,327 		JBrowse link
G Tpi1l2 triosephosphate isomerase 1 like 2 involved_in IEA
IBA 		GO_REF:0000041
GO_REF:0000043
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr17:27,307,380...28,230,998
Ensembl chr17:27,306,345...27,308,391 		JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of_or_within ISO (PMID:11479628) RGD PMID:11479628 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:22275362) 		GO_Central
RGD		 PMID:22275362 GO_REF:0000033 NCBI chr 5:171,833,854...171,838,229
Ensembl chr 5:171,833,854...171,838,800 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within
involved_in 		ISO (PMID:20952387) RGD PMID:20952387 NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559 		JBrowse link
G Clk2 CDC-like kinase 2 involved_in ISO (PMID:20074525) RGD PMID:20074525 NCBI chr 2:176,868,423...176,880,412
Ensembl chr 2:176,869,490...176,880,411 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28790135), (PMID:29937374) 		UniProt
RGD		 PMID:28790135 PMID:29937374 GO_REF:0000024 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Ep300 EP300 lysine acetyltransferase involved_in ISO (PMID:30193097) RGD PMID:30193097 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Erfe erythroferrone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:99,404,512...99,412,383
Ensembl chr 9:99,404,514...99,412,383 		JBrowse link
G Gck glucokinase involved_in ISO
IEA
ISS 		(PMID:8878425)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:8878425 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Il6 interleukin 6 IDA In liver RGD PMID:16308834 RGD:2306940 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8069456) RGD PMID:8069456 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO
IEA 		(PMID:16753578), (PMID:23142079)
GO_REF:0000107 		RGD
Ensembl		 PMID:16753578 PMID:23142079 GO_REF:0000107 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485 		JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:1856009 (PMID:24051374) RGD PMID:24051374 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Mst1 macrophage stimulating 1 involved_in ISO (PMID:19720831) RGD PMID:19720831 NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015 		JBrowse link
G Mtcl2 microtubule crosslinking factor 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20813965) 		Ensembl
RGD		 PMID:20813965 GO_REF:0000107 NCBI chr 3:166,089,141...166,161,043
Ensembl chr 3:166,095,480...166,161,102 		JBrowse link
G Mup4l1 major urinary protein 4 like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:80,223,093...80,226,566 JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in ISO
IEA 		(PMID:19651776)
GO_REF:0000107 		RGD
Ensembl		 PMID:19651776 GO_REF:0000107 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (PMID:21135134) RGD PMID:21135134 NCBI chr 3:28,904,024...28,907,391
Ensembl chr 3:28,902,876...28,907,389 		JBrowse link
G Pgp phosphoglycolate phosphatase involved_in IMP
IEA
ISO 		PMID:26755581
GO_REF:0000107
(PMID:26755581) 		Ensembl
RGD		 PMID:26755581 PMID:26755581 GO_REF:0000107, RGD:10679995 NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408 		JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within ISO (PMID:22837305) RGD PMID:22837305 NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:128,717,334...128,732,049 		JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16148943)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16148943 GO_REF:0000024 GO_REF:0000107 NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:23142079), (PMID:25009184) RGD PMID:23142079 PMID:25009184 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,732,974...8,738,542 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 IMP RGD PMID:21901280 RGD:152995490 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28655758) 		UniProt
Ensembl
RGD		 PMID:28655758 GO_REF:0000024 GO_REF:0000107 NCBI chr10:7,335,508...7,432,018
Ensembl chr10:7,367,604...7,432,013 		JBrowse link
positive regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpp19 cAMP-regulated phosphoprotein 19 involved_in ISO (PMID:9653196) RGD PMID:9653196 NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (PMID:29937374) RGD PMID:29937374 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Ctdspl2 CTD small phosphatase like 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28851713)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28851713 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IMP RGD PMID:29656108 RGD:150520032 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28790135) 		UniProt
RGD		 PMID:28790135 GO_REF:0000024 NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566 		JBrowse link
G Foxo1 forkhead box O1 involved_in
acts_upstream_of_or_within 		ISS
ISO
IBA 		GO_REF:0000024
(PMID:17024043), (PMID:25009184)
(PMID:12783775)
GO_REF:0000033 		UniProt
RGD
GO_Central		 PMID:12783775 PMID:17024043 PMID:25009184 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Gcg glucagon acts_upstream_of_or_within ISO (PMID:24051374) RGD PMID:24051374 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:67,522,489...67,531,533 		JBrowse link
G Gpt glutamic--pyruvic transaminase IDA RGD PMID:25865565 RGD:11342811 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:24177414 RGD:10445837 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in IMP
IDA 		PMID:19651776 RGD
BHF-UCL		 PMID:16893891 PMID:24177414 PMID:19651776 RGD:1624992, RGD:10445837, RGD:8553501 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
MGI:95674 (PMID:24051374) 		UniProt
RGD		 PMID:24051374 GO_REF:0000117 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
MGI:2155884|MGI:95674 (PMID:24051374) 		UniProt
RGD		 PMID:24051374 GO_REF:0000117 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616 		JBrowse link
G Nnmt nicotinamide N-methyltransferase involved_in ISO (PMID:26168293) RGD PMID:26168293 NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174 		JBrowse link
G Oprm1 opioid receptor, mu 1 IMP RGD PMID:34270714 RGD:401831046 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO MGI:1857774 (PMID:15232616) RGD PMID:15232616 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha involved_in ISO (PMID:19651776) RGD PMID:19651776 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppp4r3a protein phosphatase 4, regulatory subunit 3A involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
(PMID:20876121) 		UniProt
RGD		 PMID:20876121 GO_REF:0000117 NCBI chr 6:126,032,068...126,098,329
Ensembl chr 6:126,032,068...126,095,543 		JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B acts_upstream_of_or_within ISO (PMID:20876121) RGD PMID:20876121 NCBI chr14:107,118,116...107,166,121
Ensembl chr14:107,118,131...107,166,134 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in NAS PMID:11903059 UniProt PMID:11903059 RGD:8554594 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:23292513) 		Ensembl
RGD		 PMID:23292513 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:131,842,058...131,859,484
Ensembl chr 7:131,842,060...131,859,503 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939 		JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:83,744,385...83,753,629
Ensembl chr 9:83,744,385...83,753,729 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:20484139) 		UniProt
Ensembl
RGD		 PMID:20484139 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
G Sirt1 sirtuin 1 involved_in IMP
ISO
IEA 		(PMID:15692560), (PMID:23142079), (PMID:30193097)
GO_REF:0000107
(PMID:26168293) 		RGD
Ensembl		 PMID:15692560 PMID:23142079 PMID:26168293 PMID:30193097 PMID:21212096 GO_REF:0000107, RGD:9585757 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sirt7 sirtuin 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:28655758) 		UniProt
RGD		 PMID:28655758 GO_REF:0000024 NCBI chr10:106,394,802...106,401,627
Ensembl chr10:106,394,802...106,401,498 		JBrowse link
G Stk11 serine/threonine kinase 11 IMP RGD PMID:17083919 RGD:2291956 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:5430317 (PMID:23260145) RGD PMID:23260145 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225 		JBrowse link
G Wdr5 WD repeat domain 5 acts_upstream_of_or_within ISO MGI:1343094|MGI:95674 (PMID:24051374) RGD PMID:24051374 NCBI chr 3:31,233,048...31,254,730
Ensembl chr 3:31,235,222...31,254,727 		JBrowse link
regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain involved_in IEA
ISO 		GO_REF:0000107
(PMID:18459129) 		Ensembl
RGD		 PMID:18459129 GO_REF:0000107 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISO (PMID:29937374) RGD PMID:29937374 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:23767959) RGD PMID:23767959 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,203,565...1,218,024 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO
ISS
IEA 		(PMID:7558035)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:7558035 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746 		JBrowse link
G Foxo1 forkhead box O1 acts_upstream_of_or_within ISO (PMID:18497885) RGD PMID:18497885 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Gnmt glycine N-methyltransferase involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3842652 (PMID:17937387) 		GO_Central
RGD		 PMID:17937387 GO_REF:0000033 NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692 		JBrowse link
G Insr insulin receptor IEP RGD PMID:29896241 RGD:14700925 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1856424 (PMID:16513828) RGD PMID:16513828 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Nln neurolysin acts_upstream_of_or_within ISO MGI:4125183 (PMID:24719317) RGD PMID:24719317 NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within ISO MGI:1857745 (PMID:7628695) RGD PMID:7628695 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:23395176)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:23395176 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:70,811,319...70,856,123 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:22360721) 		UniProt
RGD		 PMID:22360721 GO_REF:0000024 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Ranbp2 RAN binding protein 2 acts_upstream_of_or_within ISO MGI:3693886 (PMID:17069463) RGD PMID:17069463 NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571 		JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO MGI:3587950 (PMID:22958918) RGD PMID:22958918 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255 		JBrowse link
G Slc35b4 solute carrier family 35 member B4 acts_upstream_of_or_within ISO (PMID:21507882) RGD PMID:21507882 NCBI chr 4:63,744,188...63,766,200
Ensembl chr 4:63,744,188...63,766,196 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within
involved_in 		ISO
IBA 		MGI:4431951 (PMID:23028378)
GO_REF:0000033 		RGD
GO_Central		 PMID:23028378 GO_REF:0000033 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225 		JBrowse link
G Zfp692 zinc finger protein 692 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21910974) 		UniProt
Ensembl
RGD		 PMID:21910974 GO_REF:0000024 GO_REF:0000107 NCBI chr10:42,988,946...42,997,009
Ensembl chr10:42,988,938...42,997,015 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18845
      metabolic process 11694
        biosynthetic process 8313
          small molecule biosynthetic process 679
            monosaccharide biosynthetic process 119
              hexose biosynthetic process 113
                gluconeogenesis 110
                  negative regulation of gluconeogenesis 23
                  positive regulation of gluconeogenesis 30
                  regulation of gluconeogenesis + 64
Path 2
Term Annotations click to browse term
  biological_process 19688
    cellular process 18845
      metabolic process 11694
        primary metabolic process 10271
          carbohydrate metabolic process 617
            monosaccharide metabolic process 306
              hexose metabolic process 283
                glucose metabolic process 247
                  gluconeogenesis 110
                    negative regulation of gluconeogenesis 23
                    positive regulation of gluconeogenesis 30
                    regulation of gluconeogenesis + 64
paths to the root